CN112932996A

CN112932996A - Whitening composition and essence thereof

Info

Publication number: CN112932996A
Application number: CN202110148148.XA
Authority: CN
Inventors: 姚哲男; 舒鹏
Original assignee: Shenzhen Hujia Technology Co ltd
Current assignee: Shenzhen Hujia Technology Co ltd
Priority date: 2021-02-03
Filing date: 2021-02-03
Publication date: 2021-06-11

Abstract

The invention relates to the technical field of cosmetics, in particular to a whitening composition and essence thereof. A whitening composition comprising a lipid component, a humectant, and a whitening agent; the lipid component comprises a liquid phase oil component and a water phase component containing an amino acid type zwitterionic surfactant, wherein the mass ratio of the liquid phase oil component to the water phase component is (0.1-0.5): 1. The whitening composition can promote normal growth of cells, inhibit synthesis of pigment, block pigment transfer, and improve whitening effect; meanwhile, the skin whitening composition has a synergistic effect with a specific wrapping technology, realizes the slow release of the whitening active ingredients, effectively permeates the skin and fully exerts the long-term stable whitening effect.

Description

Whitening composition and essence thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a whitening composition and essence thereof.

Background

The skin is composed of epidermis, dermis, and subcutaneous tissue. The epidermis is composed of keratinized stratified squamous epithelium, including stratum corneum, stratum lucidum, stratum granulosum, spinous layer and stratum basale from the outside to the inside. Melanocyte is located in basal layer of epidermis, and is spherical cell body, and branched dendrite of cell with different length is arranged on the melanocyte; melanin is produced by melanocytes, and the quantity and distribution of melanin are major factors for determining skin color. Melanin is a protein present in the basal layer of the skin of everyone. The irradiation of ultraviolet rays can change melanin to generate a substance for protecting skin, and then the melanin moves layer by layer through cell metabolism to reach the epidermis layer of the skin, so that the skin problems of color spots, uneven skin color and the like seen by people are formed. Because of the traditional beauty concept of 'one white covering three ugly', whitening is always a permanent pursuit of women and is also a nursing project from inside to outside.

The commercially available whitening products come out endlessly, however, the existing whitening skin care product system has many disadvantages: most of the whitening active ingredients have poor stability, are easy to oxidize and deteriorate and discolor in the process of placing the product to lose the whitening effect, and seriously influence the service life and the effectiveness of the product; some whitening active ingredients can cause skin irritation, allergy and the like; due to the skin barrier, the whitening active ingredients are difficult to penetrate through the horny layer to enter the skin basal layer, so that the whitening effect is greatly reduced; part of the whitening agents are powder, are easy to dissolve in oil and water, are difficult to stably and uniformly disperse in water, and are easy to have unstable quality phenomena such as precipitation, floccule generation, layering and the like.

In order to solve the above problems, it is desirable to provide a whitening composition to achieve the function of promoting normal growth of cells, inhibit synthesis of pigments, block pigment transport, and improve whitening efficacy; meanwhile, the stability of the whitening composition needs to be improved, so that the whitening active ingredients can be slowly released and effectively permeate through the skin, and the long-term stable whitening effect of the whitening composition is fully exerted.

Disclosure of Invention

Unless otherwise indicated, implied from the context, or customary in the art, all parts and percentages herein are by weight and the testing and characterization methods used are synchronized with the filing date of the present application. To the extent that a definition of a particular term disclosed in the prior art is inconsistent with any definitions provided herein, the definition of the term provided herein controls.

The technical features of the technical solutions provided by the present invention are further clearly and completely described below with reference to the specific embodiments, and the scope of protection is not limited thereto.

The words "preferred", "preferably", "more preferred", and the like, in the present invention, refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. Furthermore, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention. The sources of components not mentioned in the present invention are all commercially available.

The inventors of the present invention have conducted extensive studies to solve the above problems and have found that a whitening composition, which is applied to the encapsulation of a whitening agent, exhibits superior particle stability.

The first aspect of the present invention provides a whitening composition comprising a lipid component, a humectant, and a whitening agent; furthermore, the composition comprises 1-5% of a humectant, 0.2-3% of a whitening agent and the balance of a lipid component by mass percentage.

Wherein the lipid component comprises a liquid phase oil component and an aqueous phase component containing an amino acid type zwitterionic surfactant, wherein the mass ratio of the liquid phase oil component to the aqueous phase component is (0.1-0.5): 1, preferably (0.2-0.4): 1.

As the liquid-phase oil component, at least a silicone-based compound is preferably included; examples of the silicone compound that can be used in the present invention include, but are not limited to, dimethylpolysiloxane having a hydroxyl terminal group, methylphenylpolysiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, polyether-modified silicone, amino-modified silicone, betaine-modified silicone, alkyl-modified silicone, alkoxy-modified silicone, mercapto-modified silicone, carboxyl-modified silicone, fluorine-modified silicone, and the like.

In the studies on the silicone-based compounds, it was found that, in particular, when the silicone-based compounds include (a) polyether-modified silicone and (b) alkylsiloxane, good high-temperature stability is obtained and good particle morphology is maintained.

As a result of experiments on polyether-modified silicones having different viscosities in the study as (a) the polyether-modified silicone of the present invention, it was found that the viscosity at 25 ℃ is 5000mpa.s or less, and most preferably the viscosity at 25 ℃ is 4000mpa.s or less.

Examples of the polyether-modified silicone include PEG-10 dimethylpolysiloxane, PEG-11 dimethylpolysiloxane, and particularly preferably PEG-3 dimethylpolysiloxane, PEG-7 dimethylpolysiloxane, PEG-8 dimethylpolysiloxane, PEG-9 dimethylpolysiloxane, PEG-12 dimethylpolysiloxane, PEG-14 dimethylpolysiloxane, PEG-17 dimethylpolysiloxane, PEG-6 methylether dimethylpolysiloxane, PEG-7 methylether dimethylpolysiloxane, PEG-8 methylether dimethylpolysiloxane, PEG-9 methylether dimethylpolysiloxane, PEG-10 methylether dimethylpolysiloxane, PEG-11 methylether dimethylpolysiloxane, PEG-, PEG-32 methyl ether dimethylpolysiloxane, PEG-9 polydimethylsiloxyethyl dimethylpolysiloxane, lauryl PEG-9 polydimethylsiloxyethyl dimethylpolysiloxane, methoxy PEG/PPG-25/4 polydimethylsiloxane, bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane; the polyether-modified silicone may be used alone or in combination of two or more; preferably, the polyether-modified silicone (a) of the present invention is at least one selected from the group consisting of PEG-9 Dimethylsiloxyethyldimethylpolysiloxane, lauryl PEG-9 Dimethylsiloxyethyldimethylpolysiloxane, methoxy PEG/PPG-25/4 Dimethicone, bis-PEG/PPG-20/5 PEG/PPG-20/5 Dimethicone. Specifically, the (a) polyether modified silicone which is proved to be better comprises (a1) methoxy PEG/PPG-25/4 polydimethylsiloxane and (a2) bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane.

METHOXY PEG/PPG-25/4 polydimethylsiloxane and BIS-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane as polyether modified silicone, and the common names of the cosmetics are METHOXY PEG/PPG-25/4, DIMETHICONE, BIS-PEG/PPG-20/5 and PEG/PPG-20/5 DIMETHICONE respectively; in the research, the contents of polyoxyethylene and polyoxypropylene in the system are further adjusted by changing the respective proportions of the polyoxyethylene and polyoxypropylene, so that the stability of the wrapping material can be obviously improved.

As examples of the alkyl siloxane (b), there may be mentioned polydimethylsiloxane, cyclomethicone, cyclophenylpmethicone, octyldimethicone, octyltrimethicone, octylmethicone, cetearyl methicone, hexadecylmethicone, hexylmethicone, lauryl methicone, myristyl methicone, phenyl methicone, stearyl dimethicone, trifluoropropyl methicone, cetyl dimethicone, polyphenylmethylsiloxane, dimethylpolysiloxane, tolylpolysiloxane, cyclopentyldimethicone, decamethylcyclopentadimethicone, cyclohexasiloxane, cycloheptasiloxane, cyclotetrasimethylsiloxane, cyclotrimeric dimethicone, cyclomethicone, and the like, Methyl trimethicone, diphenyl siloxy phenyl trimethicone, octyl methicone and phenyl trimethicone.

These alkyl siloxanes may be used alone or in combination in any ratio of a plurality of the above, preferably at least one of polydimethylsiloxane, cyclomethicone, cyclophenylpolymethicone, cyclopentadimethicone, decamethylcyclopentamethicone, cyclohexasiloxane, cycloheptasiloxane, and most preferably (b) alkyl siloxanes including (b1) cyclopentadimethicone and (b2) cyclohexasiloxane; the similar structures of the cyclopentadimethylsiloxane and the cyclohexasiloxane enable the emulsification components to interact through the difference of the sizes of the rings, make up for the defect of insufficient emulsification effect, improve the hydrophily and lipophilicity, and can be stably maintained together with the polyether modified silicone (a) in a certain proportion range.

Preferably, in the composition of the present invention, the mass ratio of (a1) methoxy PEG/PPG-25/4 polydimethylsiloxane, (a2) bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane, (b1) cyclopentadimethylsiloxane and (b2) cyclohexasiloxane is stable within a certain range, and the stable time can reach more than 30 days, preferably (a 1): (a2) the method comprises the following steps (b1) The method comprises the following steps (b2) The mass ratio of (5-9): (5-8): (3-7): (3-6); more preferably (5 to 7): (6-7): (4-5): (2-4).

Further, in addition to the above-described preferred (a) polyether-modified silicone, (c) a glyceride compound is included in the liquid-phase oil component. The glyceride compounds are esters of glycerin with fatty acids, and there are many glycerin fatty acid esters, including monoesters, diesters and triesters, depending on the kind of the constituent fatty acids and the position of the ester chain, wherein the triesters (trioleate) are generally a mixture of monoesters, diesters and triesters.

The glyceride compound (c) suitable for the present invention is preferably a glyceride compound having an HLB value of 3 to 10, and examples of the glyceride compound include glyceride compounds such as glyceryl stearate, self-emulsifying glyceryl stearate, glyceryl isostearate, glyceryl diisostearate, and caprylic/capric triglyceride is most preferably caprylic/capric triglyceride. Caprylic/capric triglyceride is one of the liquid-phase oil components of the present invention, and the caprylic/capric triglyceride expands the range of the original HLB value by the combined action with (a) polyether-modified silicone and (b) alkyl siloxane in the liquid-phase oil component, further improves the emulsifying ability, and maintains the stability, and the mass ratio of (a) polyether-modified silicone, (b) alkyl siloxane, and (c) glyceride compound is preferably (5-7): (3-4): 1.

In the whitening composition of the invention, an amino acid type zwitterionic surfactant is preferably added into the water phase component, and the mass concentration of the amino acid type zwitterionic surfactant in the water phase component is preferably 1-15%, and more preferably 5-6%.

The amino acid type zwitterionic surfactant is preferably an amino acid type zwitterionic surfactant with 12-40 total carbon atoms, more preferably an amino acid type zwitterionic surfactant with 20-40 total carbon atoms, and particularly, acyl peptide compounds with 20-40 total carbon atoms are the most suitable amino acid type zwitterionic surfactants in the invention, and include but are not limited to palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. The preferable amino acid type zwitterionic surfactant comprises palmitoyl tripeptide-1 and/or palmitoyl tetrapeptide-7, most preferably a mixture of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and the mass ratio of the palmitoyl tripeptide-1 to the palmitoyl tetrapeptide-7 is (1-2): (1-2), most preferably 1: 1.

Examples of the humectant include polyethylene glycol, propylene glycol, glycerin, butylene glycol, pentylene glycol, betaine, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucin sulfate, carotinoid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile acid salts, dl-pyrrolidone carboxylate, alkylene oxide derivatives, short-chain soluble collagen, diglycerin (EO) PO adducts, filature flower extract, yarrow extract, and melilot extract. Among them, the moisturizer suitable for the present invention preferably includes polyols, preferably butylene glycol and betaine, and sodium hyaluronate, preferably 4D sodium hyaluronate, wherein 4D sodium hyaluronate is commercially available, and INCI includes sodium hyaluronate cross-linked polymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, 1, 2-pentanediol, ethylhexylglycerin, and water. Preferably, the mass ratio of butanediol, betaine and 4D sodium hyaluronate is (0.1-1): 1-2); more preferably (0.3 to 0.6): (0.3 to 0.7): 1 to 2.

The whitening agent of the invention can be wrapped by lipid components and delivered into cells, thus effectively solving the transdermal absorption function of bioactive substances. Such whitening agents may be a plurality of different types or the same type of active substances, or may be a single type of whitening agent, and the composition of the plurality of whitening agents may be adjusted appropriately in consideration of the feeling of use or physiological activity effect.

Examples of the whitening agent include arbutin, glabridin, phloretin, endothelin antagonists, azelaic acid and its derivatives, niacinamide, hesperidin, cysteine, ascorbic acid and its derivatives, gallic acid, tretinoin, alpha-hydroxy acids, fruit acids, salicylic acid, rutin, resveratrol, procyanidin, ellagic acid, tetrahydrocurcumin, ergothioneine, undecenoylphenylalanine, L-ascorbic acid 2-glucoside, procyanidin and niacinamide, 3-o-ethylascorbic acid, glycyrrhetinic acid, N-acetylglucosamine, tranexamic acid, arbutin, catalase, glutathione peroxidase, catalase, metallothionein, ceruloplasmin, transferrin, lactoferrin, albumin, bilirubin, citric acid, tartaric acid, malic acid, azelaic acid and its derivatives, and the like, Phytic acid, histidine, tryptophan, O-phosphono-pyridoxoylidene rhodamine. Among these whitening agents, particularly preferred are whitening agents of the present invention including ergothioneine, 3-o-ethyl ascorbic acid, and glycyrrhetinic acid, wherein the ergothioneine has a function of scavenging free radicals, maintaining DNA biosynthesis, and promoting normal cell growth, and the mass ratio of ergothioneine, 3-o-ethyl ascorbic acid, and glycyrrhetinic acid is preferably (0.1 to 0.5): (0.3 to 0.7): 0.1 to 0.5), more preferably (0.1 to 0.3): 0.3 to 0.5): 0.1 to 0.3. The ergothioneine, the 3-o-ethyl ascorbic acid and the glycyrrhetinic acid are compounded according to the specific proportion, so that the formed whitening composition has the characteristics of good transdermal property, targeting effect and good affinity, can effectively inhibit the activity of tyrosinase, can reduce the formation of active oxygen, can protect cells from radiation damage, promotes the penetration and absorption of nutrient components, effectively and intensively inhibits the formation of melanin, and can lighten spots and flaws after being continuously used; the skin care product can easily enter the dermis layer, improve the activity of skin cells, enable the skin to become full and elastic, and also can promote the skin to be fine, smooth, natural, white and uniform and bright.

In a second aspect, the present invention provides a whitening essence comprising an emollient, a skin conditioner and the above whitening composition.

The essence disclosed by the invention preferably comprises 0.1-5% of an emollient, 0.1-5% of a skin conditioner and the balance of the whitening composition in percentage by mass.

Allantoin is preferably included as an emollient and the skin conditioner preferably includes rush oil.

In addition, the essence of the present invention may contain components generally used in cosmetics or quasi-drugs in amounts and in amounts that do not impair the effects of the present invention. Examples thereof include polymer emulsions, other oily components, waxes, hydrocarbon oils, higher fatty acids, higher alcohols, synthetic ester oils, coating agents, and ultraviolet absorbers.

Examples of the natural water-soluble polymer include vegetable polymers (e.g., gum arabic, tragacanth gum, galactan, guar gum, locust bean gum, karaya gum, carrageenan, pectin, agar, quince seed (quince), algae colloid (brown algae extract), starch (rice, corn, potato, wheat), and glycyrrhizic acid); microbial polymers (e.g., xanthan gum, dextran, succinoglucan, pullulan, etc.); animal polymers (e.g., collagen, casein, albumin, gelatin, etc.), and the like.

Examples of the semisynthetic water-soluble polymer include starch-based polymers (e.g., carboxymethyl starch, methyl hydroxypropyl starch, etc.); cellulose polymers (methyl cellulose, ethyl cellulose, methylhydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, cellulose powder, etc.); alginic acid polymers (e.g., sodium alginate, propylene glycol alginate, etc.), and the like.

Examples of the water-soluble polymer to be synthesized include vinyl polymers (e.g., polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, carboxyvinyl polymer, etc.); polyoxyethylene polymers (e.g., polyoxyethylene polyoxypropylene copolymers of polyethylene glycol 20,000, 40,000, 60,0000, etc.); acrylic polymers (for example, sodium polyacrylate, polyethylacrylate, polyacrylamide, etc.); a polyethyleneimine; cationic polymers, and the like.

Examples of the oily component include liquid oils and fats, solid oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, and synthetic ester oils.

Examples of the liquid oils and fats include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, almond oil, wheat germ oil, camellia oil, castor oil, linseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil, peanut oil, tea seed oil, torreya oil, rice bran oil, paulownia oil, japanese tung oil, jojoba oil, germ oil, triglycerin, and the like.

Examples of the solid fat and oil include cacao butter, coconut oil, horse fat, hydrogenated coconut oil, palm oil, beef tallow, mutton tallow, hydrogenated beef tallow, palm kernel oil, lard, beef bone fat, beeswax kernel oil, hydrogenated oil, beef foot fat, beeswax, hydrogenated castor oil, and the like.

Examples of the waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, white wax, spermaceti wax, montan wax, rice bran wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax, lanolin fatty acid isopropyl ester, hexyl laurate, reduced lanolin, jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, lanolin fatty acid polyglycol ester, and POE hydrogenated lanolin alcohol ether.

Examples of the hydrocarbon oil include liquid paraffin, ceresin, squalane, pristane, paraffin, ceresin, squalene, vaseline, and microcrystalline wax.

Examples of the higher fatty acid include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, tall oil acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

As the higher alcohol, for example, a straight-chain alcohol (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetearyl alcohol, etc.); branched alcohols (e.g., monostearyl glyceryl ether (batyl alcohol), 2-decyltetradecanol, lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.), etc.

Examples of the synthetic ester oil include isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesterol 12-hydroxystearate, ethylene glycol di (2-ethylhexanoate), dipentaerythritol fatty acid ester, N-alkylene glycol monoisostearate, neopentyl glycol didecanoate, diisostearyl malate, glycerol di (2-heptylundecanoate), trimethylolpropane tri (2-ethylhexanoate), trimethylolpropane triisostearate, pentaerythritol tetra (2-ethylhexanoate), Glyceryl tris (2-ethylhexanoate), glyceryl trioctanoate, glyceryl triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glyceryl trimyristate, glyceryl tris (2-heptylundecanoate), methyl ricinoleate, oleyl oleate, acetyl glycerol, 2-heptylundecyl palmitate, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di (2-heptylundecyl) adipate, ethyl laurate, di (2-ethylhexyl) sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, isopropyl oleate, isopropyl myristate, isopropyl palmitate, 2-ethylhexyl succinate, triethyl citrate, and the like.

Examples of the coating agent include anionic coating agents (e.g., (meth) acrylic acid/(meth) acrylate copolymers, methyl vinyl ether/maleic anhydride polymers, etc.), cationic coating agents (e.g., cationized cellulose, dimethyldiallylammonium chloride polymers, dimethyldiallylammonium chloride/acrylamide copolymers, etc.), and nonionic coating agents (e.g., polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl acetate, polyacrylate copolymers, (meth) acrylamide, high molecular silicone, silicone resins, trimethylsiloxysilicates, etc.).

Examples of the ultraviolet absorber include benzoic acid-based ultraviolet absorbers (e.g., p-aminobenzoic acid (hereinafter abbreviated as "PABA"), PABA monoglyceride, N-dipropoxypPABA ethyl ester, N-diethoxypPABA ethyl ester, N-dimethylpPABA butyl ester, N-dimethylpPABA ethyl ester, etc.); anthranilic acid-based ultraviolet absorbers (e.g., homoyl-N-acetyl anthranilate); salicylic acid-based ultraviolet absorbers (e.g., amyl salicylate, salicylic acid ester, high salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropyl alcohol phenyl salicylate, etc.); cinnamic acid-based ultraviolet absorbers (e.g., octyl methoxycinnamate, ethyl 4-isopropylcinnamate, methyl 2, 5-diisopropylcinnamate, ethyl 2, 4-diisopropylcinnamate, methyl 2, 4-diisopropylcinnamate, propyl p-methoxycinnamate, isopropyl p-methoxycinnamate, isoamyl p-methoxycinnamate, octyl p-methoxycinnamate (2-ethylhexyl p-methoxycinnamate), 2-ethoxyethyl p-methoxycinnamate, cyclohexyl p-methoxycinnamate, ethyl α -cyano- β -phenylcinnamate, 2-ethylhexyl α -cyano- β -phenylcinnamate, glycerol mono-2-ethylhexanoyl-di-p-methoxycinnamate, etc.); benzophenone-based ultraviolet absorbers (e.g., 2, 4-dihydroxybenzophenone, 2' -dihydroxy-4-methoxybenzophenone, 2' -dihydroxy-4, 4' -dimethoxybenzophenone, 2',4,4' -tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4 ' -methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4 ' -phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octyloxybenzophenone, 4-hydroxy-3-carboxybenzophenone, etc.); 3- (4' -methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2' -hydroxy-5-methylphenylbenzotriazole; 2- (2 '-hydroxy-5' -tert-octylphenyl) benzotriazole; 2- (2' -hydroxy-5 ' -methylphenylbenzotriazole, dibenzylhydrazine (ジベンザラジン), dianisiloylmethane, 4-methoxy-4 ' -tert-butyldibenzoylmethane, 5- (3, 3-dimethyl-2-norbornyl) -3-pentan-2-one, dimorpholinopyridazine, 2-ethylhexyl-2-cyano-3, 3-diphenylacrylate, 2, 4-bis- { [4- (2-ethylhexyloxy) -2-hydroxy ] -phenyl } -6- (4-methoxyphenyl) - (1,3,5) -triazine and the like.

The whitening essence provided by the invention realizes the slow release of the whitening composition containing the ergothioneine-coated component under the combined action of the emollient and the skin conditioner and the combination of a specific coating technology, can penetrate into the deep layer of the skin, inhibit the synthesis of pigments, block the transfer of the pigments, enhance the capability of the skin to remove free radicals, improve the oil metabolism of the skin, eliminate the reason of forming color spots from the source and achieve the effects of long-acting and lasting whitening and spot removal.

Detailed Description

The present invention is described in detail below with reference to examples, which are provided for the purpose of further illustration only and are not to be construed as limiting the scope of the present invention, and the insubstantial modifications and adaptations thereof by those skilled in the art based on the teachings of the present invention will still fall within the scope of the present invention.

Example 1

Whitening essence is shown in the following table 1, a clean container is taken, pure water is added into the container, the container is heated and kept at 80-85 ℃, the group C raw materials are added, and the mixture is stirred and dispersed uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 1

Example 2

According to the formula shown in Table 2, a clean container is taken, pure water is added, heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and stirring and dispersing are carried out uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 2

Example 3

According to the formula shown in Table 3, a clean container is taken, pure water is added, heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and stirring and dispersing are carried out uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 3

Example 4

According to the formula shown in Table 4, a clean container is taken, pure water is added, heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and stirring and dispersing are carried out uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 4

Example 5

According to the formula shown in Table 5, a clean container is taken, pure water is added, the heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and the mixture is stirred and dispersed uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 5

Example 6

According to the formula shown in Table 6, a clean container is taken, pure water is added, the heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and the mixture is stirred and dispersed uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 6

Practice ofExample 7

According to the formula shown in Table 7, a clean container is taken, pure water is added, heating and heat preservation are carried out at 80-85 ℃, the raw materials in the group C are added, and stirring and dispersing are carried out uniformly; adding preheated group A raw materials (3000rpm for 18min), cooling with cold water, adding B, D, E raw materials when the temperature is reduced to 45-50 deg.C, stirring to mix the materials uniformly, stopping stirring at 38-40 deg.C, and cooling to room temperature to obtain the essence.

TABLE 7

Evaluation of PerformanceStability: 2ml samples taken from each example were stored at a constant temperature of 45 ℃ for 30 days, the stability of the essence was observed, and the results are recorded in the following table, where O represents the stability; Δ indicates partial stabilization; x represents very unstable. Usability: 28 men and women were selected, and a total of 56 persons were individually prepared by applying 1ml of each sample from each example to the arm, and rating the moisture, sticky and oily feelings of the essence (5 is very good, 4 is good, 3 is general, 2 is not good, 1 is very poor), and giving the average value.

TABLE 8

Claims

1. A whitening composition characterized by comprising a lipid component, a humectant and a whitening agent; the lipid component comprises a liquid phase oil component and a water phase component containing an amino acid type zwitterionic surfactant, wherein the mass ratio of the liquid phase oil component to the water phase component is (0.1-0.5): 1.

2. The composition of claim 1, wherein the liquid phase oil component comprises at least a silicone based compound.

3. The composition of claim 2, wherein the silicone-based compound comprises (a) a polyether-modified silicone and (b) an alkyl siloxane.

4. The composition according to claim 3, wherein the viscosity of the (a) polyether-modified silicone is 5000mPa.s or less at 25 ℃.

5. The composition of claim 4 wherein the liquid phase oil component further comprises (c) a glyceride compound.

6. The composition according to claim 5, wherein the mass ratio of (a) the polyether-modified silicone, (b) the alkylsiloxane, and (c) the glyceride compound is (5-7): (3-4): 1.

7. The composition according to claim 2, wherein the total carbon number of the amino acid type zwitterionic surfactant is 12 to 40.

8. The composition according to claim 7, wherein the total carbon number of the amino acid type zwitterionic surfactant is 20 to 40.

9. The composition according to claim 8, wherein the amino acid type zwitterionic surfactant is an acyl peptide compound with 20-40 total carbon atoms.

10. Whitening essence characterized by comprising an emollient agent, a skin conditioner and the whitening composition according to any one of claims 1 to 9.