CN1128997A - 新的二烷氧基-吡啶基-苯并咪唑衍生物 - Google Patents

新的二烷氧基-吡啶基-苯并咪唑衍生物 Download PDF

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Publication number
CN1128997A
CN1128997A CN95190482A CN95190482A CN1128997A CN 1128997 A CN1128997 A CN 1128997A CN 95190482 A CN95190482 A CN 95190482A CN 95190482 A CN95190482 A CN 95190482A CN 1128997 A CN1128997 A CN 1128997A
Authority
CN
China
Prior art keywords
methyl
compound
benzoglyoxaline
methoxycarbonyl
sulfinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95190482A
Other languages
English (en)
Chinese (zh)
Inventor
P·林堡
G·E·森登
P·O·S·冯昂格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra AB filed Critical Astra AB
Publication of CN1128997A publication Critical patent/CN1128997A/zh
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN95190482A 1994-05-27 1995-05-11 新的二烷氧基-吡啶基-苯并咪唑衍生物 Pending CN1128997A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9400511 1994-05-27
WOPCT/SE94/00511 1994-05-27

Publications (1)

Publication Number Publication Date
CN1128997A true CN1128997A (zh) 1996-08-14

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95190482A Pending CN1128997A (zh) 1994-05-27 1995-05-11 新的二烷氧基-吡啶基-苯并咪唑衍生物

Country Status (18)

Country Link
EP (1) EP0712401A1 (is)
JP (1) JPH09504557A (is)
CN (1) CN1128997A (is)
AU (1) AU2633095A (is)
BR (1) BR9506235A (is)
CA (1) CA2166988A1 (is)
CZ (1) CZ24396A3 (is)
EE (1) EE9600011A (is)
FI (1) FI960367A0 (is)
HU (1) HU9600005D0 (is)
IL (1) IL113604A0 (is)
IS (1) IS4321A (is)
MA (1) MA23563A1 (is)
NO (1) NO960268L (is)
PL (1) PL312692A1 (is)
TN (1) TNSN95062A1 (is)
WO (1) WO1995032959A1 (is)
ZA (1) ZA954125B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
IL142629A0 (en) 1998-11-18 2002-03-10 Astra Ab Improved chemical process and pharmaceutical formulation
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP2086543A2 (en) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
CA2716367C (en) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
WO2010151216A1 (en) 2009-06-25 2010-12-29 Astrazeneca Ab Method for treating a patient at risk for developing an nsaid-associated ulcer
CA2860231A1 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL166209B1 (pl) * 1990-06-20 1995-04-28 Astra Ab Sposób wytwarzania nowych pochodnych benzimidazolu PL
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
WO1995032959A1 (en) 1995-12-07
EE9600011A (et) 1996-04-15
BR9506235A (pt) 1997-08-12
ZA954125B (en) 1995-11-27
JPH09504557A (ja) 1997-05-06
FI960367A (fi) 1996-01-26
EP0712401A1 (en) 1996-05-22
FI960367A0 (fi) 1996-01-26
NO960268D0 (no) 1996-01-23
HU9600005D0 (en) 1996-03-28
IL113604A0 (en) 1995-08-31
MA23563A1 (fr) 1995-12-31
CA2166988A1 (en) 1995-12-07
IS4321A (is) 1996-01-17
AU2633095A (en) 1995-12-21
TNSN95062A1 (fr) 1996-02-06
PL312692A1 (en) 1996-05-13
CZ24396A3 (en) 1996-06-12
NO960268L (no) 1996-01-23

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Legal Events

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C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication