CN112891430A - Novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and preparation method thereof - Google Patents

Novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and preparation method thereof Download PDF

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CN112891430A
CN112891430A CN202110287479.1A CN202110287479A CN112891430A CN 112891430 A CN112891430 A CN 112891430A CN 202110287479 A CN202110287479 A CN 202110287479A CN 112891430 A CN112891430 A CN 112891430A
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parts
traditional chinese
chinese medicine
soluble powder
powder preparation
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吴玙彤
文正常
王璇
张杨子
张晓可
吴仙
潘淑惠
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GUIZHOU INSTITUTE OF ANIMAL HUSBANDRY AND VETERINARY
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GUIZHOU INSTITUTE OF ANIMAL HUSBANDRY AND VETERINARY
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Abstract

The invention provides a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and a preparation method thereof, and relates to the technical field of pullorum disease treatment. The novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 20-30 parts of dandelion, 8-14 parts of purslane, 30-36 parts of Lala seedlings, 30-36 parts of wild chrysanthemum flowers, 18-20 parts of plantain herbs, 8-14 parts of rhizoma atractylodis, 22-28 parts of folium artemisiae argyi, 10-15 parts of houttuynia cordata, 15-22 parts of eucommia ulmoides, 18-24 parts of astragalus membranaceus, 20-24 parts of isatis roots, 15-18 parts of poplar flowers, 18-20 parts of myrobalan, 11-14 parts of andrographis paniculata, 30-35 parts of starch and 80-95 parts of clear water. The medicine formula of the invention is a pure traditional Chinese medicine formula, is mixed and stirred with water, and is administrated by a water feeding mode or is mixed and administrated by a feed stirring mode, the treatment effect is good, the treatment cost is lower, the treatment medicine can not remain in chicken bodies, the treatment side effect is not caused, the medicine is convenient for the chicken to sell and eat at any time, and the taste of the chicken is not influenced.

Description

Novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and preparation method thereof
Technical Field
The invention relates to the technical field of pullorum disease treatment, and particularly relates to a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and a preparation method thereof.
Background
The pullorum disease is an infectious disease caused by salmonella pullorum, a young pheasant has weak resistance to the pullorum disease, can be ill 3-4 days after emerging from the shell, is fast in transmission and high in mortality rate, and is the disease with the greatest harm in a pheasant group. The sick pheasants discharge white loose feces, white lime-like feces conglomerations are adhered around the anus, the skin is dry, cold is feared, and the wings are drooped. The common prevention and treatment method comprises mixing furazolidone 0.03% into feed, and taking for 3 days, or dissolving oxytetracycline 0.05-0.1% in water for drinking, 5-7 days as a treatment course. Although the prevention and treatment method is low in cost, the treatment period is long, the sick pheasants are extremely thin even if the sick pheasants are cured, the survival rate is low, and drug residues are easily caused by drug treatment of chemical preparations, so that the sick pheasants cannot be sold in time for a long time, and serious economic loss is caused.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and a preparation method thereof, and solves the problems of poor treatment effect and serious medicine residue of pullorum disease.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 20-30 parts of dandelion, 8-14 parts of purslane, 30-36 parts of Lala seedlings, 30-36 parts of wild chrysanthemum flowers, 18-20 parts of plantain herbs, 8-14 parts of rhizoma atractylodis, 22-28 parts of folium artemisiae argyi, 10-15 parts of houttuynia cordata, 15-22 parts of eucommia ulmoides, 18-24 parts of astragalus membranaceus, 20-24 parts of isatis roots, 15-18 parts of poplar flowers, 18-20 parts of myrobalan, 11-14 parts of andrographis paniculata, 30-35 parts of starch and 80-95 parts of clear water.
A preparation method of a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following specific scheme:
firstly, taking dandelion, purslane, Lala seedlings, wild chrysanthemum flowers, plantain herbs, rhizoma atractylodis, folium artemisiae argyi, houttuynia cordata, eucommia ulmoides, astragalus membranaceus, radix isatidis, poplar flowers, myrobalan and andrographis paniculata in a warehouse, carrying out ultrasonic cleaning on the dandelion, the purslane, the Lala seedlings, the wild chrysanthemum flowers, the plantain herbs, the rhizoma atractylodis, the folium artemisiae argyi, the houttuynia cordata, the eucommia ulmoides, the;
placing the standby raw materials of dandelion, purslane, Lala seedlings, wild chrysanthemum, plantain herb, folium artemisiae argyi, houttuynia cordata, poplar flowers, myrobalan and andrographis paniculata into a steamer, adding clear water, decocting at high temperature and high pressure, stirring the decocted traditional Chinese medicine liquid dregs in the liquid medicine, and filtering by using filter cloth to obtain pure standby liquid medicine;
adding starch into the standby liquid medicine obtained in the step two, stirring and mixing to fully mix the starch and the liquid medicine, and evaporating the mixed liquid medicine with the starch to dryness to obtain first raw material medicinal powder;
step four, dehydrating and drying the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, grinding the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, sieving the ground traditional Chinese medicine powder with a 200-mesh sieve, continuously grinding the traditional Chinese medicine which does not pass through the mesh until the traditional Chinese medicine is completely sieved, and stirring and uniformly mixing the sieved rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis powder to obtain second raw material powder;
and step five, uniformly stirring and mixing the first raw material powder and the second raw material powder to obtain a soluble powder preparation, and quantitatively packaging and warehousing the soluble powder preparation.
Preferably, the dandelion, the purslane, the Lala seedling, the wild chrysanthemum flower, the plantain herb, the rhizoma atractylodis, the folium artemisiae argyi, the houttuynia cordata, the eucommia ulmoides, the astragalus membranaceus, the radix isatidis, the poplar flower, the myrobalan and the andrographis paniculata need to be subjected to pesticide detection before purchase, and the health degree of the plants is analyzed, so that the dandelion, the purslane, the Lala seedling, the wild chrysanthemum flower, the planta.
Preferably, the temperature for drying the raw materials at low temperature in the step one is not more than 25 ℃, the high-pressure environment for boiling the raw materials at high temperature and high pressure in the step two is 85 ℃, the pressure environment is 8Mpa, the temperature is not more than 45 ℃ when starch is added in the step three and is evaporated to dryness, the stirring rod needs to stir variably when the starch is evaporated to dryness, and the stirring speed is forty revolutions per minute.
Preferably, the dosage of the soluble powder preparation is that every 20g of the medicinal powder is mixed with 1000-1100g of clear water.
(III) advantageous effects
The invention provides a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and a preparation method thereof. The method has the following beneficial effects:
the medicine formula of the invention is a pure traditional Chinese medicine formula, is mixed and stirred with water, and is administrated by a water feeding mode or is mixed and administrated by a feed stirring mode, the treatment effect is good, the treatment cost is lower, the treatment medicine can not remain in chicken bodies, the treatment side effect is not caused, the medicine is convenient for the chicken to sell and eat at any time, and the taste of the chicken is not influenced.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
the embodiment of the invention provides a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease, which comprises the following raw materials in parts by weight: 20 parts of dandelion, 8 parts of purslane, 30 parts of Lala seedling, 30 parts of wild chrysanthemum flower, 18 parts of plantain herb, 8 parts of rhizoma atractylodis, 22 parts of folium artemisiae argyi, 10 parts of houttuynia cordata, 15 parts of eucommia ulmoides, 18 parts of astragalus mongholicus, 20 parts of radix isatidis, 15 parts of poplar flower, 18 parts of myrobalan, 11 parts of common andrographis herb, 30 parts of starch and 80 parts of clear water.
A preparation method of a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following specific scheme:
firstly, taking dandelion, purslane, Lala seedlings, wild chrysanthemum flowers, plantain herbs, rhizoma atractylodis, folium artemisiae argyi, houttuynia cordata, eucommia ulmoides, astragalus membranaceus, radix isatidis, poplar flowers, myrobalan and andrographis paniculata in a warehouse, carrying out ultrasonic cleaning on the dandelion, the purslane, the Lala seedlings, the wild chrysanthemum flowers, the plantain herbs, the rhizoma atractylodis, the folium artemisiae argyi, the houttuynia cordata, the eucommia ulmoides, the;
placing the standby raw materials of dandelion, purslane, Lala seedlings, wild chrysanthemum, plantain herb, folium artemisiae argyi, houttuynia cordata, poplar flowers, myrobalan and andrographis paniculata into a steamer, adding clear water, decocting at high temperature and high pressure, stirring the decocted traditional Chinese medicine liquid dregs in the liquid medicine, and filtering by using filter cloth to obtain pure standby liquid medicine;
adding starch into the standby liquid medicine obtained in the step two, stirring and mixing to fully mix the starch and the liquid medicine, and evaporating the mixed liquid medicine with the starch to dryness to obtain first raw material medicinal powder;
step four, dehydrating and drying the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, grinding the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, sieving the ground traditional Chinese medicine powder with a 200-mesh sieve, continuously grinding the traditional Chinese medicine which does not pass through the mesh until the traditional Chinese medicine is completely sieved, and stirring and uniformly mixing the sieved rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis powder to obtain second raw material powder;
and step five, uniformly stirring and mixing the first raw material powder and the second raw material powder to obtain a soluble powder preparation, and quantitatively packaging and warehousing the soluble powder preparation.
Dandelion, purslane, Lala seedlings, wild chrysanthemum, plantain herb, rhizoma atractylodis, folium artemisiae argyi, houttuynia cordata, eucommia, astragalus mongholicus, radix isatidis, poplar flowers, myrobalan and andrographis paniculata need to be subjected to pesticide detection before purchase, and the health degree of the plants is analyzed to reach the national standard and can be used.
The temperature for drying the raw materials at low temperature in the first step is not more than 25 ℃, the high-pressure environment for decocting the raw materials at high temperature and high pressure in the second step is 85 ℃, the pressure environment is 8Mpa, the temperature is not more than 45 ℃ when starch is added in the third step and is evaporated to dryness, the stirring rod needs to stir variably when the starch is evaporated to dryness, and the stirring speed is forty revolutions per minute.
The dosage of the soluble powder preparation is that every 20g of the medicinal powder is mixed with 1000-1100g of clear water.
Example two:
a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 22 parts of dandelion, 10 parts of purslane, 32 parts of larch, 34 parts of wild chrysanthemum flower, 18 parts of plantain herb, 12 parts of rhizoma atractylodis, 24 parts of folium artemisiae argyi, 13 parts of houttuynia cordata, 17 parts of eucommia ulmoides, 20 parts of astragalus mongholicus, 23 parts of radix isatidis, 17 parts of poplar flower, 20 parts of myrobalan, 13 parts of andrographis paniculata, 35 parts of starch and 90 parts of clear water.
Example three:
a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 21 parts of dandelion, 13 parts of purslane, 34 parts of Lala seedling, 32 parts of wild chrysanthemum flower, 19 parts of plantain herb, 12 parts of rhizoma atractylodis, 24 parts of folium artemisiae argyi, 13 parts of houttuynia cordata, 20 parts of eucommia ulmoides, 22 parts of astragalus mongholicus, 22 parts of radix isatidis, 17 parts of poplar flower, 19 parts of myrobalan, 13 parts of andrographis paniculata, 34 parts of starch and 90 parts of clear water.
Example four:
a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 25 parts of dandelion, 12 parts of purslane, 33 parts of larch, 35 parts of wild chrysanthemum flower, 18 parts of plantain herb, 13 parts of rhizoma atractylodis, 24 parts of folium artemisiae argyi, 14 parts of houttuynia cordata, 20 parts of eucommia ulmoides, 23 parts of astragalus mongholicus, 22 parts of radix isatidis, 17 parts of poplar flower, 20 parts of myrobalan, 13 parts of andrographis paniculata, 33 parts of starch and 92 parts of clear water.
Example five:
a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease comprises the following raw materials in parts by weight: 30 parts of dandelion, 14 parts of purslane, 35 parts of Lala seedling, 35 parts of wild chrysanthemum flower, 19 parts of plantain herb, 13 parts of rhizoma atractylodis, 27 parts of folium artemisiae argyi, 14 parts of houttuynia cordata, 20 parts of eucommia ulmoides, 23 parts of astragalus mongholicus, 23 parts of radix isatidis, 17 parts of poplar flower, 19 parts of myrobalan, 13 parts of andrographis paniculata, 34 parts of starch and 95 parts of clear water.
Cure rate Time to cure
Example one 95％ 1.5 days
Example two 93％ 2 days
EXAMPLE III 95％ 2 days
Example four 94％ 1.5 days
EXAMPLE five 96％ 2 days
Traditional medicine therapy 76％ 5-7 days
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. A novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease is characterized in that the formula comprises the following raw materials in parts by weight: 20-30 parts of dandelion, 8-14 parts of purslane, 30-36 parts of Lala seedlings, 30-36 parts of wild chrysanthemum flowers, 18-20 parts of plantain herbs, 8-14 parts of rhizoma atractylodis, 22-28 parts of folium artemisiae argyi, 10-15 parts of houttuynia cordata, 15-22 parts of eucommia ulmoides, 18-24 parts of astragalus membranaceus, 20-24 parts of isatis roots, 15-18 parts of poplar flowers, 18-20 parts of myrobalan, 11-14 parts of andrographis paniculata, 30-35 parts of starch and 80-95 parts of clear water.
2. A preparation method of a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease is characterized by comprising the following specific scheme:
firstly, taking dandelion, purslane, Lala seedlings, wild chrysanthemum flowers, plantain herbs, rhizoma atractylodis, folium artemisiae argyi, houttuynia cordata, eucommia ulmoides, astragalus membranaceus, radix isatidis, poplar flowers, myrobalan and andrographis paniculata in a warehouse, carrying out ultrasonic cleaning on the dandelion, the purslane, the Lala seedlings, the wild chrysanthemum flowers, the plantain herbs, the rhizoma atractylodis, the folium artemisiae argyi, the houttuynia cordata, the eucommia ulmoides, the;
placing the standby raw materials of dandelion, purslane, Lala seedlings, wild chrysanthemum, plantain herb, folium artemisiae argyi, houttuynia cordata, poplar flowers, myrobalan and andrographis paniculata into a steamer, adding clear water, decocting at high temperature and high pressure, stirring the decocted traditional Chinese medicine liquid dregs in the liquid medicine, and filtering by using filter cloth to obtain pure standby liquid medicine;
adding starch into the standby liquid medicine obtained in the step two, stirring and mixing to fully mix the starch and the liquid medicine, and evaporating the mixed liquid medicine with the starch to dryness to obtain first raw material medicinal powder;
step four, dehydrating and drying the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, grinding the rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis, sieving the ground traditional Chinese medicine powder with a 200-mesh sieve, continuously grinding the traditional Chinese medicine which does not pass through the mesh until the traditional Chinese medicine is completely sieved, and stirring and uniformly mixing the sieved rhizoma atractylodis, the eucommia ulmoides, the astragalus mongholicus and the radix isatidis powder to obtain second raw material powder;
and step five, uniformly stirring and mixing the first raw material powder and the second raw material powder to obtain a soluble powder preparation, and quantitatively packaging and warehousing the soluble powder preparation.
3. The novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease according to claim 1, wherein dandelion, purslane, Lala seedling, wild chrysanthemum flower, plantain herb, rhizoma atractylodis, folium artemisiae argyi, houttuynia cordata, eucommia ulmoides, radix astragali, radix isatidis, poplar flower, myrobalan and andrographis paniculata need to be subjected to pesticide detection before purchase, and plant health degree is analyzed, so that the novel pure traditional Chinese medicine composite soluble powder preparation can be used when reaching the national standard.
4. The method for preparing a novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease according to claim 2, wherein the temperature for drying the raw materials at low temperature in the first step is not more than 25 ℃, the high-pressure environment for decocting at high temperature and high pressure in the second step is 85 ℃, the pressure environment is 8Mpa, the temperature for evaporating the raw materials by adding starch in the third step is not more than 45 ℃, the stirring rod needs to be stirred variably when evaporating the raw materials by distillation, and the stirring speed is forty revolutions per minute.
5. The novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease as claimed in claim 1, wherein the dosage of the soluble powder preparation is 1000-1100g of clear water per 20g of powder.
CN202110287479.1A 2021-03-17 2021-03-17 Novel pure traditional Chinese medicine composite soluble powder preparation for preventing and treating pullorum disease and preparation method thereof Pending CN112891430A (en)

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Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
文士元等: "W-H肠炎净的研制与疗效观察", 《中兽医学杂志》 *
计伦: "《鸡病诊治与验方集粹》", 31 October 1997, 经济日报出版社 *
韩照明等: "《农业科技十万问（兽医卫生篇） 鸡鸭鹅病防治问答》", 28 February 1995, 河北科学技术出版社 *

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