CN112891240A

CN112891240A - Composition with cleaning power, foam experience, low tooth wear and low irritation to oral mucosa

Info

Publication number: CN112891240A
Application number: CN202110166296.4A
Authority: CN
Inventors: 付国栋; 彭燕; 辛迪; 蒋建祥; 李圆圆
Original assignee: Nice Zhejiang Technology Co ltd
Current assignee: Nice Lishui Daily Chemical Co ltd; Nice Zhejiang Technology Co ltd; Nice Group Co Ltd
Priority date: 2021-02-05
Filing date: 2021-02-05
Publication date: 2021-06-04
Anticipated expiration: 2041-02-05
Also published as: CN112891240B

Abstract

The invention relates to the field of daily chemicals, and discloses a composition with cleaning power, foam experience, low tooth wear and low oral mucosa irritation.

Description

Composition with cleaning power, foam experience, low tooth wear and low irritation to oral mucosa

Technical Field

The invention relates to the field of daily chemicals, in particular to a composition with cleaning power, foam experience, low tooth wear and low irritation to oral mucosa.

Background

The toothpaste is a necessary oral cleaning and nursing product every day, is a paste substance formed by mixing main raw materials of an abrasive, a foaming agent, a humectant, a thickening agent, an aromatic, water and other additives (containing effective components for improving the oral health condition), and has the basic functions of cleaning the oral cavity, relieving tooth stains, whitening teeth, reducing dental plaque, refreshing breath, refreshing the mouth feel, reducing oral bacteria, maintaining the oral health and the like.

The abrasive is used as the most important raw material in the toothpaste, and the basic function of the toothpaste is mainly achieved by the physical friction of the abrasive (grinding material) on the tooth surface. Therefore, in order to improve the cleaning ability of toothpaste, an abrasive having high physical friction is generally added to toothpaste to improve the cleaning effect of toothpaste on teeth. It is now widely accepted by consumers that the wear of multiple teeth on a toothbrush can be avoided or alleviated by the use of a soft bristle toothbrush. The root cause of the tooth brushing abrasion is not caused by the toothbrush, and the root cause is the continuous grinding of the tooth surface in the long-term tooth brushing process due to the high-hardness, irregular surface and high-friction-value abrasive material in the toothpaste. According to GB/T35832-: the deionized water is adopted to soak the bristle toothbrush for tooth brushing, so that abrasion to the grinding block is avoided; the use of a common toothpaste slurry to soak a bristle toothbrush for brushing teeth can cause significant wear on the abrasive block. Some commercially available toothpastes use abrasives with higher Ra values (such as calcium carbonate, calcium hydrogen phosphate or some high friction silica) as raw materials, which are expected to improve the cleaning power of the product, so some toothpastes have stronger physical friction force and may cause damage to the enamel on the tooth surface, such as scratching. In addition, some consumers often adopt wrong tooth brushing methods such as a 'saw type' method, and the like, so that the tooth brushing method can cause tooth abrasion, defect and decayed tooth after long-term storage, and can also cause negative effects such as pulpitis, periapical periodontitis, osteomyelitis, even tooth fracture and the like seriously.

On the other hand, the foaming agent in the toothpaste can endow the toothpaste with the capability of foaming and cleaning, can reduce the adhesion of tartar and food scraps on the surface of teeth, and can permeate the tartar and the food scraps to disperse the tartar and the food scraps into fine particles to form an emulsified system which is then discharged along with the mouthwash. The sodium dodecyl sulfate (K12) has good foaming property, good compatibility and low price, is always the most main foaming agent in the market, but has stronger irritation to skin and mucosa, stronger degreasing capability and obvious astringent taste after tooth brushing.

Therefore, developing a toothpaste which can ensure low abrasion of enamel and low stimulation of oral mucosa, can ensure effective tooth cleaning and has good foam experience is a development direction of a new generation of toothpaste.

To this end, researchers have attempted a variety of means to address this problem. Chinese patent document CN 109528513A WEAR-FREE WHITE TOOTH PASTE adopts spherical microcrystalline cellulose with particle size ranging from 5-30 μm to reduce friction value of the toothpaste, and simultaneously adds a large amount of phosphate whitening agent to enhance cleaning and whitening effects of the toothpaste. Chinese patent document CN 102429832 novel abrasive composition and toothpaste containing the same, 18-100% of non-thickening microcrystalline cellulose crystalline powder and 0-82% of traditional abrasive are compounded to reduce the abrasion of toothpaste to teeth. Chinese patent document CN 107648062 discloses an amino acid toothpaste without sodium lauryl sulfate and a preparation method thereof, wherein cocoamidopropyl betaine and sodium lauroyl sarcosinate are compounded to replace K12, so that the irritation of oral mucosa is reduced. In chinese patent document CN 110859779 "an oral care toothpaste containing plant fiber abrasive and its preparation method", for special groups of young permanent teeth, young deciduous teeth and old permanent teeth, the characteristic composition of plant fiber particles, xanthan gum and polyethylene glycol 1500 is applied in toothpaste to completely replace traditional abrasive, and reduce the friction value of toothpaste.

However, in the prior art, each solution has respective disadvantages, such as:

chinese patent document CN 109528513 'A toothpast for whitening without abrasion', and Chinese patent document CN 102429832 'novel abrasive composition and toothpastes containing the same', adopt microcrystalline cellulose as abrasive. The microcrystalline cellulose is produced through adding great amount of inorganic acid solution into natural cellulose, boiling to eliminate amorphous part and leave crystalline part, filtering, water washing and ammonia water washing to obtain the rest crystalline part, violent stirring and dispersing, and spray drying to form microcrystalline cellulose powder. As a large amount of chemical reagents such as inorganic acid, ammonia water and the like are added in the production process, a large amount of waste gas and waste liquid are generated in the production process, and certain harm is caused to workshop staff and the ecological environment. And because amorphous acid of the cellulose is etched in the production process, only a large number of cellulose crystallization areas are left to form particles with relatively regular shapes, the particles have a lower RDA value, but because a large number of amorphous areas are etched by the acid, the microcrystalline cellulose reduces the flat strip-shaped and polygonal characteristics of the natural cellulose, and the friction performance and the cleaning effect of the product are reduced.

In chinese patent document CN 110859779 "an oral care toothpaste containing plant fiber abrasive and its preparation method", for special groups with weak enamel, such as young permanent teeth, infant deciduous teeth, and old permanent teeth, the characteristic composition of plant fiber particles, xanthan gum, and polyethylene glycol 1500 is applied in toothpaste to completely replace traditional abrasive, thereby solving the problem of rough appearance of paste generated by plant fiber, and reducing the friction value of toothpaste. However, in practical application, the cost of the all-plant cellulose product is high, and the plant cellulose is independently used as the abrasive, compared with the traditional abrasive toothpaste product, the cleaning power is weak, so that the application object range and the popularization of the product are influenced.

Chinese patent document CN 107648062, an amino acid toothpaste without sodium lauryl sulfate and a preparation method thereof, adopts the compounding of cocamidopropyl betaine and sodium lauroyl sarcosinate to replace K12, thereby reducing the irritation of oral mucosa. However, the foaming characteristics of the cocamidopropyl betaine and the sodium lauroyl sarcosinate are fine and small foams, and the foams are little when the conventional toothpaste is used for brushing teeth, so that the sufficient mouthfeel cannot be brought to consumers, and the subjective feeling of unclean brushing is caused.

Therefore, the prior art means can not meet the market demands of low friction, low irritation to oral mucosa and foam experience while ensuring the cleaning power of the product.

Disclosure of Invention

In order to solve the technical problems, the invention provides a composition with cleaning power, foam experience, low tooth wear and low oral mucosa irritation.

The specific technical scheme of the invention is as follows:

in a first aspect, the present invention provides a composition with cleaning power, a foaming experience, low tooth wear, and low irritation to the oral mucosa comprising: abrasives, sodium lauroyl sarcosinate and cocamidopropyl betaine; the abrasive is a combination of natural cellulose and at least one other abrasive.

The mass ratio of the natural cellulose to other rubbing agents is 1: 1-1: 6; the mass ratio of the sodium lauroyl sarcosine to the cocamidopropyl betaine is 4: 1-1: 1.5; the mass ratio of the total amount of the friction agent to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 10-40: 0.3-1.5; the mass ratio of the natural cellulose to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 1: 0.3-15: 0.3.

The composition capable of being added into the toothpaste is obtained by compounding natural cellulose, a traditional abrasive, sodium lauroyl sarcosinate and cocamidopropyl betaine, can adapt to the conventional toothpaste formula system, and can reduce the tooth abrasion and oral mucosa irritation of the toothpaste while ensuring the cleaning power and tooth brushing foam experience of the toothpaste. Specifically, the method comprises the following steps:

(1) the abrasive in the invention is prepared by compounding natural cellulose and a traditional abrasive. As described in the background art, in the prior art, microcrystalline cellulose is used as an abrasive, but amorphous parts in natural fibers are removed from microcrystalline cellulose in the production process, and only a large amount of cellulose crystalline regions are left to form particles with relatively regular shapes, so that the particles have a low Ra value. The invention can solve the technical problems by combining the natural cellulose and the traditional abrasive according to a specific proportion. Natural cellulose is a long-chain linear high molecular compound, which contains orderly and regular molecular arrangement crystalline regions and irregular molecular arrangement, loose and low-density amorphous regions, and thus has the characteristic of low hardness. The molecular structure characteristics of the cellulose abrasive material enable the cellulose abrasive material to have multifaceted and polygonal properties and flat, banded or twisted appearance characteristics, so that the contact area of the cellulose abrasive material and the tooth surface is greatly increased in the tooth brushing process, and the friction performance is improved. However, due to the characteristic of low hardness, cellulose is relatively soft, so that effective contact and friction cleaning cannot be carried out on the surfaces of teeth during tooth brushing, and therefore, the natural cellulose alone serving as a toothpaste abrasive cannot effectively clean stains on the surfaces of the teeth.

Research shows that the combination of natural cellulose and the traditional abrasive can take effect synergistically: when the natural cellulose and the traditional abrasive are compounded, the contact frequency of the traditional abrasive to the tooth surface can be reduced, and the characteristics of low hardness and strip-shaped distortion of the traditional abrasive can buffer the traditional abrasive with high hardness to grind the tooth surface, so that the abrasion is reduced. The high-hardness traditional rubbing agent can give certain pressure to cellulose during tooth brushing, so that the banded distortion of the cellulose can be better spread, the contact surface with teeth is enlarged, and the polygonal characteristic of the cellulose under certain pressure can be like a plurality of small brushes, so that the teeth can be more effectively cleaned by rubbing the surfaces of the teeth. From the above, the combination of the natural cellulose and the traditional abrasive in the invention is not a simple addition of cleaning power or friction value, but can produce synergistic effect.

It should be noted that the two solutions do not have any combination to achieve significant synergistic effect, and have significant effect only within a specific reasonable proportioning range. Too high a proportion of natural cellulose results in insufficient cleaning power, whereas too high a proportion of conventional abrasives does not significantly reduce the wear on the teeth. A large number of experimental researches show that when the proportion is controlled in the range of the invention, the cleaning power of the product can be ensured, and the tooth abrasion can be reduced.

(2) By compounding the cocamidopropyl betaine and the sodium lauroyl sarcosinate, the invention can effectively reduce the stimulation of the toothpaste to the oral cavity in the tooth brushing process compared with the traditional K12. However, foams generated after the two are simply compounded are small, the foams are easy to defoam during tooth brushing, and the foam quantity during tooth brushing is small in the conventional toothpaste, so that the sufficient mouthfeel can not be brought to consumers, and the subjective feeling of unclean tooth brushing is caused. According to the invention, after the natural cellulose, the cocamidopropyl betaine and the sodium lauroyl sarcosinate are applied to the same toothpaste system, the unique structural performance of the natural cellulose can keep more stable and rich foam, so that the foam experience and subjective feeling during tooth brushing are improved. However, this feature also causes problems in that it is difficult to degas toothpaste during manufacturing and production, resulting in a decrease in production efficiency. After finding the problem, the team of the invention can strictly control the proportion of the natural cellulose, the cocamidopropyl betaine and the sodium lauroyl sarcosine in the composition to simultaneously meet the requirements of foam performance and production process.

In conclusion, the components in the composition are not single functional superposition, but are closely matched with each other and synergized together as a whole, so that the abrasion to teeth during tooth brushing can be effectively reduced, the irritation to oral mucosa can be effectively reduced, and the toothpaste is safer and milder.

Preferably, the mass ratio of the natural cellulose to other rubbing agents is 1: 1-1: 5.

Preferably, the mass ratio of the sodium lauroyl sarcosine to the cocamidopropyl betaine is 4: 1-1: 1.

Preferably, the mass ratio of the total amount of the rubbing agent to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 10-40: 0.45-1.35.

The above proportion is further limited, and the technical effect can be further improved.

Preferably, the other abrasive is one or more of silica, calcium carbonate and calcium hydrogen phosphate.

Preferably, the particle size distribution of the natural cellulose is 15-180 μm, and the median particle size is 50-80 μm. The smaller particle size of the cellulose leads to the reduction of the cleaning ability of the cellulose, the friction value of the product cannot be effectively reduced when other traditional friction agents are compounded, and the situation that the degassing is difficult to occur easily during the production. The large cellulose particle size causes the toothpaste to have a rough appearance, and the toothpaste is easy to have stability problems such as paste-out, and the mouth feel is not refreshing even when the teeth are brushed. Preferably, the natural cellulose is cellulose prepared from one or more of beech, peach, pear and corn stover.

The existing microcrystalline cellulose friction agent needs to add a large amount of chemical reagents such as inorganic acid, ammonia water and the like in the production process, so a large amount of waste gas and waste liquid can be generated in the production process, and certain harm is caused to workshop staff and the ecological environment. The natural cellulose of the invention has rich sources and can be obtained from plants such as beech trees, peach trees, pear trees, corn straws and the like. The process is environment-friendly and safe, and can be obtained by drying, crushing and screening without adding strong acid, strong alkali or other organic solvents for treatment.

In a second aspect, the present invention provides a toothpaste comprising the above composition.

Preferably, the content of the composition in the toothpaste is 10-45 wt%.

Compared with the prior art, the invention has the following technical effects:

(1) the natural cellulose and the traditional abrasive are compounded according to a specific proportion to be used as the abrasive, so that the cleaning power of the toothpaste is ensured, and the abrasion of the toothpaste to teeth is reduced.

(2) According to the invention, through compounding of sodium lauroyl sarcosinate and cocamidopropyl betaine and strictly limiting the proportion of the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine to natural cellulose, the irritation to oral mucosa can be reduced while the tooth brushing foam experience is ensured.

(3) The friction value test and the cleaning force test are respectively carried out by referring to GB/T35832-2018 toothpaste friction value detection method and T/COCIA7-2020 oral care product toothpaste efficacy evaluation and exogenous stain removal effect laboratory evaluation method. Compared with the common toothpaste, the toothpaste adopting the composition has remarkably reduced abrasion to the grinding block, and has statistically significant difference; toothpastes employing the compositions of the present invention maintain the same level or significantly improve cleaning power over conventional toothpastes. Furthermore, the irritation evaluation of the toothpaste containing the composition of the present invention by the Kjeldahl method showed that the irritation grade of the toothpaste could be greatly reduced. Through examination of brushing tests of toothpaste consumers, compared with the common toothpaste, the toothpaste added with the composition provided by the invention has the advantages that the foam is richer and more exquisite during tooth brushing, and unpleasant experiences such as convergence, dryness and the like do not exist in lips or oral cavity.

Detailed Description

General examples

A composition having a combination of cleaning power, lather experience and low dental abrasion with low oral mucosal irritation comprising: abrasives, sodium lauroyl sarcosinate and cocamidopropyl betaine; the abrasive is a combination of natural cellulose and at least one other abrasive.

Preferably, the mass ratio of the natural cellulose to other rubbing agents is 1: 1-1: 5. The mass ratio of the sodium lauroyl sarcosine to the cocamidopropyl betaine is 4: 1-1: 1. The mass ratio of the total amount of the friction agent to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 10-40: 0.45-1.35.

Preferably, the particle size distribution of the natural cellulose is 15-180 μm, and the median particle size is 50-80 μm. The natural cellulose is prepared from one or more of beech tree, peach tree, pear tree and corn straw.

In a second aspect, the invention provides a toothpaste comprising 10 to 45wt% of the above composition.

The present invention will be further described with reference to specific examples and comparative examples.

The mouthfeel experience of brushing teeth. The evaluation method is to find consumers to try to brush and answer questionnaires to evaluate the mouthfeel experience of the toothpaste during tooth brushing.

The Ra value represents the abrasion value. The test is carried out by referring to GB/T35832-2018 toothpaste friction value detection method.

The Δ L value indicates the level of cleaning power. Staining the enamel block in a self-made staining solution, and evaluating the cleaning power by referring to T/COCIA7-2020 laboratory evaluation method for evaluating the effect of removing exogenous stains on toothpaste for oral care products.

While zein value (g/L) indicates an irritation value, surfactants with zein values greater than that of N4 g/L solutions are "strong irritants", and such surfactants are relatively strong in their ability to solubilize zein. (2) The surfactant with the zein value in the solution of N2-4 g/L is low in irritation. (3) Surfactants with zein values less than that of the N2 g/L solution are "non-irritating" and such surfactants have little effect in promoting zein dissolution. The testing method comprises the steps of adding excessive zein into the toothpaste centrifugal liquid, stirring and dissolving, centrifuging, filtering, and taking a filtrate as zein liquid; and then testing the zein value by adopting a Kjeldahl method.

TABLE 1 example/comparative formulation of silica abrasives

Remarking: particle size distribution of the natural cellulose used in table 1: 80% of the particles are 15-180 μm, and the median particle size is 72 μm.

TABLE 2 comparison of Friction values (Ra) of examples/comparative examples of silica abrasives

P value	Example 2	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4
						Example 1	0.8×10^-6	0.4×10^-11	0.3×10^-11	0.9×10^-4	0.7×10^-7
Example 2		0.4×10^-11	0.1×10^-11	0.4×10^-7	0.1×10^-9

Table 3 comparison of cleaning power (Δ L) for example/comparative example silica abrasives

	Example 2	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4
						Example 1	0.2717	0.0001	0.00008	0.0116	0.0867
Example 2		0.0001	0.00007	0.0291	0.2801

Remarking: p value < 0.01, with very significant differences statistically indicated; p value < 0.05, statistically representing significant difference; the P value is more than or equal to 0.05, and no significant difference is shown statistically.

As can be seen from tables 1, 2 and 3 above, examples 1 and 2 of the toothpastes containing natural cellulose and silica abrasive have significantly better cleaning power than the all-natural cellulose toothpastes of comparative examples 1 and 2, more comfortable and moist mouthfeel, and lower Zein value at a non-irritating level. Examples 1-2 compared to the conventional all silica toothpaste of comparative example 4, the use of partial cellulose in place of silica provided improved cleaning power values but statistically no significant differences, reduced abrasion values and statistically very significant differences, and more pleasant and watery mouthfeel performance, with lower Zein values at a non-irritating level. Example 2 compared to the conventional all-silica toothpaste of comparative example 3, with the addition of an additional portion of natural cellulose abrasive, the cleaning power was improved and statistically significantly different, the abrasion value was reduced and statistically significantly different, the mouth feel was more pleasant and moist in appearance, and the Zein value was lower at a non-irritating level. The natural cellulose and silicon dioxide abrasive are added into the traditional toothpaste, so that the friction value of the product can be obviously reduced, the cleaning power of the product is ensured, and the tooth brushing comfort is improved.

Table 4 calcium carbonate abrasives example/comparative example ratios

Remarking: particle size distribution of the natural cellulose used in table 4: 80% of the particles are 15-180 μm, and the median particle size is 72 μm.

TABLE 5 calcium carbonate abrasives example/comparative example Friction value (Ra) comparison

	Example 4	Comparative example 1	Comparative example 2	Comparative example 5	Comparative example 6
						Example 3	0.00039	0.4×10^-10	0.4×10^-10	0.046	0.0000038
Example 4		0.4×10^-11	0.3×10^-11	0.000031	0.10×10^-7

Table 6 calcium carbonate abrasive example/comparative example cleaning power (Δ L) comparison

	Example 4	Comparative example 1	Comparative example 2	Comparative example 5	Comparative example 6
						Example 3	0.8515	0.0099	0.0099	0.0164	0.0373
Example 4		0.0001	0.0001	0.0007	0.0035

As can be seen from tables 4-6 above, examples 3 and 4 of the toothpastes containing natural cellulose and calcium carbonate have significantly better cleaning power than the all-natural cellulose toothpastes of comparative examples 1 and 2, more comfortable and moist mouthfeel, and lower Zein value at a low irritation level. Examples 3, 4, replacing calcium carbonate with a portion of natural cellulose, improved cleaning and statistically significant differences, reduced abrasion values and statistically significant differences, and more pleasant and watery mouthfeel performance, lower Zein values at low levels of irritation, compared to the conventional all calcium carbonate toothpaste of comparative example 6. Example 4, compared to the conventional all calcium carbonate toothpaste of comparative example 5, with the addition of part of the natural cellulose abrasive, the cleaning power was improved and statistically significantly different, the abrasion value was reduced and statistically significantly different, and the mouth feel was more pleasant and moist in appearance, and the Zein value was lower at a low level of irritation. The natural cellulose and calcium carbonate are added into the traditional toothpaste, so that the friction value of the product can be obviously reduced, the cleaning power of the product is ensured, and the tooth brushing comfort is improved.

Through comparison and analysis of the data of the examples 1-4 and the comparative examples 1-6, it can be seen that the toothpaste adopting the natural cellulose and the calcium carbonate can ensure the cleaning power and obviously reduce the tooth abrasion, and ensure the low irritation and the foaming experience of the product.

The composition is not simple in raw material proportioning, but scientific in proportioning by exploring the characteristics among the raw material components in the composition, so as to generate a synergistic effect. Further examples and comparative examples are provided below to further illustrate the correlation between the compositions of the present invention.

TABLE 7 interaction between the Components in the compositions

Remarking: particle size distribution of the natural cellulose used in table 7: 80% of the particles are 15-180 μm, and the median particle size is 72 μm.

Comparing example 2 and comparative example 7, it can be seen that S12: too high content of CAB in CAB can cause dense and non-refreshing bubbles in air bubble tooth brushing, and the main reason is that CAB has fine and stable foam.

Comparing example 2 and comparative example 8, it can be seen that CAB: the proportion of S12 in the composition is satisfactory, but the ratio of natural cellulose: too low ratio (S12/CAB) in (S12/CAB) can result in sparse brushing foam and unsatisfactory paste dispersion.

TABLE 8 interaction between Components in the compositions

Remarking: particle size distribution of the natural cellulose used in table 8: 80% of the particles are 15-180 μm, and the median particle size is 72 μm.

Comparing examples 5 and 6 with comparative examples 10 to 13, it can be seen that too high a natural cellulose ratio results in a significant reduction in cleaning power, while too low a natural cellulose ratio is not effective in reducing tooth wear. In addition, in comparison with comparative examples 10 to 13, too high a ratio of natural cellulose itself in the composition also resulted in difficulty in degassing the paste and a pasty feeling upon brushing.

TABLE 9 comparison of friction values (Ra) of examples/comparative examples

	Comparative example 10	Comparative example 11	Comparative example 12	Comparative example 13
					Example 5	0.1×10^-8	0.0009	0.4×10^-10	0.5×10^-7
Example 6	0.6×10^-12	0.00002	0.1×10^-14	0.7×10^-8

TABLE 10 comparison of cleaning power (. DELTA.L) of examples/comparative examples

	Comparative example 10	Comparative example 11	Comparative example 12	Comparative example 13
					Example 5	0.6900	0.0007	0.0004	0.7332
Example 6	0.4576	0.0008	0.0005	0.4888

Comparing example 6 with comparative example 9, it can be seen that the natural cellulose: too high ratio of (S12/CAB) in (S12/CAB) causes the problem of difficult degassing, and influences the product quality, the production process and the energy efficiency.

Combining the data of the above examples and comparative examples, it can be seen that as long as the ratio of each substance in the composition is strictly limited within the scope of the present invention, the toothpaste can reduce the abrasion of the toothpaste to the teeth and the irritation of the oral mucosa while ensuring the cleaning power of the toothpaste and the brushing foam experience, otherwise, the effects are discounted to different degrees.

The raw materials and equipment used in the invention are common raw materials and equipment in the field if not specified; the methods used in the present invention are conventional in the art unless otherwise specified.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and all simple modifications, alterations and equivalents of the above embodiments according to the technical spirit of the present invention are still within the protection scope of the technical solution of the present invention.

Claims

1. A composition having a combination of cleaning power, lather experience and low dental abrasion with low oral mucosal irritation comprising: abrasives, sodium lauroyl sarcosinate and cocamidopropyl betaine; the abrasive is a combination of natural cellulose and at least one other abrasive;

the mass ratio of the natural cellulose to other rubbing agents is 1: 1-1: 6;

the mass ratio of the sodium lauroyl sarcosinate to the cocamidopropyl betaine is 4: 1-1: 1.5;

the mass ratio of the total amount of the friction agent to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 10-40: 0.3-1.5;

the mass ratio of the natural cellulose to the total amount of sodium lauroyl sarcosinate and cocamidopropyl betaine is 1: 0.3-15: 0.3.

2. The composition of claim 1, wherein: the mass ratio of the natural cellulose to other rubbing agents is 1: 1-1: 5.

3. The composition of claim 1, wherein: the mass ratio of the sodium lauroyl sarcosine to the cocamidopropyl betaine is 4: 1-1: 1.

4. The composition of claim 1, wherein: the mass ratio of the total amount of the friction agent to the total amount of the sodium lauroyl sarcosinate and the cocamidopropyl betaine is 10-40: 0.45-1.35.

5. The composition of claim 1, wherein: the other abrasive is one or more of silicon dioxide, calcium carbonate and calcium hydrophosphate.

6. The composition of claim 1, wherein: the particle size distribution of the natural cellulose is 15-180 mu m, and the median particle size is 50-80 mu m.

7. The composition of claim 6, wherein: the natural cellulose is prepared from one or more of beech tree, peach tree, pear tree and corn straw.

8. A toothpaste, characterized in that: comprising a composition according to any one of claims 1 to 7.

9. The toothpaste according to claim 8, wherein: the content of the composition in the toothpaste is 10-45 wt%.