CN112891233A - Synthetic preparation and preparation method and application thereof - Google Patents
Synthetic preparation and preparation method and application thereof Download PDFInfo
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- CN112891233A CN112891233A CN202110251135.5A CN202110251135A CN112891233A CN 112891233 A CN112891233 A CN 112891233A CN 202110251135 A CN202110251135 A CN 202110251135A CN 112891233 A CN112891233 A CN 112891233A
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- radium stone
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- purple sand
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- 229910052705 radium Inorganic materials 0.000 claims abstract description 54
- HCWPIIXVSYCSAN-UHFFFAOYSA-N radium atom Chemical compound [Ra] HCWPIIXVSYCSAN-UHFFFAOYSA-N 0.000 claims abstract description 54
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- 239000004576 sand Substances 0.000 claims abstract description 33
- 238000010304 firing Methods 0.000 claims abstract description 24
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- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 17
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 17
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 17
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 17
- 238000000855 fermentation Methods 0.000 claims abstract description 17
- 230000004151 fermentation Effects 0.000 claims abstract description 17
- 239000002904 solvent Substances 0.000 claims abstract description 13
- 239000012535 impurity Substances 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 40
- 238000002156 mixing Methods 0.000 claims description 28
- 238000001354 calcination Methods 0.000 claims description 26
- 239000000203 mixture Substances 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- 238000001816 cooling Methods 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 15
- 238000009472 formulation Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
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- -1 oxygen ion Chemical class 0.000 description 3
- 239000000941 radioactive substance Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- FMGSKLZLMKYGDP-UHFFFAOYSA-N Dehydroepiandrosterone Natural products C1C(O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CC=C21 FMGSKLZLMKYGDP-UHFFFAOYSA-N 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
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- 239000011575 calcium Substances 0.000 description 2
- FMGSKLZLMKYGDP-USOAJAOKSA-N dehydroepiandrosterone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 FMGSKLZLMKYGDP-USOAJAOKSA-N 0.000 description 2
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- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
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- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- DWCSNWXARWMZTG-UHFFFAOYSA-N Trigonegenin A Natural products CC1C(C2(CCC3C4(C)CCC(O)C=C4CCC3C2C2)C)C2OC11CCC(C)CO1 DWCSNWXARWMZTG-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
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- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
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- 239000003153 chemical reaction reagent Substances 0.000 description 1
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
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- WQLVFSAGQJTQCK-VKROHFNGSA-N diosgenin Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CC[C@H](O)CC4=CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 WQLVFSAGQJTQCK-VKROHFNGSA-N 0.000 description 1
- WQLVFSAGQJTQCK-UHFFFAOYSA-N diosgenin Natural products CC1C(C2(CCC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 WQLVFSAGQJTQCK-UHFFFAOYSA-N 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
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- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
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- 230000003020 moisturizing effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
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- 238000005502 peroxidation Methods 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
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- 230000002285 radioactive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
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- 231100000274 skin absorption Toxicity 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of preparation synthesis and application, and discloses a synthetic preparation and a preparation method and application thereof. The preparation method comprises the steps of carrying out kiln firing on radium stone and purple sand according to the optimal proportion, and then combining with Chinese yam peel fermentation to obtain a finished product. The product can be mixed into skin care product to increase skin penetrability and nutrient absorption, and release far infrared and negative oxygen ion to achieve antioxidant effect and improve skin care function and effect. The radium stone is crushed, kiln-burned and cooled for multiple times during preparation, other impurities contained in the radium stone are removed, the radioactivity of the radium stone is reduced by using high-temperature kiln burning, the safety is improved, and the radium stone is high in efficiency. When a finished product is obtained, the yam skins, the solvent and the like are selected for fermentation, so that the yam skins and the solvent can be more fully reacted and mixed with the radium stone standby object, the contact area of the radium stone standby object is increased, meanwhile, yam polysaccharides and dioscin active ingredients rich in the yam skins are fully fused, and the storage life is prolonged.
Description
Technical Field
The invention belongs to the technical field of preparation synthesis and application, and particularly relates to a synthetic preparation and a preparation method and application thereof.
Background
Generally, in purple sand, the content of iron oxide can reach about 8 percent, the content of trace elements such as silicon, manganese and the like is higher, and other elements such as calcium, magnesium, sodium, potassium and the like are also important elements required by human bodies. The inner container of the purple sand cooker is a mineralized environment which is beneficial to human bodies to absorb important elements like medical stone. The general purple sand inner container is sanitary, nontoxic and easy to clean, harmful metal ions are prevented from being taken in, and the original taste and flavor of stewed food are not lost.
The negative ion generation amount of the radium stone reaches 1150-1650ions, and belongs to the currently known high natural mineral stone.
Radium stone refers to natural ore containing radium element. Radium is a chemical element. The chemical symbol Ra, the atomic number 88, the atomic weight 226.0254, belong to the group IIA of the periodic system, are members of alkaline earth metals and are naturally radioactive elements.
The function of radium ore series products: radium is called "Quanling" of hot spring, which is very rare in the world and in ancient and modern times. Its negative ion generation quantity is very high, can play the role of purifying air, electrolyzing water and reducing water molecular beam, at the same time, it can continuously release radium gas, and has unique and peculiar effect in the medical health-care field.
Radium stone is rich in radioactive substances, and must be fired for many times at different temperatures to reduce radioactivity within an effective safety range of a human body (ionizing radiation coefficient is less than 0.2usv/h and micro-schrifer/h). In the prior art, the safe use and related application of the radium stone have the problems of complex operation process, low utilization rate of finished products prepared by utilizing the radium stone, low effective rate after being mixed in skin care products and the like.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a synthetic preparation and a preparation method and application thereof.
The technical scheme adopted by the invention is as follows: a method of making a synthetic formulation, the method comprising the steps of:
A. primary calcination: selecting radium stone and purple sand according to a corresponding proportion, mixing, kiln-firing and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained standby material A, mixing purple sand, kiln firing and cooling to obtain a standby material B;
C. and (3) third calcination: crushing the obtained spare material B, mixing purple sand, kiln firing and cooling to obtain a spare material C;
D. obtaining a finished product: selecting the Chinese yam skins according to the corresponding proportion, mixing the Chinese yam skins with the standby C and the solvent for fermentation, sterilizing, filtering residues, adding a flocculating agent, stirring, centrifuging, and removing impurities to obtain a finished product.
The invention provides a preparation method of a synthetic preparation, and the preparation method comprises the steps of carrying out kiln firing on radium stone and purple sand according to the optimal proportion, and then combining with Chinese yam skins for fermentation to obtain a finished product. The product can increase skin penetrability and nutrient absorption after being mixed into skin care product, and can achieve corresponding antioxidant effect by releasing far infrared and negative oxygen ion, thereby improving function and effect of maintenance. The preparation method of the finished product is used for crushing, kiln burning and cooling the radium stone for many times, so that other impurities contained in the radium stone are removed, and then the radioactivity of the radium stone is reduced by using high-temperature kiln burning, so that the safety is improved, and the efficiency is high. When the synthetic preparation is prepared to obtain a finished product, the yam peel and the solvent are selected for mixed fermentation, the yam peel fermentation liquor can be used for fully reacting and mixing with the radium stone standby product, the contact area of the radium stone standby product is increased, meanwhile, the yam polysaccharides and the dioscin components rich in the yam peel are fully fused, and the storage period is prolonged.
Preferably, in the step A, when the radium stone and the purple sand are mixed, the mass ratio of the radium stone to the purple sand is 1-2: 1-2;
the kiln firing temperature is 700-750 ℃;
the kiln burning time is 2-3 hours.
Preferably, in the step B, the particle size of the spare material A after being crushed is 800-1000 meshes;
the mass ratio of the crushed standby material A to the mixed purple sand is 1-2: 5-10;
step B, during the secondary calcination, the kiln temperature is 900-;
the kiln burning time is 2-3 hours.
Preferably, in the step C, the particle size of the spare material B after being crushed is 800-1000 meshes;
the mass ratio of the crushed standby material B to the mixed purple sand is 1-2: 5-10;
step C, when the third calcination is carried out, the kiln temperature is 900-;
the kiln burning time is 2-3 hours.
The preparation method of the finished product is used for crushing, kiln burning and cooling the radium stone for many times, so that other impurities contained in the radium stone are removed, and then the radioactivity of the radium stone is reduced by using high-temperature kiln burning, so that the safety is improved, and the high efficiency is achieved.
Preferably, in the step D, the solvent is negative potential water.
Negative potential water is ionized water in which water molecules are negatively charged and become ionic, and since ions are far more unstable than molecules, water is activated. Benefits of negative potential water: 1. the pH value of the negative potential water is alkaline, which is beneficial to balancing the blood lactic acid generated by the human body due to excessive fatigue (spirit and physical strength) and enables people to recover from fatigue as soon as possible. 2. The negative potential water has high content of ionized calcium, which is a health element beneficial to human body. 3. The negative potential water has high solubility and strong permeability, and has certain emulsifying capacity on grease, so that the negative potential water is favorable for relieving symptoms such as hyperlipidemia, hypercholesterolemia, high blood viscosity and the like caused by high-protein and high-calorie diet. 4. More importantly, the water with low potential or negative potential (the ORP is from 0 to minus 200mv), which can balance the peroxidation free radical generated in the metabolism process of human body, improve the activity of SOD and eliminate the degradation product Malondialdehyde (MDA) of lipid peroxidation, so that the cells are always full of activity and keep healthy, and the negative ions can help the human body to eliminate harmful cyanide, chromate, nitrite, heavy metal and inert metal, so that the water with negative potential becomes drinking water with specific health care function due to the factors and the comprehensive effect. The negative potential water is selected in the method, and the negative potential water is used for matching partial positive electricity in the radium stone standby object, so that the unloading purpose is achieved.
Preferably, in the step D, the mass ratio of the yam skins and the standby substance C to the solvent is 10-50:1-3: 1-3.
Preferably, in the step D, the fermentation temperature is 30-35 ℃;
the fermentation time is 20-30 days; preferably 21 days.
The rhizoma Dioscoreae peel contains dioscin. Dioscin is known as natural DHEA (dehydroepiandrosterone). The ingredients are beneficial to synthesizing various hormones in vivo, are called as hormones, can promote the metabolism of skin epidermal cells, improve the moisturizing function of skin and have certain help effect on improving the physique. The rhizoma Dioscoreae polysaccharide is the main active ingredient of rhizoma Dioscoreae, and has effects of regulating immunity, reducing blood sugar, resisting oxidation, resisting aging, and resisting tumor.
Preferably, in step D, the flocculant comprises a microbial flocculant comprising one or more of a glycoprotein, a mucopolysaccharide, a protein, and cellulose;
the volume ratio of the total volume of the Chinese yam skins, the standby product C and the solvent to the volume of the flocculating agent is 10-50:1-3: 1-3.
A synthetic formulation obtainable by the method of making a synthetic formulation according to any one of claims 1 to 8.
The synthetic preparation has high safety and can promote skin absorption.
Use of a synthetic formulation as defined in claim 9 in a skin care product.
The synthetic preparation can be mixed into skin care products to effectively improve the absorption rate of the finished products.
The invention has the beneficial effects that:
the invention provides a preparation method of a synthetic preparation, which is a finished product obtained by kiln firing radium stone and purple sand according to the optimal proportion and then combining with Chinese yam skins for fermentation. The product can increase skin penetrability and nutrient absorption after being mixed into skin care product, and can achieve corresponding antioxidant effect by releasing far infrared and negative oxygen ion, thereby improving function and effect of maintenance. The preparation method of the finished product is used for crushing, kiln burning and cooling the radium stone for many times, so that other impurities contained in the radium stone are removed, and then the radioactivity of the radium stone is reduced by using high-temperature kiln burning, so that the safety is improved, and the efficiency is high. When the synthetic preparation is prepared to obtain a finished product, the yam peel and the solvent are selected for mixed fermentation, the yam peel fermentation liquor can be used for fully reacting and mixing with the radium stone standby product, the contact area of the radium stone standby product is increased, meanwhile, yam polysaccharide dioscin ingredients rich in the yam peel are fully fused, and the storage period is prolonged.
Negative potential water is selected, and partial positive electricity in the radium stone standby object is matched by using the negative potential water, so that the unloading purpose is achieved.
Detailed Description
The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. The examples were carried out under the conventional conditions, unless otherwise specified. The reagents used are all conventional products which are commercially available.
Example 1:
a method of preparing a synthetic formulation comprising the steps of:
A. primary calcination: selecting 1000 g of radium stone and 1000 g of purple sand according to a corresponding proportion, mixing, performing kiln firing at 700 ℃ for 2 hours, and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained spare A, screening the crushed spare A by using a 800-mesh screen, mixing purple sand with a corresponding proportion, kiln-firing the mixture for 2 hours at 900 ℃, and cooling the mixture to obtain a spare B;
C. and (3) third calcination: crushing the obtained spare material B, screening the crushed spare material B by using a 800-mesh screen, mixing purple sand in a corresponding proportion, kiln-firing the mixture for 2 hours at 900 ℃, and cooling the mixture to obtain a spare material C;
D. obtaining a finished product: selecting Chinese yam peel according to a corresponding proportion, mixing with the standby substance C and negative potential water, fermenting for 20 days at 30 ℃, sterilizing, filtering residues, adding glycoprotein, stirring, centrifuging, and removing impurities to obtain a finished product.
In the above technical solution, the radioactive substance is removed by calcining the radium stone three times, and in the actual operation process, the number of times of calcining the radium stone is not limited to the above three times, because the number of times of calcining the radium stone is required to reach the national standard for removing the radioactive substance by calcining is not limited to the above three times.
In the step D, when the finished product is obtained, a low-speed stirring mode is recommended, the mixing speed is 35-40 revolutions per minute, the stirring can be carried out for 1 hour or more, and the finished product is homogeneous.
For the above sterilization, pasteurization or the like may be employed.
Example 2:
a method of preparing a synthetic formulation comprising the steps of:
A. primary calcination: selecting 1000 g of radium stone and 1000 g of purple sand according to a corresponding proportion, mixing, performing kiln firing at 750 ℃ for 3 hours, and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained standby material A, screening the crushed standby material A by a 1000-mesh screen, mixing purple sand with corresponding proportion, kiln-firing the mixture for 3 hours at 1000 ℃, and cooling the mixture to obtain a standby material B;
C. and (3) third calcination: crushing the obtained spare material B, screening the crushed spare material B by a 1000-mesh screen, mixing purple sand with corresponding proportion, kiln-firing the mixture for 3 hours at 1000 ℃, and cooling the mixture to obtain a spare material C;
D. obtaining a finished product: selecting the Chinese yam skins according to the corresponding proportion, mixing the Chinese yam skins with the spare substance C and the negative potential water, fermenting for 30 days at 35 ℃, sterilizing, filtering residues, adding mucopolysaccharide, stirring, centrifuging, and removing impurities to obtain a finished product.
Example 3:
a method of preparing a synthetic formulation comprising the steps of:
A. primary calcination: selecting 1000 g of radium stone and 1000 g of purple sand according to a corresponding proportion, mixing, performing kiln firing at 700 ℃ for 2 hours, and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained spare A, screening the crushed spare A by using a 800-mesh screen, mixing purple sand with a corresponding proportion, kiln-firing the mixture for 2 hours at 900 ℃, and cooling the mixture to obtain a spare B;
C. and (3) third calcination: crushing the obtained spare material B, screening the crushed spare material B by using a 800-mesh screen, mixing purple sand in a corresponding proportion, kiln-firing the mixture for 2 hours at 900 ℃, and cooling the mixture to obtain a spare material C;
D. obtaining a finished product: selecting the Chinese yam skins according to the corresponding proportion, mixing the Chinese yam skins with the standby substance C and the negative potential water, fermenting for 21 days at the temperature of 30 ℃, sterilizing, filtering residues, adding protein, stirring, centrifuging, and removing impurities to obtain a finished product.
Example 4:
a method of preparing a synthetic formulation comprising the steps of:
A. primary calcination: selecting 1000 g of radium stone and 1000 g of purple sand according to a corresponding proportion, mixing, performing kiln firing at 750 ℃ for 3 hours, and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained standby material A, screening the crushed standby material A by a 1000-mesh screen, mixing purple sand with corresponding proportion, kiln-firing the mixture for 3 hours at 1000 ℃, and cooling the mixture to obtain a standby material B;
C. and (3) third calcination: crushing the obtained spare material B, screening the crushed spare material B by a 1000-mesh screen, mixing purple sand with corresponding proportion, kiln-firing the mixture for 3 hours at 1000 ℃, and cooling the mixture to obtain a spare material C;
D. obtaining a finished product: selecting the Chinese yam skins according to the corresponding proportion, mixing the Chinese yam skins with the spare substance C and the negative potential water, fermenting for 21 days at 35 ℃, sterilizing, filtering residues, adding cellulose, stirring, centrifuging, and removing impurities to obtain a finished product.
The finished products prepared by the embodiments can be added into skin care products such as beauty cream, emulsion, essence, facial mask and the like for application.
The invention provides a preparation method of a synthetic preparation, which is a finished product obtained by kiln firing radium stone and purple sand according to the optimal proportion and then combining with Chinese yam skins for fermentation. The product can increase skin penetrability and nutrient absorption after being mixed into skin care product, and can achieve corresponding antioxidant effect by releasing far infrared and negative oxygen ion, thereby improving function and effect of maintenance. The preparation method of the finished product is used for crushing, kiln burning and cooling the radium stone for many times, so that other impurities contained in the radium stone are removed, and then the radioactivity of the radium stone is reduced by using high-temperature kiln burning, so that the safety is improved, and the efficiency is high. When the synthetic preparation is prepared to obtain a finished product, the yam peel and the solvent are selected for mixed fermentation, the yam peel fermentation liquor can be used for fully reacting and mixing with the radium stone standby product, the contact area of the radium stone standby product is increased, meanwhile, the yam polysaccharide and the diosgenin components rich in the yam peel are fully fused, and the storage life is prolonged.
Negative potential water is selected, and partial positive electricity in the radium stone standby object is matched by using the negative potential water, so that the unloading purpose is achieved.
While particular embodiments of the present invention have been illustrated and described, it will be appreciated that the present invention is not limited to the above-described alternative embodiments, and that various other forms of product may be devised by anyone in light of the present invention. The foregoing detailed description should not be construed as limiting the scope of the invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the foregoing embodiments, or that equivalent substitutions may be made to some or all of the technical features thereof, without departing from the spirit and scope of the invention, and that these modifications or substitutions may not substantially depart from the essence of the corresponding technical solutions.
Claims (10)
1. A method of making a synthetic formulation, comprising the steps of:
A. primary calcination: selecting radium stone and purple sand according to a corresponding proportion, mixing, kiln-firing and cooling to obtain a standby material A;
B. secondary calcination: crushing the obtained standby material A, mixing purple sand, kiln firing and cooling to obtain a standby material B;
C. and (3) third calcination: crushing the obtained spare material B, mixing purple sand, kiln firing and cooling to obtain a spare material C;
D. obtaining a finished product: selecting the Chinese yam skins according to the corresponding proportion, mixing the Chinese yam skins with the standby C and the solvent for fermentation, sterilizing, filtering residues, adding a flocculating agent, stirring, centrifuging, and removing impurities to obtain a finished product.
2. The method for preparing a synthetic preparation according to claim 1, wherein in the step A, when the radium stone and the purple sand are mixed, the mass ratio of the radium stone to the purple sand is 1-2: 1-2;
the kiln firing temperature is 700-750 ℃;
the kiln burning time is 2-3 hours.
3. The method as claimed in claim 1, wherein in step B, the particle size of the material A is 800-1000 mesh after being crushed;
the mass ratio of the crushed standby material A to the mixed purple sand is 1-2: 5-10;
step B, during the secondary calcination, the kiln temperature is 900-;
the kiln burning time is 2-3 hours.
4. The method as claimed in claim 1, wherein in step C, the particle size of the material B is 800-1000 mesh after being crushed;
the mass ratio of the crushed standby material B to the mixed purple sand is 1-2: 5-10;
step C, when the third calcination is carried out, the kiln temperature is 900-;
the kiln burning time is 2-3 hours.
5. The method of claim 1, wherein in step D, the solvent is water with negative potential.
6. The method for preparing a synthetic preparation according to claim 1, wherein in the step D, the mass ratio of the yam bark, the standby product C and the solvent is 10-50:1-3: 1-3.
7. The method for preparing a synthetic formulation according to claim 1, wherein in step D, the fermentation temperature is 30-35 degrees celsius;
the fermentation time is 20-30 days; preferably 21 days.
8. The method of claim 1, wherein in step D, the flocculant comprises a microbial flocculant, the microbial flocculant comprising one or more of a glycoprotein, a mucopolysaccharide, a protein, and cellulose;
the volume ratio of the total volume of the Chinese yam skins, the standby product C and the solvent to the volume of the flocculating agent is 10-50:1-3: 1-3.
9. A synthetic preparation obtained by the method for producing a synthetic preparation according to any one of claims 1 to 8.
10. Use of a synthetic preparation, characterized in that use of a finished synthetic preparation according to claim 9 in a skin care product is used.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106879904A (en) * | 2017-03-21 | 2017-06-23 | 河南洛阳红牡丹产业研发有限公司 | A kind of preparation method of yam drink |
| CN107469027A (en) * | 2017-07-26 | 2017-12-15 | 宁波保税区攀峒信息科技有限公司 | A kind of preparation for alleviating skin symptom |
| CN107519317A (en) * | 2017-08-29 | 2017-12-29 | 宁波保税区攀峒信息科技有限公司 | A kind of Chinese herbal and crude drugs preparations for alleviating skin symptom |
| CN107986749A (en) * | 2017-11-28 | 2018-05-04 | 山西晋明堂文化科技有限公司 | A kind of boccaro rock mud herbal cuisine kettle and preparation method thereof |
| CN110694054A (en) * | 2019-10-25 | 2020-01-17 | 张赞红 | Mineral concentrate film for promoting hormone secretion, metabolism and circulation and preparation method thereof |
-
2021
- 2021-03-08 CN CN202110251135.5A patent/CN112891233A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106879904A (en) * | 2017-03-21 | 2017-06-23 | 河南洛阳红牡丹产业研发有限公司 | A kind of preparation method of yam drink |
| CN107469027A (en) * | 2017-07-26 | 2017-12-15 | 宁波保税区攀峒信息科技有限公司 | A kind of preparation for alleviating skin symptom |
| CN107519317A (en) * | 2017-08-29 | 2017-12-29 | 宁波保税区攀峒信息科技有限公司 | A kind of Chinese herbal and crude drugs preparations for alleviating skin symptom |
| CN107986749A (en) * | 2017-11-28 | 2018-05-04 | 山西晋明堂文化科技有限公司 | A kind of boccaro rock mud herbal cuisine kettle and preparation method thereof |
| CN110694054A (en) * | 2019-10-25 | 2020-01-17 | 张赞红 | Mineral concentrate film for promoting hormone secretion, metabolism and circulation and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 中华人民共和国卫生部: "《化妆品安全技术规范》", 1 December 2016 * |
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