CN112870330A - Wet plaster for treating acute exudative dermatitis and eczema and preparation method thereof - Google Patents
Wet plaster for treating acute exudative dermatitis and eczema and preparation method thereof Download PDFInfo
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- 230000001154 acute effect Effects 0.000 title claims abstract description 27
- 206010012435 Dermatitis and eczema Diseases 0.000 title claims abstract description 19
- 239000011505 plaster Substances 0.000 title claims abstract description 10
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000004744 fabric Substances 0.000 claims abstract description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000003906 humectant Substances 0.000 claims abstract description 11
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 10
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229940041616 menthol Drugs 0.000 claims abstract description 10
- 241000237536 Mytilus edulis Species 0.000 claims abstract description 8
- 239000012528 membrane Substances 0.000 claims abstract description 8
- 235000020638 mussel Nutrition 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 240000007267 Stephania hernandifolia Species 0.000 claims abstract description 7
- 229960004063 propylene glycol Drugs 0.000 claims abstract description 7
- 239000001509 sodium citrate Substances 0.000 claims abstract description 6
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 6
- 235000011187 glycerol Nutrition 0.000 claims abstract description 5
- 239000008213 purified water Substances 0.000 claims abstract description 5
- 239000000243 solution Substances 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 20
- 201000004624 Dermatitis Diseases 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 16
- 208000010668 atopic eczema Diseases 0.000 claims description 8
- 239000002994 raw material Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 239000011259 mixed solution Substances 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 4
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims description 3
- 239000007853 buffer solution Substances 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 230000003750 conditioning effect Effects 0.000 claims description 3
- 238000007731 hot pressing Methods 0.000 claims description 3
- 239000004745 nonwoven fabric Substances 0.000 claims description 3
- 235000013772 propylene glycol Nutrition 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 239000003607 modifier Substances 0.000 claims description 2
- 239000004909 Moisturizer Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 208000003251 Pruritus Diseases 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 239000003755 preservative agent Substances 0.000 abstract description 3
- 230000002335 preservative effect Effects 0.000 abstract description 3
- 230000008961 swelling Effects 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000037380 skin damage Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 4
- 230000009885 systemic effect Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 2
- 238000001126 phototherapy Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 229930105110 Cyclosporin A Natural products 0.000 description 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 description 1
- 108010036949 Cyclosporine Proteins 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 description 1
- 241000029486 Stephania sinica Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 229960002170 azathioprine Drugs 0.000 description 1
- LMEKQMALGUDUQG-UHFFFAOYSA-N azathioprine Chemical compound CN1C=NC([N+]([O-])=O)=C1SC1=NC=NC2=C1NC=N2 LMEKQMALGUDUQG-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 238000001794 hormone therapy Methods 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
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Abstract
The invention provides a wet application for treating acute exudative dermatitis and eczema and a preparation method thereof, the wet application comprises carrier membrane cloth, an astringent, a humectant, a skin feeling regulator, a pH regulator, Kaipristal, a stephania japonica extract, a mussel extract, menthol, 1, 2, 3-glycerol (glycerin), 1, 2-propylene glycol, sodium citrate and purified water, and the wet application is mainly used for treating and relieving symptoms of skin damage, exudation, redness and swelling, pruritus and the like of a patient suffering from acute exudative dermatitis and eczema. The wet application can quickly eliminate pruritus, astringe damaged skin, prevent the damaged skin from further expanding, adjust the skin feeling and the moisture degree of the diseased skin part, moisten and protect the damaged skin, provide a cool and comfortable repair environment for the skin, is harmless to human health and has good safety. Meanwhile, the wet plaster is convenient to use, free of preservative addition, free of side effects, high in safety and simple in production process.
Description
Technical Field
The invention relates to the technical field of skin protection treatment, in particular to a wet application for treating acute exudative dermatitis and eczema and a preparation method thereof.
Background
Dermatitis eczema is the most common skin disease in clinical dermatology. The infant frequently attacks the disease, part of patients continue to live for a long time, the life quality of the patients can be seriously influenced by chronic recurrent eczematous rash, severe pruritus, sleep loss, diet restriction and psychological and social influence, and meanwhile, huge social and economic burden is brought to the patients and families. Particularly, acute exudative dermatitis eczema is often challenging to treat, and since many systemic therapeutic drugs, such as glucocorticoid, cyclosporine A, azathioprine, methotrexate and the like, are limited due to large side effects and cannot be widely applied, systemic phototherapy is also limited by age, and particularly, the systemic phototherapy is prohibited for infants under 6 years old, so that the treatment difficulty is increased. Clinically, gel, spray and aqueous medicines are also used to cooperate with hormone therapy. When the water aqua is used, after the water aqua is usually sprayed, the preservative film is wound to prevent the medicine from being evaporated too fast, the operation is complicated, the effect is not ideal, and simultaneously, the water aqua can not be suitable for all patients, particularly for infant patients.
On the basis, the wet application for the acute exudation period is researched and developed, has the effects of astringing damaged skin and moisturizing, and is simple to operate, safe, convenient to carry and capable of being used anytime and anywhere. The traditional Chinese medicine composition has the advantages of quick response, remarkable control of pruritus, quick elimination of red swelling, no preservative addition, safety and convenience, thereby improving the quality of life and simultaneously reducing the application of systemic medicines.
Disclosure of Invention
The invention aims to provide a wet plaster for treating acute exudative dermatitis and eczema and a preparation method thereof, and aims to solve the problems in the prior art.
The technical scheme of the invention is as follows:
a wet plaster for treating acute exudative dermatitis and eczema comprises a carrier film cloth, an astringent, a humectant, a skin feel regulator and a pH regulator, wherein the carrier film cloth is a comprehensive spunlace non-woven fabric; the astringent comprises the following materials in parts by weight: 0.05-1.00% of Kepristine, 1.0-5.0% of stephania japonica extract and 1.0-5.0% of mussel extract; the humectant comprises the following materials in parts by weight: 0.5-5.0% of a humectant; the skin feel conditioning agent comprises the following materials in parts by weight: 0.05-0.50% menthol; the pH regulator comprises the following materials in parts by weight: 0.02-1.20% pH buffer solution.
Further, the skin feel modifier is menthol.
Further, the humectants are 1, 2, 3-propanediol and 1, 2-propanediol.
Further, the pH adjusting agent is sodium citrate.
A method for preparing the wet application for treating the acute exudative dermatitis and eczema comprises the following steps:
(1) accurately weighing purified water, the Kepristine, the stephania japonica extract and the mussel extract, and stirring to ensure that all raw materials are dissolved;
(2) taking a clean container, adding 1, 2, 3-propanetriol and sodium citrate, and stirring to ensure that all the raw materials are dissolved;
(3) adding the premixed solution in the step (2) into the mixed solution in the step (1) under the condition of stirring, and uniformly stirring until the solution is uniform;
(4) taking a clean container, adding 1, 2-propylene glycol and menthol, and dissolving in advance;
(5) adding the premixed solution obtained in the step (4) into the mixed solution obtained in the step (3) under the condition of stirring, stirring until the solution is uniform, and obtaining the solution required by the wet patch for treating the acute exudative dermatitis and eczema after preparation;
(6) and (5) adding the solution obtained in the step (5) into a bag filled with the folded carrier film cloth, and sealing by adopting vacuum hot pressing.
(7) And (4) sterilizing the sealed bag containing the solution and the membrane cloth obtained in the step (6) at high temperature and high pressure to obtain the wet plaster for treating the acute exudative dermatitis and eczema.
Further, the stirring speed is 100-200 rpm.
Further, the wet application bag is a high-temperature and high-pressure resistant material bag.
Further, the high temperature is 131 ℃, the high pressure is 103.4kPa, and the maintaining time is 15-30 minutes
The invention has the beneficial effects that:
1. the wet application for treating the acute exudation stage dermatitis and eczema provided by the invention has the advantages that when the wet application is used by patients with the acute exudation stage dermatitis and eczema, pruritus and redness and swelling are quickly eliminated, the injured skin is converged, and the further expansion of the damaged skin is prevented.
2. The skin-care product can adjust the skin feeling and the moistening degree of the diseased skin part, moisten the skin and provide a cool and refreshing repairing environment for the skin.
3. The wet application anticorrosion system is realized in a physical sterilization mode, can directly act on a lesion part, and has good safety.
The wet application system has the pH value of 6.0-6.5, is weakly acidic, and is harmless to human health.
Detailed Description
The following disclosure provides many different embodiments or examples for implementing different features of the invention. To simplify the disclosure of the present invention, the components and arrangements of specific examples are described below. Of course, they are merely examples and are not intended to limit the present invention. Furthermore, the present invention may repeat reference numerals and/or letters in the various examples, such repetition is for the purpose of simplicity and clarity and does not in itself dictate a relationship between the various embodiments and/or configurations discussed. In addition, the present invention provides examples of various specific processes and materials, but one of ordinary skill in the art may recognize applications of other processes and/or uses of other materials.
The invention provides a wet plaster for treating acute exudative dermatitis and eczema, which comprises carrier membrane cloth, an astringent, a humectant, a skin feel regulator and a pH regulator, wherein the carrier membrane cloth is comprehensive spunlace non-woven fabric; the astringent comprises the following materials in parts by weight: 0.05-1.00% of Kepristine, 1.0-5.0% of stephania japonica extract and 1.0-5.0% of mussel extract; the humectant comprises the following materials in parts by weight: 0.5-5.0% of a humectant; the skin feel conditioning agent comprises the following materials in parts by weight: 0.05-0.50% menthol; the pH regulator comprises the following materials in parts by weight: 0.02-1.20% pH buffer solution.
The weight ratio of the raw materials of the examples 1-3 is shown in the following table:
| raw materials/weight w/w% | Example 1 | Example 2 | Example 3 |
| Purified water | Balance of | Balance of | Balance of |
| Kaiputai (Kelpiostat) | 0.10 | 0.50 | 1.00 |
| 1, 2, 3-propanetriol | 5.00 | 2.50 | 1.50 |
| 1, 2-propanediol | 2.00 | 2.00 | 3.00 |
| Menthol | 0.05 | 0.50 | 0.20 |
| Stephania sinica Diels extract | 1.08 | 2.50 | 3.50 |
| Mussel extract | 5.00 | 3.00 | 4.00 |
| Citric acid sodium salt | 0.60 | 0.70 | 0.70 |
| pH value | 6.0～6.5 | 6.0～6.5 | 6.0～6.5 |
The preparation method of the wet patch in the embodiments 1 to 3 includes the following steps:
(1) accurately weighing purified water, the Kepristine, the stephania japonica extract and the mussel extract, stirring and dissolving to ensure that all raw materials are well dissolved;
(2) taking a clean container, adding 1, 2, 3-propanetriol and sodium citrate, stirring and dissolving to ensure that all raw materials are dissolved;
(3) adding the premixed solution in the step (2) into the mixed solution in the step (1) under the condition of stirring, and stirring until the solution is uniform;
(4) taking a clean container, adding 1, 2-propylene glycol and menthol, and dissolving in advance;
(5) adding the premixed solution obtained in the step (4) into the mixed solution obtained in the step (3) under the condition of stirring, stirring until the solution is uniform, and obtaining the solution required by the wet patch for treating the acute exudative dermatitis and eczema after preparation;
(6) and (5) adding the solution obtained in the step (5) into a bag filled with the folded carrier film cloth, and sealing by adopting vacuum hot pressing.
(7) And (4) sterilizing the sealed bag containing the solution and the membrane cloth obtained in the step (6) at high temperature and high pressure to obtain the wet plaster for treating the acute exudative dermatitis and eczema.
While the preferred embodiments of the present invention have been described in detail, it will be understood by those skilled in the art that the invention is not limited thereto, and that various changes and modifications may be made without departing from the spirit of the invention, and the scope of the appended claims is to be accorded the full scope of the invention.
Claims (8)
1. The wet plaster for treating acute exudative dermatitis and eczema is characterized by comprising carrier membrane cloth, an astringent, a humectant, a skin feel regulator and a pH regulator, wherein the carrier membrane cloth is comprehensive spunlace non-woven fabric; the astringent comprises the following materials in parts by weight: 0.05-1.00% of Kepristine, 1.0-5.0% of stephania japonica extract and 1.0-5.0% of mussel extract; the humectant comprises the following materials in parts by weight: 0.5-5.0% of a humectant; the skin feel conditioning agent comprises the following materials in parts by weight: 0.05-0.50% menthol; the pH regulator comprises the following materials in parts by weight: 0.02-1.20% pH buffer solution.
2. The wet patch for treating acute exudative dermatitis eczema according to claim 1, wherein the skin feel modifier is menthol.
3. The wet patch for treating eczema due to acute exudative dermatitis according to claim 1, wherein the moisturizers are 1, 2, 3-propanediol and 1, 2-propanediol.
4. The wet patch for treating eczema, dermatitis during acute exudation according to claim 1, wherein the pH regulator is sodium citrate.
5. A method for preparing a wet patch for treating eczema with acute exudative dermatitis according to claim 1, comprising the steps of:
(1) accurately weighing purified water, the Kepristine, the stephania japonica extract and the mussel extract, and stirring to ensure that all raw materials are dissolved;
(2) taking a clean container, adding 1, 2, 3-propanetriol and sodium citrate, and stirring to ensure that all the raw materials are dissolved;
(3) adding the premixed solution in the step (2) into the mixed solution in the step (1) under the condition of stirring, and uniformly stirring until the solution is uniform;
(4) taking a clean container, adding 1, 2-propylene glycol and menthol, and dissolving in advance;
(5) adding the premixed solution obtained in the step (4) into the mixed solution obtained in the step (3) under the condition of stirring, stirring until the solution is uniform, and obtaining the solution required by the wet patch for treating the acute exudative dermatitis and eczema after preparation;
(6) and (5) adding the solution obtained in the step (5) into a bag filled with the folded carrier film cloth, and sealing by adopting vacuum hot pressing.
(7) And (4) sterilizing the sealed bag containing the solution and the membrane cloth obtained in the step (6) at high temperature and high pressure to obtain the wet plaster for treating the acute exudative dermatitis and eczema.
6. The method for preparing the wet patch for treating the acute exudative dermatitis eczema as claimed in claim 5, wherein the stirring speed is 100-200 rpm.
7. The method for preparing the wet patch for treating the acute exudative dermatitis eczema as claimed in claim 5, wherein the wet patch bag is a high temperature and high pressure resistant material bag.
8. The method for preparing the wet patch for treating the acute exudative dermatitis and eczema according to claim 5, wherein the high temperature is 131 ℃, the high pressure is 103.4kPa, and the maintaining time is 15-30 minutes.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110108514.9A CN112870330A (en) | 2021-01-27 | 2021-01-27 | Wet plaster for treating acute exudative dermatitis and eczema and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110108514.9A CN112870330A (en) | 2021-01-27 | 2021-01-27 | Wet plaster for treating acute exudative dermatitis and eczema and preparation method thereof |
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| CN112870330A true CN112870330A (en) | 2021-06-01 |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| RU2417086C1 (en) * | 2009-11-10 | 2011-04-27 | Федеральное государственное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН "ФНЦ МПТ УРЗН" РОСПОТРЕБНАДЗОРА) | Agent for treating local allergic exudative-inflammatory and infiltrative-inflammatory skin processes |
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