CN112868968A - Carob bean and blood orange potion capable of regulating endocrine and preparation method thereof - Google Patents
Carob bean and blood orange potion capable of regulating endocrine and preparation method thereof Download PDFInfo
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- CN112868968A CN112868968A CN202110169015.0A CN202110169015A CN112868968A CN 112868968 A CN112868968 A CN 112868968A CN 202110169015 A CN202110169015 A CN 202110169015A CN 112868968 A CN112868968 A CN 112868968A
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- powder
- blood orange
- carob bean
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- extract
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention discloses a carob and blood orange potion capable of regulating endocrine and a preparation method thereof, belonging to the technical field of health-care drinks. It includes: according to the percentage, 50-55% of erythritol, 18-21% of isomaltitol, 15-17% of grapefruit juice powder, 4-6% of carob bean extract, 1.8-2.5% of anhydrous citric acid, 1.5-2.5% of red beet powder, 1.2-1.5% of vitamin C, 0.6-1% of instant green tea powder, 0.5-1% of blood orange powder, 0.5-1% of sour cherry concentrated powder, 0.35-0.5% of German chamomile extract, 0.35-0.5% of roselle powder and 0.15-0.23% of sucralose. The carob bean and blood orange potion capable of regulating endocrine effectively regulates the endocrine of a female organism and reduces the concentration of androgen in blood through mutual matching and coordination of substances, so that the balance of hormone in vivo is maintained, the physiological cycle of a female is favorably improved, and the carob bean and blood orange potion also has the effects of beautifying and whitening, calming the nerves and regulating sleep.
Description
Technical Field
The invention relates to the technical field of health-care drinks, and in particular relates to a carob and blood orange drink capable of regulating endocrine and a preparation method thereof.
Background
With the development of modern society, the requirements of people on life are improved, and the working pressure of the individual life is also improved. Different from men, women are affected by menstrual periods, and due to the fact that work and life pressure is high, self regulation is not good, irregular menstrual cycles and abnormal menstruation volume are easily caused, and the conditions of dysmenorrhea, low mood and poor self recovery after menstrual periods appear before the menstrual periods, so that the normal work and life of the women are seriously affected.
Traditional Chinese medicine considers that menstrual syndromes such as tension, dysphoria, dysmenorrheal and the like are mainly caused by liver depression and qi stagnation, unsmooth qi and blood circulation or qi and blood deficiency. Clinically, the diseases include qi stagnation and blood stasis, cold accumulation in uterus, deficiency of qi and blood, and downward flow of damp-heat. At present, although the cause and pathogenesis of menstrual syndrome are not well understood, modern medical research has confirmed that during menstruation, female endocrine system balance disorder (mainly disorder of estrogen and progesterone secretion) and nutrient deficiency or nutrient imbalance such as mineral and vitamin caused by massive blood loss are the root causes of menstrual syndrome. This condition currently lacks specific, normative treatments, mainly to enhance dietary conditioning and nutrient supplementation, i.e. dietetic therapy, to alleviate or eliminate symptoms. For severe patients, drugs or hormones can be supplemented for treatment, but the treatment drugs still have problems in the aspects of curative effect and toxic and side effects. The dietetic therapy is to take proper food or food according to different physical conditions and symptoms during and before menstruation of women and additionally supplement various essential nutrients such as protein, mineral substances, vitamins and the like during the physiological period of women so as to achieve the purposes of regulating qi and blood, removing blood stasis, relieving pain and recuperating the body and psychological states of women.
The existing solid beverage with health care property is added with corresponding effective component substances mainly by nourishing blood and enriching blood or supplementing a certain nutrient, has single function and poor compatibility among the substances, and has limited effect of improving endocrine.
Disclosure of Invention
The invention aims to provide a carob and blood orange drink capable of regulating endocrine and a preparation method thereof, and aims to solve the problems that the existing solid beverage for regulating the endocrine of women is single in function and unobvious in effect.
The technical scheme for solving the technical problems is as follows:
a carob fruit and blood orange drink capable of regulating endocrine, comprising: according to the percentage, 50-55% of erythritol, 18-21% of isomaltitol, 15-17% of grapefruit juice powder, 4-6% of carob bean extract, 1.8-2.5% of anhydrous citric acid, 1.5-2.5% of red beet powder, 1.2-1.5% of vitamin C, 0.6-1% of instant green tea powder, 0.5-1% of blood orange powder, 0.5-1% of sour cherry concentrated powder, 0.35-0.5% of German chamomile extract, 0.35-0.5% of roselle powder and 0.15-0.23% of sucralose.
In the invention, the carob bean extract, the sour cherry concentrated powder and the German chamomile extract are used as main active substances for regulating endocrine of the drinker, and the main active component of the carob bean extract is the chiral inositol, so that the endocrine of a female organism can be effectively regulated, the concentration of androgen in blood is reduced, the balance of hormone in the body is maintained, and the physiological cycle of the female is favorably improved. In addition, the carob bean extract also contains abundant vitamins and minerals, and has effect of reducing blood lipid.
Polysaccharide, quercetin, total flavone, high-content melatonin and oligomeric proanthocyanidin in the sour cherry concentrated powder, wherein the melatonin is a physiological sleep factor synthesized by a pineal body by taking tryptophan as a raw material, can maintain the balance of the melatonin in the body, regulate and restore the day and night rule, deepen the sleep and improve the sleep quality; the oligomeric proanthocyanidin contained in the composition can inhibit the degradation of tryptophan in the body, enhance the synthesis of endogenous sleep nutrient substances in the body, and is free from forming dependence. Regulating body hormone by improving sleep, thereby regulating endocrine. In addition, the sour cherry contains abundant phenolic substances such as anthocyanin and the like, and has good effects of scavenging free radicals and resisting oxidation.
Compared with other feverfew, the extract of the german chamomile contains more nutrients such as various flavones, heparin, alpha-bisabolol, caffeic acid, saccharides, various amino acids and the like, has excellent effects of whitening, promoting cell regeneration and skin metabolism, and is beneficial to enhancing the cell activity of organisms and improving the body immunity.
The grapefruit juice powder is rich in vitamin P, vitamin C and a large amount of antioxidant elements, has strong capacity of scavenging free radicals, and is beneficial to improving the organism and enhancing the resistance. The roselle powder has the effects of further improving the antioxidant capacity of the potion, delaying skin aging and improving the complexion, thereby achieving the effect of beautifying. The quick-frozen green tea powder has synergistic effect and enhances the oxidation resistance of the beverage. The inhibition effect of the carob bean extract on the free clearance rate and the antioxidation of the grapefruit juice powder also relieves the inhibition effect of the grapefruit juice powder on the grapefruit juice extract for reducing the concentration of androgen in blood, and further improves the free radical clearance rate of the grapefruit juice powder, thereby obtaining the effects of effectively regulating hormone balance, improving physiological cycle, and having good antioxidation and beauty treatment.
The anhydrous citric acid is used as an acidity regulator, can regulate the pH value and the acidity of the carob bean blood orange drink, has more efficient antioxidant performance, improves the flavor of the product, and has better mouthfeel.
Erythritol, isomaltitol and a small amount of sucralose are added, and the sugar alcohol is used as sugar substitute and is used as a sweetness additive, so that the beverage can obtain better mouthfeel by providing sweetness, and the use comfort of the product is improved. The sugar alcohol has low calorie, does not cause blood sugar rise, and better meets the new requirements of modern people on health.
The added vitamin C has the function of oxidation resistance while improving the acidity of the drink, has better capacity of eliminating free radicals, can prevent lipid peroxidation and the toxic action of certain chemical substances, and ensures the detoxification capacity and normal cell metabolism of the liver, thereby further improving the oxidation resistance of the carob bean blood orange drink and ensuring better beautifying effect.
Further, in a preferred embodiment of the present invention, the carob fruit orange drink capable of regulating endocrine includes: by percentage, 51.5% of erythritol, 19.5% of isomalt, 16% of grapefruit juice powder, 4.5% of carob bean extract, 2% of anhydrous citric acid, 2% of red beet powder, 1.3% of vitamin C, 0.8% of instant green tea powder, 0.7% of blood orange powder, 0.7% of sour cherry concentrate powder, 0.4% of German chamomile extract, 0.4% of roselle powder and 0.2% of sucralose.
Further, in a preferred embodiment of the present invention, the preparation method of the carob bean extract comprises the following steps: (1) primarily crushing carob, adding 60% ethanol, heating to 80-90 ℃, cooking and soaking overnight; (2) carrying out 8kgy irradiation treatment on the overnight soak solution by 60 Co-gamma rays for 0.5-1 h; (3) extruding the treated soak solution for 3-5 times; (4) treating the obtained treatment solution with anion exchange resin, drying, and grinding into powder.
According to the invention, after the smashed carob is smashed and is stewed and soaked, the active substances are preliminarily released, then the irradiation treatment and the full extrusion are carried out, so that the active substances can be fully released, then the carob extract with higher purity is obtained after the treatment by the anion exchange resin, and a good effect can be still obtained by adding a small amount of the carob extract.
Further, in a preferred embodiment of the present invention, the preparation method of the blood orange powder comprises the following steps: taking fresh blood orange pulp, chopping into large particles, carrying out ultrahigh pressure extrusion for 10-15 min under the pressure of 100-250 MPa, and drying.
The blood orange powder is obtained by drying after ultrahigh pressure extrusion, the ultrahigh pressure has a good sterilization effect, and the ultrahigh pressure treatment can extrude fresh blood orange pulp into tiny particles, retain the granular sensation of the pulp, and keep the unique taste of the fruit grains after dissolution.
Further, in a preferred embodiment of the present invention, the preparation method of the german chamomile extract comprises the following steps: (1) pulverizing German chamomile, adding 60% ethanol, performing microwave extraction, and recovering ethanol to obtain an extract concentrate; (2) diluting the concentrated extractive solution with water, and extracting with ethanol by countercurrent chromatography; (3) purifying the extract by macroporous adsorption resin, drying, and pulverizing again.
According to the invention, the German chamomile is subjected to microwave extraction, then is concentrated, and is purified after being extracted by a countercurrent chromatography, so that the purity of the German chamomile extract is effectively improved, and a good effect can be obtained by adding a small amount of the extract.
Further, in a preferred embodiment of the present invention, the preparation method of the above-mentioned sour cherry concentrated powder comprises the following steps:
(1) crushing fresh sour cherries, adding 0.5-0.7 g/L cellulase, and reacting at the temperature of 40-45 ℃ for 2-3 h to obtain enzymatic hydrolysate; (2) filtering the enzymolysis liquid, and concentrating at 30-50 ℃ under the vacuum degree of 0.8-1 MPa; (3) atomizing the concentrated solution into mist particles by a high-pressure spray gun, and drying the mist particles into powder at 40-50 ℃.
After enzymolysis and vacuum concentration, the effective components in the sour cherry are released and atomized into smaller particles, which are more soluble in water and easier to absorb.
The preparation method of the carob bean blood orange potion capable of regulating endocrine comprises the following steps:
(1) weighing and sieving:
(11) weighing blood orange concentrated powder, sour cherry extract, German chamomile extract and roselle powder, sieving with a 60-mesh sieve, and taking undersize as a first undersize;
(12) weighing instant green tea powder and sucralose, sieving with a 60-mesh sieve, and taking undersize as a second undersize;
(13) weighing anhydrous citric acid, sieving with a 40-mesh sieve, and taking undersize products as third undersize products;
(14) weighing carob bean extract and erythritol, sieving with 60 mesh sieve, and taking undersize as fourth undersize;
(15) weighing grapefruit juice powder, beet root powder, vitamin C and isomaltitol as additives;
(2) mixing:
(21) uniformly mixing the first undersize product and the second undersize product, and then uniformly premixing the first undersize product and the third undersize product;
(22) and (3) gradually mixing the premixed mixture, the fourth undersize product and the additive in an equal amount in a pyramid mixer for 20-30 min, and fully stirring until the mixture is uniformly mixed to prepare the carob bean blood orange guiding agent capable of regulating endocrine.
Further, in a preferred embodiment of the present invention, the moisture content of the carob bean blood orange guiding agent is less than 5%.
Further, in a preferred embodiment of the present invention, the above-mentioned packaging specification of the carob bean blood orange guiding agent is: 5 g/bar.
The citric acid anhydrous powder is screened according to the characteristics of each substance, and the anhydrous citric acid is acidic and needs to be screened separately; the roselle has certain oxidation resistance, and can prevent active ingredients from being oxidized when being mixed with the blood orange concentrated powder, the sour cherry extract and the German chamomile extract; the vitamin C has certain inoxidizability, and can avoid the invalidation of effective components when being mixed with grapefruit juice powder, beet root powder and isomaltulose; according to the characteristics of the composition, the activity of each group of effective components can be effectively ensured by adding the antioxidant during mixing.
The invention has the following beneficial effects:
1. the carob bean and blood orange potion capable of regulating endocrine effectively regulates the endocrine of a female organism and reduces the concentration of androgen in blood through mutual matching and coordination of substances, so that the balance of hormone in vivo is maintained, the physiological cycle of a female is favorably improved, and the carob bean and blood orange potion also has the effects of beautifying and whitening, calming the nerves and regulating sleep.
2. According to the characteristics of the substances, the substances are reasonably mixed in steps, so that the activity of the effective components of the substances is ensured, and the high-efficiency beverage is obtained.
3. The anhydrous citric acid, the erythritol, the isomaltitol, the sucralose and the blood orange powder are adopted, so that the sweet taste, the sour taste and the mouthfeel of the drink are effectively adjusted, and the experience of a quoted person is improved.
Detailed Description
The principles and features of this invention are described below in conjunction with embodiments, which are included to explain the invention and not to limit the scope of the invention. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
Example 1:
the carob bean blood orange drink capable of regulating endocrine of the embodiment comprises: according to percentage, 53.05% of erythritol, 21% of isomalt, 15% of grapefruit juice powder, 4% of carob bean extract, 1.8% of anhydrous citric acid, 1.5% of red beet powder, 1.2% of vitamin C, 0.6% of instant green tea powder, 0.5% of blood orange powder, 0.5% of sour cherry concentrate powder, 0.35% of German chamomile extract, 0.35% of roselle powder and 0.15% of sucralose.
The preparation method of the carob bean blood orange potion capable of regulating endocrine comprises the following steps:
(1) weighing and sieving:
(11) weighing blood orange concentrated powder, sour cherry extract, German chamomile extract and roselle powder, sieving with a 60-mesh sieve, and taking undersize as a first undersize;
(12) weighing instant green tea powder and sucralose, sieving with a 60-mesh sieve, and taking undersize as a second undersize;
(13) weighing anhydrous citric acid, sieving with a 40-mesh sieve, and taking undersize products as third undersize products;
(14) weighing carob bean extract and erythritol, sieving with 60 mesh sieve, and taking undersize as fourth undersize;
(15) weighing grapefruit juice powder, beet root powder, vitamin C and isomaltitol as additives;
(2) mixing:
(21) uniformly mixing the first undersize product and the second undersize product, and then uniformly premixing the first undersize product and the third undersize product;
(22) and (3) gradually mixing the premixed mixture, the fourth undersize product and the additive in a pyramid mixer for 20min in an equal amount, and fully stirring until the mixture is uniformly mixed to obtain the carob bean blood orange primer capable of regulating endocrine, wherein the water content of the primer is 3%.
The preparation method of the carob bean extract comprises the following steps: (1) primarily crushing carob, adding 60% ethanol, heating to 80 ℃, cooking and soaking overnight; (2) carrying out irradiation treatment on the overnight soak solution for 0.5h by using 60 Co-gamma rays and 8 kgy; (3) extruding the treated soak solution for 3 times; (4) treating the obtained treatment solution with anion exchange resin, drying, and grinding into powder.
The preparation method of the blood orange powder comprises the following steps: taking fresh blood orange pulp, mincing into large particles, squeezing under 100MPa for 10min under ultrahigh pressure, and drying.
The preparation method of the German chamomile extract comprises the following steps: (1) pulverizing German chamomile, adding 60% ethanol, performing microwave extraction, and recovering ethanol to obtain an extract concentrate; (2) diluting the concentrated extractive solution with water, and extracting with ethanol by countercurrent chromatography; (3) purifying the extract by macroporous adsorption resin, drying, and pulverizing again.
The preparation method of the sour cherry concentrated powder comprises the following steps:
(1) crushing fresh sour cherries, adding 0.5g/L cellulase, and reacting at 40 ℃ for 2h to obtain an enzymatic hydrolysate; (2) filtering the enzymolysis solution, and concentrating at 30 deg.C under vacuum degree of 0.8 MPa; (3) atomizing the concentrated solution into mist-like particles by a high-pressure spray gun, and drying the mist-like particles at 40 ℃ to form powder.
Example 2:
the carob bean blood orange drink capable of regulating endocrine of the embodiment comprises: by percentage, 50% of erythritol, 18% of isomalt, 15.27% of grapefruit juice powder, 6% of carob bean extract, 2.5% of anhydrous citric acid, 2.5% of red beet powder, 1.5% of vitamin C, 1% of instant green tea powder, 1% of blood orange powder, 1% of sour cherry concentrate powder, 0.5% of German chamomile extract, 0.5% of roselle powder and 0.23% of sucralose.
The preparation method of the carob bean blood orange potion capable of regulating endocrine comprises the following steps:
(1) weighing and sieving:
(11) weighing blood orange concentrated powder, sour cherry extract, German chamomile extract and roselle powder, sieving with a 60-mesh sieve, and taking undersize as a first undersize;
(12) weighing instant green tea powder and sucralose, sieving with a 60-mesh sieve, and taking undersize as a second undersize;
(13) weighing anhydrous citric acid, sieving with a 40-mesh sieve, and taking undersize products as third undersize products;
(14) weighing carob bean extract and erythritol, sieving with 60 mesh sieve, and taking undersize as fourth undersize;
(15) weighing grapefruit juice powder, beet root powder, vitamin C and isomaltitol as additives;
(2) mixing:
(21) uniformly mixing the first undersize product and the second undersize product, and then uniformly premixing the first undersize product and the third undersize product;
(22) and (3) gradually mixing the premixed mixture, the fourth undersize product and the additive in a pyramid mixer for 25min in an equal amount until the mixture is fully stirred and uniformly mixed to prepare the carob bean blood orange primer capable of regulating endocrine, wherein the water content of the primer is 3%.
The preparation method of the carob bean extract comprises the following steps: (1) primarily crushing carob, adding 60% ethanol, heating to 85 ℃, cooking and soaking overnight; (2) carrying out irradiation treatment on the overnight soak solution for 0.75h by using 60 Co-gamma rays and 8 kgy; (3) extruding the treated soak solution for 4 times; (4) treating the obtained treatment solution with anion exchange resin, drying, and grinding into powder.
The preparation method of the blood orange powder comprises the following steps: taking fresh blood orange pulp, mincing into large particles, squeezing under ultrahigh pressure of 175MPa for 12min, and drying.
The preparation method of the German chamomile extract comprises the following steps: (1) pulverizing German chamomile, adding 60% ethanol, performing microwave extraction, and recovering ethanol to obtain an extract concentrate; (2) diluting the concentrated extractive solution with water, and extracting with ethanol by countercurrent chromatography; (3) purifying the extract by macroporous adsorption resin, drying, and pulverizing again.
The preparation method of the sour cherry concentrated powder comprises the following steps:
(1) crushing fresh sour cherries, adding 0.6g/L cellulase, and reacting at 42 ℃ for 2.5h to obtain an enzymatic hydrolysate; (2) filtering the enzymolysis solution, and concentrating at 40 deg.C under vacuum degree of 0.9 MPa; (3) atomizing the concentrated solution into mist-like particles by a high-pressure spray gun, and drying the mist-like particles at 45 ℃ to form powder.
Example 3:
the carob bean blood orange drink capable of regulating endocrine of the embodiment comprises: according to percentage, the beverage comprises 52 percent of erythritol, 18.5 percent of isomalt, 16 percent of grapefruit juice powder, 5 percent of carob bean extract, 2 percent of anhydrous citric acid, 2 percent of red beet powder, 1.3 percent of vitamin C, 0.8 percent of instant green tea powder, 0.7 percent of blood orange powder, 0.7 percent of sour cherry concentrated powder, 0.4 percent of German chamomile extract, 0.4 percent of roselle powder and 0.2 percent of sucralose.
The preparation method of the carob bean blood orange potion capable of regulating endocrine comprises the following steps:
(1) weighing and sieving:
(11) weighing blood orange concentrated powder, sour cherry extract, German chamomile extract and roselle powder, sieving with a 60-mesh sieve, and taking undersize as a first undersize;
(12) weighing instant green tea powder and sucralose, sieving with a 60-mesh sieve, and taking undersize as a second undersize;
(13) weighing anhydrous citric acid, sieving with a 40-mesh sieve, and taking undersize products as third undersize products;
(14) weighing carob bean extract and erythritol, sieving with 60 mesh sieve, and taking undersize as fourth undersize;
(15) weighing grapefruit juice powder, beet root powder, vitamin C and isomaltitol as additives;
(2) mixing:
(21) uniformly mixing the first undersize product and the second undersize product, and then uniformly premixing the first undersize product and the third undersize product;
(22) gradually mixing the premixed mixture with the fourth undersize and additives in a pyramid mixer for 30min until the mixture is uniformly stirred to obtain the final product with water content of 3.5%.
The preparation method of the carob bean extract comprises the following steps: (1) primarily crushing carob, adding 60% ethanol, heating to 90 ℃, cooking and soaking overnight; (2) carrying out irradiation treatment on the overnight soak solution for 1h by 60 Co-gamma rays with the intensity of 8 kgy; (3) extruding the treated soak solution for 5 times; (4) treating the obtained treatment solution with anion exchange resin, drying, and grinding into powder.
The preparation method of the blood orange powder comprises the following steps: taking fresh blood orange pulp, mincing into large particles, squeezing under 250MPa for 15min under ultrahigh pressure, and drying.
The preparation method of the German chamomile extract comprises the following steps: (1) pulverizing German chamomile, adding 60% ethanol, performing microwave extraction, and recovering ethanol to obtain an extract concentrate; (2) diluting the concentrated extractive solution with water, and extracting with ethanol by countercurrent chromatography; (3) purifying the extract by macroporous adsorption resin, drying, and pulverizing again.
The preparation method of the sour cherry concentrated powder comprises the following steps:
(1) crushing fresh sour cherries, adding 0.7g/L cellulase, and reacting at 45 ℃ for 3h to obtain an enzymatic hydrolysate; (2) filtering the enzymolysis solution, and concentrating at 50 deg.C under vacuum degree of 1 MPa; (3) atomizing the concentrated solution into mist particles by a high-pressure spray gun, and drying the mist particles into powder at 40-50 ℃.
Example 4
The carob bean blood orange drink capable of regulating endocrine of the embodiment comprises: by percentage, 55% of erythritol, 18.2% of isomalt, 15.5% of grapefruit juice powder, 4% of carob bean extract, 1.8% of anhydrous citric acid, 1.5% of red beet powder, 1.2% of vitamin C, 0.7% of instant green tea powder, 0.6% of blood orange powder, 0.6% of sour cherry concentrated powder, 0.4% of German chamomile extract, 0.35% of roselle powder and 0.15% of sucralose.
The preparation method of the carob bean and blood orange drink capable of regulating endocrine in the embodiment is the same as that in the embodiment 1, and the preparation method of the carob bean extract, the blood orange powder, the sour cherry concentrated powder and the Germany chamomile extract is the same as that in the embodiment 1.
Example 5
The carob bean blood orange drink capable of regulating endocrine of the embodiment comprises: by percentage, 51% of erythritol, 19% of isomalt, 17% of grapefruit juice powder, 4.5% of carob bean extract, 1.9% of anhydrous citric acid, 1.8% of red beet powder, 1.4% of vitamin C, 0.8% of instant green tea powder, 0.8% of blood orange powder, 0.8% of sour cherry concentrate powder, 0.35% of German chamomile extract, 0.45% of roselle powder and 0.2% of sucralose.
The preparation method of the carob bean and blood orange drink capable of regulating endocrine in the embodiment is the same as that in the embodiment 2, and the preparation method of the carob bean extract, the blood orange powder, the sour cherry concentrated powder and the Germany chamomile extract is the same as that in the embodiment 2.
Test 1: androgen testosterone level detection
The test object is used for searching 20 female volunteers with irregular physiological cycle and endocrine dyscrasia, the age is 25-35 years, and the exclusion standard is as follows: hirsutism and polycystic ovarian syndrome complicated with acne; pregnant or lactating women; patients with heart, liver and renal insufficiency; for those who are allergic to the medicine and who cannot take the medicine according to the medical advice; glucocorticoid, antibiotic and retinoid drugs are used in the last month.
The test method comprises the following steps: dividing 20 volunteers into 2 groups, one group is an experimental group, and the other group is a blank control group, wherein the experimental group is prepared from the carob bean blood orange potion prepared in the example 1, adding about 120mL warm water, brewing and stirring uniformly, one bag per day, and continuously drinking for 6 months; the blank control group does not drink carob bean blood orange drinking agent, adds about 120mL of warm water every day, and continuously drinks for 6 months; the level detection of the male hormone testosterone is respectively carried out on volunteers of an experimental group and a blank control group before, 1 month, 3 months and 6 months of the test, and the detection method comprises the following steps: each volunteer draws 3mL of venous blood at 8:00-10:00 am, places the venous blood in a dry non-anticoagulation test tube, stands and coagulates at normal temperature, centrifugally separates serum, stores the serum at-20 ℃ for testing, adopts a full-automatic electrochemiluminescence immunoassay analyzer to detect the level of androgen testosterone (the normal range is 3-60 mg/DL), processes data, records the obtained data by mean plus or minus standard deviation, and has the following results:
as can be seen from the above table, long-term administration of the carob bean blood orange drink of the present invention can reduce the level of testosterone, an androgen in the blood, thereby maintaining hormone balance, and further effectively regulating hormone balance, thereby regulating the menstrual homeostasis of women to a more normal healthy level.
Test example 2: DPPH radical clearance rate
Taking 3mL of 0.0178mmol/L DPPH-absolute methanol solution into a cuvette, adding 3mL of 0.8mg/mL solution to be tested prepared by the carob bean blood orange potables prepared in each embodiment and comparative example, uniformly mixing, and immediately measuring the light absorption value at the wavelength of 517nm to obtain a test group A1; then storing the mixture at 37 ℃ in dark for 30min, and measuring the light absorption value as A2; and the blank control group is a control group which is only added with DPPH-absolute methanol solution and is marked as A3; DPPH radical clearance was calculated as follows: DPPH free radical clearance (%) [1- (a1-a2)/A3] 100%, averaged over three measurements, with the following results:
the free radical clearance of the test group is 93.5 percent, the free radical clearance of the control group is 0.5 percent, which shows that the potion has high free radical clearance of 93.5 percent, has strong oxidation resistance, delays skin aging and keeps skin in a healthy state, thereby achieving the effects of whitening and beautifying.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (9)
1. A carob fruit orange drink capable of regulating endocrine, comprising: according to the percentage, 50-55% of erythritol, 18-21% of isomaltitol, 15-17% of grapefruit juice powder, 4-6% of carob bean extract, 1.8-2.5% of anhydrous citric acid, 1.5-2.5% of red beet powder, 1.2-1.5% of vitamin C, 0.6-1% of instant green tea powder, 0.5-1% of blood orange powder, 0.5-1% of sour cherry concentrated powder, 0.35-0.5% of German chamomile extract, 0.35-0.5% of roselle powder and 0.15-0.23% of sucralose.
2. The carob bean blood orange drink capable of regulating endocrine according to claim 1, comprising: by percentage, 51.5% of erythritol, 19.5% of isomalt, 16% of grapefruit juice powder, 4.5% of carob bean extract, 2% of anhydrous citric acid, 2% of red beet powder, 1.3% of vitamin C, 0.8% of instant green tea powder, 0.7% of blood orange powder, 0.7% of sour cherry concentrate powder, 0.4% of German chamomile extract, 0.4% of roselle powder and 0.2% of sucralose.
3. The carob bean blood orange drink capable of regulating endocrine according to claim 1 or 2, characterized in that the carob bean extract is prepared by a method comprising the steps of: (1) primarily crushing carob, adding 60% ethanol, heating to 80-90 ℃, cooking and soaking overnight; (2) carrying out 8kgy irradiation treatment on the overnight soak solution by 60 Co-gamma rays for 0.5-1 h; (3) extruding the treated soak solution for 3-5 times; (4) treating the obtained treatment solution with anion exchange resin, drying, and grinding into powder.
4. The carob bean blood orange drink capable of regulating endocrine according to claim 1 or 2, characterized in that the preparation method of the blood orange powder comprises the following steps: taking fresh blood orange pulp, chopping into large particles, carrying out ultrahigh pressure extrusion for 10-15 min under the pressure of 100-250 MPa, and drying.
5. The carob bean blood orange drink capable of regulating endocrine according to claim 1 or 2, characterized in that the preparation method of the german chamomile extract comprises the following steps: (1) pulverizing German chamomile, adding 60% ethanol, performing microwave extraction, and recovering ethanol to obtain an extract concentrate; (2) diluting the concentrated extractive solution with water, and extracting with ethanol by countercurrent chromatography; (3) purifying the extract by macroporous adsorption resin, drying, and pulverizing again.
6. The carob bean blood orange drink capable of regulating endocrine according to claim 1 or 2, characterized in that the preparation method of the sour cherry concentrated powder comprises the following steps:
(1) crushing fresh sour cherries, adding 0.5-0.7 g/L cellulase, and reacting at the temperature of 40-45 ℃ for 2-3 h to obtain enzymatic hydrolysate; (2) filtering the enzymolysis liquid, and concentrating at 30-50 ℃ under the vacuum degree of 0.8-1 MPa; (3) atomizing the concentrated solution into mist particles by a high-pressure spray gun, and drying the mist particles into powder at 40-50 ℃.
7. The method for preparing a carob bean blood orange drink capable of regulating endocrine according to any one of claims 1 to 6, comprising the steps of:
(1) weighing and sieving:
(11) weighing blood orange concentrated powder, sour cherry extract, German chamomile extract and roselle powder, sieving with a 60-mesh sieve, and taking undersize as a first undersize;
(12) weighing instant green tea powder and sucralose, sieving with a 60-mesh sieve, and taking undersize as a second undersize;
(13) weighing anhydrous citric acid, sieving with a 40-mesh sieve, and taking undersize products as third undersize products;
(14) weighing carob bean extract and erythritol, sieving with 60 mesh sieve, and taking undersize as fourth undersize;
(15) weighing grapefruit juice powder, beet root powder, vitamin C and isomaltitol as additives;
(2) mixing:
(21) uniformly mixing the first undersize product and the second undersize product, and then uniformly premixing the first undersize product and the third undersize product;
(22) and (3) gradually mixing the premixed mixture, the fourth undersize product and the additive in an equal amount in a pyramid mixer for 20-30 min, and fully stirring until the mixture is uniformly mixed to prepare the carob bean blood orange guiding agent capable of regulating endocrine.
8. The method for producing a carob bean blood orange drink according to claim 7, wherein the carob bean blood orange drink has a moisture content of less than 5%.
9. The method for preparing a carob bean blood orange drink capable of regulating endocrine according to claim 7, wherein the packaging specification of the carob bean blood orange drink is as follows: 5 g/bar.
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Application publication date: 20210601 |