CN112867475B - 具有单分散流体体积的含颗粒液滴系统 - Google Patents

具有单分散流体体积的含颗粒液滴系统 Download PDF

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CN112867475B
CN112867475B CN201980068109.XA CN201980068109A CN112867475B CN 112867475 B CN112867475 B CN 112867475B CN 201980068109 A CN201980068109 A CN 201980068109A CN 112867475 B CN112867475 B CN 112867475B
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droplet
carrier particles
particles
carrier
dimensional hydrophilic
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CN112867475A (zh
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迪诺·迪·卡洛
约瑟夫·德·鲁特
罗伯特·迪马特奥
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University of California
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University of California
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0004Preparation of sols
    • B01J13/0026Preparation of sols containing a liquid organic phase
    • B01J13/003Preparation from aqueous sols
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0052Preparation of gels
    • B01J13/0065Preparation of gels containing an organic phase
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0052Preparation of gels
    • B01J13/0069Post treatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/12Powdering or granulating
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/24Crosslinking, e.g. vulcanising, of macromolecules
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/44Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Power Engineering (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
CN201980068109.XA 2018-08-17 2019-08-16 具有单分散流体体积的含颗粒液滴系统 Active CN112867475B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862719476P 2018-08-17 2018-08-17
US62/719,476 2018-08-17
PCT/US2019/046835 WO2020037214A1 (en) 2018-08-17 2019-08-16 Particle-containing droplet systems with monodisperse fluid volumes

Publications (2)

Publication Number Publication Date
CN112867475A CN112867475A (zh) 2021-05-28
CN112867475B true CN112867475B (zh) 2024-03-22

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Country Status (7)

Country Link
US (1) US20210268465A1 (de)
EP (1) EP3836887B1 (de)
JP (1) JP2021534402A (de)
CN (1) CN112867475B (de)
AU (1) AU2019321593A1 (de)
CA (1) CA3109426A1 (de)
WO (1) WO2020037214A1 (de)

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WO2018132732A1 (en) 2017-01-12 2018-07-19 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
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US20230173497A1 (en) * 2020-04-29 2023-06-08 Hewlett-Packard Development Company, L.P. Nucleic acid amplification
US20230173449A1 (en) * 2020-04-30 2023-06-08 The Regents Of The University Of California Systems and methods for multiphase droplet generation for generating shaped particles and uses thereof
JP2023524524A (ja) * 2020-05-04 2023-06-12 スリングショット バイオサイエンシーズ, インコーポレイテッド 多重化アッセイのためのパッシブ光学バーコード付与のための組成物および方法
US20230257732A1 (en) * 2020-08-05 2023-08-17 The Regents Of The University Of California Degradable hollow shell particles for high-throughput screening and sorting of cells
WO2022240655A1 (en) * 2021-05-10 2022-11-17 The Regents Of The University Of California Methods of using shaped particles in flow cytometers for assays on b cells and t cells
WO2022245827A1 (en) * 2021-05-18 2022-11-24 Fluent Biosciences Inc. Pre-templated instant partitions for screening
CA3220479A1 (en) * 2021-05-18 2022-11-24 Fluent Biosciences Inc. Template particles with micropores and nanopores
WO2023072809A1 (en) * 2021-10-29 2023-05-04 Droplet Genomics, Uab Microspheroids containing distinguishable microparticle patterns
WO2023129514A2 (en) * 2021-12-28 2023-07-06 The Texas A&M University System Environmental biospecimen recovery after in-droplet gel encapsulation
WO2024155630A2 (en) * 2023-01-17 2024-07-25 The Regents Of The University Of California Therapeutic polynucleotides encoding t cell receptor (tcr) alpha chain polypeptides and/or tcr beta chain polypeptides
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US20210268465A1 (en) 2021-09-02
WO2020037214A1 (en) 2020-02-20
CN112867475A (zh) 2021-05-28
JP2021534402A (ja) 2021-12-09
EP3836887B1 (de) 2024-07-17
CA3109426A1 (en) 2020-02-20
EP3836887A4 (de) 2021-10-13
AU2019321593A1 (en) 2021-03-18
EP3836887A1 (de) 2021-06-23

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