CN112843167A - Traditional Chinese medicine additive for promoting lactation of sows and preparation method thereof - Google Patents
Traditional Chinese medicine additive for promoting lactation of sows and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The invention is suitable for the technical field of feed additives, and provides a traditional Chinese medicine additive for promoting sow lactation, which comprises the following raw materials in parts by weight: 90-110 parts of motherwort, 45-55 parts of angelica, 45-55 parts of radix astragali preparata, 40-50 parts of uniflower swisscentaury root, 40-50 parts of cluster mallow seed, 30-40 parts of cyperus rotundus, 30-40 parts of salvia miltiorrhiza and 20-30 parts of epimedium herb. The invention also provides a preparation method of the traditional Chinese medicine additive for promoting sow lactation. The traditional Chinese medicine microecological preparation is prepared by taking a traditional Chinese medicine extract as a fermentation raw material, performing biotransformation on intermediate substances by using lactobacillus acidophilus and saccharomyces cerevisiae and adding soybean isoflavone, is nontoxic, residue-free, green and easy to absorb, can effectively promote lactation of sows, has a short production period, is low in cost and stable in process, and is suitable for batch production.
Description
Technical Field
The invention relates to the technical field of feed additives, in particular to a traditional Chinese medicine additive for promoting sow lactation and a preparation method thereof.
Background
With the development of modern animal husbandry, the large-scale, intensive and modern pig raising is a trend of the current development. In pig production, the most important factor determining the production level and economic benefit of a pig farm is the reproductive performance of sows. Due to continuous genetic breeding, the litter size of the sows and the birth weight of the piglets are continuously increased, and the lactation performance is also obviously improved so as to ensure that the sows have sufficient milk to meet the growth of the piglets. The breast milk is an important nutrient source of the suckling piglets, the colostrum contains rich immunoglobulin, so that the piglets can obtain passive immunity, and the growth speed and the survival rate of the piglets are closely related to the lactation performance of the sows. The lactation performance of the nursing sow directly influences the growth and development of the suckling piglets, and is concerned with the survival rate, the growth and development, the immunity level and the acquired productivity of the weaning piglets. If the lactation amount of the sow is insufficient and the quality of the milk is poor, malnutrition of the suckling piglets can be directly caused, the growth and development are slow, the death rate is increased, the weaning weight of the piglets is influenced, the weaning stress of the piglets is further aggravated, and the growth and development in the later period can be influenced. In addition, a certain nutrient substance is stored in the sow body to prepare for the next-stage breeding, if the feed intake of the sow in the lactation period is insufficient, the maintaining requirement and the lactation requirement of the sow can not be met, so that the excessive waist falling and weight loss of the sow in the lactation period are caused, the growth and development of piglets are poor, a chain reaction is caused, and the elimination rate of the sow is increased. Therefore, the method is an important way to improve the reproductive performance of the sows and ensure the lactation performance and body condition of the sows in the lactation period.
For a long time, lactating sows are mainly concerned about nutrition supply, disease defense, breeding strategies and management measures, and the oxidative stress problem caused by vigorous metabolism of the sow body is often easily ignored due to various factors such as physiology, nutrition, management and environment of the sow. Researches show that the physiological and nutritional metabolism of sows in the late gestation period and the lactation period of sows is greatly changed, particularly the metabolism of endocrine systems, fat and protein, and the body has serious systemic oxidative stress. The excessive free radicals can increase the metabolic burden of an organism, reduce the capacity of taking nutrients by mammary cells, increase inflammatory factors in milk and reduce the content of immunoglobulin in the milk, thereby reducing the lactation performance of sows and the growth speed and survival rate of suckling piglets.
The phenomenon that the milking performance of female animals is reduced is a phenomenon which often occurs in a farm, particularly in the south, middle and east regions of China, the indexes such as the milking performance, the number born and the like of the female animals are obviously reduced, the difficult yield and the death rate of the female animals are increased, and great economic loss is caused to the farm due to the fact that the high-temperature weather in summer often causes the indexes; the lactation performance of female animals is reduced, the newborn animals can not obtain sufficient milk, the growth speed is reduced, and the death rate is increased; in addition, the high-temperature weather obviously reduces the feed intake of lactating female animals, which leads to the decline of physical ability, thereby influencing the breeding capability of the next production cycle.
The productivity of the lactating sow directly determines the vitality of piglets and weight of weaning litter, and a quite special and critical period in the breeding cycle of the sow has great influence on the economic benefit of a pig farm. This stage of nutrition and management discomfort can cause the sow to develop mastitis, little or no milk, several days after delivery. The prolactin is generally directly used for increasing the lactation amount in clinic, most sows can quickly release milk after prolactin injection, but the method maintains that the normal lactation period of the sows is short, and some sows directly stop the milk after releasing the milk for multiple times.
Disclosure of Invention
The embodiment of the invention provides a traditional Chinese medicine additive for promoting sow lactation, which aims to take traditional Chinese medicine extracts as fermentation raw materials, utilize lactobacillus acidophilus and saccharomyces cerevisiae to carry out biotransformation on intermediate substances, and add soybean isoflavone to prepare a non-toxic, residue-free, green and easily-absorbed traditional Chinese medicine microecological preparation, so that sow lactation is effectively promoted.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
a traditional Chinese medicine additive for promoting lactation of sows comprises the following raw materials in parts by weight:
90-110 parts of motherwort, 45-55 parts of angelica, 45-55 parts of radix astragali preparata, 40-50 parts of uniflower swisscentaury root, 40-50 parts of cluster mallow seed, 30-40 parts of cyperus rotundus, 30-40 parts of salvia miltiorrhiza and 20-30 parts of epimedium herb.
Further comprises 300 parts of fermentation medium 200-300 parts and 25-45 parts of probiotic bacteria.
Further, the probiotic bacteria are prepared from lactobacillus acidophilus and saccharomyces cerevisiae according to the mass ratio of (1-3): 5 are compounded.
Furthermore, the effective viable count of the probiotic is more than or equal to 200 hundred million/g.
Further, the fermentation medium comprises glucose, vitamin B, folic acid and lysine.
Further, the content of lysine in the fermentation medium is more than or equal to 12.5%.
The invention also provides a preparation method of the traditional Chinese medicine additive for promoting sow lactation, which comprises the following steps:
1) weighing motherwort, Chinese angelica, radix astragali preparata, uniflower swisscentaury root, cluster mallow fruit, cyperus rotundus, salvia miltiorrhiza and epimedium in corresponding parts by weight for later use;
2) mixing the weighed components, pouring the mixture into a grinder for shearing and grinding, then pouring the ground material into a fermentation medium for uniformly mixing, inoculating probiotic bacteria, and fermenting for 24-48 h to obtain a liquid fermentation water aqua;
3) drying the prepared liquid fermentation water agent to obtain a solid fermentation agent;
4) adding soybean isoflavone 0.1 wt% into the solid fermentation agent, and mixing to obtain the Chinese medicinal additive.
Further, the fermentation temperature in the step 2) is 36-38 ℃.
Further, a spray dryer is adopted to dry the liquid fermentation water in the step 3).
The invention has the following beneficial effects:
the traditional Chinese medicine microecological preparation is prepared by taking a traditional Chinese medicine extract as a fermentation raw material, performing biotransformation on intermediate substances by using lactobacillus acidophilus and saccharomyces cerevisiae and adding soybean isoflavone, is nontoxic, residue-free, green and easy to absorb, can effectively promote lactation of sows, has a short production period, is low in cost and stable in process, and is suitable for batch production.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Cyclic nucleotides are small molecule regulatory substances widely present in animals, which mediate various physiological regulation of hormones, transmitters and the like on cells, including regulation of lactation function, by changing protein kinase activity or gene regulation. Experiments prove that the application of the exogenous cyclic nucleotide can improve the yield of the dairy cows, and the exogenous cyclic nucleotide cannot be widely popularized and used in production at present due to the technology and price. The research proves that when the Chinese herbal medicine extract is added into the feed of the lactating sows, the cyclic nucleotide level is obviously improved, so that the milk yield is increased.
Prolactin is a neuropeptide protein hormone produced by pituitary and extrapituitary cells, has the main effects of promoting the growth and development of mammary glands under the coordination of other hormones in vivo, starting and maintaining lactation, maintaining gestational corpus luteum, and providing proper internal environment for the growth and development of fetuses and promoting the growth and development of fetuses. The research proves that when the Chinese herbal medicine extract is added into the feed for nursing sows, the prolactin level is obviously improved, so that the milk yield is increased.
Soy isoflavone phytoestrogens are bioactive substances found in soy, and are structurally and functionally similar to estradiol. The compound feed has the functions of improving the humoral immunity of the whole pregnant sow and mammary organs, improving the maternal antibody level in the newborn piglet body and increasing the lactation capacity of the sow; the soybean isoflavone with estrogenic activity can promote mammary gland development and increase prolactin.
The probiotics (lactobacillus acidophilus and saccharomyces cerevisiae) are used as antigens, can stimulate the immune organ development of a host, accelerate the immune function maturation, effectively resist interferon, stimulate the immunity to stimulate the humoral immunity and cellular immunity of an organism by generating antibodies, improving the phagocytic activity and the like, improve the integral disease resistance, help to eliminate mastitis, and improve the lactation capacity of lactating sows.
Specifically, the embodiment of the invention provides a traditional Chinese medicine additive for promoting lactation of sows, which comprises the following raw materials in parts by weight:
90-110 parts of motherwort, 45-55 parts of angelica, 45-55 parts of radix astragali preparata, 40-50 parts of uniflower swisscentaury root, 40-50 parts of cluster mallow seed, 30-40 parts of cyperus rotundus, 30-40 parts of salvia miltiorrhiza and 20-30 parts of epimedium herb.
In the embodiment of the invention, the microbial inoculum further comprises 300 parts of a fermentation culture medium 200-45 parts of probiotic bacteria.
In the embodiment of the invention, the probiotic bacteria are prepared from lactobacillus acidophilus and saccharomyces cerevisiae according to the mass ratio of (1-3): 5 are compounded.
In the embodiment of the invention, the effective viable count of the probiotic is more than or equal to 200 hundred million/g.
In the embodiment of the invention, the fermentation medium comprises glucose, vitamin B, folic acid and lysine.
In the embodiment of the invention, the content of lysine in the fermentation medium is more than or equal to 12.5%.
The invention also provides a preparation method of the traditional Chinese medicine additive for promoting sow lactation, which comprises the following steps:
1) weighing motherwort, Chinese angelica, radix astragali preparata, uniflower swisscentaury root, cluster mallow fruit, cyperus rotundus, salvia miltiorrhiza and epimedium in corresponding parts by weight for later use;
2) mixing the weighed components, pouring the mixture into a grinder for shearing and grinding, then pouring the ground material into a fermentation medium for uniformly mixing, inoculating probiotic bacteria, and fermenting for 24-48 h to obtain a liquid fermentation water aqua;
3) drying the prepared liquid fermentation water agent to obtain a solid fermentation agent;
4) adding soybean isoflavone 0.1 wt% into the solid fermentation agent, and mixing to obtain the Chinese medicinal additive.
In the embodiment of the invention, the fermentation temperature in the step 2) is 36-38 ℃.
In the embodiment of the invention, a spray dryer is adopted to dry the liquid fermentation water in the step 3).
The technical solution and the technical effect of the present invention will be further described by specific examples.
Example 1
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 2
Weighing 100g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 3
Weighing 110g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 4
Weighing 90g of motherwort, 50g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 5
Weighing 90g of motherwort, 55g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 6
Weighing 90g of motherwort, 45g of Chinese angelica, 50g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 7
Weighing 90g of motherwort, 45g of Chinese angelica, 55g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 8
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 35g of cyperus rotundus, 30g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 9
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 40g of cyperus rotundus, 30g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 10
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 35g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 11
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 40g of red-rooted salvia root and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 12
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 25g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 13
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of red-rooted salvia root and 30g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 14
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 2: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 15
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 3: 5 compounding probiotic bacteria, and taking 25g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 16
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 35g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Example 17
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 45g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Control group
The additive for promoting the lactation of the sow is generally sold in the market.
The additives for promoting the lactation of the sows in the examples 1-17 and the comparative examples are respectively added into feed, 180 pregnant sows with similar fat condition, fetal times, body weight, good health condition and normal nipples are selected and randomly divided into 18 groups, and 10 sows in each group. The feed was fed to each group of sows from the start of delivery to the end of the 28 day weaning. The daily average and total milk secretion of each group of single sows is measured, and the specific measurement results are shown in the following table 1:
TABLE 1
As can be seen from the table 1, compared with the commercially available common additive for promoting the lactation of sows, the traditional Chinese medicine additive for promoting the lactation of sows, prepared by the invention, remarkably improves the daily average lactation amount and total lactation amount of sows in the lactation period; the feed added with the traditional Chinese medicine additive for promoting sow lactation, prepared in example 16, has the best effect of promoting sow lactation; compared with the common additives sold in the market, the traditional Chinese medicine additive disclosed by the invention has the advantages that the lactation yield of the sows is improved by at least 27%, and the improvement effect is obvious.
Further, based on the preparation steps of example 16, the invention performs a single factor deletion comparison experiment on the probiotic bacteria and the soy isoflavone, and the experiment result shows that different factors are deleted, and the finally prepared additive has a certain difference in the effect of promoting the lactation of the sows, and the following comparison examples are provided.
Comparative example 1
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; pouring the crushed material into a standby fermentation medium, and uniformly mixing to obtain a liquid fermentation water agent; putting the prepared liquid fermentation water agent into a spray dryer for drying treatment to obtain a solid fermentation agent; finally, adding the soybean isoflavone into the solid-state leavening agent according to the weight ratio of 0.1 percent, and uniformly mixing to obtain the traditional Chinese medicine additive.
Comparative example 2
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; lactobacillus acidophilus and Saccharomyces cerevisiae are mixed according to the mass ratio of 1: 5 compounding probiotic bacteria, and taking 35g of probiotic bacteria for later use; pouring the crushed material into a standby fermentation culture medium, uniformly mixing, inoculating standby probiotic bacteria into the fermentation culture medium, and fermenting at 37 ℃ for 48 hours to obtain a liquid fermentation water aqua; drying the obtained liquid fermented water solution in a spray dryer to obtain solid fermentation agent, and to obtain Chinese medicinal additive.
Comparative example 3
Weighing 90g of motherwort, 45g of Chinese angelica, 45g of radix astragali preparata, 45g of uniflower swisscentaury root, 45g of cluster mallow seed, 30g of cyperus rotundus, 30g of salvia miltiorrhiza and 20g of epimedium herb, mixing the weighed components, pouring the mixture into a grinder, and shearing and grinding the mixture for 30min at the rotating speed of 800r/min to obtain ground materials; mixing glucose, vitamin B, folic acid and lysine according to a mass ratio of 10: 2: 2: 3 preparing a fermentation culture medium, and taking 200g of the fermentation culture medium for later use; pouring the crushed material into a standby fermentation medium, and uniformly mixing to obtain a liquid fermentation water agent; drying the obtained liquid fermented water solution in a spray dryer to obtain solid fermentation agent, and mixing to obtain the Chinese medicinal additive.
The additives for promoting the lactation of the sows in the comparative examples 1-3 are respectively added into the feed, 30 pregnant sows with similar fat condition, fetal times, body weight, good health condition and normal nipples are selected and randomly divided into 3 groups, and 10 sows in each group. The feed was fed to each group of sows from the start of delivery to the end of the 28 day weaning. The daily average and total milk secretion of each group of single sows is measured, and the specific measurement results are shown in the following table 2:
TABLE 2
| Numbering | Item of implementation | Probiotic bacteria | Soy isoflavone | Average daily milk secretion/kg | Total lactation/kg |
| 1 | Example 16 | √ | √ | 7.34 | 205.52 |
| 19 | Comparative example 1 | √ | 4.32 | 120.96 | |
| 20 | Comparative example 2 | √ | 4.68 | 131.04 | |
| 21 | Comparative example 3 | 2.52 | 70.56 |
As can be seen from table 2, the average daily milk yield and the total milk yield of the sows in the lactation period are greatly improved by using the additive for promoting the lactation of the sows, which is prepared by the invention, compared with the use of the probiotic bacteria and the soy isoflavone alone.
In general, the traditional Chinese medicine micro-ecological preparation is prepared by taking traditional Chinese medicine extracts as fermentation raw materials, performing biotransformation on intermediate substances by using lactobacillus acidophilus and saccharomyces cerevisiae and adding soybean isoflavone, is nontoxic, residue-free, green and easy to absorb, can effectively promote lactation of sows, has short production period, lower cost and stable process, and is suitable for batch production.
It should be understood that the above-mentioned embodiments are only preferred embodiments of the present invention, and are not intended to limit the present invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The traditional Chinese medicine additive for promoting lactation of sows is characterized by comprising the following raw materials in parts by weight:
90-110 parts of motherwort, 45-55 parts of angelica, 45-55 parts of radix astragali preparata, 40-50 parts of uniflower swisscentaury root, 40-50 parts of cluster mallow seed, 30-40 parts of cyperus rotundus, 30-40 parts of salvia miltiorrhiza and 20-30 parts of epimedium herb.
2. The traditional Chinese medicine additive for promoting lactation of sows according to claim 1, which is characterized by comprising the following raw materials in parts by weight:
100 parts of motherwort, 50 parts of angelica, 50 parts of radix astragali preparata, 45 parts of uniflower swisscentaury root, 45 parts of cluster mallow seed, 35 parts of cyperus rotundus, 35 parts of salvia miltiorrhiza and 25 parts of epimedium.
3. The traditional Chinese medicine additive for promoting lactation of sows as claimed in claim 1, which further comprises 300 parts of fermentation medium 200-45 parts of probiotic bacteria.
4. The traditional Chinese medicine additive for promoting lactation of sows according to claim 3, wherein the probiotic bacteria consist of Lactobacillus acidophilus and Saccharomyces cerevisiae in a mass ratio of (1-3): 5 are compounded.
5. The traditional Chinese medicine additive for promoting lactation of sows according to claim 4, wherein the effective viable count of the probiotic is more than or equal to 200 hundred million/g.
6. The additive of claim 3, wherein the fermentation medium comprises glucose, vitamin B, folic acid and lysine.
7. The traditional Chinese medicine additive for promoting lactation of sows as claimed in claim 6, wherein the content of lysine in the fermentation medium is not less than 12.5%.
8. The preparation method of the traditional Chinese medicine additive for promoting lactation of sows as claimed in any one of claims 1 to 7, which is characterized by comprising the following steps:
1) weighing motherwort, Chinese angelica, radix astragali preparata, uniflower swisscentaury root, cluster mallow fruit, cyperus rotundus, salvia miltiorrhiza and epimedium in corresponding parts by weight for later use;
2) mixing the weighed components, pouring the mixture into a grinder for shearing and grinding, then pouring the ground material into a fermentation medium for uniformly mixing, inoculating probiotic bacteria, and fermenting for 24-48 h to obtain a liquid fermentation water aqua;
3) drying the prepared liquid fermentation water agent to obtain a solid fermentation agent;
4) adding soybean isoflavone 0.1 wt% into the solid fermentation agent, and mixing to obtain the Chinese medicinal additive.
9. The method for preparing the traditional Chinese medicine additive for promoting lactation of sows according to claim 8, wherein the fermentation temperature in the step 2) is 36-38 ℃.
10. The method for preparing the traditional Chinese medicine additive for promoting lactation of sows according to claim 8, wherein a spray dryer is adopted to dry the liquid fermented water in the step 3).
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104920787A (en) * | 2015-06-02 | 2015-09-23 | 山东宝来利来生物工程股份有限公司 | Probiotic traditional Chinese medicine compound preparation for promoting lactation of sows and improving milk quality |
| CN105106313A (en) * | 2015-09-23 | 2015-12-02 | 福建神农后人生物科技有限公司 | Chinese herbal medicine preparation for enhancing lactation and reproduction functions of sows |
| CN106581360A (en) * | 2016-11-04 | 2017-04-26 | 湖北博大生物股份有限公司 | Probiotic fermented Chinese herbal medicine compound preparation for improving milk quality of sows and preparation method thereof |
| CN106942553A (en) * | 2017-03-27 | 2017-07-14 | 漯河食品职业学院 | A kind of postpartum lactation-promoting health-care beverage and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104920787A (en) * | 2015-06-02 | 2015-09-23 | 山东宝来利来生物工程股份有限公司 | Probiotic traditional Chinese medicine compound preparation for promoting lactation of sows and improving milk quality |
| CN105106313A (en) * | 2015-09-23 | 2015-12-02 | 福建神农后人生物科技有限公司 | Chinese herbal medicine preparation for enhancing lactation and reproduction functions of sows |
| CN106581360A (en) * | 2016-11-04 | 2017-04-26 | 湖北博大生物股份有限公司 | Probiotic fermented Chinese herbal medicine compound preparation for improving milk quality of sows and preparation method thereof |
| CN106942553A (en) * | 2017-03-27 | 2017-07-14 | 漯河食品职业学院 | A kind of postpartum lactation-promoting health-care beverage and preparation method thereof |
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