CN112842946A - Cosmetic composition verified to have nerve soothing effect through electroencephalogram and preparation method thereof - Google Patents

Cosmetic composition verified to have nerve soothing effect through electroencephalogram and preparation method thereof Download PDF

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CN112842946A
CN112842946A CN202110312368.1A CN202110312368A CN112842946A CN 112842946 A CN112842946 A CN 112842946A CN 202110312368 A CN202110312368 A CN 202110312368A CN 112842946 A CN112842946 A CN 112842946A
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extract
cosmetic composition
nerve soothing
nerve
mask
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周紫燕
郭苗
周正
郭阳
张金龙
杨帆
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Hubei Maishite Biotechnology Co Ltd
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The invention discloses a cosmetic composition with a nerve soothing effect verified by an electroencephalogram method and a preparation method thereof. The cosmetic composition comprises the following components in percentage by weight: 1.0-30.0% of multiple-relieving functional component, 5.0-40.0% of emollient, 0.5-30.0% of emulsifier, 0.5-20.0% of filler, 0.1-10.0% of thickener, 0.3-5.0% of preservative, 0.05-0.5% of EDTA-2NA, 0.01-1.0% of daily essence and the balance of deionized water. The nerve soothing functional components comprise: phytosterol/octyldodecanol lauroyl glutamate, vitamin E0.1-3.0%; sea sludge extract 0.1-5.6%; 0.1-7.6% of the cactus stem extract; hamamelis virginiana extract 0.1-2%; 0.1-5% of aloe vera leaf extract. The cosmetic composition disclosed by the invention has a nerve soothing effect as verified by an electroencephalogram method. The electroencephalogram feedback condition of the mask product in the use of a consumer is tested, and meanwhile, the subjective evaluation and heart rate evaluation data of the consumer are integrated.

Description

Cosmetic composition verified to have nerve soothing effect through electroencephalogram and preparation method thereof
Technical Field
The invention relates to a cosmetic composition, belongs to the technical field of daily chemicals, and particularly relates to a cosmetic composition with a nerve soothing effect verified by an electroencephalogram method and a preparation method thereof.
Background
In the field of various skin care products, the efficacy requirements of the product not only improve the skin, but also meet the requirements on pressure and relaxation, the experience feeling of nerve relaxation can be brought to consumers in the process of the product, and the cosmetic composition with the nerve relaxation efficacy and the type of facial mask paper are screened out through evaluation of brain waves of the consumers.
It was found that brain waves (EEG) can help to evaluate and visualize the level of relief and relaxation experienced by the consumer during use of the mask. Electroencephalogram (EEG) is a macroscopic electrophysiological phenomenon expressed by the collective discharge of brain nerve cells in cerebral cortex, and is the most intuitive expression of the activity state of human brain. The study applied brain wave monitoring to brain wave changes during mask application to study the psychological impact of different masks on consumers.
EEG oscillatory activity can be divided into delta rhythms (delta <3Hz), theta rhythms (theta, 3-8 Hz), alpha rhythms (alpha, 8-12 Hz), beta rhythms (beta, 12-30 Hz), and gamma rhythms (gamma, 30-100 Hz). The delta rhythm (delta <3Hz), theta rhythm (theta, 3-8 Hz) are slow wave rhythms that typically occur when people feel relaxed, such as sleep or meditation. The beta rhythm is a fast wave that can be detected when mental concentration, thinking or processing external information, or when a person is excited, anxious or stressed.
Electroencephalogram data of low-frequency theta rhythm (4-7Hz) and high-frequency beta rhythm (14-30Hz) of T0 (1 min before mask application), T1, T4, T7 (0-1 min, 3-4min and 6-7min during mask application) and T10 (2-3 min after mask removal) are respectively extracted.
And through data analysis and integration of the subjective feedback result of the consumer and the heart rate measurement result, defining the ratio of theta/beta as a stress relaxation index. The larger the index, the more relaxed the brain.
The color of the brain map reflects the power of the brain electricity, and the power changes from blue to red from small to large.
Can help solve the difficult problem that technicians in the field are difficult to evaluate the nerve relaxation condition of consumers.
Disclosure of Invention
The invention aims to provide a cosmetic composition with a nerve soothing effect verified by brain wave tests, which can solve stress and achieve the nerve soothing effect and is greatly favored by consumers.
A cosmetic composition with nerve soothing effect comprises the following components in percentage by weight of the total composition:
1.0-30.0% of nerve soothing functional ingredients, which comprises: a composition with a soothing effect for a facial mask is prepared from the following components in percentage by weight:
phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 0.1-3.0%; sea sludge extract 0.1-5%; 0.1-7.6% of stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA); 0.1-2% of Hamamelis virginiana (HAMAMELIS VIRGINIANA) extract; 0.1-5% of leaf extract of Aloe BARBADENSIS (Aloe BARBADENSIS);
Figure BDA0002989896280000021
another object of the present invention is to provide a method for preparing the above cosmetic composition having a nerve soothing effect.
Further, the cosmetic composition with the nerve soothing effect comprises the following components in percentage by weight of the total weight of the composition:
nerve soothing effective component 10.0-30.0%;
the nerve soothing functional ingredients comprise: phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 2-5.0%; 2-11.6% of sea sludge extract; 2-5.6% of stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA); 2-10.5% of Hamamelis virginiana (HAMAMELIS VIRGINIANA) extract; 2-10.5% of leaf extract of Aloe BARBADENSIS (Aloe BARBADENSIS);
Figure BDA0002989896280000022
Figure BDA0002989896280000031
further, according to the cosmetic composition with the nerve soothing effect, the nerve soothing effect component comprises the following raw material components in percentage by weight of the total weight of the composition:
a) phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 0.01-1.0%;
b) sea sludge extract 0.01-1.6%;
c) 0.01-0.6% of stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA);
d) hamamelis virginiana (HAMAMELIS VIRGINIANA) extract 0.01-0.5%;
e) 0.01-0.5% of leaf extract of Aloe BARBADENSIS (Aloe BARBADENSIS).
Further, according to the cosmetic composition with the nerve soothing effect, the nerve soothing effect component comprises the following raw material components in percentage by weight of the total weight of the composition:
a) phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 0.1-1.0%;
b) sea sludge extract 0.1-1.6%;
c) 0.1-0.6% of stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA);
d) hamamelis virginiana (HAMAMELIS VIRGINIANA) extract 0.1-0.5%;
e) 0.1-0.5% of leaf extract of Aloe BARBADENSIS (Aloe BARBADENSIS).
Specifically, in one embodiment, the multiple skin care benefit ingredients are present in an amount selected from 3% to 20%, preferably 5% to 15%.
Further, the cosmetic composition with multiple skin care effects, wherein the emollient is at least one selected from caprylic capric triglyceride, squalane, avocado oil, shea butter, jojoba oil, glycerin, butylene glycol, hexylene glycol, pentylene glycol, polydimethylsiloxane, dimethiconol, PEG-11 methyl ether polydimethylsiloxane, phytosterol/octyldodecyl lauroyl glutamate, hydrogenated polyisobutene, rapeseed oil, polydecene, soybean oil, olive oil, isododecane, isohexadecane, stearyl alcohol, and behenyl alcohol.
Further, the emulsifier is selected from at least one of olive oil PEG-7 esters, PEG-8 caprylic/capric glycerides, sorbitan olive oleate, polysorbate-20, laureth-23, PEG-40 stearate, steareth-21, palmitol and PEG-75 stearate and mixtures of glyceryl stearate and steareth-20, polysorbate-80, soya lecithin PC60, mixtures of glyceryl stearate and PEG-75 stearate, poloxamer 407, PEG-30 dipolyhydroxystearate, ceteareth-25.
Further, the filler is at least one selected from titanium dioxide, mica, boron nitride, polymethylsilsesquioxane, diatomite, kaolin, cellulose acetate, aluminum starch octylsuccinate, talc, barium sulfate and volcanic ash.
Further, the thickener is at least one selected from the group consisting of hydroxyethyl cellulose, xanthan gum, carbomer, acrylic acid (ester)/copolymer, polymer EMT-10, polyacrylate crosspolymer-6, sodium acrylate/sodium acryloyldimethyl taurate copolymer, acrylic acid (ester)/C10-30 alkanol acrylate crosspolymer, acryloyldimethyl taurate/VP copolymer, acrylic acid (ester)/C10-30 alkanol acrylate crosspolymer, polyethylene, and gum arabic. The thickener content is selected from the range of 0.1-10%, preferably from the range of 0.3-8%, and most preferably from 0.5-5%.
Further, the preservative is at least one selected from phenoxyethanol, ethylhexyl glycerol, pentanediol, hexanediol, jasmone, sodium benzoate, triclosan and chlorphenesin.
In addition, the invention also provides a preparation method of the cosmetic with the nerve soothing effect composition, which comprises the following process steps:
1) wetting and completely dispersing the thickening agent in water to obtain a mixed solution;
2) adding nerve soothing functional components, an emollient, a filler, a preservative and EDTA-2NA into the mixed solution obtained in the step 1), heating to 65 ℃, and homogenizing at 3000r/min for 3 minutes to completely disperse the nerve soothing functional components;
3) adding an emulsifier and a daily essence into the step 2), homogenizing at 3000r/min for 3 minutes to completely emulsify the mixture, and heating to 65 ℃ to obtain the cosmetic composition with the nerve soothing effect.
Specifically, the cosmetic with nerve soothing effect composition of the present invention has a pH in the range of 4 to 10, preferably a pH in the range of 5 to 8, and most preferably a pH in the range of 5 to 7.
The cosmetic composition prepared by the preparation method has nerve soothing effect. Nerve soothing efficacy the nerve soothing efficacy was evaluated by electroencephalography (EEG).
Electroencephalogram (EEG) is a macroscopic electrophysiological phenomenon expressed by the collective discharge of brain nerve cells in cerebral cortex, and is the most intuitive expression of the activity state of human brain. The study applied brain wave monitoring to brain wave changes during mask application to study the psychological impact of different masks on consumers.
EEG oscillatory activity can be divided into delta rhythms (delta <3Hz), theta rhythms (theta, 3-8 Hz), alpha rhythms (alpha, 8-12 Hz), beta rhythms (beta, 12-30 Hz), and gamma rhythms (gamma, 30-100 Hz). The delta rhythm (delta <3Hz), theta rhythm (theta, 3-8 Hz) are slow wave rhythms that typically occur when people feel relaxed, such as sleep or meditation. The beta rhythm is a fast wave that can be detected when mental concentration, thinking or processing external information, or when a person is excited, anxious or stressed.
Electroencephalogram data of low-frequency theta rhythm (4-7Hz) and high-frequency beta rhythm (14-30Hz) of T0 (1 min before mask application), T1, T4, T7 (0-1 min, 3-4min and 6-7min during mask application) and T10 (2-3 min after mask removal) are respectively extracted from the electroencephalogram of a subject.
The ratio of θ/β is defined as the stress relaxation index s (x) by data interpretation. The larger the index, the more relaxed the brain.
The color of the brain map reflects the power of the brain electricity, and the power changes from blue to red from small to large.
And the subjective evaluation and the heart rate evaluation of the testee are combined to be used as an evaluation means of the nerve soothing efficacy of the consumers.
Specifically, the cosmetics with nerve soothing effect of the composition of the present invention can be in the form of solvent dispersion or suspension, emulsified particles or polymer coating.
In particular, the cosmetic with nerve soothing effect composition of the present invention is a skin care product, in particular a lotion, essence, cream, eye cream, body lotion, gel, sunscreen lotion.
By means of the technical scheme, the invention has the following advantages and beneficial technical effects:
1) the innovative nerve soothing effect compound component is applied to the cosmetic composition, has a synergistic skin care effect, and has the skin care effect and the nerve soothing effect.
2) The cosmetic composition disclosed by the invention has a nerve soothing effect as verified by an electroencephalogram method. The electroencephalogram feedback condition of the mask product in the use of a consumer is tested, and meanwhile, the subjective evaluation and heart rate evaluation data of the consumer are integrated.
Drawings
FIG. 1 shows EMOTIV
Figure BDA0002989896280000051
A map of electrode locations;
FIG. 2 is a diagram of a test process for a consumer EEG test evaluation method;
FIG. 3 is a graph of test data for low frequency theta rhythms (4-7Hz) for five test products;
FIG. 4 is a graph of test data for high frequency beta rhythm (14-30Hz) for five test products;
FIG. 5 is a cerebro-topographic map of the relaxation indices S (x) for five samples T0, T1, T4, T7, T10;
FIGS. 6(a) and 6(b) are graphs showing the variation of the relaxation exponent S (x) in different sample test groups, respectively;
FIG. 7 is a graph of heart rate for five sample consumers;
fig. 8 is a five mask consumer overall satisfaction score.
Detailed Description
The invention discloses a cosmetic composition with a nerve soothing effect verified by an electroencephalogram (EEG) method and a preparation method thereof. The cosmetic composition comprises 1.0-30.0% of nerve soothing functional component by weight percentage; the nerve soothing functional ingredients comprise: a composition with soothing effect for facial mask is prepared from the following components:
phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 0.1-3.0%;
sea sludge extract 0.1-5%;
0.1-7.6% of stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA);
0.1-2% of Hamamelis virginiana (HAMAMELIS VIRGINIANA) extract;
0.1-5% of leaf extract of Aloe BARBADENSIS (Aloe BARBADENSIS).
The effective nerve soothing component is selected from phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E); sea sludge extract; stem extract of Opuntia STREPTACANTHA (Opuntia STREPTACANTHA); hamamelis virginiana (HAMAMELIS VIRGINIANA) extract; the combination of ALOE BARBADENSIS (ALOE BARBADENSIS) leaf extract and a cosmetically acceptable carrier, through preferred combinations and efficacy testing, has found that the most preferred composition ratios, synergistic skin care efficacy and also nerve soothing efficacy.
The invention tests and verifies the relaxation index of the cosmetic composition by a brain wave EEG method, and adopts electroencephalogram feedback condition of a mask product in consumer use by subjective evaluation of a subject and heart rate evaluation of the subject.
The following are descriptions of the effective components, respectively.
(ii) phytosterol/octyldodecanol lauroyl glutamate
The phytosterol/octyldodecanol lauroyl glutamate is derived from glutamic acid of natural fatty acid and emollient of phytosterol. Research has proved that it can form liquid crystal film like ceramide. Therefore, the skin moistening performance of the skin-moistening lotion can be compared with that of ceramide. It is natural, mild and environment friendly; has the functions of softening and moistening skin and helping the skin to be in a state of relaxing and relaxing.
② tocopherol
The tocopherol helps cells to breathe and remove cell pollutants and the like; promoting blood circulation, promoting red blood cell function, and preventing thrombosis. It is also an antioxidant, which limits oxidative damage to the body. The oxidation process generates free radicals, which, if left uncontrolled, are likely to cause serious degenerative diseases. Antioxidants such as tocopherols can destroy free radicals and prevent or delay physical damage.
③ sludge extract
The silt extract contains various components, can quickly absorb redundant grease of skin, clean and tighten skin pores, relieve the phenomena of large pores and glossy surface, and help to relieve skin pressure.
Extract of cactus
The cactus extract has antibacterial effect, can be used in cosmetics for treating acne caused by high androgen by inhibiting androgen receptor activity. The radix et caulis Opuntiae Dillenii extract has effects of promoting skin growth factor generation, and activating skin, and can be used in anti-aging cosmetics.
Hamamelis virginiana extract
Hamamelis virginiana (HAMAMELIS VIRGINIANA) extract, also known as winter flower, tattoo and spotted alder, is a woodland area where earthy growth occurs in the northeast part of the united states. In late autumn, this unique plant carries delicate gold flowers and pods, which mature one year after the leaves fall, burst and spread the seeds from the mother plant to ensure the next generation. Its branches and bark contain therapeutic and aromatic components and, after distillation, produce the clear, fragrant, natural astringent known to us today.
Indigenous americans recognize the value of witch hazel and apply it topically to treat minor wounds, abrasions, and skin irritation. The heritage supporter of the nineteenth century learned the efficacy of this plant and for the first time commercially produced witch hazel extract as a basic ingredient suitable for use in various personal care products.
The use of witch hazel has been outside the skin care range because it is a mild and effective astringent. Other uses include hair care, eye washes, eye drops, mouth washes, and personal hygiene products. Witch hazel is considered a natural, soothing and cost-effective plant ingredient by both consumers and medical professionals. Witch hazel has many beneficial properties that naturally improve the performance of cosmetics and pharmaceuticals. Excellent sensitive muscle formulations, skin protectants, astringents, anti-irritants, treatments, irritations and discomforts due to minor cuts, abrasions and insect bites. Relieving itching, burning and swelling of fibrous tissue, repairing sensitive skin, and removing excessive oil and sebum. Relieving itching, burning and swelling of fibrous tissue, and healing damaged and irritated skin.
Extract of aloe vera leaf
Aloe BARBADENSIS (Aloe BARBADENSIS) leaf extract, wherein the ALOE is succulent plant with water content of more than 90%. The aloe water is rich in micromolecular organic acid, micromolecular saccharides, amino acid and partial trace elements. According to the research, when the aloe water flows along the pipe wall in the human body, the flow speed is twice as fast as that of the common water, so that the effective components in the product can be quickly absorbed, and the efficacy is improved.
The present invention is illustrated by the following examples, which are provided for the purpose of further illustration only and are not intended to limit the scope of the present invention. Other insubstantial modifications and adaptations of the present invention can be made without departing from the scope of the present invention. Unless otherwise specified, the following percentages (%) are mass percentages.
Example 1
A cosmetic composition with nerve soothing effect is prepared into a facial mask, wherein the contents of the raw material components of examples 1-4 and the raw material components of comparative example 1 are shown in the following Table 1.
Table 1 raw material component ratios (unit: mass%) of examples 1 to 4 and comparative example 1
Figure BDA0002989896280000071
Figure BDA0002989896280000081
The preparation process flow of the whitening and spot-fading cream in the embodiments 1-4 of the invention is as follows:
1) sequentially adding the phase A raw materials into a main tank, and stirring and dispersing completely;
2) slowly adding each B phase powder, homogenizing at 3000r/min for 3min, and determining complete dispersion;
3) sequentially adding C-phase grease, heating to 65 ℃, and stirring until the grease is completely dissolved;
4) sequentially adding the D-phase raw materials, emulsifying, and homogenizing at 3000r/min for 3 min;
5) cooling to below 50 deg.C, sequentially adding phase E, and adjusting pH to 6.0;
6) cooling to 30 ℃, filtering by 100 meshes and discharging.
Wherein, based on the total weight of the composition, examples 1-4 of the nerve soothing composition formulation of component D consist of, as shown in Table 2 below:
table 2 nerve soothing composition formulations examples 1-4 (% by weight)
Figure BDA0002989896280000082
Figure BDA0002989896280000091
The following is a content of the effect verification test example section.
1. Brain wave testing
Test samples: example 1
A 256Hz emottiv EPOC wearable brain wave sampler for recording brain wave (EEG) signals, the conductive solution being saline, the wireless EEG signal system consisting of 14 EEG signals according to the international 10-20 system, as shown in fig. 1. The heart rate of the experimenter was monitored during the test using a Yuwell YX303 pulse detector. The subject lies on the beauty chair to complete the whole test, the whole process closes eyes, does not need body movement, the test environment is quiet, the light is soft, the temperature is 22 +/-2 ℃, and the humidity is 55 +/-5%.
Prior to starting the experiment, the subjects were asked to clean their face and sit still for 20 minutes to acclimatize. After the subjects donned the device, they closed their eyes and lay down on a beauty chair for testing. During the test, subjects were asked to minimize swallowing, blinking, and other movements. The experimental environment is quiet and comfortable, and the activities of related personnel are reduced, as shown in figure 2.
Ensure that the subject is not disturbed. The staff helps the subject to apply and remove the mask. The entire brain wave test procedure is about 30 minutes as shown in fig. 3. The heart rate variation of the subject was recorded when the brain wave was tested. After collection of the EEG signals, subjects were asked to subjectively assess the use of the mask during the test. Each subject required testing of three different masks over several days.
The brain wave is an electromagnetic wave having energy. It has been calculated that each activation of a nerve cell produces a small amount of voltage, resulting in a current of approximately 1 milliamp. The power of the EEG is the square of the tiny voltage generated by the activation of these nerve cells.
As shown in fig. 4-6, EEG data of 5 samples of 12 subjects tested were analyzed, and EEG data of α (4-7Hz) and β (14-30Hz) bands of T0 (1 minute before mask application), T1, T4, and T7 (0-1 minute, 3-4 minutes, 6-7 minutes, and T10 (2-3 minutes after mask removal) were extracted for application of the mask to analyze EEG changes of subjects before mask application, at the beginning of mask application, during mask application, after mask application, and after mask removal.
To visualize and synthesize the neurophysiological changes of the subjects over five durations and compare the impact of different masks on the psychological relaxation of the consumers, the experiment defines the power of the α/β ratio as the relaxation index s (x). Relaxation exponent s (x) algorithm:
S(x)=Power(α)/Power(β);
s (x) represents the degree of relaxation of the subject when the mask is applied. Mean of 12 subjects brains.
The topography is plotted against the relaxation indices s (x) for each channel (fig. 6). The color of the brain terrain reflects the relaxation index of the electroencephalogram. The change in power from blue to red means the relaxation index.
Therein, example information is shown in table 3 below.
TABLE 3 detailed expressions and corresponding codes for different packet formulation systems
Grouping Details of Code
Soothing formula
672
Different formulation systems High viscosity formulations 961
(graphite mask cloth) Formula of emulsifying system 368
Using the brain wave evaluation method described previously, the relaxation index s (x) was obtained from the extracted data for the duration before and after the mask was used (T0, T1, T4, T7), plotted for different mask formulations. As shown in fig. 7(a) and 7(b), the results indicate that as time increases after application of the mask, the relaxation index also increases, with 672 being the best, and increasing most significantly over time, indicating that the 672 formula group has a better relaxation effect than the other two groups of formula 368 and formula 961.
In the 672-formula group, a nerve soothing composition was added. The relaxation index s (x) is also higher after use of the mask and after removal of the mask (T1, T4, T7, T7) than before use of the mask (T0). Indicating that the relaxation of the mask was sustained.
2. Consumer heart rate test evaluation
Using a Yuwell YX303 pulse detector to monitor subject heart rate, studies have shown that when people are excited, their heartbeats accelerate, and when they are resting and relaxing, their heartbeats slow. On this basis, the heart rate of T0 was subtracted from each other's duration to obtain the variation in heart rate, and then the variation in heart rate from T1-T7 was averaged to obtain heart rate test data, as shown in FIG. 8. The heart rate decreased, which means that the mask was used to lower the heart rate, and the heart rate decreased more significantly in the 672 and 543 mask formula samples, indicating that the subject was more relaxed.
3. Consumer subjective assessment test
To further confirm the subjective feeling of the subjects using the mask, the subjects were asked to evaluate the overall satisfaction of the mask after the electroencephalogram test was completed. The satisfaction ranged from 1-9 points, very satisfactory was 9 points, particularly unsatisfactory 1 point, overall satisfaction of the subject, as shown in figure 8, highest overall satisfaction was 672, followed by 543 and 728.
In keeping with the brain wave evaluation results and the heart rate results of the previous application examples 1-3, it is shown that the evaluation method can verify that the nerves of the subject are relaxed and the subject feels more comfortable and relaxed during the use of the mask.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.

Claims (9)

1. A cosmetic composition with nerve soothing effect verified by electroencephalography is characterized in that: the cosmetic composition comprises the following components in percentage by weight based on the total weight of the composition:
1.0-30.0% of nerve soothing functional ingredients, which comprises: phytosterol/octyldodecanol lauroyl glutamate, vitamin E0.1-3.0%; sea sludge extract 0.1-5%; 0.1-7.6% of the cactus stem extract; hamamelis virginiana extract 0.1-2%; 0.1-5% of aloe vera leaf extract;
Figure FDA0002989896270000011
2. the cosmetic composition with nerve soothing effect as claimed in claim 1, wherein: the cosmetic composition is composed of the following components by weight:
10.0-30.0% of nerve soothing functional ingredients, which comprises: phytosterol/octyldodecanol lauroyl glutamate, vitamin E2-2.0%; 2-3% of sea sludge extract; 2-5% of the prickly pear stem extract; 2-1% of Hamamelis virginiana extract; 2-4% of aloe vera leaf extract;
Figure FDA0002989896270000012
3. cosmetic composition with a neuro-soothing effect according to claim 1 or 2, characterized in that: the nerve soothing functional component comprises the following raw material components in percentage by weight based on the total weight of the composition:
a) phytosterol/octyldodecanol lauroyl glutamate, vitamin E0.5-1.0%;
b) sea sludge extract 0.5-1.5%;
c) 0.5-1.0% of the cactus stem extract;
d) hamamelis virginiana extract 0.1-0.5%;
e) 0.5-2% of aloe vera leaf extract.
4. A cosmetic composition with nerve soothing effect as claimed in claim 3, wherein: the nerve soothing functional component comprises the following raw material components in percentage by weight based on the total weight of the composition:
a) phytosterol/octyldodecanol lauroyl glutamate, tocopherol (vitamin E) 1.0%;
b) 1.0% of sea sludge extract;
c) 0.6 percent of the cactus stem extract;
d) hamamelis virginiana extract 0.5%;
e) aloe barbadensis leaf extract 0.5%.
5. The cosmetic composition with nerve soothing effect as claimed in claim 1, wherein:
the emollient is selected from at least one of caprylic capric triglyceride, squalane, avocado oil, shea butter, jojoba oil, glycerol, butanediol, hexanediol, pentanediol, polydimethylsiloxane, dimethiconol, PEG-11 methyl ether polydimethylsiloxane, phytosterol/octyl dodecyl lauroyl glutamic acid, hydrogenated polyisobutene, rapeseed oil, polydecene, soybean oil, olive oil, isododecane, isohexadecane, stearyl alcohol, and behenyl alcohol;
the emulsifier is selected from at least one of olive oil PEG-7 esters, PEG-8 caprylic/capric glycerides, sorbitan olive oleate, polysorbate-20, laureth-23, PEG-40 stearate, steareth-21, palmitol and PEG-75 stearate and mixtures of glyceryl stearate and steareth-20, polysorbate-80, soya lecithin PC60, mixtures of glyceryl stearate and PEG-75 stearate, poloxamer 407, PEG-30 dipolyhydroxystearate, ceteareth-25;
the filler is selected from at least one of titanium dioxide, mica, boron nitride, polymethylsilsesquioxane, diatomite, kaolin, cellulose acetate, aluminum starch octylsuccinate, talcum powder, barium sulfate and volcanic ash;
the thickening agent is selected from at least one of hydroxyethyl cellulose, xanthan gum, carbomer, acrylic acid (ester)/copolymer, polymer EMT-10, polyacrylate cross-linked polymer-6, sodium acrylate/sodium acryloyldimethyl taurate copolymer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, acryloyldimethyl taurate/VP copolymer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, polyethylene and gum arabic;
the preservative is at least one selected from phenoxyethanol, ethylhexyl glycerol, pentanediol, hexanediol, jasmone, sodium benzoate, triclosan and chlorphenesin.
6. A process for the preparation of a cosmetic composition with a neuro-soothing effect according to any of claims 1 to 5, characterized in that it comprises the following process steps:
1) wetting and completely dispersing the thickening agent in water to obtain a mixed solution;
2) adding nerve soothing functional components, an emollient, a filler, a preservative and EDTA-2NA into the mixed solution obtained in the step 1), heating to 65 ℃, and homogenizing at 3000r/min for 3 minutes to completely disperse the nerve soothing functional components;
3) adding an emulsifier and a daily essence into the step 2), homogenizing at 3000r/min for 3 minutes to completely emulsify the mixture, and heating to 65 ℃ to obtain the cosmetic composition with the nerve soothing effect.
7. A cosmetic characterized by: the cosmetic comprises the cosmetic composition prepared by the preparation method of claim 6, and has nerve soothing effect; nerve soothing efficacy the nerve soothing efficacy was evaluated by electroencephalography (EEG);
EEG oscillatory activity can be divided into delta rhythms (delta <3Hz), theta rhythms (theta, 3-8 Hz), alpha rhythms (alpha, 8-12 Hz), beta rhythms (beta, 12-30 Hz), and gamma rhythms (gamma, 30-100 Hz);
the delta rhythm (delta <3Hz), the theta rhythm (theta, 3-8 Hz) are slow wave rhythms that typically occur when people feel relaxed, such as sleep or meditation;
beta rhythm is a fast wave that can be detected when mental concentration, thinking, or processing external information, or when a person is excited, anxious, or stressed;
respectively extracting electroencephalogram data of low-frequency theta rhythm (4-7Hz) and high-frequency beta rhythm (14-30Hz) of T0 (1 min before mask application), T1, T4, T7 (0-1 min, 3-4min and 6-7min during mask application) and T10 (2-3 min after mask removal) from the electroencephalogram of a subject;
defining the ratio of theta/beta as a stress relaxation index S (x) through data analysis; the larger the index, the more relaxed the brain;
the color of the brain map reflects the power of the brain electricity, and the power changes from blue to red from small to large; and the subjective evaluation and the heart rate evaluation of the testee are combined to be used as an evaluation means of the nerve soothing efficacy of the consumers.
8. The cosmetic of claim 7, wherein: the cosmetic is in a solvent dispersion or suspension mode, or in the form of emulsified particles, or in a polymer-coated mode; the selected mask cloth is graphene mask cloth, separated mask cloth or ultrathin mask cloth.
9. The cosmetic of claim 7, wherein: the cosmetic is facial mask; the cosmetic composition can be applied to skin cream, skin lotion, skin gel, skin essence, skin lotion, eye cream, body lotion, gel or sunscreen lotion.
CN202110312368.1A 2021-03-24 2021-03-24 Cosmetic composition verified to have nerve soothing effect through electroencephalogram and preparation method thereof Pending CN112842946A (en)

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Application publication date: 20210528