CN112791156A - 仔猪传染性胃肠炎防治的药物组合物、制备方法和应用 - Google Patents
仔猪传染性胃肠炎防治的药物组合物、制备方法和应用 Download PDFInfo
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- CN112791156A CN112791156A CN202110261970.7A CN202110261970A CN112791156A CN 112791156 A CN112791156 A CN 112791156A CN 202110261970 A CN202110261970 A CN 202110261970A CN 112791156 A CN112791156 A CN 112791156A
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Abstract
本发明属于药物制备技术领域,公开了一种仔猪传染性胃肠炎防治的药物组合物、制备方法和应用,所述仔猪传染性胃肠炎防治的药物组合物按照质量份数计,由百合6~8份、蒲公英3~5份、补骨脂3~5份、石榴皮2~4份、苍术2~3份、苦参2~4份、天名精1~2份、吴茱萸3~6份、大青叶1~3份、大枣1~2份、白术2~3份、荆芥1~2份、巴戟天1~3份、藿香1~2份、竹茹2~5份、山楂2~3份、金银花2~3份、楮实子3~4份、水20~30份组成。本发明以清热解毒,燥湿止泻并用,兼以调畅气机,祛除表邪,表里兼治,增强免疫力,提高饲养效益;药物组合物可以掺杂在饲料中进行饲喂,适口性好,无刺激气味,方便进行仔猪喂养。
Description
技术领域
本发明属于药物制备技术领域,尤其涉及一种仔猪传染性胃肠炎防治的药物组合物、制备方法和应用。
背景技术
目前,猪传染性胃肠炎是由冠状病毒科、冠状病毒属的猪传染性胃肠炎病毒引起的一种高度接触性肠道疾病。以呕吐、严重腹泻、脱水为特征。发病季节性明显,多发于寒冷的冬、春季节,各年龄的猪都易感,以两周龄内的新生仔猪死亡率最高,几乎可达100%,超过5周龄则死亡率低,但仔猪即使康复后多发育不良,生长迟缓,生产性能下降,饲料报酬率低,给养猪业造成了较大的经济损失。
目前,本病在全国有的地方有流行的趋势,并常和其他细菌混合感染,给养猪业造成严重危害。就临床所见,2周龄以内的仔猪感染后12~24小时出现呕吐,继而出现严重的水样或糊状腹泻,粪便呈黄色,常夹有未消化的凝乳块,恶臭。体重迅速下降,仔猪明显脱水,多在发病后的2~7天死亡,死亡率达100%;在2~3周龄的仔猪,死亡率在0~10%。断乳猪感染后2~4天发病,表现水泻,呈喷射状,粪便呈灰色或褐色,个别猪呕吐,在5~8天后腹泻停止,极少死亡,但体重下降,常表现发育不良,成为僵猪。有些母猪与患病仔猪密切接触反复感染,症状较重,体温升高,泌乳停止,呕吐、食欲不振和腹泻,也有些哺乳母猪不表现临诊症状。本病病理剖检可见胃内充满乳凝块、胃底黏膜充血、出血,浆膜出血;小肠鼓气,小肠壁可见弥漫性充血、出血,肠壁变薄呈半透明状,内充满水样粪便,肠系膜淋巴结充血、肿胀。病猪消瘦,脱水明显。
对仔猪传染性胃肠炎的治疗,目前在临床上多是采用西药,虽然能暂时延缓病情,但效果并不理想,且要投入大批资金,降低养猪效益。
通过上述分析,现有技术存在的问题及缺陷为:对仔猪传染性胃肠炎的治疗,目前在临床上多是采用西药,虽然能暂时延缓病情,但效果并不理想,且要投入大批资金,降低养猪效益。
发明内容
针对现有技术存在的问题,本发明提供了一种仔猪传染性胃肠炎防治的药物组合物、制备方法和应用。
本发明是这样实现的,一种仔猪传染性胃肠炎防治的药物组合物的制备方法,所述仔猪传染性胃肠炎防治的药物组合物的制备方法包括以下步骤:
步骤一,进行药材的预处理:按照质量份数称取百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、吴茱萸、大青叶、大枣、白术、荆芥、巴戟天、藿香、竹茹、山楂、金银花、楮实子作为药物组合物制备的药材原料;将所述药材分别置于清水中,对药材进行清洗,将清洗后的药材表面水分沥干,得到处理后的药材;
步骤二,对药材进行煎煮得到药物混合液:将处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子置于砂锅中,加入清水进行浸泡;将药材连同浸泡液进行煎煮,过滤保留滤液,得到第一次煎煮液;向滤渣中加水进行煎煮,过滤保留滤液,得到第二次煎煮液;将第一次煎煮液与第二次煎煮液混合,静置,去除底部沉淀,保留上清液即为药物混合液;
步骤三,进行大青叶的处理得到大青叶提取物:将大青叶在烘干箱中摊平,对大青叶进行烘干得到干燥的大青叶;将干燥的大青叶进行粉碎并将粉碎的大青叶置于研磨机中研磨,过筛,得到大青叶粉末;将大青叶粉末置于回流提取装置中,加入乙醇进行回流提取,得到提取液;对提取液进行加热,挥发乙醇,得到大青叶提取物;
步骤四,对山楂进行处理得到山楂提取物:将山楂的果核与果肉分离,得到山楂果核与山楂果肉;对山楂果肉加水进行煎煮,得到山楂果核煎煮液;对山楂果核煎煮液进行减压浓缩得到山楂果核浓缩液;将山楂果肉置于破壁机中进行打浆得到山楂浆液;将山楂浆液进行过筛,去除粒径大于1mm的山楂颗粒;过筛后,将山楂果核浓缩液与山楂浆液进行混合,搅拌均匀后超声分散,得到山楂提取物;
步骤五,使用吴茱萸进行吴茱萸提取物的制备:将吴茱萸置于粉碎机中粉碎得到吴茱萸粗粉;将吴茱萸粗粉与乙醇进行混合,超声提取,提取次数为3~5次,得到提取液;将提取液进行减压过滤,合并滤液;将滤液进行浓缩蒸干,并对蒸干物进行粉碎、研磨,得到吴茱萸提取物;
步骤六,进行仔猪传染性胃肠炎防治的药物组合物的制备:将药物混合液置于浓缩机中进行加热浓缩,得到混合浓缩液;在搅拌机中加入混合浓缩液、大青叶提取物、山楂提取物、吴茱萸提取物,搅拌均匀,得到药物共混液;将药物共混液进行冷冻干燥,并对干燥产物进行粉碎,得到仔猪传染性胃肠炎防治的药物组合物。
进一步,步骤二中,所述浸泡的时间为5~8h。
进一步,步骤二中,所述静置的时间为20~50min。
进一步,步骤三中,所述烘干的温度为50~65℃,烘干的时间为40~60min。
进一步,步骤三中,所述乙醇的体积浓度为65~75%。
进一步,步骤四中,所述山楂果核浓缩液的密度为1.1~1.2g/cm3。
进一步,步骤五中,所述超声提取的频率为50~60kHz,超声的时间为20~30min。
进一步,步骤六中,所述冷冻干燥的温度为-40~-20℃。
本发明的另一目的在于提供一种应用所述的仔猪传染性胃肠炎防治的药物组合物的制备方法制备得到的仔猪传染性胃肠炎防治的药物组合物,其特征在于,所述仔猪传染性胃肠炎防治的药物组合物按照质量份数计,由百合6~8份、蒲公英3~5份、补骨脂3~5份、石榴皮2~4份、苍术2~3份、苦参2~4份、天名精1~2份、吴茱萸3~6份、大青叶1~3份、大枣1~2份、白术2~3份、荆芥1~2份、巴戟天1~3份、藿香1~2份、竹茹2~5份、山楂2~3份、金银花2~3份、楮实子3~4份、水20~30份组成。
本发明的另一目的在于提供一种所述的仔猪传染性胃肠炎防治的药物组合物在预防和治疗仔猪传染性胃肠炎和猪流行性腹泻中的应用。
结合上述的所有技术方案,本发明所具备的优点及积极效果为:本发明提供的仔猪传染性胃肠炎防治的药物组合物,以清热解毒,燥湿止泻并用,兼以调畅气机,祛除表邪,表里兼治。通过药材的有机组合,辩证配伍和相互辅佐,增强了药物组合物清热燥湿止泻的功效,从而达到治愈仔猪传染性胃肠炎的目的。通过科学配伍能更有效地防治仔猪传染性胃肠炎,治疗功效好且安全无毒,增强动物的免疫力,提高饲养效益。本发明提供的仔猪传染性胃肠炎防治的药物组合物可以掺杂在饲料中进行饲喂,适口性号,无刺激气味,方便使用。
附图说明
为了更清楚地说明本申请实施例的技术方案,下面将对本申请实施例中所需要使用的附图做简单的介绍,显而易见地,下面所描述的附图仅仅是本申请的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下还可以根据这些附图获得其他的附图。
图1是本发明实施例提供的仔猪传染性胃肠炎防治的药物组合物的制备方法流程图。
图2是本发明实施例提供的对处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子进行煎煮得到药物混合液的方法流程图。
图3是本发明实施例提供的使用干燥的大青叶制备大青叶粉末,回流提取,得到大青叶提取物的方法流程图。
图4是本发明实施例提供的将山楂的果核与果肉分离,分别对山楂果核与山楂果肉进行处理得到山楂提取物的方法流程图。
图5是本发明实施例提供的使用吴茱萸进行吴茱萸提取物制备的方法流程图。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。
针对现有技术存在的问题,本发明提供了一种仔猪传染性胃肠炎防治的药物组合物、制备方法和应用,下面结合附图对本发明作详细的描述。
本发明实施例提供的仔猪传染性胃肠炎防治的药物组合物按照质量份数计,由百合6~8份、蒲公英3~5份、补骨脂3~5份、石榴皮2~4份、苍术2~3份、苦参2~4份、天名精1~2份、吴茱萸3~6份、大青叶1~3份、大枣1~2份、白术2~3份、荆芥1~2份、巴戟天1~3份、藿香1~2份、竹茹2~5份、山楂2~3份、金银花2~3份、楮实子3~4份、水20~30份组成。
如图1所示,本发明实施例提供的仔猪传染性胃肠炎防治的药物组合物的制备方法包括以下步骤:
S101,进行百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、吴茱萸、大青叶、大枣、白术、荆芥、巴戟天、藿香、竹茹、山楂、金银花、楮实子的预处理,得到处理后的药材;
S102,对处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子进行煎煮得到药物混合液;
S103,使用干燥的大青叶制备大青叶粉末,回流提取,得到大青叶提取物;
S104,将山楂的果核与果肉分离,分别对山楂果核与山楂果肉进行处理得到山楂提取物;
S105,使用吴茱萸进行吴茱萸提取物的制备;
S106,进行仔猪传染性胃肠炎防治的药物组合物的制备。
本发明实施例提供的进行百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、吴茱萸、大青叶、大枣、白术、荆芥、巴戟天、藿香、竹茹、山楂、金银花、楮实子的预处理,得到处理后的药材,包括:按照质量份数称取百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、吴茱萸、大青叶、大枣、白术、荆芥、巴戟天、藿香、竹茹、山楂、金银花、楮实子作为药物组合物制备的药材原料;将所述药材分别置于清水中,对药材进行清洗,将清洗后的药材表面水分沥干,得到处理后的药材。
如图2所示,对处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子进行煎煮得到药物混合液,包括:
S201,将处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子置于砂锅中,加入清水进行浸泡;
S202,将药材连同浸泡液进行煎煮,过滤保留滤液,得到第一次煎煮液;
S203,向滤渣中加水进行煎煮,过滤保留滤液,得到第二次煎煮液;
S204,将第一次煎煮液与第二次煎煮液混合,静置,去除底部沉淀,保留上清液即为药物混合液。
本发明实施例提供的浸泡的时间为5~8h。
本发明实施例提供的静置的时间为20~50min。
如图3所示,本发明实施例提供的使用干燥的大青叶制备大青叶粉末,回流提取,得到大青叶提取物,包括:
S301,将大青叶在烘干箱中摊平,对大青叶进行烘干得到干燥的大青叶;
S302,将干燥的大青叶进行粉碎并将粉碎的大青叶置于研磨机中研磨,过筛,得到大青叶粉末;
S303,将大青叶粉末置于回流提取装置中,加入乙醇进行回流提取,得到提取液;
S304,对提取液进行加热,挥发乙醇,得到大青叶提取物。
本发明实施例提供的烘干的温度为50~65℃,烘干的时间为40~60min。
本发明实施例提供的乙醇的体积浓度为65~75%。
如图4所示,本发明实施例提供的将山楂的果核与果肉分离,分别对山楂果核与山楂果肉进行处理得到山楂提取物,包括:
S401,将山楂的果核与果肉分离,得到山楂果核与山楂果肉;
S402,对山楂果肉加水进行煎煮,得到山楂果核煎煮液;对山楂果核煎煮液进行减压浓缩得到山楂果核浓缩液;
S403,将山楂果肉置于破壁机中进行打浆得到山楂浆液;
S404,将山楂果核浓缩液与山楂浆液进行混合,搅拌均匀后超声分散,得到山楂提取物。
本发明实施例提供的山楂果核浓缩液的密度为1.1~1.2g/cm3。
本发明实施例提供的将山楂果肉置于破壁机中进行打浆得到山楂浆液,好包括:将山楂浆液进行过筛,去除粒径大于1mm的山楂颗粒。
如图5所示,本发明实施例提供的使用吴茱萸进行吴茱萸提取物的制备,包括:
S501,将吴茱萸置于粉碎机中粉碎得到吴茱萸粗粉;
S502,将吴茱萸粗粉与乙醇进行混合,超声提取,提取次数为3~5次,得到提取液;
S503,将提取液进行减压过滤,合并滤液;
S504,将滤液进行浓缩蒸干,并对蒸干物进行粉碎、研磨,得到吴茱萸提取物。
本发明实施例提供的超声提取的频率为50~60kHz,超声的时间为20~30min。
本发明实施例提供的进行仔猪传染性胃肠炎防治的药物组合物的制备,包括:将药物混合液置于浓缩机中进行加热浓缩,得到混合浓缩液;在搅拌机中加入混合浓缩液、大青叶提取物、山楂提取物、吴茱萸提取物,搅拌均匀,得到药物共混液;将药物共混液进行冷冻干燥,并对干燥产物进行粉碎,得到仔猪传染性胃肠炎防治的药物组合物。
本发明实施例提供的冷冻干燥的温度为-40~-20℃。
下面结合药理学分析对本发明作进一步描述。
百合,具有养阴润肺,清心安神之功效。常用于阴虚燥咳,劳嗽咳血,虚烦惊悸,失眠多梦,精神恍惚。
蒲公英,性味苦、甘,寒。归肝、胃经。功能主治清热解毒,消肿散结,利尿通淋。用于疔疮肿毒,乳痈,瘰疠,目赤,咽痛,肺痈,肠痈,湿热黄疸,热淋涩痛。
补骨脂,性温,味辛、苦。归肾经、脾经。温肾助阳、纳气、止泻。属补虚药下属分类的补阳药。用治肾阳不足、命门火衰之腰膝冷痛、阳痿、遗精、尿频、脾肾阳虚泄泻、肾不纳气之虚喘、白癜风等。
石榴皮,味酸、涩,性寒。治日久水泻,煨砂糖吃。治久痢脓血、大肠下血。根,走经络。
苍术,性味辛、苦,温。归脾、胃、肝经。功能主治燥湿健脾,祛风散寒,明目。用于脘腹胀满,泄泻,水肿,脚气痿躄,风湿痹痛,风寒感冒,夜盲。
苦参,有清热燥湿,杀虫,利尿之功。用于热痢,便血,黄疸尿闭,赤白带下,阴肿阴痒,湿疹,湿疮,皮肤瘙痒,疥癣麻风,外治滴虫性阴道炎。
天名精,性味味苦;辛;性寒归肚;肺;功能主治清热;化痰;解毒;杀虫;破瘀;止血。主乳蛾、喉痹、急慢惊风、牙痛、疔疮肿毒、痔瘘、皮肤痒疹;毒蛇咬伤;虫积;血瘕;吐血;衄血;血淋;创伤出血。
吴茱萸,性味辛、苦,热;有小毒。归肝、脾、胃、肾经。功能主治散寒止痛,降逆止呕,助阳止泻。用于厥阴头痛,寒疝腹痛,寒湿脚气,经行腹痛,脘腹胀痛,呕吐吞酸,五更泄泻,外治口疮;高血压。
大青叶,性味苦,寒。归心、胃经。功能主治清热解毒,凉血消斑。用于温邪入营,高热神昏,发斑发疹,黄疸,热痢,痄腮,喉痹,丹毒,痈肿。
大枣,性味甘,温。归脾、胃经。功能主治补中益气,养血安神。用于脾虚食少,乏力便溏,妇人脏躁。
白术,性味苦、甘,温。归脾、胃经。功能主治健脾益气,燥湿利水,止汗,安胎。用于脾虚食少,腹胀泄泻,痰饮眩悸,水肿,自汗,胎动不安。土白术健脾,和胃,安胎。用于脾虚食少,泄泻便溏,胎动不安。
荆芥,性味辛,微温。归肺、肝经。功能主治解表散风,透疹。用于感冒,头痛,麻疹,风疹,疮疡初起。炒炭治便血,崩漏,产后血晕。
巴戟天,性味甘,辛,微温。归肾、肝经。功能主治补肾阳,强筋骨,祛风湿。用于阳痿遗精,宫冷不孕,月经不调,少腹冷痛,风湿痹痛,筋骨痿软。
藿香,性味味辛;性微温归肺;脾;胃经功能主治祛暑解表;化湿和胃。主夏令感冒;寒热头痛;胸脘痞闷;呕吐泄泻;妊娠呕吐;鼻渊;手;足癣。
竹茹,性味性微寒,味甘。功能主治清热化痰,除烦止呕。
山楂,性味酸、甘、微温。归脾、胃、肝经。功能主治消食健胃,行气散瘀。用于肉食积滞,胃脘胀满,泻痢腹痛,瘀血经闭,产后瘀阻,心腹刺痛,疝气疼痛;高脂血症。焦山楂消食导滞作用增强。用于肉食积滞,泻痢不爽。
金银花,性味性平,味甘,气香。功能主治镇惊,祛风,败毒。
楮实子,性味甘,寒。归肝、肾经。功能主治补肾清肝,明目,利尿。用于腰膝酸软,虚劳骨蒸,头晕目昏,目生翳膜,水肿胀满。
在本发明的描述中,除非另有说明,“多个”的含义是两个或两个以上;术语“上”、“下”、“左”、“右”、“内”、“外”、“前端”、“后端”、“头部”、“尾部”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。此外,术语“第一”、“第二”、“第三”等仅用于描述目的,而不能理解为指示或暗示相对重要性。
以上所述,仅为本发明的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,都应涵盖在本发明的保护范围之内。
Claims (10)
1.一种仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,所述仔猪传染性胃肠炎防治的药物组合物的制备方法包括以下步骤:
步骤一,进行药材的预处理:按照质量份数称取百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、吴茱萸、大青叶、大枣、白术、荆芥、巴戟天、藿香、竹茹、山楂、金银花、楮实子作为药物组合物制备的药材原料;将所述药材分别置于清水中,对药材进行清洗,将清洗后的药材表面水分沥干,得到处理后的药材;
步骤二,对药材进行煎煮得到药物混合液:将处理后的百合、蒲公英、补骨脂、石榴皮、苍术、苦参、天名精、大枣、白术、荆芥、巴戟天、藿香、竹茹、金银花、楮实子置于砂锅中,加入清水进行浸泡;将药材连同浸泡液进行煎煮,过滤保留滤液,得到第一次煎煮液;向滤渣中加水进行煎煮,过滤保留滤液,得到第二次煎煮液;将第一次煎煮液与第二次煎煮液混合,静置,去除底部沉淀,保留上清液即为药物混合液;
步骤三,进行大青叶的处理得到大青叶提取物:将大青叶在烘干箱中摊平,对大青叶进行烘干得到干燥的大青叶;将干燥的大青叶进行粉碎并将粉碎的大青叶置于研磨机中研磨,过筛,得到大青叶粉末;将大青叶粉末置于回流提取装置中,加入乙醇进行回流提取,得到提取液;对提取液进行加热,挥发乙醇,得到大青叶提取物;
步骤四,对山楂进行处理得到山楂提取物:将山楂的果核与果肉分离,得到山楂果核与山楂果肉;对山楂果肉加水进行煎煮,得到山楂果核煎煮液;对山楂果核煎煮液进行减压浓缩得到山楂果核浓缩液;将山楂果肉置于破壁机中进行打浆得到山楂浆液;将山楂浆液进行过筛,去除粒径大于1mm的山楂颗粒;过筛后,将山楂果核浓缩液与山楂浆液进行混合,搅拌均匀后超声分散,得到山楂提取物;
步骤五,使用吴茱萸进行吴茱萸提取物的制备:将吴茱萸置于粉碎机中粉碎得到吴茱萸粗粉;将吴茱萸粗粉与乙醇进行混合,超声提取,提取次数为3~5次,得到提取液;将提取液进行减压过滤,合并滤液;将滤液进行浓缩蒸干,并对蒸干物进行粉碎、研磨,得到吴茱萸提取物;
步骤六,进行仔猪传染性胃肠炎防治的药物组合物的制备:将药物混合液置于浓缩机中进行加热浓缩,得到混合浓缩液;在搅拌机中加入混合浓缩液、大青叶提取物、山楂提取物、吴茱萸提取物,搅拌均匀,得到药物共混液;将药物共混液进行冷冻干燥,并对干燥产物进行粉碎,得到仔猪传染性胃肠炎防治的药物组合物。
2.如权利要求1所述得仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤二中,所述浸泡的时间为5~8h。
3.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤二中,所述静置的时间为20~50min。
4.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤三中,所述烘干的温度为50~65℃,烘干的时间为40~60min。
5.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤三中,所述乙醇的体积浓度为65~75%。
6.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤四中,所述山楂果核浓缩液的密度为1.1~1.2g/cm3。
7.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤五中,所述超声提取的频率为50~60kHz,超声的时间为20~30min。
8.如权利要求1所述的仔猪传染性胃肠炎防治的药物组合物的制备方法,其特征在于,步骤六中,所述冷冻干燥的温度为-40~-20℃。
9.一种应用如权利要求1~8任意一项所述的仔猪传染性胃肠炎防治的药物组合物的制备方法制备得到的仔猪传染性胃肠炎防治的药物组合物,其特征在于,所述仔猪传染性胃肠炎防治的药物组合物按照质量份数计,由百合6~8份、蒲公英3~5份、补骨脂3~5份、石榴皮2~4份、苍术2~3份、苦参2~4份、天名精1~2份、吴茱萸3~6份、大青叶1~3份、大枣1~2份、白术2~3份、荆芥1~2份、巴戟天1~3份、藿香1~2份、竹茹2~5份、山楂2~3份、金银花2~3份、楮实子3~4份、水20~30份组成。
10.一种如权利要求9所述的仔猪传染性胃肠炎防治的药物组合物在预防和治疗仔猪传染性胃肠炎和猪流行性腹泻中的应用。
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