CN112748072A - Full-automatic urine iodine blood iodine detection machine and automatic detection method thereof - Google Patents
Full-automatic urine iodine blood iodine detection machine and automatic detection method thereof Download PDFInfo
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- CN112748072A CN112748072A CN202011616517.5A CN202011616517A CN112748072A CN 112748072 A CN112748072 A CN 112748072A CN 202011616517 A CN202011616517 A CN 202011616517A CN 112748072 A CN112748072 A CN 112748072A
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- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 title claims abstract description 67
- 239000011630 iodine Substances 0.000 title claims abstract description 67
- 229910052740 iodine Inorganic materials 0.000 title claims abstract description 67
- 210000002700 urine Anatomy 0.000 title claims abstract description 28
- 238000001514 detection method Methods 0.000 title claims abstract description 27
- 239000008280 blood Substances 0.000 title claims abstract description 23
- 210000004369 blood Anatomy 0.000 title claims abstract description 23
- 230000005540 biological transmission Effects 0.000 claims abstract description 79
- 238000012546 transfer Methods 0.000 claims abstract description 25
- 238000012163 sequencing technique Methods 0.000 claims abstract description 19
- 230000007246 mechanism Effects 0.000 claims description 46
- 238000007599 discharging Methods 0.000 claims description 17
- 230000033001 locomotion Effects 0.000 claims description 10
- 238000012360 testing method Methods 0.000 claims description 7
- 238000005192 partition Methods 0.000 claims description 4
- 238000005070 sampling Methods 0.000 claims description 4
- 230000002485 urinary effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 2
- 238000012545 processing Methods 0.000 abstract description 2
- 206010067997 Iodine deficiency Diseases 0.000 description 6
- 230000009471 action Effects 0.000 description 6
- 235000006479 iodine deficiency Nutrition 0.000 description 6
- 238000012544 monitoring process Methods 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 201000006347 Intellectual Disability Diseases 0.000 description 2
- TUFLVBXBZSNFCZ-UHFFFAOYSA-N arsenic cerium Chemical compound [As].[Ce] TUFLVBXBZSNFCZ-UHFFFAOYSA-N 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010012559 Developmental delay Diseases 0.000 description 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 description 1
- DGEZNRSVGBDHLK-UHFFFAOYSA-N [1,10]phenanthroline Chemical compound C1=CN=C2C3=NC=CC=C3C=CC2=C1 DGEZNRSVGBDHLK-UHFFFAOYSA-N 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 239000003150 biochemical marker Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000004641 brain development Effects 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 208000003532 hypothyroidism Diseases 0.000 description 1
- 230000002989 hypothyroidism Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- -1 iodide ions Chemical class 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000006479 redox reaction Methods 0.000 description 1
- 208000002254 stillbirth Diseases 0.000 description 1
- 231100000537 stillbirth Toxicity 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 238000002562 urinalysis Methods 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
- 238000005353 urine analysis Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/13—Moving of cuvettes or solid samples to or from the investigating station
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
According to the full-automatic urine iodine blood iodine detector and the automatic detection method thereof, the cuvette transmission device, the automatic gun head dismounting device, the automatic gun head loading device and the automatic sequencing device are utilized, the transfer device is combined to realize automatic sequencing loading and dismounting of the gun heads and the cuvettes, and in the whole detection process, full-automatic batch processing is realized, manual interference is not needed, the use is convenient and fast, and the efficiency is high.
Description
Technical Field
The invention relates to the technical field of urine iodine blood iodine detection equipment, in particular to a full-automatic urine iodine blood iodine detection machine and an automatic detection method thereof.
Background
In the field of hygiene and medicine, the detection of iodide ions is mainly the detection of urine iodine and water iodine. Urine iodine is an important index for iodine deficiency disease prevention and treatment monitoring and crowd iodine nutrition level evaluation, and is widely adopted at home and abroad. The iodine content in the urine of the crowd can reflect that the iodine intake of the crowd is iodine deficiency, iodine is suitable or iodine is excessive, and the monitoring of the iodine content in the urine of the crowd is an important basis for guiding the crowd to scientifically supplement iodine, so that the iodine content monitoring method has important public health significance. For pregnant women, iodine deficiency may lead to a decrease in maternal-fetal thyroid hormone synthesis, affecting fetal brain development, and leading to a decrease in intelligence. Urine iodine is a biochemical marker for controlling iodine deficiency of pregnant women, and has important significance for evaluating the iodine nutrition condition of the pregnant women. At present, in the existing arsenic-cerium catalytic timing determination method, a urine sample is digested by using a strong oxidant at normal temperature, according to the principle that iodine catalyzes arsenic-cerium redox reaction, an indicator is used for indicating a reaction end point, a stopwatch is used for recording reaction time, and urine iodine content is calculated according to the reaction time.
Urine analysis is one of the most common clinical test indexes, and not only provides reference for the diagnosis and the observation of curative effect of urinary system diseases, but also is very helpful for the diagnosis of other system diseases which can cause the change of blood biochemical components. In addition, urinalysis can also be used for safety medication detection and initial assessment of health status.
The content of iodine in urine is the focus of attention of people in routine detection, is an index for judging the iodine nutrition status of individuals or groups, and is also an epidemiological index for evaluating the degree of iodine deficiency. Iodine is an essential trace element of human body, iodine deficiency can cause abortion, stillbirth, congenital malformation, hypothyroidism, intellectual development disorder, physical development disorder, simple deafness and dumb, and excess iodine can also cause intellectual development disorder.
The existing iodine-enriched blood iodine detection equipment is generally complex in structure and expensive in cost, and ordinary families, social health centers or small clinics are not equipped with the equipment, and due to the complex operation steps, personnel trained professionally can be used for accurately detecting the iodine-enriched blood iodine.
Disclosure of Invention
The invention provides a full-automatic urine iodine and blood iodine detection machine and an automatic detection method thereof, and aims to solve the technical problems of low automation degree, low detection efficiency and high cost caused by the fact that the conventional urine iodine and blood iodine detection feeding depends on manual work.
According to one aspect of the invention, a full-automatic urine iodine blood iodine tester is provided, which comprises a cuvette transmission device, a cuvette conveying device and a cuvette conveying device, wherein the cuvette transmission device is used for realizing automatic conveyance of cuvettes;
the automatic gun head dismounting device is used for automatically dismounting the used gun head;
the automatic gun head loading device is used for automatically conveying the gun heads;
the automatic sample feeding device is used for realizing automatic sample feeding and discharging;
the cuvette transmission device is arranged in parallel with the automatic gun head dismounting device and the automatic gun head loading device, the automatic gun head dismounting device is arranged between the cuvette transmission device and the automatic gun head loading device, and the automatic sample loading device is arranged on one side of the cuvette transmission device;
the automatic sequencing device is used for automatically sequencing the sampling gun heads and the cuvettes, and is provided with two output ends which are respectively arranged adjacent to the cuvette transmission device and the automatic gun head loading device;
and the transfer device is erected above the space between the automatic gun head loading device and the cuvette transmission device and can realize the movement in the directions of the Y axis and the Z axis.
On the basis of the scheme, the cuvette transmission device preferably comprises a transmission ring, a driving wheel and a driven wheel, the transmission ring is sleeved between the driving wheel and the driven wheel, and cards with U-shaped grooves are uniformly arranged on the transmission ring at intervals.
On the basis of the scheme, the automatic sequencing device comprises a hopper, guide grooves and a friction conveying device, a partition plate is arranged in the middle of the hopper to separate the hopper into two containing cavities, the bottom of each containing cavity is inclined, the guide grooves are arranged at the lowest positions of the containing cavities, the guide grooves are respectively opposite to the automatic gun head loading device and the cuvette transmission device, the friction conveying device is arranged on two sides of the two guide grooves, openings are formed in wall plates on one sides, adjacent to the friction conveying device, of the guide grooves, and conveying brushes on the friction conveying device are respectively in friction contact with the gun heads and the cuvettes in the guide grooves.
On the basis of the scheme, the friction conveying device preferably comprises a friction belt, a first wheel and a second wheel, the friction belt is arranged between the first wheel and the second wheel, and the friction belt is provided with a transmission brush.
On the basis of the scheme, the transfer device preferably comprises a support, a guide rail and a transmission head, the support is erected above the automatic gun head loading device and the cuvette transmission device, the guide rail is arranged on the support, the transmission head is slidably arranged on the guide rail and connected with a driving body arranged on the support, a driving cylinder is arranged on the transmission head, and a telescopic rod of the driving cylinder is connected with a chuck.
Preferably on the basis of the scheme, sample automatic feeding device includes rack, conveyer, sets up feed mechanism and unloading mechanism on the rack, the guiding hole has been seted up on the both ends mesa of rack, feed mechanism with unloading mechanism all includes shift fork and driving motor, driving motor's output with the shift fork links to each other, just the top of shift fork is passed the guiding hole can the guiding hole is downthehole to be removed, conveyer sets up and is being close to feed mechanism one side on the rack, conveyer follows the sample frame feed mechanism one side transmits extremely unloading mechanism one side.
Preferably, on the basis of the scheme, a conveying groove is formed in the rack, one side of the conveying groove starts from the shifting fork of the feeding mechanism, the other side of the conveying groove stops at the shifting fork side of the discharging mechanism, and the conveying groove is adjacent to and parallel to the conveying device.
On the basis of the scheme, the conveying device comprises a transmission motor, a screw rod, a nut and a push rod in an L shape, the output end of the transmission motor is connected with the screw rod, the nut is installed on the screw rod, the push rod is connected with the nut, and the output end of the push rod penetrates through the conveying groove to extend upwards.
The invention relates to a full-automatic urine iodine blood iodine automatic detection method, which comprises the following steps,
step S1, the automatic sequencing device automatically sequences the cuvette and the gun head and then respectively transmits the cuvette and the gun head to the automatic loading device;
step S2, the automatic sample feeding device automatically sorts the sample racks to one side of the cuvette transmission device;
step S3, the transfer device moves to the automatic gun head loading device to obtain the gun head, moves to one side of the cuvette transmission device, sucks the sample to be detected from the sample cup on the sample rack, and transfers the sample to the cuvette;
and step S4, the transfer device moves the automatic gun head dismounting device, and after the used gun head is dismounted by the automatic gun head dismounting device, the transfer device moves to the automatic gun head mounting device and enters the next cycle.
According to the full-automatic urine iodine blood iodine detector and the automatic detection method thereof, the cuvette transmission device, the automatic gun head dismounting device, the automatic gun head loading device and the automatic sequencing device are utilized, the transfer device is combined to realize automatic sequencing loading and dismounting of the gun heads and the cuvettes, and in the whole detection process, full-automatic batch processing is realized, manual interference is not needed, the use is convenient and fast, and the efficiency is high.
Drawings
FIG. 1 is a partial enlarged view of the fully automatic iodine in urine blood iodine tester of the present invention;
FIG. 2 is a top view of the fully automatic urine iodine and blood iodine detecting machine of the present invention;
FIG. 3 is a perspective view of the automatic sequencing apparatus of the present invention;
FIG. 4 is a perspective view of another perspective of the automatic sequencing apparatus of the present invention;
FIG. 5 is another perspective view of the automatic sequencing apparatus of the present invention;
FIG. 6 is a perspective view of the automatic sample loading device of the present invention;
FIG. 7 is a perspective view from another perspective of the automatic sample loading apparatus of the present invention;
FIG. 8 is a perspective view of another embodiment of the automatic sample loading device of the present invention;
FIG. 9 is a perspective view from another perspective of another embodiment of an automatic sample loading apparatus of the present invention;
fig. 10 is a detection flow chart of the full-automatic urine iodine and blood iodine detector of the present invention.
Detailed Description
The following detailed description of embodiments of the present invention is provided in connection with the accompanying drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
Referring to fig. 1, and as shown in fig. 2 and fig. 3, the fully automatic urine iodine blood iodine tester of the present invention includes a frame 10, which provides an installation basis for a cuvette transmission device 500, a gun head automatic dismounting device 600, a gun head automatic loading device 700, a test automatic loading device, an automatic sorting device 900, and a transfer device 920;
the cuvette transmission device 500 is used for realizing automatic transmission of cuvettes, the cuvettes are internally provided with reducing agents, phenanthroline solutions and oxidizing agents, and different reagents can be specifically configured according to a test;
the automatic gun head dismounting device 600 is used for automatically dismounting the used gun head, and can automatically dismount and recycle the used gun head, so that the disposable use of the gun head is realized, and the sampling and measuring accuracy is ensured;
the automatic gun head loading device 700 is used for automatically conveying gun heads and automatically loading sterile gun heads so as to realize one-time detection of new gun heads and avoid test confusion from influencing detection accuracy;
the automatic sample feeding device 800 is used for realizing automatic sample feeding and discharging, and conveying sample bottles to be detected to a specified position one by one to realize the purpose of automatic detection;
wherein, the cuvette transmission device 500, the automatic gun head dismounting device 600 and the automatic gun head shelving device 700 are arranged in parallel, the automatic gun head dismounting device 600 is arranged between the cuvette transmission device 500 and the automatic gun head shelving device 700, and the automatic sample feeding device 800 is arranged at one side of the cuvette transmission device 500;
the automatic sequencing device 900 is used for automatically sequencing the sampling gun heads and the cuvettes, two output ends of the automatic sequencing device are respectively arranged adjacent to the cuvette transmission device 500 and the automatic gun head shelving device 700, namely a large number of gun heads and cuvettes are respectively transmitted to the cuvette transmission device 500 and the automatic gun head shelving device 700 after being sequenced by the automatic sequencing device 900, and continuous new cuvettes and gun heads are provided for the cuvette transmission device 500 and the automatic gun head shelving device 700;
and a transfer device 920 which is arranged above the space between the automatic lance head mounting device 700 and the cuvette transmission device 500 and can move in the directions of the Y axis and the Z axis.
As shown in fig. 3, the cuvette conveyer 500 of the present invention comprises a conveying ring 501, a driving wheel 502 and a driven wheel 503, wherein the conveying ring 501 is sleeved between the driving wheel 502 and the driven wheel 503, and the conveying ring 501 is provided with cards 504 having U-shaped grooves at regular intervals. After the cuvettes on the automatic sorting device 900 are automatically sorted and output, the cuvettes are hung on the conveying ring 501 through the U-shaped groove on the card 504, and the conveying ring 501 is used for conveying the cuvettes on the driving wheel 502 and the driven wheel 503, wherein the conveying ring 501 can be a conveying chain or a conveying belt.
The principle of the automatic lance tip mounting device 700 and the automatic lance tip dismounting device 600 according to the present invention is similar to that of the cuvette driving device 500, and therefore, the details thereof are not repeated herein.
Referring to fig. 4, 5 and 6, the automatic sorting apparatus 900 of the present invention includes a hopper 901, a guide groove 904 and a friction conveying apparatus 910, wherein a partition is provided in the middle of the hopper 901 to partition the hopper into two accommodating cavities 903, the bottom of each accommodating cavity 903 is inclined, the guide groove 904 is provided at the lowest position of the accommodating cavity 903, the guide groove 904 is respectively disposed opposite to the automatic tip loading apparatus 700 and the cuvette driving apparatus 500, the friction conveying apparatus 910 is disposed at two sides of the two guide grooves 904, an opening 905 is provided on a side wall plate of the guide groove 904 adjacent to the friction conveying apparatus 910, and a conveying brush 911 on the friction conveying apparatus 910 is respectively in friction contact with the tips and the cuvettes in the guide grooves 904.
During the use, place aseptic cuvette and rifle head in two holding chambeies 903 according to the classification, utilize the slope column structure of holding chamber 903 bottom, combine the action of gravity of cuvette and rifle head, get into the guide way 904, cuvette and rifle head are under the effect of friction conveyer 910, with cuvette and rifle head transmission output to on cuvette transmission 500 and the automatic device 700 of putting on the shelf of rifle head.
In order to prevent the bridge head and the cuvette from being stacked in the guide slot 904 and affecting the transmission, the present invention further comprises a window 915 on the hopper 901, the window 915 is disposed on the upper portion of the opening 905, a support 916 is disposed on one side of the friction conveying device 910, a pusher 918 is disposed on the top of the support 916, the pusher 918 is slidably disposed on the window 915, the bottom of the support 916 is slidably disposed on the linear rail 917, and the linear rail 917 is disposed on the frame 10.
When the friction conveyer 910 is started, the screw rod electric cylinder or air cylinder can be used to drive the support 916 to move on the linear guide 917 in advance, so as to realize the left-right movement of the support 916 along the window 915, so that the tip or cuvette stacked on the guide groove 904 can be removed by using the push head 918, and the tip or cuvette output by the guide groove 904 can be ensured to be output in a single direction.
The hopper 901 of the invention is formed by enclosing side plates and a bottom plate, the bottom plate can be formed by a conveying chain plate, the side plates are arranged on two sides of the conveying chain plate, the conveying chain plate is driven by a driving chain wheel and a driven chain wheel, a baffle plate is arranged on the conveying chain plate, each grid conveying chain plate, the baffle plate and the side plates form a cavity, the gun heads or the colorimetric cups are accommodated in the cavities, and when a motor drives the driving chain wheel to rotate, the colorimetric cups or the gun heads in the cavities are continuously conveyed into the guide grooves 904, so that the automatic conveying is realized.
Of course, the present invention may also arrange a vibration motor at the bottom of the hopper 901 to increase the automatic sorting speed.
It should be noted that the friction conveying device 910 of the present invention includes a friction belt 912, a first wheel 913 and a second wheel 914, the friction belt 912 is installed between the first wheel 913 and the second wheel 914, and the friction belt 912 is installed with a plurality of driving brushes, which are installed on the friction belt 912 at regular intervals. It is noted that the friction belt 912 may be implemented by other structures such as a transmission chain.
The transfer device 920 comprises a support 921, a guide rail 922 and a transmission head 923, wherein the support 921 is arranged at two ends of the automatic gun head loading device 700 and the cuvette transmission device 500, the guide rail 922 is arranged between the two supports 921, the length of the guide rail 922 is greater than the distance between the automatic gun head loading device 700 and the cuvette transmission device 500, the transmission head 923 is slidably arranged on the guide rail 922 and connected with a driving body 924 arranged on the support 921, the transmission head 923 is provided with a driving cylinder, and a telescopic rod of the driving cylinder is connected with a chuck, which is specifically shown in the structural diagram 2.
During the use, driving body 924 orders about transmission head 923 and moves on guided way 922, realizes the transfer of transmission head 923 between rifle head automatic dismounting device 600, cell transmission device 500, the automatic device 700 of putting on shelf of rifle head to utilize the driving cylinder to drive the dop up-and-down motion, thereby realize putting on shelf the action of rifle head, dismantlement and cell.
The driving body 924 of the present invention may be a transmission chain or a transmission belt, and the motor drives the wheel body to move, so as to drive the transmission chain or the transmission belt to move, and connect the transmission head 923 with the transmission chain or the transmission belt, so as to implement the movement of the transmission head 923 on the guide rail 922.
As shown in fig. 7, 8 and 9, the automatic sample feeding device 800 of the present invention includes a rack 100, a conveying device 200, a feeding mechanism 300 and a discharging mechanism 400, which are disposed on the rack 100, wherein two guide holes 101 disposed at intervals are disposed on a left end table of the rack 100, and two guide holes 101 disposed at intervals are disposed on a right end table of the rack 100.
The feeding mechanism 300 and the discharging mechanism 400 of the invention both comprise a shifting fork 310 and a driving motor 311, the output end of the driving motor 311 is connected with the shifting fork 310, the top of the shifting fork 310 passes through the guide hole 101, and the shifting fork 310 can move in the guide hole 101, wherein the feeding mechanism 300 is arranged at the right end of the rack 100, the discharging mechanism 400 is arranged at the left end of the rack 100, the shifting fork 310 of the feeding mechanism 300 is arranged in the guide hole 101 at the right side of the rack 100, and the shifting fork 310 of the discharging mechanism 400 is arranged in the guide hole 101 at the left side of the rack 100. The transfer device 200 of the present invention is provided on the stage 100 on the side close to the loading mechanism 300, and the transfer device 200 transfers the sample rack from the loading mechanism 300 side to the unloading mechanism 400 side.
As shown in fig. 8 and 9, the transferring device 200 of the present invention includes a transferring ring 201 and a driving device 202, the driving device 202 drives the transferring ring 201 to move, a driving lever 203 is disposed on the transferring ring 201, and the driving lever 203 is adapted to the hole on the sample rack. When the automatic feeding device is used, the driving device 202 such as a motor drives the conveying ring 201 to perform annular reciprocating motion between the feeding mechanism 300 and the discharging mechanism 400, and the driving rod 203 is driven to penetrate through a sample rack, so that the sample rack is transmitted to one side of the discharging mechanism 400 from one side of the feeding mechanism 300.
The conveying ring 201 of the present invention may be a transmission belt, such as a V-belt 316, a toothed belt, etc., or a chain, etc., the shift lever 203 is disposed perpendicular to the end surface of the conveying ring 201, when the sample rack pushes the sample rack to the side of the conveying device 200 due to the action of the shift fork 310 on the feeding mechanism 300, the shift lever 203 is inserted into the sample rack, and the sample rack is driven to the side of the blanking mechanism 400 by the movement of the conveying ring 201, thereby completing the automatic transmission.
It should be noted that the rack 100 of the present invention is provided with a conveying groove 204, one side of the conveying groove 204 is set up from the fork 310 of the feeding mechanism 300, the other side of the conveying groove 204 is stopped at the fork 310 of the blanking mechanism 400, and the conveying groove 204 is adjacent to and parallel to the conveying device 200. The guide movement of the sample holder can be realized by the action of the transfer slot 204.
As another preferred embodiment of the present invention, the conveying device 200 of the present invention comprises a transmission motor 205, a lead screw 206, a nut 207 and a push rod 208 in an L shape, wherein an output end of the transmission motor 205 is connected to the lead screw 206, the nut 207 is mounted on the lead screw 206, the push rod 208 is connected to the nut 207, and an output end of the push rod 208 extends upward through the conveying groove 204.
When the screw rod 206 is rotated by the driving motor 205, the nut 207 moves on the screw rod 206 to drive the push rod 208 to push the sample rack in the transfer slot 204 to move from the loading mechanism 300 side to the unloading mechanism 400 side.
As shown in fig. 1, two guide holes 101 are provided for the feeding mechanism 300 and the discharging mechanism 400, respectively, the fork 310 is arranged in a Y shape, and two sides of the two guide holes 101 corresponding to the feeding mechanism 300 and the discharging mechanism 400 are provided with the material blocking plates 102, so that the sample rack can be prevented from swinging in the transverse direction to affect the transmission accuracy thereof under the action of the material blocking plates 102.
The feeding mechanism 300 of the present invention comprises a V-shaped belt 316, a driving wheel 311 and a driven wheel 312, wherein the V-shaped belt 316 surrounds between the driving wheel 311 and the driven wheel 312, the bottom of a shifting fork 310 is slidably mounted on a linear guide 314 through a sliding seat 313, and the sliding seat 313 is connected with the V-shaped belt 316 through a connecting plate 315.
The connecting plate 315 is U-shaped on the side connected to the V-shaped belt 316, and the inner side of the U-shaped is provided with a latch adapted to the V-shaped belt 316.
When the sample rack shifting device is used, the driving body 924 is used for driving the driving wheel 311 to move, the connecting plate 315 is driven to move under the action of the V-shaped belt 316, the connecting plate 315 is pulled to drive the sliding base 313 to convey on the linear guide rail 314, the rotary motion is converted into the linear motion, and the shifting fork 310 on the sliding base 313 shifts the sample rack.
Referring to fig. 10, a fully automatic urine iodine and blood iodine automatic detection method of the present invention includes the following steps,
step S1, the automatic sequencing device 900 automatically sequences the cuvettes and the tips and then respectively transmits the sequences to the cuvette transmission device 500 and the tip automatic shelving device 700;
step S2, the automatic sample feeding device 800 automatically sorts the sample racks to one side of the cuvette driving device 500;
step S3, moving the transfer device 920 to the automatic gun head loading device 700 to obtain the gun heads, moving the gun heads to one side of the cuvette transmission device 500, sucking the samples to be detected from the sample cups on the sample racks, and transferring the samples to be detected to the cuvettes;
in step S4, the transfer device 920 moves the automatic lance tip dismounting device 600, and after the used lance tip is dismounted by the automatic lance tip dismounting device 600, the transfer device 920 moves to the automatic lance tip mounting device 700 and enters the next cycle.
Finally, the method of the present application is only a preferred embodiment and is not intended to limit the scope of the present invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. A full-automatic urine iodine blood iodine detecting machine is characterized by comprising,
the cuvette transmission device is used for realizing the automatic transmission of the cuvette;
the automatic gun head dismounting device is used for automatically dismounting the used gun head;
the automatic gun head loading device is used for automatically conveying the gun heads;
the automatic sample feeding device is used for realizing automatic sample feeding and discharging;
the cuvette transmission device is arranged in parallel with the automatic gun head dismounting device and the automatic gun head loading device, the automatic gun head dismounting device is arranged between the cuvette transmission device and the automatic gun head loading device, and the automatic sample loading device is arranged on one side of the cuvette transmission device;
the automatic sequencing device is used for automatically sequencing the sampling gun heads and the cuvettes, and is provided with two output ends which are respectively arranged adjacent to the cuvette transmission device and the automatic gun head loading device;
and the transfer device is erected above the space between the automatic gun head loading device and the cuvette transmission device and can realize the movement in the directions of the Y axis and the Z axis.
2. The automatic urine iodine blood iodine detecting machine as claimed in claim 1, wherein said cuvette driving unit includes a transmission ring, a driving wheel and a driven wheel, said transmission ring is sleeved between said driving wheel and said driven wheel, and said transmission ring is provided with a plurality of cards having U-shaped slots at regular intervals.
3. The automatic urine iodine blood iodine tester as claimed in claim 1, wherein said automatic sorting device comprises a hopper, a guiding groove and a friction transferring device, a partition board is provided in the middle of said hopper to separate two receiving chambers, the bottom of each receiving chamber is inclined, said guiding groove is provided at the lowest position of said receiving chamber, said guiding groove is respectively opposite to said automatic gun head mounting device and said cuvette driving device, said friction transferring device is provided at two sides of said two guiding grooves, and an opening is provided on a side wall plate of said guiding groove adjacent to said friction transferring device, and a transferring brush on said friction transferring device is respectively in friction contact with said gun head and cuvette in said guiding groove.
4. The automatic iodine testing machine as claimed in claim 3, wherein said friction transferring means comprises a friction belt, a first wheel and a second wheel, said friction belt is installed between said first wheel and said second wheel, and said friction belt is installed with a driving brush.
5. The automatic urine iodine blood iodine detecting machine as claimed in claim 1, wherein said transferring means includes a frame, a guide rail and a driving head, said frame is mounted above said automatic tip mounting means and said cuvette driving means, said guide rail is mounted on said frame, said driving head is slidably mounted on said guide rail and connected to a driving body mounted on said frame, said driving head is provided with a driving cylinder, and a chuck is connected to a telescopic rod of said driving cylinder.
6. The automatic iodine blood iodine detecting machine according to claim 1, wherein said automatic sample feeding device comprises a rack, a transmission device, a feeding mechanism and a discharging mechanism, said feeding mechanism and said discharging mechanism are disposed on said rack, said rack has guide holes on two end faces, said feeding mechanism and said discharging mechanism each comprise a fork and a driving motor, said driving motor has an output end connected to said fork, and the top of said fork passes through said guide hole and can move in said guide hole, said transmission device is disposed on said rack near one side of said feeding mechanism, said transmission device transmits a sample rack from one side of said feeding mechanism to one side of said discharging mechanism.
7. The automatic iodine testing machine for urinary iodine according to claim 6 wherein said rack is provided with a transferring slot, one side of said transferring slot is from said fork of said feeding mechanism, the other side of said transferring slot is at said fork of said discharging mechanism, and said transferring slot is adjacent to and parallel to said transferring device.
8. The automatic iodine testing machine as claimed in claim 7 wherein said transmission means comprises a transmission motor, a lead screw, a nut and a push rod in L shape, wherein the output end of said transmission motor is connected to said lead screw, said nut is mounted on said lead screw, said push rod is connected to said nut, and the output end of said push rod passes through said transmission slot and extends upward.
9. A full-automatic detection method of iodine in urine is characterized by comprising the following steps,
step S1, the automatic sequencing device automatically sequences the cuvette and the gun head and then respectively transmits the cuvette and the gun head to the automatic loading device;
step S2, the automatic sample feeding device automatically sorts the sample racks to one side of the cuvette transmission device;
step S3, the transfer device moves to the automatic gun head loading device to obtain the gun head, moves to one side of the cuvette transmission device, sucks the sample to be detected from the sample cup on the sample rack, and transfers the sample to the cuvette;
and step S4, the transfer device moves the automatic gun head dismounting device, and after the used gun head is dismounted by the automatic gun head dismounting device, the transfer device moves to the automatic gun head mounting device and enters the next cycle.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202011616517.5A CN112748072A (en) | 2020-12-31 | 2020-12-31 | Full-automatic urine iodine blood iodine detection machine and automatic detection method thereof |
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| CN202011616517.5A CN112748072A (en) | 2020-12-31 | 2020-12-31 | Full-automatic urine iodine blood iodine detection machine and automatic detection method thereof |
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Cited By (1)
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| CN114797641A (en) * | 2022-04-21 | 2022-07-29 | 深圳市瑞吉生物科技有限公司 | Dispensing and transferring machine |
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