CN112705282B

CN112705282B - Combined platform and detection device applying same

Info

Publication number: CN112705282B
Application number: CN201911026134.XA
Authority: CN
Inventors: 孙磊林; 陈泽华; 黄立平; 余利; 陈文�; 李骏杨; 刘卓; 李开金
Original assignee: MGI Tech Co Ltd
Current assignee: MGI Tech Co Ltd
Priority date: 2019-10-25
Filing date: 2019-10-25
Publication date: 2023-05-02
Anticipated expiration: 2039-10-25
Also published as: CN112705282A

Abstract

The invention provides a combined platform and a detection device applying the combined platform, wherein the combined platform comprises a lower seat and an upper seat arranged on the lower seat, a first clamping device is arranged between the lower seat and the upper seat, a pushing mechanism capable of moving towards the first clamping device and moving away from the first clamping device is arranged on the lower seat, and the pushing mechanism moves the upper seat in the process of moving towards the first clamping device so that the first clamping device clamps the upper seat on the lower seat, thereby fixing the upper seat on the lower seat. By applying the invention, the process of installing and detaching the upper seat and the tool required to be used are simplified, and the efficiency is improved.

Description

Combined platform and detection device applying same

Technical Field

The invention relates to the field of biochemical substance analysis, in particular to a combined platform and a detection device using the combined platform.

Background

Most biochemical substance analysis instruments (such as gene sequencers) in the market at present adopt a sample carrier (such as a sequencing chip) to bear a sample, after the sample in the sample carrier has a biochemical reaction on a reaction platform, the sample carrier is placed on a detection platform, and the sample in the sample carrier is detected to obtain a certain biological characteristic of the sample. The existing detection platform usually adopts a vacuum adsorption mode to adsorb a sample carrier, if the detection platform is polluted or other conditions affecting adsorption or detection exist, relevant parts of the detection platform need to be detached for cleaning, checking or repairing, and then the detection platform is installed on the detection platform. In the prior art, the structure for unloading and installing the related parts of the detection platform is complex, and the efficiency of cleaning and maintaining the related parts of the detection platform is affected.

Disclosure of Invention

In view of the foregoing, it is desirable to provide a combination platform and a detection device to solve at least one of the above problems.

In one aspect, a combination platform is provided, the combination platform includes a lower seat and installs in the upper seat on the lower seat, be equipped with first clamping device between lower seat and the upper seat, be equipped with on the lower seat and can be directed against first clamping device removes and can keep away from the pushing mechanism that first clamping device removed, pushing mechanism is in the orientation first clamping device removes the in-process upper seat so that first clamping device will the upper seat block in on the lower seat, thereby fix the upper seat in on the lower seat.

Further, the pushing mechanism provides a withdrawing space for the upper seat to move in the process of being far away from the first clamping device so as to release the clamping device to enable the upper seat to be unloaded from the lower seat.

Further, the first locking device comprises a locking tongue arranged on one of the upper seat and the lower seat, and a locking groove arranged on the other of the upper seat and the lower seat.

Further, a second clamping device is further arranged between the pushing mechanism and the upper seat, and the second clamping device is used for clamping the pushing mechanism and the upper seat in the process that the pushing mechanism pushes the upper seat.

Further, the second clamping device comprises a clamping groove arranged on one of the upper seat and the pushing mechanism and a clamping tongue arranged on the other of the upper seat and the pushing mechanism; and/or the end part of the pushing mechanism is provided with a V-shaped block, and the V-shaped block forms a part of the second clamping device.

Further, a limiting block is arranged on the lower seat and used for limiting the end position of the pushing mechanism in the process that the pushing mechanism moves towards the first clamping device.

Further, a supporting seat is arranged on the lower seat and used for supporting the pushing mechanism, and a guiding mechanism is arranged on the supporting seat so as to guide the pushing mechanism to move towards the first clamping device or move away from the first clamping device.

Further, the guiding mechanism comprises a thread pair formed by threads arranged on the pushing mechanism and threads arranged on the supporting seat.

Further, the combined platform further comprises a base, a plurality of pressing assemblies arranged on the base and used for adjusting the plane parallelism of the lower base, wherein the pressing assemblies provide elastic pressure towards the base for the lower base, the adjusting assemblies provide reverse force opposite to the elastic pressure for the lower base, and the plane parallelism of the lower base is adjusted by adjusting the reverse force.

In still another aspect, a detection device is provided, where the detection device includes the combination platform described above.

According to the combined platform and the detection device provided by the embodiment of the invention, the upper seat is pushed to move by the clamping device and the pushing mechanism, so that the upper seat can be clamped on the lower seat, the purpose of simply and quickly installing the upper seat on the lower seat is achieved, and when the upper seat is dismounted, the upper seat can be simply and quickly dismounted only by moving the pushing mechanism to enable the clamping device to loosen the clamping, the installation and dismounting processes of the upper seat and tools required to be used are simplified, and the efficiency is improved.

Drawings

Fig. 1 is a schematic perspective view of a combination platform according to an embodiment of the invention.

Fig. 2 is a schematic diagram of an application scenario of the combination platform shown in fig. 1.

Fig. 3 is a cross-sectional view taken along line III-III of fig. 1.

Fig. 4 is a cross-sectional view taken along line IV-IV of fig. 1.

Fig. 5 is a cross-sectional view taken along line V-V of fig. 1.

Fig. 6 is a schematic block diagram of a detection device according to an embodiment of the present invention.

The invention will be further described in the following detailed description in conjunction with the above-described figures.

Description of the main reference signs

Combined platform	1、7	Base seat	10
				Floating seat	12	Mounting base	14
Sample carrier	3	Detection instrument	5
				Pushing mechanism	120	Mounting hole	121
Clamping tongue	1211、1201	Bump block	141
				Clamping groove	1411、142	Limiting block	122
V-shaped block	1203、103	V-shaped opening	1204
				Convex part	144	Push rod	1205
Handle	1206	Supporting seat	124
				Screw thread pair	125	Compression assembly	126
Adjusting bolt	1261	Elastic device	1262
				Screw hole	101	Screw rod	1263
Head part	1264	Accommodating cavity	127
				An opening	1271	Bottom part	1273
Through hole	1275	Wave spring	1262a
				Spring cover
	1262b	Adjusting assembly	128
				Screw rod	1281	Nut	1282
Through hole	129	Ball bearing	1283
				Concave part	102、105	Slotted hole	104
Distance piece	130	Blind hole	131
				Distance block	106	Detection device	6

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

It will be understood that when an element is referred to as being "mounted" to another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "or/and" as used herein includes any and all combinations of one or more of the associated listed items.

It is to be understood that the terms "upper," "lower," "inner," "outer," and the like are used in an orientation or positional relationship based on that shown in the drawings, merely to facilitate describing embodiments of the present invention and to simplify the description, and are not intended to indicate or imply that the devices or components referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the invention. The terms "first," "second," and the like are used merely to distinguish objects and do not refer to a particular sequential relationship.

Referring to fig. 1 and 2, fig. 1 is a schematic perspective view of a combination platform according to an embodiment of the invention, and fig. 2 is a schematic view of a sample carrier disposed on the combination platform. The combined platform 1 comprises an upper seat, a lower seat and a base. In the present embodiment, the base, the lower base, and the upper base are respectively named and labeled as a base 10, a floating base 12, and a mounting base 14. Said mounting seat 14 as an upper seat is located at the uppermost end of the combination platform 1 for mounting the sample carrier 3. The base 10 is located at the lowermost end of the combination platform 1 for mounting the combination platform 1 to other devices. A floating seat 12 as a lower seat is located between the mounting seat 14 and the base 10. In this embodiment, the mounting base 14 adsorbs the sample carrier 3 to the mounting base 14 by means of vacuum adsorption, the mounting base 14 is opposite to the detecting instrument 5 for detecting the sample in the sample carrier 3, and after the sample carrier 3 is mounted to the mounting base 14, the detecting instrument 5 can be activated to perform detection of the sample in the sample carrier 3, thereby obtaining the desired biological characteristics of the sample. The mounting base 14 is mounted on the floating base 12, in this embodiment, the mounting base 14 is plate-shaped, and the mounting base 14 is mounted on the floating base 12 in an easy-to-mount and easy-to-detach manner, so that the mounting base 14 is convenient to mount and detach. The upper surface of the mounting seat 14 is provided with grooves capable of generating negative pressure to adsorb the sample carrier 3. The floating seat 12 is floatably mounted on the base 10, and in this embodiment, the floating seat 12 is plate-shaped, and the distance between the different positions of the floating seat 12 and the base 10 can be finely adjusted, so that the height of the different positions of the floating seat 12 and the base 10 can be adjusted, and thus the positions of the mounting seat 14 and the sample carrier 3 on the mounting seat 14 relative to the detecting instrument 5 can be adjusted. For example, if the detecting device 5 includes an objective lens, and the detecting device 5 is used to detect the sample in the sample carrier 3, the sample carrier 3 needs to be located on the focal plane of the objective lens, and at this time, the sample carrier 3 can be located on the focal plane of the objective lens by adjusting the distance between the floating seat 12 and the base 10. The base 10 is flat in this embodiment, and the base 10 may be fixed to other devices to integrally mount the combination platform to the other devices.

Please refer to fig. 3. In the present embodiment, the mount 14 is mounted to the floating mount 12 in a manner that is easy to mount and dismount. In this embodiment, the manner is a locking manner, a first locking device is disposed between the mounting base 14 and the floating base 12, specifically, in this embodiment, a protruding locking tongue is disposed on the floating base 12, and a locking groove for accommodating the locking tongue is disposed on the mounting base 14. The first clamping device is formed by the clamping tongue and the clamping groove, and the mounting seat 14 is fixedly mounted on the floating seat 12 through the matching of the clamping tongue and the clamping groove. Further, in the present embodiment, the floating seat 12 is further provided with a pushing mechanism 120, and the pushing mechanism 120 can push the mounting seat 14 to engage the latch on the floating seat 12 with the slot on the mounting seat 14. Specifically, in this embodiment, the floating seat 12 is provided with a mounting hole 121, and the mounting seat 14 is mounted corresponding to the mounting hole 121. The side wall of the mounting hole 121 protrudes from the latch 1211 toward the center of the hole. The lower end of the mounting seat 14 is provided with a protruding block 141, the protruding block 141 is located in the mounting hole 121, and the protruding block 141 defines a clamping groove 1411 matched with the clamping tongue 1211. In the present embodiment, the bump 141 is an oblique bump, the slot 1411 is disposed between the bump 141 and the bottom of the mounting base 14, and in other embodiments, the slot 1411 may be opened on the bump 141.

The pushing mechanism 120 is provided on the opposite side of the floating mount 12 from the tongue 1211. The pushing mechanism 120 may move toward the tongue 1211 or away from the tongue 1211, and when moving toward the tongue 1211, the pushing mechanism 120 approaches the mount 14 and contacts the mount 14, pushing the mount 14 toward the location of the tongue 1211, and finally snapping the tongue 1211 into the groove 1411, thereby fixing the mount 14 to the floating mount 12. When moving away from the tongue 1211, the pushing mechanism 120 moves away from the mounting base 14, providing a space for the mounting base 14 to withdraw, so that the mounting base 14 can be moved to the space for withdrawing, and the tongue 1211 withdraws from the groove 1411, so that the mounting base 14 can be moved out of the floating base 12, and the mounting base 14 can be removed.

In the present embodiment, a second engaging device is provided between the mounting base 14 and the pushing mechanism 120, specifically, a side of the mounting base 14 facing the pushing mechanism 120 is further provided with a slot 142, and a protrusion 144 facing the pushing mechanism 120 is formed at the lower side of the slot 142. The pushing mechanism 120 is further provided with a catch 1201 towards the mounting seat 14. During the process of pushing the mounting seat 14 to move, the clamping tongue 1201 stretches into the clamping groove 142, and the clamping groove 142 and the clamping tongue 1201 form the second clamping device. Further, in the present embodiment, the floating seat 12 is further provided with a stopper 122, and the stopper 122 is disposed towards the pushing mechanism 120, and defines a movable end position of the pushing mechanism 120 during the movement of the pushing mechanism 120 towards the latch 1211. In the present embodiment, the end of the pushing mechanism 120 facing the mounting base 14 is provided with a V-shaped block 1203, and a V-shaped opening 1204 of the V-shaped block 1203 faces the mounting base 14 and the stopper 122. One of the arms of the V-shaped block 1203 constitutes a catch 1201. During the movement of the pushing mechanism 120 towards the mounting seat 14, the protrusion 144 of the mounting seat 14 located below the clamping groove 142 extends into the V-shaped opening 1204, and the pushing mechanism 120 applies a pushing force on the protrusion 144 to push the mounting seat 14 to move, so that the clamping tongue 1211 is clamped into the clamping groove 1411. When the end position is reached, the stopper 122 also extends into the V-shaped opening 1204 and abuts against the other arm of the V-shaped block 1203, thereby restricting the movement of the pushing mechanism 120. In other embodiments, the stopper 122 may be omitted.

In other embodiments, the arrangement of the latch 1201, the slot 142 and the V-shaped block 1203 may be omitted, and the pushing mechanism 120 may be only required to push the mounting base 14 in the direction towards the latch 1211.

In this embodiment, the pushing mechanism 120 includes a push rod 1205 and a handle 1206, and the handle 1206 is disposed at an end of the push rod 1205 away from the V-shaped block 1203 for a user or other apparatus to operate the pushing mechanism 120 to move. The floating seat 12 is provided with a supporting seat 124, and the supporting seat 124 supports the push rod 1205. In the present embodiment, the push rod 1205 is further coupled to the support base 124 through a screw pair 125. The push rod 1205 is moved in the axial direction of the push rod 1205 by rotating the handle 1206. In other embodiments, the screw pair 125 may be omitted, or other guiding mechanisms, such as guide blocks and guide grooves, may be provided.

By arranging the clamping tongue 1211 on the floating seat 12, arranging the clamping groove 1411 on the mounting seat 14, and arranging the pushing mechanism 120 on the floating seat 12, the clamping tongue can be clamped into the clamping groove 1411 by pushing the mounting seat 14 to move through the pushing mechanism 120, so that the purpose of simply and quickly mounting the mounting seat 14 is achieved, and when the mounting seat 14 is dismounted, the mounting seat 14 can be simply and quickly dismounted by only removing the pushing mechanism 120 and then moving the mounting seat 14 to enable the clamping tongue 1211 to withdraw from the clamping groove 1411. In other embodiments, the locations of the tongue 1211 and the groove 1411 may be interchanged, i.e., the tongue 1211 may be disposed on the mount 14 and the groove 1411 may be disposed on the floating mount 12.

Referring to fig. 4, in the present embodiment, the floating seat 12 is mounted on the base 10 through a plurality of pressing assemblies 126, and the pressing assemblies 126 provide elastic pressure to the floating seat 12 and the base 10. In the present embodiment, the pressing assembly 126 includes an adjusting bolt 1261 and an elastic device 1262. Screw hole 101 is formed in base 10, and adjusting bolt 1261 includes a threaded rod 1263 and a head 1264 disposed at one end of threaded rod 1263. The end of the threaded rod 1263 remote from the head 1264 extends into the threaded bore 101 and is connected to the threaded bore 101, and the head 1264 of the adjusting bolt 1261 is constrained to the floating mount 12 to mount the floating mount 12 to the base 10. The elastic device 1262 has one end abutting against the head 1264 of the adjusting bolt 1261 and the other end abutting against the floating seat 12, and the elastic device 1262 is compressed to provide elastic pressure to the floating seat 12 toward the base 10.

In this embodiment, specifically, the floating seat 12 is provided with a receiving cavity 127 corresponding to the position of the screw hole 101 for receiving the adjusting bolt 1261 and the elastic device 1262, and the receiving cavity 127 has an opening 1271 and a bottom 1273 opposite to the opening 1271. The bottom 1273 is adjacent to the base 10, and the bottom 1273 is provided with a through hole 1275 to allow the end of the screw 1263 to pass through and extend into the screw hole 101. The elastic device 1262 is sleeved outside the screw 1263 of the adjusting bolt 1261, one end of the elastic device 1262 is abutted against the bottom 1273, and the other end is abutted against the head 1264 of the adjusting bolt 1261. In the present embodiment, the elastic device 1262 employs a wave spring 1262a, and a spring cover 1262b is provided at one end of the wave spring 1262a near the head 1264 of the adjusting bolt 1261, and the spring cover 1262b abuts against the head 1264.

In the present embodiment, the number of the pressing assemblies 126 is 3, and the three pressing assemblies 126 are disposed at three different positions on the combining platform 1, and the three positions are not located on the same straight line. Specifically, in the present embodiment, the line connecting the positions of the three pressing members 126 substantially forms an isosceles triangle or an isosceles triangle.

Referring to fig. 5, the floating seat 12 adjusts the relative position between the floating seat 12 and the base 10 through a plurality of adjusting assemblies 128. The adjustment assembly 128 provides a counter force to the floating mount 12 that is opposite to the spring force described above, such that the floating mount 12 is stabilized in a position relative to the base 10 when the spring force and counter force experienced by the floating mount 12 are balanced. The relative position between the floating seat 12 and the base 10 is adjusted by adjusting the opposing force by the adjusting assembly 128, thereby adjusting the planar parallelism of the floating seat 12, the mounting seat 14 and the sample carrier 3.

In this embodiment, the adjusting assemblies 128 are disposed on the floating seat 12, each adjusting assembly 128 includes a screw 1281 and a nut 1282, and the screw 1281 and the nut 1282 are adapted to form a screw pair. The floating seat 12 is provided with a through hole 129, the nut 1282 is embedded in the through hole 129, the screw 1281 is inserted in the nut 1282, and the lower end of the screw 1281 abuts against the base 10. The reverse force applied to the floating seat 12 can be adjusted by rotating the screw 1281, so as to achieve the purpose of fine adjustment of the plane parallelism of the floating seat 12, the mounting seat 14 and the sample carrier. In other embodiments, the nut 1282 may not be provided, and an internal thread adapted to the screw may be directly formed in the through-hole 129.

In the present embodiment, two adjusting assemblies 128 are respectively disposed at opposite ends of the floating seat 12.

In this embodiment, in order to improve the adjustment accuracy of the adjustment assembly 128, the screw 128 abuts against the lower end of the base 10 to provide the ball 1283, so as to reduce the contact area with the base 10.

In the present embodiment, a recess 102 is further provided in the base 10 corresponding to the adjustment unit 128, and the recess 102 cooperates with a ball 1283 at the lower end of the screw 1281 to limit the degree of freedom XY. Specifically, in this embodiment, the base 10 is provided with a V-shaped block 103, the V-shaped block 103 is embedded in a slot 104 formed in the base 10, and the V-shaped block 103 has a V-shaped opening, which is the recess 102.

Referring back to fig. 4, in this embodiment, to determine the basic height between the floating seat 12 and the base 10 during installation, a distance member 130 is also provided on the floating seat 12. The distance piece 130 is embedded on the floating seat 12, the upper end of the distance piece 130 is limited, and the lower end extends out of the floating seat 12 and abuts against the base 10, so that the degree of freedom of the floating seat 12 in the Z direction is limited. In the present embodiment, the floating seat 12 is provided with a blind hole 131, the distance member 130 is embedded in the blind hole 131, and the upper end of the distance member 130 abuts against the top wall of the blind hole 131, so as to be limited. In the present embodiment, a recess 105 is further provided in the base 10 corresponding to the distance member 130, and the recess 105 limits the lower end of the distance member 130. Specifically, in the present embodiment, the base 10 is further provided with a distance block 106, and the distance block 106 is provided with the recess 105. In the present embodiment, the distance members 130 and/or the distance blocks 106 are detachably embedded in the floating seat 12 or the base 10, and the basic height between the floating seat 12 and the base 10 in the Z direction can be changed by replacing the distance members 130 with different heights and/or replacing the distance blocks 106 with different heights during installation.

Referring to fig. 6, a schematic diagram of a detection apparatus according to an embodiment of the present invention is shown, the detection apparatus 6 includes a combination platform 7, and the combination platform 7 may be the combination platform 1 provided in the above embodiment or another combination platform obtained by modifying the combination platform 1.

In summary, according to the combined platform and the detection device provided by the embodiments of the invention, the clamping tongue, the clamping groove and the pushing mechanism are utilized to push the installation seat to move, so that the clamping tongue can be clamped into the clamping groove, the purpose of simply and rapidly installing the installation seat is achieved, and when the installation seat is disassembled, the installation seat is moved only by removing the pushing mechanism, so that the clamping tongue can be withdrawn from the clamping groove, the installation seat can be simply and rapidly disassembled, the installation and disassembly processes of the installation seat and tools required to be used are simplified, and the efficiency is improved. In addition, the combined platform provided by the embodiment of the invention also utilizes the cooperation of the compression assembly and the adjusting assembly, thereby realizing the purpose of stepless adjusting the plane parallelism of the floating seat and the mounting seat.

It will be appreciated by persons skilled in the art that the above embodiments have been provided for the purpose of illustrating the invention and are not to be construed as limiting the invention, and that suitable modifications and variations of the above embodiments are within the scope of the invention as claimed.

Claims

1. The combined platform comprises a lower seat and an upper seat arranged on the lower seat, and is characterized in that a first clamping device is arranged between the lower seat and the upper seat, a pushing mechanism capable of moving towards the first clamping device and moving away from the first clamping device is arranged on the lower seat, the pushing mechanism and the first clamping device are respectively positioned on two opposite sides of the upper seat, the pushing mechanism moves the upper seat in the process of moving towards the first clamping device so that the first clamping device clamps the upper seat on the lower seat, and therefore the upper seat is fixed on the lower seat, and the pushing mechanism provides a withdrawing space for the upper seat to move in the process of moving away from the first clamping device so as to release the first clamping device to unload the upper seat from the lower seat; a second clamping device is further arranged between the pushing mechanism and the upper seat, and comprises a clamping groove arranged on the upper seat and a clamping tongue arranged on the pushing mechanism; the end part of the pushing mechanism is provided with a V-shaped block, and one arm part of the V-shaped block forms the clamping tongue; the upper seat is provided with a protruding portion below the clamping groove, the lower seat is provided with a limiting block, and the protruding portion and the limiting block rapidly extend into the V-shaped opening of the V-shaped block in the moving process of the pushing mechanism towards the first clamping device.

2. The combination platform of claim 1, wherein the first engagement means comprises a tongue disposed on one of the upper seat and the lower seat, and a groove disposed on the other of the upper seat and the lower seat.

3. The combination platform of claim 1, wherein a support base is provided on the lower base for supporting the pushing mechanism, and a guiding mechanism is provided on the support base for guiding the pushing mechanism to move toward the first engaging device or move away from the first engaging device.

4. A combination platform according to claim 3, wherein the guide means comprises a pair of threads formed by the thread provided on the pushing means and the thread provided on the support base.

5. The combination platform of claim 1, further comprising a base, a plurality of hold down assemblies mounted to the base, and a plurality of adjustment assemblies for adjusting the planar parallelism of the lower base, wherein the hold down assemblies provide the lower base with a spring pressure toward the base, and the adjustment assemblies provide the lower base with a counter force opposite the spring pressure, the planar parallelism of the lower base being adjusted by adjusting the counter force.

6. A test device comprising a combination platform according to any one of claims 1-4.