CN112691053A - Formula for repairing and removing scars of burned and scalded skin and preparation method - Google Patents

Formula for repairing and removing scars of burned and scalded skin and preparation method Download PDF

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Publication number
CN112691053A
CN112691053A CN202110085530.0A CN202110085530A CN112691053A CN 112691053 A CN112691053 A CN 112691053A CN 202110085530 A CN202110085530 A CN 202110085530A CN 112691053 A CN112691053 A CN 112691053A
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China
Prior art keywords
oil
insect
repairing
skin
essential oil
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110085530.0A
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Chinese (zh)
Inventor
冯金山
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Guangdong Green Gold Biotechnology Co ltd
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Guangdong Green Gold Biotechnology Co ltd
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Priority to CN202110085530.0A priority Critical patent/CN112691053A/en
Publication of CN112691053A publication Critical patent/CN112691053A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/002—Preparations for repairing the hair, e.g. hair cure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Insects & Arthropods (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a prescription for repairing and removing scars of burned and scalded skin and a manufacturing method thereof, wherein the prescription for repairing and removing scars of burned and scalded skin comprises the following raw materials in parts by weight: tenebrio molitor essential oil: 30-40 g of barley pest essential oil: 30-40 g of hermetia illucens essential oil: 20-30 g. The three insect oils prepared by the invention contain linoleic acid which has repairing effect on burns and scalds, and the special lipid antibacterial peptide in the insect oil has certain antibacterial effect, after the three insect oils are compounded, the fatty acid structures and the contents in the respective oil are complemented, the wound healing can be effectively promoted, the skin can be moistened, and the effects of sterilizing, detumescence and scar removal can be achieved. Meanwhile, the unique skin-friendly and moisturizing properties of the insect oil can also enable dry skin to recover luster and tenderness, and has the anti-aging and moisturizing effects.

Description

Formula for repairing and removing scars of burned and scalded skin and preparation method
Technical Field
The invention relates to the field of skin care, in particular to a repairing and scar-removing formula for burn and scald skin and a manufacturing method thereof.
Background
Scars are local symptoms which are caused by the fact that damage of physical, biological, chemical and other factors acts on skin soft tissues of a human body, cause serious damage of the skin soft tissues and cannot be completely and normally repaired, and the appearance and the function are influenced when the scars are left by replacing and repairing fibrous tissues.
At present, the hemorrhage of people in different degrees in life is repaired by the autoimmunity and the regenerative power of patients, so that the repairing time is long, scars can be left, and the patients are suffered from huge physical pain and mental pain, especially burn and scald, which are difficult to repair.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide a prescription for repairing and removing scars of burned and scalded skin and a manufacturing method thereof.
The invention is realized by the following technical measures, and the raw material components and the raw material quantity ratio required by the scar removing prescription for repairing the skin with burns and scalds are as follows: tenebrio molitor essential oil: 30-40 g of barley pest essential oil: 30-40 g of hermetia illucens essential oil: 20-30 g.
As a preferred mode, the tenebrio molitor essential oil: 35 g, barley pest essential oil: 35 g, hermetia illucens essential oil: 25 g.
As a preferable mode, the manufacturing method is as follows: firstly, respectively separating the yellow mealworms, the barley pests and the hermetia illucens by using a 10-mesh sieve, and drying the separated yellow mealworms, the barley pests and the hermetia illucens by using a microwave oven, wherein the water content is controlled to be 5%; and secondly, respectively crushing the three kinds of insect trunks, weighing the three kinds of insect trunks according to a proportion, pouring the three kinds of insect trunks into a swing type stirrer, fully stirring the three kinds of insect trunks for ten minutes, extracting the tenebrio molitor oil, the barley insect oil and the black soldier fly oil by an aqueous enzymatic method or a supercritical CO2 extraction method, mixing and stirring the three kinds of insect oils uniformly to obtain compound insect oil, and filling the compound insect oil into a sperm oil bottle for sealing and storing.
Preferably, the compound insect oil is preserved for one year in a sealed manner.
Preferably, the proportion of the compound insect oil is adjusted according to the fatty acid structures and contents of the three insects.
In a preferable mode, the yellow mealworms and the barley pests are fed with wheat bran and green vegetables for 30-50 days, and the black soldier flies are bred with bean dregs for 8-15 days.
The invention provides a formulation for repairing and removing scars of burned and scalded skin and a preparation method thereof, wherein the ratio of unsaturated fatty acid in yellow mealworm to unsaturated fatty acid in barley worm is more than 75%, the yellow mealworm to barley worm contains active substances such as special lipid antibacterial peptide, vitamin components and the like, has special antibacterial and anti-inflammatory effects, has strong skin affinity and good moisturizing effect, is rich in linoleic acid, alpha-linolenic acid and gamma-linolenic acid which are necessary for human body but can not be synthesized by the human body, is rich in anti-aging factors, and has strong skin affinity and moisturizing function to enable the human skin to be repaired more quickly and have more obvious repairing effect on new scars;
the black soldier fly oil contains a large amount of lauric acid ester, so that the absorption efficiency of the skin is improved.
The three insect oils contain linoleic acid with a function of repairing burns and scalds, so that after the compound insect oil is formed, the compound insect oil not only has a good moistening effect on skin, but also has the effects of moistening hair scales and keeping the moisture of the hair, and meanwhile, the compound insect oil also has good heat resistance and sun-screening properties for the damage of ultraviolet rays and hot air; the compound insect oil has good hair penetration effect, can deeply moisten hair, and prevents hair from drying and forking; the compound insect oil is used for nursing dry, thick and hard nail edges, can soften nail skins, and enables nails to be tougher and glossy.
Detailed Description
The present invention will be described in further detail with reference to examples.
The prescription for repairing and removing the scars of the burned and scalded skin comprises the following raw materials by weight: tenebrio molitor essential oil: 30-40 g of barley pest essential oil: 30-40 g of hermetia illucens essential oil: 20-30 g. The yellow mealworm and the barley worm have the ratio of unsaturated fatty acid of more than 75 percent, contain specific lipid antibacterial peptide, vitamin components and other active substances, have special antibacterial and anti-inflammatory effects, have strong skin affinity and good moisturizing effect, are rich in linoleic acid, alpha-linolenic acid and gamma-linolenic acid which are necessary for human bodies and cannot be synthesized by the human bodies, are rich in anti-aging factors, and have strong skin affinity and moisturizing function to enable the human skin to be quickly repaired and have obvious repairing effect on new scars; the black soldier fly oil contains a large amount of lauric acid ester, so that the absorption efficiency of the skin is improved.
Tenebrio molitor essential oil: 35 g, barley pest essential oil: 35 g, hermetia illucens essential oil: 25 g; the proportion of the compound insect oil is blended according to the fatty acid structures and the contents of the three insects. According to the invention, the respective proportions are regulated according to the fatty acid structures and the contents of the three insects to obtain the optimal proportion, so that the best repairing effect is achieved.
The manufacturing method comprises the following steps: firstly, respectively separating the yellow mealworms, the barley pests and the hermetia illucens by using a 10-mesh sieve, and drying the separated yellow mealworms, the barley pests and the hermetia illucens by using a microwave oven, wherein the water content is controlled to be 5%; washing the three raw materials, sieving with a 10-mesh sieve, air drying, and oven drying with water content of 5%.
And secondly, respectively crushing the three kinds of insect trunks, weighing the three kinds of insect trunks according to a proportion, pouring the three kinds of insect trunks into a swing type stirrer, fully stirring the three kinds of insect trunks for ten minutes, extracting the tenebrio molitor oil, the barley insect oil and the black soldier fly oil by an aqueous enzymatic method or a supercritical CO2 extraction method, mixing and stirring the three kinds of insect oils uniformly to obtain compound insect oil, and filling the compound insect oil into a sperm oil bottle for sealing and storing. The three dry insect raw materials are respectively crushed, weighed according to the quantity, and then put into a swing type stirrer to be crushed, and are fished up in a crushed powder shape after about ten minutes, plant cell walls are degraded by adopting enzyme to release oil, or the influence of pressure and temperature on the dissolving capacity of a supercritical fluid is utilized, and the two methods ensure that the extracted extract has no residual solvent substances, thereby preventing the existence of harmful substances to human bodies and the pollution to the environment in the extraction process and ensuring the pure naturalness of the raw materials.
The compound insect oil is stored for one year in a sealed mode, the compound insect oil is stored for more than six months in a sealed mode, and the compound insect oil is used up to the best within one year.
The yellow mealworms and the barley pests are fed with wheat bran and green vegetables for 30-50 days, and the black soldier flies are bred with bean dregs for 8-15 days. The wheat bran, the green vegetables and the bean dregs are respectively used to ensure that the yellow mealworms, the barley worms and the black soldier flies have higher nutrient components, so that no unnatural components are extracted when the yellow mealworms, the barley worms and the black soldier flies are prepared into finished products.
The above description is provided for the purpose of promoting understanding of the present invention, but the embodiments of the present invention are not limited to the above examples, and any changes, modifications, substitutions, combinations, and simplifications that do not depart from the spirit of the present invention should be construed as equivalents thereof, and are intended to be included within the scope of the present invention.

Claims (6)

1. The formula for repairing and removing the scars of the burned and scalded skin is characterized in that the formula for repairing and removing the scars of the burned and scalded skin comprises the following raw materials in parts by weight: tenebrio molitor essential oil: 30-40 g of barley pest essential oil: 30-40 g of hermetia illucens essential oil: 20-30 g.
2. The repair scar-removing formulation for burn and scald skin according to claim 1, characterized in that the yellow mealworm essential oil: 35 g, barley pest essential oil: 35 g, hermetia illucens essential oil: 25 g.
3. A preparation method of a formula for repairing and removing scars of burned and scalded skin is characterized by comprising the following steps: firstly, respectively separating the yellow mealworms, the barley pests and the hermetia illucens by using a 10-mesh sieve, and drying the separated yellow mealworms, the barley pests and the hermetia illucens by using a microwave oven, wherein the water content is controlled to be 5%; and secondly, respectively crushing the three kinds of insect trunks, weighing the three kinds of insect trunks according to a proportion, pouring the three kinds of insect trunks into a swing type stirrer, fully stirring the three kinds of insect trunks for ten minutes, extracting the tenebrio molitor oil, the barley insect oil and the black soldier fly oil by an aqueous enzymatic method or a supercritical CO2 extraction method, mixing and stirring the three kinds of insect oils uniformly to obtain compound insect oil, and filling the compound insect oil into a sperm oil bottle for sealing and storing.
4. The skin burn and scald repairing and scar removing formula according to claim 3, wherein the compound insect oil seal has a preservation time of one year.
5. The formula for repairing and removing scars from burn and scald skin as claimed in claim 3, wherein the proportion of said compound insect oil is adjusted according to the fatty acid structure and content of three insects.
6. The skin burn and scald repairing and scar removing formula according to any of claims 1 to 5, wherein the yellow mealworms and the barley pests are fed with wheat bran and green vegetables for 30-50 days, and the black soldier flies are bred with bean dregs for 8-15 days.
CN202110085530.0A 2021-01-22 2021-01-22 Formula for repairing and removing scars of burned and scalded skin and preparation method Pending CN112691053A (en)

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CN202110085530.0A CN112691053A (en) 2021-01-22 2021-01-22 Formula for repairing and removing scars of burned and scalded skin and preparation method

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Application Number Priority Date Filing Date Title
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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101117613A (en) * 2007-09-04 2008-02-06 张均康 Method for extracting tenebrio oil
CN103169814A (en) * 2013-04-07 2013-06-26 重庆涪江生物科技有限公司 Compound essential oil for adjutant therapy of burns and scalds
CN103484240A (en) * 2013-09-16 2014-01-01 中国农业科学院饲料研究所 Barley pest larva cosmetic matrix oil and preparing method thereof
CN104327934A (en) * 2014-06-05 2015-02-04 中北大学 Extraction and refining method of grease from barley pest
CN105456155A (en) * 2015-11-23 2016-04-06 太仓安佑生物科技有限公司 Method for preparing cosmetic raw materials from Hermetia illucens larvas and application of method
CN108283670A (en) * 2018-04-13 2018-07-17 张爱丽 A kind of pharmaceutical composition and preparation method thereof for treating burn and scald
CN108472240A (en) * 2015-11-16 2018-08-31 C·桑端 The skin-protection product of the extract containing black soldier flies
KR20190011054A (en) * 2017-07-24 2019-02-01 계명대학교 산학협력단 Skin external application composition for promoting wound healing or cosmetic composition for improving wrinkle comprising oil of Tenebrio molitor mealworm
CN110938485A (en) * 2018-09-22 2020-03-31 湖北远志黄粉虫养殖有限责任公司 Production method of yellow mealworm oil
CN111165656A (en) * 2020-01-09 2020-05-19 南京大学（溧水）生态环境研究院 Efficient preparation method of hermetia illucens freeze-dried powder

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101117613A (en) * 2007-09-04 2008-02-06 张均康 Method for extracting tenebrio oil
CN103169814A (en) * 2013-04-07 2013-06-26 重庆涪江生物科技有限公司 Compound essential oil for adjutant therapy of burns and scalds
CN103484240A (en) * 2013-09-16 2014-01-01 中国农业科学院饲料研究所 Barley pest larva cosmetic matrix oil and preparing method thereof
CN104327934A (en) * 2014-06-05 2015-02-04 中北大学 Extraction and refining method of grease from barley pest
CN108472240A (en) * 2015-11-16 2018-08-31 C·桑端 The skin-protection product of the extract containing black soldier flies
CN105456155A (en) * 2015-11-23 2016-04-06 太仓安佑生物科技有限公司 Method for preparing cosmetic raw materials from Hermetia illucens larvas and application of method
KR20190011054A (en) * 2017-07-24 2019-02-01 계명대학교 산학협력단 Skin external application composition for promoting wound healing or cosmetic composition for improving wrinkle comprising oil of Tenebrio molitor mealworm
CN108283670A (en) * 2018-04-13 2018-07-17 张爱丽 A kind of pharmaceutical composition and preparation method thereof for treating burn and scald
CN110938485A (en) * 2018-09-22 2020-03-31 湖北远志黄粉虫养殖有限责任公司 Production method of yellow mealworm oil
CN111165656A (en) * 2020-01-09 2020-05-19 南京大学（溧水）生态环境研究院 Efficient preparation method of hermetia illucens freeze-dried powder

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黄友良等: "黑水虻资源化利用研究", 《中国资源综合利用》 *
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