CN1126598A

CN1126598A - External application plaster for hepatitis, hepatocirrhosis and hepatonecrosis

Info

Publication number: CN1126598A
Application number: CN94116525A
Authority: CN
Inventors: 肖利平
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-09-30
Filing date: 1994-09-30
Publication date: 1996-07-17
Anticipated expiration: 2014-09-30
Also published as: CN1054049C

Abstract

The external-use plaster is decocted peach leaf ointment with certain amount of peach kernel, centipede and pangolin scale powder on it. When used, the plaster is stuck onto the right liver area once each week and twice each treatment course. Clinical application shows its excellent curative effect on hepatitis, hepatocirrhosis and liver necrosis.

Description

The Dressed plaster of anti-hepatitis, liver cirrhosis, hepatic necrosis

The present invention relates to a kind of Chinese herbal medicine Dressed plaster, relate in particular to a kind of anti-hepatitis, the application compress of liver cirrhosis, hepatic necrosis.

Hepatitis, liver cirrhosis, hepatic necrosis are the healthy diseases of a kind of serious trouble victimization class, hepatitis can be divided into first type, B-mode, fourth type and non-a, non-b type, but no matter that is a kind of infected, its liver will change towards fibrosis (liver cirrhosis) direction, the lighter's pain in the hepatic region of liver cirrhosis, unable even wound is lost the labour force, and weight person then can be dead in a short time.This shows how to make a kind of medicine, can treat hepatitis, liver cirrhosis, hepatic necrosis effectively or be a major issue of health organization in the world today.

The objective of the invention is to adopt Liver Channel class Chinese herbal medicine formula and make plaster, and spreading on the hepatic region in addition, and reach the purpose of treatment.

The object of the present invention is achieved like this, Folium Persicae, Semen Persicae, Scolopendra, Squama Manis four flavors that will belong to the Liver Channel class have the Chinese medicine of blood circulation promoting and blood stasis dispelling, eliminating stagnation, removing obstruction in the collateral to relieve pain effect to be got all the ready by prescription, then Folium Persicae is decocted into cream and spreads out the powder mix homogeneously of the Semen Persicae that will grind again, Scolopendra, Squama Manis and spread and spread out on Folium Persicae cream on the cloth lining.

The performance of its four Chinese medicine is in the Dressed plaster of above-mentioned making:

1, Semen Persicae is the dry mature seed of rosaceous plant peach or mountain peach, bitter in the mouth, flat, and GUIXIN, liver, lung large intestine channel, its blood circulation promoting and blood stasis dispelling power is stronger, is the staple of clinical treatment stasis of blood resistance disease.

2, Scolopendra is the dry body of Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH, has another name called Gekko Swinhonis.Nature and flavor: suffering, temperature; Poisonous.The property of medicine: go into liver, the heart.Have stronger dispersing pathogen accumulation effect, be the medicine commonly used of surgery of Chinese medicine.

3, Squama Manis is the scute of Manidae animal Manitis, the original name Manitis.Nature and flavor: salty, be slightly cold.Its promoting blood circulation to remove blood stasis power is stronger, can the tonneau meridians and through sick institute, and being that Chinese traditional treatment blood clotting blood is poly-is sick medicine commonly used.

4, Folium Persicae is the leaf of above-mentioned plant peach or mountain peach, and its effect is identical with Semen Persicae.

Because hepatitis, liver cirrhosis, hepatic necrosis all belong to because of the liver cell function sustains damage, liver inner capillary tube, bile capillary inflammation are obstructed and cause hepatic necrosis, the disease that hepatic fibrosis changes, therefore adopt the Chinese medicine of blood circulation promoting and blood stasis dispelling, eliminating stagnation, collateral dredging tissue regeneration promoting to make its meridians, the dirty equal energy of device is unimpeded and make blood capillary liver in, bile capillary mediation recover normally to make the patient can obtain the good efficacy of pain relieving and treatment.By animal experiment, prove the effect that has anti-hepatic fibrosis preferably really and certain improve the liver function effect, in human body is on probation, obtained good effect too equally, specifically treat example and see example.

Below we will be further to Dressed plaster of the present invention, and preparation method thereof do further narration.

The Dressed plaster of a kind of anti-hepatitis, liver cirrhosis, hepatic necrosis, the soft extracts that it is characterized in that plaster is the Folium Persicae soft extracts, the medicated powder that is spread on it is for less than 100 purpose fine-grained powders, and this powder mixes by peach kernel powder, Scolopendra powder, Squama Manis powder, and this three's consumption proportion closes and is

Semen Persicae 29.4～37% Scolopendras 23.5～29.7%

Squama Manis 33.3～47.1%

And the consumption proportion of Folium Persicae and medicated powder pass is: Folium Persicae 78.2%～96%, medicated powder 4～2.1%.

The manufacturing process of this kind Dressed plaster is:

1, soft extracts

It is standby that Folium Persicae is boiled into paste;

2, make medicated powder

Semen Persicae, Scolopendra, Squama Manis are broken into powder by proportional quantity, and sieve, mix then and mix thoroughly with 100 mesh sieves;

3, applying cream makes

With Folium Persicae cream spread out in cloth lining go up, the stand is even, the medicated powder with quantitative proportioning evenly is spread on the cream then, treats that little drying in the air add a cover the low encapsulation of stannum.

With the plaster that above-mentioned prescription and method for making make, the time spent is opened tinfoil, is affixed on right side of body hepatic region, and a week is used in every subsides, and two subsides are a course of treatment, use two courses of treatment at most, and special circumstances can just can be received better curative effect with two two courses of treatment.

In treatment in the past, no matter be chronic active hepatitis, or hepatitis gravis (hepatic necrosis), liver cirrhosis, in treatment, take the way safeguarded greatly, promptly keep the certain nutrition of patient and give medicine, the injection of various vitaminss, and do not have what specific aim, promptly these medicines itself can not make hepatocyte recover, regeneration can not produce function of detoxification.Even, when cerebral edema, emergency case such as hemorrhage, also can only take some emergency measures to make its respite, but can not hepatocyte is restored so produce hepatic coma as patient.Its last liver still develops until death towards continuing downright bad direction.

And deposited patch of the present invention is behind the hepatic region, and it can make the cell of hepatic necrosis recover or to regenerate, and makes hepatic fibrosis obtain stoping, and improved the detoxification ability of liver, thereby make liver reach recovery.All these effects not only are confirmed in animal experiment (seeing Appendix 1), and exist the human clinical to be verified on probation.Below we will enumerate the illustration of its three kinds of Recipe of plaster products and the clinical result of use of the present invention.

Embodiment 1 Dressed plaster 1 of the present invention

Fry in shallow oil into cream with Folium Persicae and make to apply cream, do dusting by the medicated powder of Semen Persicae, Scolopendra, Squama Manis three flavor medicines, this three's amount ratio is: Semen Persicae 29.4% Scolopendra 23.5%, and Squama Manis 47.1%, the proportioning of medicated powder total amount and Folium Persicae is: medicated powder 14.5% Folium Persicae 85.5%

Embodiment 2 Dressed plasters 2 of the present invention

Fry in shallow oil into cream with Folium Persicae equally, do dusting by the medicated powder of Semen Persicae, Scolopendra, Squama Manis three flavor medicines, this three's amount ratio is: Semen Persicae 37%, and Scolopendra 29.7%, Squama Manis 33.3%, Folium Persicae is medicated powder 9.7% Folium Persicae 90.3% with medicated powder total amount ratio

Embodiment 3 Dressed plasters 3 of the present invention

Fry in shallow oil into cream with Folium Persicae and make to apply cream, do dusting by the medicated powder of Semen Persicae, Scolopendra, Squama Manis three flavor medicines, this three's amount ratio is: Semen Persicae 32%, and Scolopendra 29%, Squama Manis 39%, medicine branch total amount is medicated powder 9.4% Folium Persicae 90.6% with the ratio of Folium Persicae

Adopt the example of clinical cure hepatopathy of the present invention

Example 1 health * * male 48 years old, suffered from hepatitis B 2 years, outbreak repeatedly, the every index of serum liver function descends, the hepatic fibrosis index liter, SGPT2000/ml, BSP test obvious retention, patient's malaise, inappetence is felt sick, is vomitted, and epigastrium is swollen, and often medication is invalid.

After adopting two weeks of plaster external application of the present invention, every index is normal, and malaise disappears, and appetite is better, does not have the vomiting sense of feeling sick, and abdominal distention disappears and leaves hospital, after observe the several months again, still do not have repeatedly.

Example 2 Gus * * male 32 years old, suffer from hepatitis A 1 year, and suffered from hepatitis B 2 months, the subcutaneous hemorrhage point, serious jaundice 14 days, spirit is poor, drowsiness, and the fidgets on occasion uneasiness of making an uproar is arranged, liver function: SPGPT 1000/ML, usually in 170umol/L SBP test retention, prolonged prothrombin is diagnosed as hepatitis gravis to serum bilirubin.

Take a turn for the better rapidly with the back state of an illness around the plaster of the present invention, jaundice disappears, and spirit is normal, and is subcutaneous not hemorrhage again, liver function SGPT400/ml, and serum gallbladder essence 120umol/L SBP test is normal, and prothrombin time is left hospital after normal two months, not recurrence again.

Example 3 Zhao * * man suffered from surplus the chronic active hepatitis 10 year in 58 years old, and hepatic ascites is half a year, spits blood twice greatly, is diagnosed as the hepatitis end-age cirrhosis.The patient becomes thin, and spiritual extreme difference is unable to leave the bed, sallow complexion, and liver function descends.

With two courses of treatment of plaster treatment of the present invention, the state of an illness takes a turn for the better gradually, and ascites disappears, and haematemesis stops, can out-of-bed activity after 1 year, and liver function recovery is normal, can not recur liver ascites again as normal person's activity freely after 2 years.

By above-mentioned clinical example as seen, plaster of the present invention has significant curative effect to hepatitis, liver cirrhosis, hepatic necrosis serious symptom hepatopathy, this shows that the present invention has good social valency and plants, and treatment is simple, makes easily, therefore has excellent economic value again.

Claims

1, the Dressed plaster of a kind of anti-hepatitis, liver cirrhosis, hepatic necrosis, the soft extracts that it is characterized in that plaster is the Folium Persicae soft extracts, the medicated powder that is spread on it is less than 100 purpose fine-grained powders, and this powder is mixed by peach kernel powder, Scolopendra powder, Squama Manis powder, and it is Semen Persicae 29.4～37% Scolopendras 23.5～29.7% Squama Maniss 33.3～47.1% that this three's consumption proportion closes

2, press the Dressed plaster of the described anti-hepatitis of claim 1, liver cirrhosis, hepatic necrosis, the ratio that it is characterized in that medicated powder total amount and Folium Persicae is: medicated powder 14.5%, and Folium Persicae 85.5%, this medicated powder composition and proportioning are: Semen Persicae 29.4%, Scolopendra 23.5%, Squama Manis 47.1%.

3, by the Dressed plaster of the described anti-hepatitis of claim 1, liver cirrhosis, hepatic necrosis, it is characterized in that medicated powder total amount and Folium Persicae ratio are 9.7% and 90.3%, the proportioning of Semen Persicae, Scolopendra, Squama Manis is 37%, 29.7%, 33.3% in the medicated powder.

4, by the Dressed plaster of the described anti-hepatitis of claim 1, liver cirrhosis, hepatic necrosis, it is characterized in that medicated powder total amount and Folium Persicae ratio are 9.4% and 90.6%, the proportioning of Semen Persicae, Scolopendra, Squama Manis is 32%, 29%, 39% in the medicated powder.