CN1212149C - Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof - Google Patents
Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof Download PDFInfo
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- CN1212149C CN1212149C CN 03156426 CN03156426A CN1212149C CN 1212149 C CN1212149 C CN 1212149C CN 03156426 CN03156426 CN 03156426 CN 03156426 A CN03156426 A CN 03156426A CN 1212149 C CN1212149 C CN 1212149C
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Abstract
The present invention relates to a traditional Chinese medicine preparation for treating attention deficient disorder (ADD) and a preparation method thereof. The preparation uses tortoise shell, dragon bone, tuckahoe, drug sweetflag rhizome, pummelo peel, prepared rehmannia root, polygala root, dogwood fruit, Chinese yam, corktree bark and stiff silkworm as raw materials. The present invention can effectively treat and radically cure ADD, the life quality of ill children is improved greatly, and the present invention has higher cure and rehabilitation effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of childhood hyperkinetic syndrome and preparation method thereof.
Background technology
Childhood hyperkinetic syndrome is a kind of common behavior disorder of children disease, claims Cerebral function slight maladjustment or slight cerebral function disorder syndrome or attention deficit hyperactivity disorder again.It is many that this sick school age population is sent out the patient, boy is more than girl, and the infant that has has conduct disorder, and it is absent minded poor with emotional stability still to exist after infant over half approximately adolesces, can not be engaged in the normal Bank of Communications of interpersonal relation, aggressivity and destructive strong life obstacle.Current, treatment childhood hyperkinetic syndrome Western medicine commonly used for example adopt these Western medicine such as methylphenidate, amfetamine not only to cost an arm and a leg, and toxic and side effects is also higher, is unfavorable for childhood development, and cure rate is also low.Utilization Chinese herbal treatment childhood hyperkinetic syndrome is the work of always studying, but present medicine can only alleviate the state of an illness, can not effect a radical cure, and curative effect can not be satisfactory.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of childhood hyperkinetic syndrome and preparation method thereof, can treat and effect a radical cure childhood hyperkinetic syndrome, and the body constitution and the intelligence of infant is had the raising effect, and have no side effect.And this preparation method is simple and easy to do, extracts active ingredient height in the medicinal herbs, and cost of manufacture is low.
Solution of the present invention is according to the rule of the traditional Chinese medical science to childhood hyperkinetic syndrome treatment, i.e. the body resistance strengthening and constitution consolidating, the kidney invigorating collateral dredging.Chinese medicine thinks that development in children is rapid, is prone to yin and yang imbalance, caused by liver and kidney deficiency, hyperactivity of YANG due to deficiency of YIN is disturbed and various symptoms can be occurred during the mind, and hepatic and renal YIN deficiency be primary disease this, hyperactivity of YANG due to deficiency of YIN, irritability are the mark of primary disease.The present invention forms according to above-mentioned rule, can the kidney invigorating collateral dredging, and again can the body resistance strengthening and constitution consolidating.Radix Rehmanniae Preparata of the present invention, Carapax Et Plastrum Testudinis, Fructus Corni enriching yin and nourishing kidney, enriching kidney essence, nourishing the blood and yin is to mend congenital defect; Carapax Et Plastrum Testudinis is sweet to be slightly cold, nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone, the reinforcing the heart of nourishing blood; Liver and kidney is thanks to then gone into Fructus Corni again, to strengthen the power of nourishing the liver and kidney replenishing essence; The Radix Polygalae mind tranquilizing and the heart calming, strongly fragrant eliminating phlegm looses; The Rhizoma Acori Graminei intelligence promoting and the mind tranquilizing, a surname's air to open key, wind-damp dispelling dampness is stimulated the menstrual flow; The Os Draconis tranquillizing the mind by relieving convulsion, with Radix Polygalae and Rhizoma Acori Graminei mutually 5, more apparent eliminating the phlegm had one's ideas straightened out, the merit of mind tranquilizing and the heart calming.The Rhizoma Dioscoreae antidiarrheal of astringing the lung, lung benefiting spleen invigorating, the arresting sweating that promotes the production of body fluid, reinforcing the kindey to control nocturnal emission.The present invention has eliminating evil just the wound, and set upright and do not stay heresy, the kidney invigorating collateral dredging, warm network blood stasis dispelling, intelligence promoting and the mind tranquilizing, a surname's air to open key, the strongly fragrant eliminating phlegm that looses, wind-damp dispelling dampness is stimulated the menstrual flow, and has the sick effect of good radical cure.
The present invention is the medicament of being made by the following weight proportion raw material
90～250 parts of 200～400 parts of Fructus Corni of 200～400 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
70～190 parts of 20～60 parts of Bombyx Batryticatus of 20～60 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
200～400 parts of 70～190 parts of Os Draconis of 70～190 parts of Poria of Cortex Phellodendri
90～250 parts of 100～300 portions of Rhizoma Dioscoreaes of Radix Polygalae
The weight proportion of each raw material of formula optimization of the present invention is
120～180 parts of 250～350 parts of Fructus Corni of 250～350 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
100～140 parts of 30～55 parts of Bombyx Batryticatus of 30～55 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
250～350 parts of 100～140 parts of Os Draconis of 100～140 parts of Poria of Cortex Phellodendri
120～180 parts of 150～250 portions of Rhizoma Dioscoreaes of Radix Polygalae
The weight proportion of best each raw material of prescription of the present invention is
150 parts of 300 parts of Fructus Corni of 300 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
120 parts of 50 parts of Bombyx Batryticatus of 50 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
300 parts of 120 parts of Os Draconis of 120 parts of Poria of Cortex Phellodendri
150 parts of 200 portions of Rhizoma Dioscoreaes of Radix Polygalae
Described Chinese medicine preparation is a said capsule on any pharmaceutics.
The method for preparing preparation of the present invention is: get Rhizoma Acori Graminei, Exocarpium Citri Grandis is ground into fine powder, with Carapax Et Plastrum Testudinis, Os Draconis, Poria and Bombyx Batryticatus decoct with water three times, 5～7 times of amounts that at every turn add above-mentioned medicine volume decocted collecting decoction 2～3 hours, filter, filtrate for later use is again with Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, add 2～3 times of amounts of above-mentioned medicine volume at every turn, extracted 1～2 hour, merge extractive liquid, filters, and filtrate recycling ethanol is to there not being the alcohol flavor, above-mentioned two kinds of filtrates are mixed, being concentrated in 80 temperature relative densities is 1.39 clear paste, and drying is pulverized and added the starch that accounts for medicated powder total amount 5～15%, be mixed, incapsulate.
Preparation capsule of the present invention is called " many moving peaceful " capsules, and is oral usually, one time 3～5, three times on the one, adorn 0.38 gram for every.
Clinical drug of the present invention uses the result to show that following advantage is arranged;
1, the Chinese herbal medicine each component selected for use of the present invention meets the pharmaceutical control law regulation, utilizes the comprehensive function treatment childhood hyperkinetic syndrome of the Chinese medicine of respectively distinguishing the flavor of, and does not have chemical sweeting agent, and is nontoxic to human body.Acute and be that 90 days toxicity tests of successive administration show that underproof animal end sees any toxic reaction for a long time through animal, its main organs does not have tangible change yet, mice is 300g crude drug/kg to the maximum tolerated dose of medicine of the present invention, is 300 times of clinical people's consumption, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, and rich in proteins in the medicine, glucose, phlegmatic temperament, organic acid, fatty oil, vitamin and nearly tens seed amino acids also contain various trace elements such as ginsenoside and ferrum, are beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention can treat and effect a radical cure childhood hyperkinetic syndrome effectively, and other similar disease is also had better curative effect, has improved the life quality of infant greatly, and higher healing rehabilitation efficacy is arranged.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to childhood hyperkinetic syndrome; Treatment childhood hyperkinetic syndrome patient 300 examples, radical cure rehabilitation 84 examples, produce effects 204 examples, invalid 12 examples, effective percentage reaches more than 96%.
The specific embodiment
Take by weighing raw material by following proportioning;
Carapax Et Plastrum Testudinis 300g Radix Rehmanniae Preparata 300g Fructus Corni 150g
Rhizoma Acori Graminei 50g Exocarpium Citri Grandis 50g Bombyx Batryticatus 120g
Cortex Phellodendri 120g Poria 120g Os Draconis 300g
Radix Polygalae 200g Rhizoma Dioscoreae 150g
Production method is as follows;
Get Rhizoma Acori Graminei, Exocarpium Citri Grandis is ground into fine powder, and Carapax Et Plastrum Testudinis, Os Draconis, Poria and Bombyx Batryticatus are decocted with water three times, adds 5 times of amounts of above-mentioned medicine volume at every turn, decocts 2 hours, collecting decoction filters, filtrate for later use.Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri are added 60% alcohol reflux three times again, add 3 times of amounts of above-mentioned medicine volume at every turn, extracted 1 hour, merge extractive liquid, filters, and filtrate recycling ethanol is to there not being the alcohol flavor.Above-mentioned two kinds of filtrates are mixed, and being concentrated in 80 temperature relative densities is 1.39 clear paste, and drying is pulverized and added the starch that accounts for medicated powder total amount 8%, is mixed, and incapsulates.Adorn 0.38 gram, make about 1000 for every.
Preparation capsule of the present invention is called " many moving peaceful " capsules, and is oral usually, one time 3～5, three times on the one.
Claims (5)
1, a kind of Chinese medicine preparation for the treatment of childhood hyperkinetic syndrome is characterized in that it is the medicament of being made by the following weight proportion raw material
90～250 parts of 200～400 parts of Fructus Corni of 200～400 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
70～190 parts of 20～60 parts of Bombyx Batryticatus of 20～60 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
200～400 parts of 70～190 parts of Os Draconis of 70～190 parts of Poria of Cortex Phellodendri
90～250 parts of 100～300 portions of Rhizoma Dioscoreaes of Radix Polygalae
2, the Chinese medicine preparation of treatment childhood hyperkinetic syndrome according to claim 1, wherein the weight proportion of each raw material is
120～180 parts of 250～350 parts of Fructus Corni of 250～350 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
100～140 parts of 30～55 parts of Bombyx Batryticatus of 30～55 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
250～350 parts of 100～140 parts of Os Draconis of 100～140 parts of Poria of Cortex Phellodendri
120～180 parts of 150～250 portions of Rhizoma Dioscoreaes of Radix Polygalae
3, the Chinese medicine preparation of treatment childhood hyperkinetic syndrome according to claim 1, wherein the weight proportion of each raw material is
150 parts of 300 parts of Fructus Corni of 300 parts of Radix Rehmanniae Preparata of Carapax Et Plastrum Testudinis
120 parts of 50 parts of Bombyx Batryticatus of 50 parts of Exocarpium Citri Grandises of Rhizoma Acori Graminei
300 parts of 120 parts of Os Draconis of 120 parts of Poria of Cortex Phellodendri
150 parts of 200 portions of Rhizoma Dioscoreaes of Radix Polygalae
4, according to the Chinese medicine preparation of claim 1,2 or 3 described treatment childhood hyperkinetic syndromes, it is characterized in that: described Chinese medicine preparation is a said capsule on any pharmaceutics.
5, a kind of method for preparing the described Chinese medicine preparation of claim 1, it is characterized in that: get Rhizoma Acori Graminei, Exocarpium Citri Grandis is ground into fine powder, with Carapax Et Plastrum Testudinis, Os Draconis, Poria and Bombyx Batryticatus decoct with water three times, 5～7 times of amounts that at every turn add above-mentioned medicine volume, decocted 2～3 hours, collecting decoction filters filtrate for later use, again with Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, 2～3 times of amounts that at every turn add above-mentioned medicine volume were extracted merge extractive liquid, 1～2 hour, filter, filtrate recycling ethanol is not to there being the alcohol flavor, will above-mentioned two kinds of filtrates mixing, and being concentrated in 80 temperature relative densities is 1.39 clear paste, drying, pulverize the starch that adding accounts for medicated powder total amount 5～15%, be mixed, incapsulate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03156426 CN1212149C (en) | 2003-08-27 | 2003-08-27 | Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03156426 CN1212149C (en) | 2003-08-27 | 2003-08-27 | Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1485088A CN1485088A (en) | 2004-03-31 |
| CN1212149C true CN1212149C (en) | 2005-07-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 03156426 Expired - Lifetime CN1212149C (en) | 2003-08-27 | 2003-08-27 | Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344312C (en) * | 2004-11-10 | 2007-10-24 | 赵振伟 | Prepn process of granule for treating children's hyperkinesia and its quality control method |
| CN104224975A (en) * | 2014-08-23 | 2014-12-24 | 布焕景 | Traditional Chinese medicinal composition for treating phlegm stagnation type attention deficit hyperactivity disorder and application thereof |
| CN104524464A (en) * | 2014-12-30 | 2015-04-22 | 陈淑娟 | Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation |
| CN105816634A (en) * | 2016-05-11 | 2016-08-03 | 王兆阳 | Adjuvant medicine for rehabilitation treatment of hyperactivity in department of pediatrics |
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2003
- 2003-08-27 CN CN 03156426 patent/CN1212149C/en not_active Expired - Lifetime
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Granted publication date: 20050727 |