CN112629187A - GMP high temperature sterilization heated air circulation oven convenient to temperature monitoring - Google Patents
GMP high temperature sterilization heated air circulation oven convenient to temperature monitoring Download PDFInfo
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- CN112629187A CN112629187A CN202110100936.1A CN202110100936A CN112629187A CN 112629187 A CN112629187 A CN 112629187A CN 202110100936 A CN202110100936 A CN 202110100936A CN 112629187 A CN112629187 A CN 112629187A
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B9/00—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards
- F26B9/06—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards in stationary drums or chambers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/001—Drying-air generating units, e.g. movable, independent of drying enclosure
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/004—Nozzle assemblies; Air knives; Air distributors; Blow boxes
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/02—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
- F26B21/04—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
- F26B21/06—Controlling, e.g. regulating, parameters of gas supply
- F26B21/08—Humidity
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B23/00—Heating arrangements
- F26B23/04—Heating arrangements using electric heating
- F26B23/06—Heating arrangements using electric heating resistance heating
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/044—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum for drying materials in a batch operation in an enclosure having a plurality of shelves which may be heated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
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- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Drying Of Solid Materials (AREA)
Abstract
The invention discloses a GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring, which comprises an electric control cabinet controlled by the whole machine; the main drying oven is used for sterilizing and drying medicines, and the conditional drying oven is used for drying operation instruments, and the main drying oven and the conditional drying oven are closely mounted or integrally packaged through a shell; the conditional oven comprises a small box body, and an air inlet disinfection pipeline is arranged at the top of the small box body; a water storage box and a disinfectant liquid storage box are arranged at the bottom of the small box body; the main oven comprises an outer box body with a hollow front end and an inner box body fixed on the inner side of the outer box body through support legs; the inner edge of the outer box body and the outer edge of the inner box body are sealed and welded through an annular sealing plate to form an annular channel; the GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring adopts the large and small oven bodies which are integrally packaged or closely mounted, the small oven body is used as an environment regulating and controlling box and a sterilization and drying box for instruments, and the large oven body is used as a main oven body, so that the drying is more energy-saving, and the sterilization effect is better.
Description
Technical Field
The invention relates to an oven, in particular to a GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring, and belongs to the technical field of ovens.
Background
GMP is a set of mandatory standards applicable to pharmaceutical, food and other industries, and requires enterprises to meet the requirements of sanitary quality according to relevant national regulations from the aspects of raw materials, personnel, facilities and equipment, production process, packaging and transportation, quality control and the like, so that an operable operation specification is formed to help the enterprises to improve the sanitary environment of the enterprises, discover problems existing in the production process in time and improve the problems; briefly, GMP requires that manufacturing enterprises such as pharmacy, food, etc. should possess good production facilities, reasonable production process, perfect quality control and strict detecting system, ensure that final product quality (including food safety and sanitation, etc.) accords with the legislation requirement, wherein, to the pharmaceutical industry, because the pharmaceutical workshop needs to go on under aseptic environment, some instruments that have used in the external world need to be disinfected, simultaneously some pharmacy raw and other materials are because contain more moisture and bacterium, before getting into the production process, also need disinfect and dry, avoid bringing into the workshop with bacterium, cause the pollution transmission, for this reason, chinese patent application no: 201210165319.0, discloses a GMP high temperature sterilization heated air circulation oven convenient to temperature monitoring, it utilizes the circulation of inside hot-blast, effectively kills the bacterium on apparatus and the raw materials, can monitor the humidity in the oven constantly, avoids destroying the quality of raw materials, but its sterilization quality is poor, and can't satisfy the requirement of drying process to drying equipment.
Disclosure of Invention
In order to solve the problems, the invention provides a GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring, which adopts a large box body and a small box body which are integrally packaged or closely mounted, wherein the small box body is used as an environment regulating and controlling box and a sterilization drying box for instruments, and the large box body is used as a main oven, so that the drying is more energy-saving, and the sterilization effect is better; the small box body and the small box body are arranged, so that the small box body can be heated more energy-saving, when the small box body is used as an environment adjusting and controlling box due to the fact that high-temperature environment is required for sterilization of instruments, the high-temperature environment for sterilization of the instruments is subjected to humidity adjustment and then is driven into the large box body, the large capacity of the large box body is utilized to diffuse heating temperature, one temperature grade is reduced, excessive drying temperature of medicine raw materials is avoided, meanwhile, the large box body and the small box body can form a sealed circulating environment, and after the small box body is subjected to pressure reduction, the large box body can be synchronously subjected to pressure; after decompression, the large box body can be independently heated or the small box body can be heated and circulated, and during environment regulation and control, the small box body can control the temperature, humidity, sterilization and pressure of circulating gas of the large box body according to the requirements of medical products.
The GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring comprises an electric control cabinet controlled by a whole machine; the main drying oven is used for sterilizing and drying medicines, and the conditional drying oven is used for drying operation instruments, and the main drying oven and the conditional drying oven are closely mounted or integrally packaged through a shell;
the conditional oven comprises a small box body, and an air inlet disinfection pipeline is arranged at the top of the small box body; a water storage box and a disinfectant liquid storage box are arranged at the bottom of the small box body; the bottom of the water storage box and the bottom of the disinfectant liquid storage box are respectively provided with an ultrasonic vibrator; the inner sides of the water storage box and the disinfectant liquid storage box are respectively provided with a high-low water level probe; the end parts of the water storage box and the disinfectant liquid storage box are respectively connected to a water replenishing pipeline through a one-way valve and an electromagnetic valve; a sealing plate is fixed above the water storage box and the disinfectant liquid storage box of the small box body; the middle part of the sealing plate is provided with an air outlet; an air exhaust fan is fixed on the bottom surface of the sealing plate at the air outlet; a liquid collecting box is fixed on the top surface of the sealing plate; a liquid discharge valve is arranged at the end part of the liquid collection box; the middle part and two sides of the liquid collecting box are respectively integrally manufactured into a convex pipe with two hollow ends, and the top of the convex pipe is higher than the top surface of the liquid collecting box; the convex pipes on two sides are provided with waterproof caps; the top of the middle convex pipe is provided with a tee joint; the middle end of the tee joint is connected to an air inlet valve outside the small box body; the liquid collecting box is provided with a stress seat outside the convex pipe and the tee joint; a regulating and controlling pipe is fixed on the stress seat; the bottom of the regulating and controlling pipe is hermetically communicated with the upper end of the tee joint through an air hood; a step-shaped object placing table is arranged outside the regulating and controlling pipe; the article placing table is of a net structure; the top of the regulating and controlling pipe is closed, and a plurality of internal circulation pipelines and external circulation pipelines are embedded in the regulating and controlling pipe; the inner wall of the small box body is provided with an air injection ring in an annular or array shape opposite to the object placing table; the inner circulation pipeline is connected to the air inlet end of the air injection ring through an inner circulation fan; the external circulation pipeline is connected to an air outlet valve outside the small box body; a heating pipe array is arranged between the regulating and controlling pipe and the object placing table; the regulating and controlling pipe is provided with thermal circulation through holes at intervals; a temperature and humidity transmitter is arranged at the top of the regulating and controlling pipe;
the main oven comprises an outer box body with a hollow front end and an inner box body fixed on the inner side of the outer box body through support legs; the inner edge of the outer box body and the outer edge of the inner box body are sealed and welded through an annular sealing plate to form an annular channel; a door body is arranged on the front side of the inner box body; two rows of grid plates are fixed at two sides in the inner box body at intervals; the bottom of the grating plate and the inner side of the inner box body are provided with closed covers; an air inlet is arranged between the end part of the closed cover and the annular channel; the middle part of the bottom surface of the outer box body is communicated with an air inlet fan; the air inlet fan is connected to the air outlet valve through a pipeline; the inner box body is connected to the air inlet valve through an open valve and an air exhaust fan; the bottom of the inner box body is provided with an electric heating tube; a temperature and humidity transmitter is fixed at the upper part of the inner side of the inner box body; and an independent circulating pipeline is arranged between the bottom surface of the outer box body and the top surface of the inner box body through a circulating fan and a switch valve.
Furthermore, a hydraulic gate valve is arranged on the lower portion of the sealing plate of the small box body; the top of the small box body is connected to a vacuum-pumping pipeline through a one-way valve and a switch valve.
Furthermore, a frame body is welded to the outer portion of the annular sealing plate, and an outer sealing door is arranged on the frame body.
Further, the operation process of the oven is as follows:
the condition drying oven completes sterilization and drying of instruments through internal circulation, the external circulation provides drying and sterilizing conditions for the main drying oven, and meanwhile, the condition drying oven provides pressure reduction conditions for the main drying oven through a vacuum pumping pipeline; the main oven finishes the drying of the medical products in the temperature control, humidity control, sterilization and pressure control environments.
Further, the working process of the conditional oven is as follows:
firstly, feeding, namely respectively feeding the instrument and/or medicine raw materials into an object placing table and a grid plate; the instrument cleaning liquid is dripped into the liquid collecting box for collection and is periodically discharged outside through the liquid discharging valve; the convex pipe on the liquid collecting box prevents liquid from entering the water storage box and/or the disinfectant liquid storage box through the waterproof cap;
secondly, selecting or inputting condition control, inputting control data into the electric control cabinet through the integrated machine, simultaneously detecting and acquiring temperature and humidity data by using a temperature and humidity transmitter, sending the temperature and humidity data to the electric control cabinet, carrying out temperature and humidity control after threshold judgment is carried out through the electric control cabinet, and simultaneously selecting gas sterilization or liquid sterilization and a sterilization period by the electric control cabinet according to the type of an instrument or a product;
then, the ultrasonic vibrators at the bottom of the water storage box and/or the disinfectant liquid storage box are driven to carry out humidification and liquid sterilization according to the conditions selected in the previous step and the humidity data acquired by the temperature and humidity transmitter; the fog generated by the vibration of the ultrasonic vibrator is lifted up by the air exhaust fan and enters the regulating and controlling pipe through the convex pipe; when gas sterilization is carried out, sterilizing gas is injected into the gas inlet sterilizing pipeline and downwards splashed to the object placing table through the top of the small box body; meanwhile, a heating pipe array outside the regulating and controlling pipe performs PID operation according to preset temperature and real-time collected temperature so as to complete temperature response, when internal circulation is performed, an internal circulation fan pumps sterilizing gas outside the regulating and controlling pipe, heat generated by the heating pipe array and humidifying mist and sterilizing mist inside the regulating and controlling pipe to mix, the mixed gas is sent to an air inlet of an air injection ring through an internal circulation pipeline, high-heat mixed gas is injected to the top surface of the object placing table through a nozzle array on the air injection ring, the bottom surface of the object placing table is directly heated and dried through the heating pipe array, and the heated gas enters the regulating and controlling pipe again through the heating pipe array to form internal circulation; when external circulation is carried out, external gas is pumped into the regulating and controlling pipe through the air inlet valve and the tee joint, and is sent into the main oven through the external circulation pipeline and the air outlet valve after regulation and control are finished; the gas sent into the main oven is regulated and controlled by temperature, humidity and sterilization.
And further, when the instrument or medicine raw materials need pressure regulation, sterilization and drying, the hydraulic gate valve is directly closed, the small box body or the inner box body is vacuumized through the vacuum pumping pipeline, and at the moment, the small box body or the inner box body is subjected to combined temperature control or independent temperature control.
Further, the working process of the main oven is as follows:
the main oven receives the gas sent by the condition oven, and the gas finishes temperature regulation, humidity regulation and sterilization regulation; the gas enters the annular channel and is pumped by the air exhaust fan at the top of the inner box body, so that the gas is pumped into the closed cover through the air inlet, the regulating gas is uniformly provided for the medicine raw material on the top surface of the closed cover through the grid plate at the top of the closed cover, finally, the gas returns to the conditional oven again through the open valve, the air exhaust fan and the air inlet valve, and enters the annular channel again after the environment regulation is carried out again, and a closed loop is formed; when the temperature condition collected by the temperature and humidity transmitter does not reach the drying temperature of the product, the opening degree of the opening valve is reduced until the opening degree is closed, and meanwhile, the electric heating pipe is used for heat supplement; and the circulating fan is utilized to carry out internal temperature control circulation.
Compared with the prior art, the GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring adopts the large and small oven bodies which are integrally packaged or closely mounted, the small oven body is used as the environment regulating and controlling box and the sterilization and drying box of instruments, and the large oven body is used as the main oven body, so that the drying is more energy-saving, and the sterilization effect is better.
Drawings
FIG. 1 is a schematic view of the close-fitting installation structure of the main oven and the conditional oven of the present invention.
Fig. 2 is a schematic view of the structure of the main oven and the conditional oven integrally packaged by the housing.
Fig. 3 is a schematic structural diagram of an embodiment of the conditional oven of the present invention.
Fig. 4 is a schematic structural diagram of another embodiment of the conditional oven of the present invention.
Fig. 5 is a schematic structural diagram of the main oven of the present invention.
Fig. 6 is a schematic structural diagram of the inner side of the main oven in a top view.
Detailed Description
Example 1:
the GMP high-temperature sterilization hot air circulation oven convenient for temperature monitoring as shown in fig. 1 and 2 comprises an electric control cabinet a controlled by a whole machine; the main oven B is used for sterilizing and drying medicines, and the conditional oven C is used for drying operation instruments, and the main oven B and the conditional oven C are closely mounted or integrally packaged through a shell;
as shown in fig. 3, the conditional oven C comprises a small box 1, and an air inlet disinfection pipeline 25 is arranged at the top of the small box 1; the bottom of the small box body 1 is provided with a water storage box 2 and a disinfectant liquid storage box 3; the bottom of the water storage box 2 and the bottom of the disinfectant liquid storage box 3 are respectively provided with an ultrasonic vibrator 4; the inner sides of the water storage box 2 and the disinfectant liquid storage box 3 are respectively provided with a high-low water level probe 5; the end parts of the water storage box 2 and the disinfectant liquid storage box 3 are respectively connected to a water replenishing pipeline 6 through a one-way valve and an electromagnetic valve; a sealing plate 7 is fixed above the water storage box and the disinfectant liquid storage box of the small box body 1; the middle part of the sealing plate 7 is provided with an air outlet; an air exhaust fan 8 is fixed on the bottom surface of the sealing plate 7 at the air outlet; a liquid collecting box 9 is fixed on the top surface of the sealing plate 7; a liquid discharge valve 10 is arranged at the end part of the liquid collecting box 9; the middle part and two sides of the liquid collecting box 9 are respectively and integrally manufactured into a convex tube 11 with two hollow ends, and the top of the convex tube 11 is higher than the top surface of the liquid collecting box 9; the convex pipes on two sides are provided with waterproof caps 12; the top of the middle convex pipe 11 is provided with a tee joint 13; the middle end of the tee joint 13 is connected to an air inlet valve 14 outside the small box body; the liquid collecting box 9 is provided with a stress seat 15 outside the convex pipe and the tee joint; a regulating and controlling pipe 16 is fixed on the stress seat 15; the bottom of the regulating and controlling pipe 16 is hermetically communicated with the upper end of the tee joint 13 through an air hood; a step-shaped object placing table 17 is arranged outside the regulating and controlling pipe 16; the object placing table 17 is of a net structure; the top of the regulating and controlling pipe 16 is closed, and a plurality of internal circulation pipelines 18 and external circulation pipelines 19 are embedded; the inner wall of the small box body 1 is provided with an air injection ring 20 opposite to the object placing table in an annular or array shape; the internal circulation pipeline 18 is connected to the air inlet end of the air injection ring 20 through an internal circulation fan 21; the external circulation pipeline 19 is connected to an air outlet valve 22 outside the small box body; a heating pipe array 23 is arranged between the regulating and controlling pipe 16 and the object placing table 17; the regulating and controlling pipe 16 is provided with thermal circulation through holes at intervals; a temperature and humidity transmitter 24 is arranged at the top of the regulating and controlling pipe 16;
as shown in fig. 5 and 6, the main oven B includes an outer box 27 with a hollow front end, and an inner box 28 fixed to the inner side of the outer box by means of support legs; an annular channel 30 is formed between the inner edge of the outer box body 27 and the outer edge of the inner box body 28 through sealing welding of an annular sealing plate 29; a door body is arranged on the front 28 side of the inner box body; two rows of grid plates 31 are fixed at two sides in the inner box body 28 at intervals; the bottom of the grating plate 31 and the inner side of the inner box body 28 are provided with closed covers 32; an air inlet 33 is arranged between the end part of the closed cover 32 and the annular channel 29; the middle part of the bottom surface of the outer box body 27 is communicated with an air inlet fan 34; the inlet fan 34 is connected to the outlet valve 22 through a pipe; the inner box 28 is connected to the intake valve 14 through an open valve 35 and an extraction fan 36; the bottom of the inner box body 27 is provided with an electric heating tube 37; a temperature and humidity transmitter 24 is fixed on the upper part of the inner side of the inner box body 27; an independent circulation pipeline 39 is arranged between the bottom surface of the outer box body 27 and the top surface of the inner box body 28 through a circulation fan 38 and a switch valve.
A frame body 40 is welded outside the annular sealing plate 29, and an external sealing door 41 is arranged on the frame body 40.
In yet another embodiment shown in fig. 4, the small box 1 is provided with a hydraulic gate valve 25 at the lower part of the sealing plate; the top of the small box body 1 is connected to a vacuum-pumping line 26 through a one-way valve and a switch valve.
The working process of the oven is as follows:
the condition drying oven completes sterilization and drying of instruments through internal circulation, the external circulation provides drying and sterilizing conditions for the main drying oven, and meanwhile, the condition drying oven provides pressure reduction conditions for the main drying oven through a vacuum pumping pipeline; the main oven finishes the drying of the medical products in the temperature control, humidity control, sterilization and pressure control environments.
The working process of the conditional oven is as follows:
firstly, feeding, namely respectively feeding the instrument and/or medicine raw materials into an object placing table and a grid plate; the instrument cleaning liquid is dripped into the liquid collecting box for collection and is periodically discharged outside through the liquid discharging valve; the convex pipe on the liquid collecting box prevents liquid from entering the water storage box and/or the disinfectant liquid storage box through the waterproof cap;
secondly, selecting or inputting condition control, inputting control data into the electric control cabinet through the integrated machine, simultaneously detecting and acquiring temperature and humidity data by using a temperature and humidity transmitter, sending the temperature and humidity data to the electric control cabinet, carrying out temperature and humidity control after threshold judgment is carried out through the electric control cabinet, and simultaneously selecting gas sterilization or liquid sterilization and a sterilization period by the electric control cabinet according to the type of an instrument or a product;
then, the ultrasonic vibrators at the bottom of the water storage box and/or the disinfectant liquid storage box are driven to carry out humidification and liquid sterilization according to the conditions selected in the previous step and the humidity data acquired by the temperature and humidity transmitter; the fog generated by the vibration of the ultrasonic vibrator is lifted up by the air exhaust fan and enters the regulating and controlling pipe through the convex pipe; when gas sterilization is carried out, sterilizing gas is injected into the gas inlet sterilizing pipeline and downwards splashed to the object placing table through the top of the small box body; meanwhile, a heating pipe array outside the regulating and controlling pipe performs PID operation according to preset temperature and real-time collected temperature so as to complete temperature response, when internal circulation is performed, an internal circulation fan pumps sterilizing gas outside the regulating and controlling pipe, heat generated by the heating pipe array and humidifying mist and sterilizing mist inside the regulating and controlling pipe to mix, the mixed gas is sent to an air inlet of an air injection ring through an internal circulation pipeline, high-heat mixed gas is injected to the top surface of the object placing table through a nozzle array on the air injection ring, the bottom surface of the object placing table is directly heated and dried through the heating pipe array, and the heated gas enters the regulating and controlling pipe again through the heating pipe array to form internal circulation; when external circulation is carried out, external gas is pumped into the regulating and controlling pipe through the air inlet valve and the tee joint, and is sent into the main oven through the external circulation pipeline and the air outlet valve after regulation and control are finished; the gas sent into the main oven is regulated and controlled by temperature, humidity and sterilization.
When the instrument or medicine raw materials need pressure regulation, sterilization and drying, the hydraulic gate valve is directly closed, the small box body or the inner box body is vacuumized through the vacuumizing pipeline, and at the moment, the small box body or the inner box body is subjected to combined temperature control or independent temperature control.
The working process of the main oven is as follows:
the main oven receives the gas sent by the condition oven, and the gas finishes temperature regulation, humidity regulation and sterilization regulation; the gas enters the annular channel and is pumped by the air exhaust fan at the top of the inner box body, so that the gas is pumped into the closed cover through the air inlet, the regulating gas is uniformly provided for the medicine raw material on the top surface of the closed cover through the grid plate at the top of the closed cover, finally, the gas returns to the conditional oven again through the open valve, the air exhaust fan and the air inlet valve, and enters the annular channel again after the environment regulation is carried out again, and a closed loop is formed; when the temperature condition collected by the temperature and humidity transmitter does not reach the drying temperature of the product, the opening degree of the opening valve is reduced until the opening degree is closed, and meanwhile, the electric heating pipe is used for heat supplement; and the circulating fan is utilized to carry out internal temperature control circulation.
The above-described embodiments are merely preferred embodiments of the present invention, and all equivalent changes or modifications of the structures, features and principles described in the claims of the present invention are included in the scope of the present invention.
Claims (7)
1. The utility model provides a GMP high temperature sterilization heated air circulation oven convenient to temperature monitoring which characterized in that: comprises an electric control cabinet controlled by the whole machine; the main drying oven is used for sterilizing and drying medicines, and the conditional drying oven is used for drying operation instruments, and the main drying oven and the conditional drying oven are closely mounted or integrally packaged through a shell;
the conditional oven comprises a small box body, and an air inlet disinfection pipeline is arranged at the top of the small box body; a water storage box and a disinfectant liquid storage box are arranged at the bottom of the small box body; the bottom of the water storage box and the bottom of the disinfectant liquid storage box are respectively provided with an ultrasonic vibrator; the inner sides of the water storage box and the disinfectant liquid storage box are respectively provided with a high-low water level probe; the end parts of the water storage box and the disinfectant liquid storage box are respectively connected to a water replenishing pipeline through a one-way valve and an electromagnetic valve; a sealing plate is fixed above the water storage box and the disinfectant liquid storage box of the small box body; the middle part of the sealing plate is provided with an air outlet; an air exhaust fan is fixed on the bottom surface of the sealing plate at the air outlet; a liquid collecting box is fixed on the top surface of the sealing plate; a liquid discharge valve is arranged at the end part of the liquid collection box; the middle part and two sides of the liquid collecting box are respectively integrally manufactured into a convex pipe with two hollow ends, and the top of the convex pipe is higher than the top surface of the liquid collecting box; the convex pipes on two sides are provided with waterproof caps; the top of the middle convex pipe is provided with a tee joint; the middle end of the tee joint is connected to an air inlet valve outside the small box body; the liquid collecting box is provided with a stress seat outside the convex pipe and the tee joint; a regulating and controlling pipe is fixed on the stress seat; the bottom of the regulating and controlling pipe is hermetically communicated with the upper end of the tee joint through an air hood; a step-shaped object placing table is arranged outside the regulating and controlling pipe; the article placing table is of a net structure; the top of the regulating and controlling pipe is closed, and a plurality of internal circulation pipelines and external circulation pipelines are embedded in the regulating and controlling pipe; the inner wall of the small box body is provided with an air injection ring in an annular or array shape opposite to the object placing table; the inner circulation pipeline is connected to the air inlet end of the air injection ring through an inner circulation fan; the external circulation pipeline is connected to an air outlet valve outside the small box body; a heating pipe array is arranged between the regulating and controlling pipe and the object placing table; the regulating and controlling pipe is provided with thermal circulation through holes at intervals; a temperature and humidity transmitter is arranged at the top of the regulating and controlling pipe;
the main oven comprises an outer box body with a hollow front end and an inner box body fixed on the inner side of the outer box body through support legs; the inner edge of the outer box body and the outer edge of the inner box body are sealed and welded through an annular sealing plate to form an annular channel; a door body is arranged on the front side of the inner box body; two rows of grid plates are fixed at two sides in the inner box body at intervals; the bottom of the grating plate and the inner side of the inner box body are provided with closed covers; an air inlet is arranged between the end part of the closed cover and the annular channel; the middle part of the bottom surface of the outer box body is communicated with an air inlet fan; the air inlet fan is connected to the air outlet valve through a pipeline; the inner box body is connected to the air inlet valve through an open valve and an air exhaust fan; the bottom of the inner box body is provided with an electric heating tube; a temperature and humidity transmitter is fixed at the upper part of the inner side of the inner box body; and an independent circulating pipeline is arranged between the bottom surface of the outer box body and the top surface of the inner box body through a circulating fan and a switch valve.
2. The GMP high temperature sterilization hot air circulation oven that facilitates temperature monitoring of claim 1, wherein: the lower part of the sealing plate of the small box body is provided with a hydraulic gate valve; the top of the small box body is connected to a vacuum-pumping pipeline through a one-way valve and a switch valve.
3. The GMP high temperature sterilization hot air circulation oven that facilitates temperature monitoring of claim 1, wherein: the annular sealing plate is welded with a frame body, and an external sealing door is arranged on the frame body.
4. The GMP high temperature sterilization hot air circulation oven that facilitates temperature monitoring of claim 1, wherein: the working process of the oven is as follows:
the condition drying oven completes sterilization and drying of instruments through internal circulation, the external circulation provides drying and sterilizing conditions for the main drying oven, and meanwhile, the condition drying oven provides pressure reduction conditions for the main drying oven through a vacuum pumping pipeline; the main oven finishes the drying of the medical products in the temperature control, humidity control, sterilization and pressure control environments.
5. The GMP high temperature sterilization hot air circulation oven that facilitates temperature monitoring of claim 1, wherein: the working process of the conditional oven is as follows:
firstly, feeding, namely respectively feeding the instrument and/or medicine raw materials into an object placing table and a grid plate; the instrument cleaning liquid is dripped into the liquid collecting box for collection and is periodically discharged outside through the liquid discharging valve; the convex pipe on the liquid collecting box prevents liquid from entering the water storage box and/or the disinfectant liquid storage box through the waterproof cap;
secondly, selecting or inputting condition control, inputting control data into the electric control cabinet through the integrated machine, simultaneously detecting and acquiring temperature and humidity data by using a temperature and humidity transmitter, sending the temperature and humidity data to the electric control cabinet, carrying out temperature and humidity control after threshold judgment is carried out through the electric control cabinet, and simultaneously selecting gas sterilization or liquid sterilization and a sterilization period by the electric control cabinet according to the type of an instrument or a product;
then, the ultrasonic vibrators at the bottom of the water storage box and/or the disinfectant liquid storage box are driven to carry out humidification and liquid sterilization according to the conditions selected in the previous step and the humidity data acquired by the temperature and humidity transmitter; the fog generated by the vibration of the ultrasonic vibrator is lifted up by the air exhaust fan and enters the regulating and controlling pipe through the convex pipe; when gas sterilization is carried out, sterilizing gas is injected into the gas inlet sterilizing pipeline and downwards splashed to the object placing table through the top of the small box body; meanwhile, a heating pipe array outside the regulating and controlling pipe performs PID operation according to preset temperature and real-time collected temperature so as to complete temperature response, when internal circulation is performed, an internal circulation fan pumps sterilizing gas outside the regulating and controlling pipe, heat generated by the heating pipe array and humidifying mist and sterilizing mist inside the regulating and controlling pipe to mix, the mixed gas is sent to an air inlet of an air injection ring through an internal circulation pipeline, high-heat mixed gas is injected to the top surface of the object placing table through a nozzle array on the air injection ring, the bottom surface of the object placing table is directly heated and dried through the heating pipe array, and the heated gas enters the regulating and controlling pipe again through the heating pipe array to form internal circulation; when external circulation is carried out, external gas is pumped into the regulating and controlling pipe through the air inlet valve and the tee joint, and is sent into the main oven through the external circulation pipeline and the air outlet valve after regulation and control are finished; the gas sent into the main oven is regulated and controlled by temperature, humidity and sterilization.
6. The GMP high-temperature sterilization heated air circulation oven that facilitates temperature monitoring of claim 5, wherein: when the instrument or medicine raw materials need pressure regulation, sterilization and drying, the hydraulic gate valve is directly closed, the small box body or the inner box body is vacuumized through the vacuumizing pipeline, and at the moment, the small box body or the inner box body is subjected to combined temperature control or independent temperature control.
7. The GMP high temperature sterilization hot air circulation oven that facilitates temperature monitoring of claim 1, wherein: the working process of the main drying oven is as follows:
the main oven receives the gas sent by the condition oven, and the gas finishes temperature regulation, humidity regulation and sterilization regulation; the gas enters the annular channel and is pumped by the air exhaust fan at the top of the inner box body, so that the gas is pumped into the closed cover through the air inlet, the regulating gas is uniformly provided for the medicine raw material on the top surface of the closed cover through the grid plate at the top of the closed cover, finally, the gas returns to the conditional oven again through the open valve, the air exhaust fan and the air inlet valve, and enters the annular channel again after the environment regulation is carried out again, and a closed loop is formed; when the temperature condition collected by the temperature and humidity transmitter does not reach the drying temperature of the product, the opening degree of the opening valve is reduced until the opening degree is closed, and meanwhile, the electric heating pipe is used for heat supplement; and the circulating fan is utilized to carry out internal temperature control circulation.
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| CN202110100936.1A CN112629187B (en) | 2021-01-26 | 2021-01-26 | GMP high temperature sterilization heated air circulation oven convenient to temperature monitoring |
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- 2021-01-26 CN CN202110100936.1A patent/CN112629187B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20160084136A (en) * | 2015-01-05 | 2016-07-13 | (주) 토모우드 | Method and apparatus for drying domestically produced wood using check of water content |
| CN204535280U (en) * | 2015-02-09 | 2015-08-05 | 深圳市瑞昇新能源科技有限公司 | Online rapid vacuum drying case |
| CN206583222U (en) * | 2017-02-16 | 2017-10-24 | 天津再生缘生物科技有限公司 | A kind of food processing vacuum microwave drying sterilizing installation |
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| CN112629187B (en) | 2021-09-07 |
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