CN112585259A - 用于自动细胞培养的系统和方法 - Google Patents

用于自动细胞培养的系统和方法 Download PDF

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CN112585259A
CN112585259A CN201980054549.XA CN201980054549A CN112585259A CN 112585259 A CN112585259 A CN 112585259A CN 201980054549 A CN201980054549 A CN 201980054549A CN 112585259 A CN112585259 A CN 112585259A
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cell culture
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A·阿夫沙尔
J·康宁汉姆
H·米斯金
I·威拉茨
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Cela Cell Engineering Co ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00663—Quality control of consumables
    • G01N2035/00673—Quality control of consumables of reagents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201980054549.XA 2018-08-19 2019-08-19 用于自动细胞培养的系统和方法 Pending CN112585259A (zh)

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US201862719652P 2018-08-19 2018-08-19
US62/719,652 2018-08-19
PCT/EP2019/072115 WO2020038874A1 (en) 2018-08-19 2019-08-19 Systems and methods for automated cell culturing

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EP (1) EP3837347A1 (enExample)
JP (2) JP7496815B2 (enExample)
CN (1) CN112585259A (enExample)
CA (1) CA3109425A1 (enExample)
WO (1) WO2020038874A1 (enExample)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN115125127A (zh) * 2022-07-13 2022-09-30 广州逆熵电子科技有限公司 一种微生物生长全周期的观察方法及装置
CN116396851A (zh) * 2023-03-23 2023-07-07 扬朋科技股份有限公司 细胞制备系统

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US12233408B2 (en) * 2018-12-05 2025-02-25 Arizona Board Of Regents On Behalf Of The University Of Arizona Smart storage container for health logistics
WO2021195391A1 (en) * 2020-03-27 2021-09-30 Broadley-James Corporation Single-use bioreactor assembly with integrated pump heads
CN114149917A (zh) * 2021-11-15 2022-03-08 安徽骆华生物科技有限公司 一种一体化活细胞工作站
WO2024030517A1 (en) * 2022-08-02 2024-02-08 Analog Devices, Inc. Biological specimen incubator with gas sensor
EP4638692A2 (en) * 2022-12-20 2025-10-29 Analog Devices, Inc. Biological specimen imaging unit for use in incubator
WO2025006358A1 (en) * 2023-06-29 2025-01-02 Illumina, Inc. Systems and related reagent cartridge queuing methods
DE102024121070A1 (de) * 2024-07-24 2026-01-29 Hamilton Bonaduz Ag Zellkultur-Bewirtschaftungsvorrichtung mit Medienförderung zwischen Zellkulturbehältern und Verfahren für einen Medientransfer zwischen Zellkulturbehältern
WO2026022007A1 (de) 2024-07-24 2026-01-29 Hamilton Bonaduz Ag Zellkulturbehälter-betriebseinrichtung zur sicheren lösbaren aufnahme eines zellkulturbehälters während einer zellkultur-bewirtschaftung
DE102024121069A1 (de) * 2024-07-24 2026-01-29 Hamilton Bonaduz Ag Medienbehältersystem für eine Zellkultur-Bewirtschaftungsvorrichtung
DE102024121072A1 (de) 2024-07-24 2026-01-29 Hamilton Bonaduz Ag Taumelvorrichtung für eine Zellkultur-Bewirtschaftungsvorrichtung zur Benetzung von Oberflächen in einem Zellkulturbehälter
DE102024121067A1 (de) * 2024-07-24 2026-01-29 Hamilton Bonaduz Ag Zellkultur-Bewirtschaftungsvorrichtung mit einer Ventilblockanordnung mit wenigstens zwei gesondert voneinander ausgebildeten Ventilblöcken
TWI924593B (zh) * 2025-09-18 2026-05-01 國立清華大學 模組化培養箱

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CN115125127A (zh) * 2022-07-13 2022-09-30 广州逆熵电子科技有限公司 一种微生物生长全周期的观察方法及装置
CN116396851A (zh) * 2023-03-23 2023-07-07 扬朋科技股份有限公司 细胞制备系统

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JP7496815B2 (ja) 2024-06-07
US12221600B2 (en) 2025-02-11
US10988726B2 (en) 2021-04-27
CA3109425A1 (en) 2020-02-27
WO2020038874A1 (en) 2020-02-27
US20200056140A1 (en) 2020-02-20
US20210238532A1 (en) 2021-08-05
JP2021533739A (ja) 2021-12-09
JP7798961B2 (ja) 2026-01-14
JP2024122999A (ja) 2024-09-10
EP3837347A1 (en) 2021-06-23
US20250002835A1 (en) 2025-01-02

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