CN112545940A - Hand and nail cream and preparation method thereof - Google Patents
Hand and nail cream and preparation method thereof Download PDFInfo
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- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/345—Alcohols containing more than one hydroxy group
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Abstract
The application relates to the field of hand skin care products, and particularly discloses hand and nail protection cream and a preparation method thereof. The hand and nail protection cream comprises the following components in percentage by weight: the balance of water; group A: 3-8% of a humectant; 0.1 to 0.5 percent of thickening agent; 0.3 to 1 percent of calcium pantothenate; group B: 5-15% of an emollient; 10-18% of a first conditioner; 1-3% of a second conditioner; 1-3% of a first emulsifier; 0.2-0.5% of second emulsifier; 0.5 to 5 percent of emulsion stabilizer; group C: 0.05 to 0.3 percent of dimethyl sulfone; 0.5-4% of a third conditioner; 0.1-8% of a fourth conditioner; 3.5 to 7 percent of fifth conditioner; 2-6% of antibacterial and anti-allergic agent; 0.1 to 0.3 percent of preservative; the third conditioner is at least one of hydrolyzed silk and birch bark extract. The hand and nail protection cream can be used for hand care, and has the advantage of achieving the care of nails and surrounding skin while caring the skin of hands.
Description
Technical Field
The application relates to the field of hand skin care products, in particular to hand and nail protection cream and a preparation method thereof.
Background
With the progress of society and the development of times, people pay more and more attention to the care of their skin, not only the face but also the hands, and from the earliest, only facial skin care products are popularized to the hand cream specially used for the hands at present in daily life.
In the related technology, the main components of the hand cream are mainly water phase components, oil phase components, emulsifiers and other components, including emollients, humectants, water, emulsifiers and the like, so that the balance of skin moisture is kept, important oily components, hydrophilic moisturizing components and moisture are supplemented, and the rough and dry hand cracks in autumn and winter are effectively prevented and treated.
In the related art, the hand cream mainly treats hand skin, and the stimulation of the external environment can cause nails to become brittle, age or lose luster, so that the skin on the nails floats; the nail is a part of the hand, and the hand cream of the related art has no care effect on the nail and the surrounding skin.
Disclosure of Invention
In order to realize the nursing of the fingernails and the surrounding skin while nursing the skin of the hands, the application provides hand and nail protection cream and a preparation method thereof.
In a first aspect, the present application provides the following technical solutions: the hand and nail cream comprises the following components in percentage by weight:
the balance of water;
group A:
3-8% of a humectant;
0.1 to 0.5 percent of thickening agent;
0.3 to 1 percent of calcium pantothenate;
group B:
5-15% of an emollient;
10-18% of a first conditioner;
1-3% of a second conditioner;
1-3% of a first emulsifier;
0.2-0.5% of second emulsifier;
0.5 to 5 percent of emulsion stabilizer;
group C:
0.05 to 0.3 percent of dimethyl sulfone;
0.5-4% of a third conditioner;
0.1-8% of a fourth conditioner;
3.5 to 7 percent of fifth conditioner;
2-6% of antibacterial and anti-allergic agent;
0.1 to 0.3 percent of preservative;
the third conditioner is at least one of hydrolyzed silk and birch bark extract.
By adopting the technical scheme, the water provides a carrier for the whole formula, and the carrier with certain viscosity is formed after the water reacts with the thickening agent. The moisturizer provides moisturizing effect for skin, reduces the loss of moisture on the surface of hand skin and reduces hand dryness; emollients enhance the skin's moisturizing ability, moisturize cutin-damaged skin, and provide excellent feel and extensibility to the product. The first emulsifier, the second emulsifier and the emulsion stabilizer can well mix the hydrophilic component and the lipophilic component to obtain a uniform and stable product. The first, second, third, fourth and fifth conditioning agents provide nutrients and conditioning to the skin. The antibacterial and anti-allergic agent can reduce bacteria breeding of the product and reduce anaphylactic reaction, and the preservative can prolong the storage time of the product.
Calcium pantothenate is easily soluble in water and glycerol, has hygroscopic property, and has moisture keeping effect. Dimethyl sulfone is dissolved in water, is an essential substance for human collagen synthesis, is contained in tissues such as human skin, hair, nails, bones, muscles and the like, and is a main substance for maintaining biological sulfur balance of a human body.
The hydrolyzed silk is natural polymer fibrin extracted from silk, the content of the natural polymer fibrin accounts for about 70-80% of the silk, the hydrolyzed silk contains 18 amino groups, the synthesis of collagen can be promoted, the damaged skin tissue can be helped to be repaired, and the hydrolyzed silk can be used as a humectant and a skin conditioner. The cortex Betulae Pendulae extract can inhibit histamine release, and has antiallergic effect; has inhibiting effect on elastase and metalloprotease, and has good antiaging effect.
Tests show that in addition to caring the hand skin, when calcium pantothenate, dimethylsulfone and a third conditioner are used in combination, the nail care can be realized, the glossiness and smoothness of the nail can be improved, the skin on the coated nail can be effectively nursed, and the condition that the skin on the nail floats and peels off can be reduced and slowed down. Further, the mass part ratio of the calcium pantothenate to the dimethyl sulfone is (5-8): 1.
by adopting the technical scheme, tests show that the calcium pantothenate and the dimethyl sulfone in the preferred ranges can achieve better nail and skin care effects on the nails after being matched with the third conditioner.
Further, the third conditioner is prepared from the following components in parts by weight of 1: (0.9-1) hydrolyzed silk and birch bark extract.
By adopting the technical scheme, experiments show that the third conditioning agent in the preferable range has better matching effect with calcium pantothenate and dimethyl sulfone.
Further, the mass part ratio of the dimethyl sulfone to the third conditioner is 1: (8-10).
By adopting the technical scheme, experiments show that the dosage proportion of the third conditioning agent and the dimethyl sulfone in the preferable range enables the matching effect of the calcium pantothenate, the dimethyl sulfone and the third conditioning agent to be better.
Further, the fifth conditioner consists of 3-8% of ceramide 2, 32-40% of phytosterol, 10-35% of glycerol, 10-18% of polyglycerol-6 laurate and the balance of water.
By adopting the technical scheme, the ceramide 2 is a main component of human skin and hair, and can be used as a moisturizing agent, a skin conditioner and an antioxidant; can improve the sebaceous membrane and inhibit the secretion of active sebaceous glands at the same time, so as to balance the water and oil of the skin. Phytosterols extracted from plants has surfactant property, antioxidant and antiaging effects, and is also a nutritional agent, and has effects of promoting keratin and fibroblast proliferation and promoting collagen synthesis. Polyglycerol-6 laurate has excellent solubilizing, emulsifying, dispersing and lubricating abilities, and glycerol has good moisture-retaining properties and can be used as a base material, an emollient, a lubricant and a solvent. As can be seen from the tests, the fifth conditioning agent is defined, so that the care effect of the product on the nails and the skin on the nails can be further enhanced. Further, the mass part ratio of the third conditioner to the fifth conditioner is 1: (3.5-7).
By adopting the technical scheme, tests show that the dosage proportion of the third conditioning agent and the fifth conditioning agent in the preferable range can further improve the care effect of the product on the nails and the skin on the nails.
Further, the first conditioner consists of squalane accounting for 8-15% of the total weight of the hand and nail care cream, saw palmetto seed fat accounting for 0.5-2% of the total weight of the hand and nail care cream and citronella leaf oil accounting for 0.01-0.15% of the total weight of the hand and nail care cream.
By adopting the technical scheme, squalane has better antioxidation, can be rapidly dissolved with moisture and grease in skin, and forms a natural skin protection barrier; the skin care liquid has good stability, can effectively protect the skin from being damaged by external substances, has good permeability, can adjust the water-oil balance of the skin, avoids the skin from being rough and dark, and enables the skin to recover the original tender touch feeling. The malus lucidus seed fat can improve the capability of skin to absorb nutrients and moisture, and can better protect the skin under severe environments such as high temperature, high pressure, dryness and the like so as to keep the skin tender and smooth. The lemongrass leaf oil has strong fresh fragrance, improves the sensory quality of the lemongrass leaf oil, and has an antibacterial effect. The first conditioning agent can provide good moisturizing and skin lubricating effects for the product.
In a second aspect, the present application provides the following technical solutions: a preparation method of hand and nail cream comprises the following steps:
s1: heating water to 100 ℃, cooling to 70-75 ℃, preserving heat, adding the raw materials in the group A, and uniformly mixing to obtain a water phase component;
s2: mixing the raw materials of group B, heating to 70-75 ℃, preserving heat, and uniformly mixing to obtain an oil phase component;
s3: adding the oil phase component into the water phase component while stirring, and homogenizing for 5-10min after the addition is completed to obtain a mixed phase;
s4: and (3) adding each raw material of the phase C raw material into the mixed phase respectively, stirring while adding, uniformly stirring after adding, vacuumizing, and discharging to obtain the hand and nail cream.
The steps S1 and S2 have no requirement of precedence order.
By adopting the technical scheme, uniform and stable hand and nail cream is obtained.
In summary, the present application has the following beneficial effects:
1. the application preferably adopts the compounding of calcium pantothenate, dimethyl sulfone and a third conditioning agent, so that the effects of improving the glossiness and smoothness of the nails, effectively nursing the skin on the coated nails and reducing and slowing down the floating and stripping of the skin on the nails are achieved.
2. In the application, hydrolyzed silk and birch bark extract are preferably adopted to form the third conditioner, the third conditioner has better matching effect with calcium pantothenate and dimethyl sulfone, and the effect on nails and nail skin is further improved.
3. The application preferably uses a fifth conditioner consisting of 3-8% ceramide 2, 32-40% phytosterols, 10-35% glycerin, 10-18% polyglycerol-6 laurate and the balance water to further enhance the care of the product on the nails and skin on the nails.
Detailed Description
Examples
Examples 1 to 16: a hand and nail cream, examples 1-5 include the components, compositions and corresponding masses shown in Table 1.1, examples 6-11 include the components, compositions and corresponding masses shown in Table 1.2, examples 12-16 include the components, compositions and corresponding masses shown in Table 1.3, and is prepared by the following steps:
s1: adding water into a first stirring pot, heating to 100 deg.C, stopping heating, cooling to 70 deg.C, maintaining the temperature, adding group A raw materials, and stirring at 50r/min for 5min to obtain water phase component;
s2: putting the raw materials in the group B into a second stirring pot, heating to 70 ℃, preserving heat, and stirring for 10min at the speed of 70r/min to obtain an oil phase component;
s3: adding an oil phase component into the water phase component of the first stirring pot, keeping stirring during adding, completing adding of the oil phase component within 5min, and then mixing for 10min at a stirring speed of 500r/min to obtain a mixed phase;
s4: adding each raw material of the phase C raw material into a mixed phase in a first stirring pot respectively, keeping stirring when adding, and stirring for 10min at 120r/min after adding; vacuumizing, cooling and discharging, and inspecting to be qualified to obtain the hand and nail cream.
Steps S1 and S2 are not required in a sequential order.
TABLE 1.1 examples 1-5 compositions, compositions and corresponding masses (kg)
TABLE 1.2 examples 6-11 compositions, compositions and corresponding masses (kg)
TABLE 1.3 examples 12-16 compositions, compositions and corresponding masses (kg)
In the above examples, the humectant is glycerin and the thickener is carbomer.
The emollient is composed of chinaroot greenbrier seed oil, shea butter and argania spinosa kernel oil in a mass ratio of 3:2: 3.
The first emulsifier is composed of PEG-100 stearate and glyceryl stearate with the mass part ratio of 1: 1. The second emulsifier consists of 37.5% sodium acrylate/sodium acryloyldimethyl taurate copolymer, 22.5% isohexadecane, 7.5% polysorbate-80, 2.5% sorbitan oleate and balance water. The emulsion stabilizer is behenyl alcohol.
The second conditioner comprises 50% of jojoba esters, 40% of sunflower seed wax, 5% of green wattle flower wax and the balance of polyglycerol-3. The fourth conditioner consisted of 27.5% vaccinium myrtillus fruit/leaf extract, 12.5% sugar cane extract, 5% orange fruit extract, 5% lemon fruit extract, 2% maple extract, and the balance water.
The antibacterial and anti-allergy agent consists of a filtrate of a fermentation product of the leuconostoc/radish root and water, wherein the mass part ratio of the filtrate to the filtrate is 1: 1. The preservative consisted of 30% ethylhexyl glycerol and the balance octyl glycol.
Example 17: a preparation method of hand and nail cream comprises the following steps:
s1: adding water into a first stirring pot, heating to 100 deg.C, stopping heating, cooling to 75 deg.C, maintaining the temperature, adding group A raw materials, and stirring at 50r/min for 8min to obtain water phase component;
s2: putting the raw materials in the group B into a second stirring pot, heating to 75 ℃, preserving heat, and stirring for 10min at the speed of 70r/min to obtain an oil phase component;
s3: adding an oil phase component into the water phase component of the first stirring pot, keeping stirring during adding, completing adding of the oil phase component within 5min, and then mixing for 8min at a stirring speed of 600r/min to obtain a mixed phase;
s4: adding each raw material of the phase C raw material into a mixed phase in a first stirring pot respectively, keeping stirring when adding, and stirring for 10min at 120r/min after adding; vacuumizing, cooling and discharging, and inspecting to be qualified to obtain the hand and nail cream.
The steps S1 and S2 have no requirement of precedence order.
Comparative example
Comparative example 1: a hand and nail cream differing from example 1 in that the calcium pantothenate and dimethyl sulfone are replaced by equal amounts of humectant and the tertiary conditioner is replaced by equal amounts of the primary conditioner.
Comparative example 2: a hand and nail cream which differs from example 1 in that the third conditioning agent is replaced by an equal amount of the first conditioning agent.
Comparative example 3: a hand and nail cream which differs from example 1 in that dimethyl sulfone is replaced with an equal amount of humectant.
Comparative example 4: a hand and nail cream differing from example 1 in that calcium pantothenate was replaced with an equal amount of humectant.
Comparative example 5: a hand and nail cream which differs from example 1 in that the third conditioning agent is Aloe ferox extract.
Characterization test:
1. quality testing test
Test subjects: examples 1-16, for a total of 16 test samples.
The test method comprises the following steps: according to the light industry standard QB/T1857-:
appearance: the paste is fine and uniform; fragrance: the odor type accords with the specified odor type; pH: 4.0-8.5, the range is qualified.
Heat resistance: (40 +/-1) keeping for 24 hours, and after the paste body is recovered to the room temperature, the paste body has no water separation phenomenon, and the paste body is qualified if the paste body is not separated; cold resistance: keeping the temperature of-5 to-10 ℃ for 24h, and having no obvious shape difference after the temperature is restored to the room temperature and before the test, if not, the product is qualified.
Centrifuging: centrifuging at 3000r/min for 30min, and observing whether layering exists or not and demulsification phenomenon exists; if not, the product is qualified.
Pass was rated as O and fail was rated as X.
And (3) test results: the quality test results are reported in table 2.
TABLE 2 quality test results
And (3) data analysis: as can be seen from Table 2, the quality tests of examples 1 to 16 all met the industry requirements.
2. Sensory Scoring test
Test samples: examples 1-16 and comparative examples 1-5, for a total of 21 test samples.
The test method comprises the following steps: randomly selecting a female with age of 24-32 years, no allergy history and no obvious trauma to hands. And determining the total score of the hand and nail protection cream by taking the extension degree of the cream, the viscosity degree of the cream, the moistening degree and the moistening maintenance degree as evaluation standards. Five women were in one group, each group corresponding to examples 1-16 and comparative examples 1-5, respectively; before the hand and nail protection cream is used, a pump of hand sanitizer (Aloe ferox antibacterial hand sanitizer; specification: 500 g/bottle) is used, washed by clean water and finally wiped dry. The average of the total scores given to each group of five women was calculated and recorded as the final score for the test sample.
Paste ductility: good extensibility (16-20), general extensibility (10-15) and poor extensibility (0-10);
paste viscosity: the hands are fresh and cool without stickiness (16-20), the paste is not fresh and cool (10-15) and the paste is sticky (0-10);
moistening degree: the moistening effect is good (21-30), the moistening effect is general (11-20), and the moistening effect is not obvious (0-10);
moisture retention degree: the moistening and maintaining time is long (16-20), the moistening and maintaining time is general (10-15), and the moistening and maintaining time is short (0-10).
And (3) test results: sensory score test results are reported in table 3.
TABLE 3 sensory Scoring test results
And (3) data analysis: as can be seen from the data in Table 3, examples 1 to 16 and comparative examples 1 to 5 performed well on the total score, and achieved good spread, stickiness, moisture and moisture retention of the cream. The poor overall score of comparative example 1 indicates that the combination of calcium pantothenate, dimethyl sulfone, and a third conditioning agent will have a small impact on the sensory score of the hand and nail cream.
3. Test for nail protection Effect
Test samples: examples 1-16 and comparative examples 1-5, for a total of 21 test samples.
The test method comprises the following steps: randomly selecting female with age of 24-32 years, no allergy history, no obvious wound on hand, dark nail or floating skin on nail or both of the above cases; each test sample was tested against three women.
Recording the type of the condition of each female in the early period and the degree grade of the condition; in case types, a is dull and lusterless nail, b is superficial and superficial skin on nail, ab is both cases; of the three women corresponding to each sample specimen, the case types of three persons cannot be all a or all b. The degree scale includes a scale of 0-5, from 0 to 5, with progressively increasing degrees of nail darkening and skin lifting on the nail. After the application for 14 days, the hands feel dry and are smeared, and the degree grade of the corresponding situation is improved after 30 days.
And (3) test results: the results of the armor effectiveness test are reported in table 4.
Table 4 nail protection effectiveness test results
And (3) data analysis: as is clear from the data in Table 4, examples 1-16 exhibited a certain reduction in both dullness and floating of the skin on the nails, and examples 8-16, particularly examples 11-16, exhibited very good results in terms of care. Comparative examples 1 to 5 had little effect on cases a, b, ab.
Comparing all the examples, examples 1-3 have improved a and b cases, examples 4-5 have defined the compounding amount of calcium pantothenate and dimethyl sulfone based on example 3, examples 6-7 have defined the composition of the third conditioning agent based on example 5, and the improvement of a and b cases is improved. Examples 8 to 9 define the combination of dimethyl sulfone and the third conditioning agent on the basis of example 7, and further improve the situation improvement effect. The reasons may be: the fifth conditioner can moisten and permeate the protective film on the nail surface and the skin on the bracket, and promote the entry and absorption of effective components; in addition, the composition of the fifth conditioner can form high-concentration packages, and the effective stable dosage form ensures that the function of the ceramide is optimized.
Examples 10 to 11 define the composition of the fifth conditioning agent on the basis of example 9, and examples 12 to 13 define the combined amount of the fifth conditioning agent and the third conditioning agent on the basis of example 11, thereby further improving the situation improvement effect. Examples 14-16 define a third conditioning agent and a fifth conditioning agent on the basis of example 13, which, with reference to trial 1, can improve the sensory use of the product while achieving an improvement in ab status. The reasons may be: the third conditioner is beneficial to promoting the action and absorption of calcium pantothenate and dimethyl sulfone, and improving the utilization efficiency of effective components; the third conditioning agent, calcium pantothenate and dimethylsulfone can promote the growth of the nail-skin junction, improve the adhesion, and care the skin and nail, thereby achieving the care of the nail and the skin on the nail.
Comparative example 1 and comparative examples 1-5, comparative example 1 did not use a combination of calcium pantothenate, dimethyl sulfone, and a third conditioning agent, and had no improvement effect on a, b, and ab conditions. Comparative example 2 no third conditioner was used, and comparative example 5 replaced the third conditioner with aloe ferox extract, which is a minor improvement to a certain degree of the grade, indicating that the formulation of the third conditioner with calcium pantothenate, dimethyl sulfone can greatly enhance the care of the product for the nail and the skin on the nail. Comparative example 3, which uses no dimethyl sulfone, and comparative example 4, which uses calcium pantothenate, has little effect, indicating that a combination with a third conditioner, based on calcium pantothenate and dimethyl sulfone, has good effect.
The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.
Claims (8)
1. The hand and nail cream is characterized by comprising the following components in percentage by weight:
the balance of water;
group A:
3-8% of a humectant;
0.1 to 0.5 percent of thickening agent;
0.3 to 1 percent of calcium pantothenate;
group B:
5-15% of an emollient;
10-18% of a first conditioner;
1-3% of a second conditioner;
1-3% of a first emulsifier;
0.2-0.5% of second emulsifier;
0.5 to 5 percent of emulsion stabilizer;
group C:
0.05 to 0.3 percent of dimethyl sulfone;
0.5-4% of a third conditioner;
0.1-8% of a fourth conditioner;
3.5 to 7 percent of fifth conditioner;
2-6% of antibacterial and anti-allergic agent;
0.1 to 0.3 percent of preservative;
the third conditioner is at least one of hydrolyzed silk and birch bark extract.
2. The hand and nail cream as claimed in claim 1, wherein the mass part ratio of the calcium pantothenate to the dimethyl sulfone is (5-8): 1.
3. the hand and nail cream as claimed in claim 1, wherein the third conditioning agent is prepared from the following components in parts by weight of 1: (0.9-1) hydrolyzed silk and birch bark extract.
4. The hand and nail cream as claimed in claim 3, wherein the mass part ratio of the dimethyl sulfone to the third conditioner is 1: (8-10).
5. A hand and nail cream according to claim 1 or 3, characterised in that the fifth conditioning agent consists of 3-8% ceramide 2, 32-40% phytosterols, 10-35% glycerol, 10-18% polyglycerol-6 laurate and the balance water.
6. The hand and nail cream as claimed in claim 4, wherein the ratio of the third conditioner to the fifth conditioner in parts by weight is 1: (3.5-7).
7. The hand and nail cream as claimed in claim 1, wherein the first conditioner consists of squalane accounting for 8-15% of the total weight of the hand and nail cream, pluronic palm seed fat accounting for 0.5-2% of the total weight of the hand and nail cream and citronella leaf oil accounting for 0.01-0.15% of the total weight of the hand and nail cream.
8. A process for the preparation of a hand and nail cream according to any one of claims 1 to 7, characterised in that it comprises the steps of:
s1: heating water to 100 ℃, cooling to 70-75 ℃, preserving heat, adding the raw materials in the group A, and uniformly mixing to obtain a water phase component;
s2: mixing the raw materials of group B, heating to 70-75 ℃, preserving heat, and uniformly mixing to obtain an oil phase component;
s3: adding the oil phase component into the water phase component while stirring, and homogenizing for 5-10min after the addition is completed to obtain a mixed phase;
s4: adding each raw material of the phase C raw material into the mixed phase respectively, stirring while adding, uniformly stirring after adding, vacuumizing, and discharging to obtain the hand and nail cream;
the steps S1 and S2 have no requirement of precedence order.
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