CN110179710A - A kind of infant's skin cream of the ingredient containing antipollution - Google Patents
A kind of infant's skin cream of the ingredient containing antipollution Download PDFInfo
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- CN110179710A CN110179710A CN201910539518.5A CN201910539518A CN110179710A CN 110179710 A CN110179710 A CN 110179710A CN 201910539518 A CN201910539518 A CN 201910539518A CN 110179710 A CN110179710 A CN 110179710A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
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Abstract
The present invention discloses a kind of infant's skin cream of ingredient containing antipollution, includes: at least containing a kind of emulsifier of mild plant origin;At least containing a kind of soft, the mild vegetable oil of moist non-greasy;At least there is significant convergence, the mild grease of anti-chap containing a kind of;At least there is significant moistening effect, the mild grease of high-quality skin sense containing a kind of;At least contain a kind of plant extracts with significant antipollution effect;Not only property is mild by the present invention, low stimulation, but also has good ph stability and the superperformances such as heat-resisting that resist cold.
Description
Technical field
The present invention relates to infant's skin cream more particularly to a kind of infant's skin cream of ingredient containing antipollution.
Background technique
The skin texture of infant is not yet developed completely, does not have many functions of adult skin.Infant and at fell
Skin has certain difference, and under normal circumstances, infant's skin area and body weight ratio are about 500:1, and adult is but 270:1.
It can be seen that baby's skin area and body weight ratio are twice than adult.Skin area and body weight ratio are big, skin fat phase
It should increase, it is also more to absorb chemical substance.The development degree of infant's skin is low, so that the immune system of baby is weak, does not grow up
The ability of people resistance bacterial virus.To keep baby's skin moisturizing smooth elastic, the most upper one layer of acidity of skin can only be passed through
Skin membrane is protected.Once skin is easy to the allergy such as erythema, erythema, bubble occur by bacterial invasion without this layer of protective film
Symptom.The skin of baby top layer is made of unicellular cuticula, is contained a small amount of fiber, is lacked elasticity, thickness is only adult
1/10.In addition, because baby's subcutaneous fat is few, it is easier to be lost moisture, skin typically exhibits out relatively dry state.Cause
This, they do not resist dry ability, and are easily injured by extraneous penetration toxic or excitatory.So protecting
The skin of baby has been protected, has selected a suitable baby to use, mild, the dedicated skin-protection product of the baby without allergy, antipollution formula
It is particularly important.
2015, bavin quiet " Under the Dome " was thoroughly ignited the haze problem that people originally pay close attention to, all kinds of resistance hazes
Topic be also unfolded immediately.In fact, the problem of not only haze, all kinds of pollutions in life also become people's worry further.
People recognize to resist pollution gradually also while resisting pollution, conservation of nature environment to protect oneself
Skin, consumer are also growing day by day for the consciousness and demand of antipollution cosmetics.Just because of such reason, antipollution makeup
Huge potentiality are contained in product market.
Domestic and international multiple research institutes, hospital and university at present, such as German Leibniz Institute of Environmental Medicine, upper marine growth
Science Institute, The Third Affiliated Hospital of Peking University, Fudan University's Life Science College etc., the influence in environment to skin and work
Numerous studies, such as the influence of urban air pollution, traffic pollution, pollution that caused by coal burning to skin have been done with mechanism aspect.And one
A little international well-known cosmetics companies have also carried out the correlative study of influence of the air pollution to skin, and are dedicated to antipollution makeup
The research and development of product.Therefore, resistant to pollution cosmetics comply with trend and come into being.The product contains antipollution ingredient, and has through detection
There is antipollution effect, there is reliable safety in utilization.
Summary of the invention
To overcome above-mentioned deficiency, the present invention provides a kind of infant's skin cream of ingredient containing antipollution.
The technical solution adopted by the present invention to solve the technical problems is: a kind of infant's moisturizing of the ingredient containing antipollution
Frost, which is characterized in that be grouped as comprising following group by weight percentage:
Water/stearoyl dilactic acid sodium/sucrose polyoleate 2%~5%;
Olive oil 0.1%~5%;
Lanolin 0.1%~5%;
Caprylic/capric triglyceride 5%~15%;
Camellia flower extract 0.1%~2%;
Ethylhexyl palmitate, beeswax combination object 4%~8%;
Natrulon H-10 1.0%~5.0%;
Glycerol 10%~20%;
Carbohydrate isomer 0.1%~0.5%;
Ammonium acryloyl taurate/VP copolymer 0.15%~0.3%;
Phenoxyethanol and parahydroxyacet-ophenone 0.1%~1.0%;
Deionized water adds to 100%.
Both Phenoxyethanols and parahydroxyacet-ophenone ratio is about 1:2.
Detailed description of the invention:
Fig. 1 is skin wound repair grade form.
Fig. 2 is skin irritatin strength grading table.
Fig. 3 is skin irritatin strength test results table.
Specific embodiment:
Below with reference to embodiment to further detailed description of the present invention, embodiments of the present invention are not limited thereto.
Embodiment 1
Raw material are pressed into following proportional arrangement
The purpose of the present invention is to provide a kind of infant's skin cream of ingredient containing antipollution, it contain substantially under
Column material composition: at least contain a kind of emulsifier of mild plant origin;It is at least soft containing one kind, moisten the mild of non-greasy
Vegetable oil;At least there is significant convergence, the mild vegetable oil of anti-chap containing a kind of;At least there is significant moisturizing effect containing a kind of
Fruit, the mild grease of high-quality skin sense;At least contain a kind of plant extracts with significant antipollution effect;In addition, it is also wrapped
It includes, moisturizer, thickener, preservative, chelating agent and deionized water etc..We have found that not only property is mild, low stimulation by the present invention,
But also there is good ph stability and the superperformances such as heat-resisting that resist cold.
The detailed description of preferred technical solution
The first ingredient of the invention is the emulsifier at least containing a kind of mild plant origin.Water (and) stearoyl lactoyl
Sodium lactate (and) sucrose polyoleate, it is the raw material of a compounding.Wherein, stearoylketene dilactic acid sodium, by stearic acid and lactic acid
Prepared by middle synthesis sodium salt, extensively with forFood additives, Flour product, dairy products, chocolate and various candies, jam,
It can be added in the food product making process such as catsup, sweet fermented flour sauce.Therefore it is mild safety that the emulsifier, which is used in cosmetics,.
Sucrose polyoleate is to carry out esterification using sucrose as raw material with oleic acid and generate.Since sucrose ester is closer in performance
The sebum of human secretory, it is nonirritant, it can be used for the emulsifier of various essence, shampoo, face cream, lipstick etc., can increase skin
The smoothness of skin and sliding tender sense, prevent precipitation of grease in cosmetics, improve the washing performance of cosmetics.Relevant information shows addition
The cosmetics of sucrose ester have become the main product of international market.Therefore the emulsification of currently preferred mild plant origin
Agent is water (and) stearoyl dilactic acid sodium (and) sucrose polyoleate.
Second of ingredient of the invention is at least containing soft, the mild vegetable oil of moist non-greasy.Olive oil is
As made of the fresh direct cold press of olive fruit, not heated and chemical treatment remains natural nutrient component.Olive
Fruit oil is considered as the grease olive oil that human nutrition is most suitable in the grease found so far, is rich in and skin affinity
Splendid squalene and essential fatty acid, absorption rapidly, effectively keep skin elasticity and moisten;It is contained in olive oil
Monounsaturated fatty acids and vitamin E abundant, K, A, D etc. and phenols antioxidant, can eliminate facial wrinkles, prevent skin
Aging, skin or hair care and other effects are the cosmetics and skincare products that " can be eaten ".Therefore currently preferred soft, it moistens and non-greasy
Mild vegetable oil be olive oil.
The third ingredient of the invention contains a kind of with significant convergence, the mild grease of anti-chap.Lanolin is attachment
A kind of secretion grease on wool, main component are the fat of sterols, fatty alcohols and triterpene alcohols and about equivalent
Acid ester generated.Lanolin can allow skin smooth tender, can make to dry because lacking natural moisture or rough skin is soft
Changing and being restored is excellent moistness substance.It is rather than moisture to be prevent completely to tie up through epidermis by delay
Hold the common water content of skin.Therefore currently preferred significant convergence, the mild grease of anti-chap are lanolin.
4th kind of ingredient of the invention is that at least have significant moistening effect, the mild grease of high-quality skin sense containing a kind of.
Caprylic/capric triglyceride is colourless, tasteless, and chemical property is inert, and stable chemical performance, shiny appearance is transparent, with other oil
Rouge has good intermiscibility.Caprylic/capric triglyceride can provide good skin sense, and another skin is smooth and without stagnant sense after,
And there is excellent anti-oxidant and thermal stability, and it is very safe, skin is not stimulated, not sensitization, is highly recommended for baby
In care product.Therefore currently preferred to have significant moistening effect, the mild grease of high-quality skin sense is caprylic/capric glycerol
Three esters.
5th kind of ingredient of the invention is at least to contain a kind of plant extracts with significant antipollution effect.Camellia
Extract, main antioxidant component includes Quercetin, isoquercitrin, Quercetin and Kaempferol etc. in camellia.These ingredients can
By remove human keratinous is formationed reactive oxygen species ROS and enhancing activities of antioxidant enzymes thus reach oxidation resistant DPPH and
ABTS free radical scavenging ability.2016, South Korea scholar Scoungwoo Shin research discovery camellia flower extract had good
Free radical scavenging ability, it is living that MMP-1 matrix metalloproteinase can be effectively reduced while increasing skin type I collagen content
Property, the compact degree and moisture of skin are kept, and the oxidative stress as caused by heavy metallic mixture can be inhibited to act on, can be used for
In antipollution skin care item.Therefore the currently preferred plant extracts with significant antipollution effect is camellia flower extract.
The antipollution ingredient added in this skin cream can substantially reduce infant because scorching caused by the factors such as environmental problem
The symptoms such as disease, allergy protect the delicate skin of infant.
In addition, a kind of mild face cream of raw material containing various plants source of the present invention meets country through examining
Professional standard, indices comply fully with sanitary quality standard and the security requirement of national regulation.
Above mentioned skin care compositions can by by required ingredient in suitable container, at ambient conditions
Make its mixing to prepare, any conventional mixing apparatus well known in the art can be used in when preparation, such as: emulsifying homogeneous pot.It is mixed
It is needed when conjunction oily mutually with the difference Hybrid Heating of water phase to 80 DEG C or more, then oil is mutually and homogeneous is mixed in water phase, cools down
Plant extracts is added when to 45 DEG C.
Repeatedly the specific method of acute skin irritation test and result are as follows for irritation test-:
Tested material: tested material is a kind of infant's skin cream of ingredient containing antipollution in this test, without dissolving without dilute
It releases.
Experimental animal and feeding environment:
Used in this test experimental animal be adult, healthy, skin zero damage cavy weight (250~300g),
Female and male, but jenny should be unpregnancy and not farrow.Experimental animal at least with 4, will such as clarify certain
A little suspicious reactions then need to increase experimental animal number.Experimental animal answers single cage to raise, and animal will be in experimental animal room ring before testing
The 3d time is at least adapted in border (laboratory temperature: 20~24 DEG C, relative humidity 60~70%).Experimental animal and experimental animal room
National respective specified should be met.Conventional feed is selected, drinking-water does not limit.
Multiple skin irritation test step:
Experimental animal back backbone two sides coat is cut before 1 test, unhairing range is respectively 3cm × 3cm, application area
2.5cm×2.5cm。
2 take skin cream about 0.5g to be applied on the skin of side, and the other side is not smeared as blank control.It smears 1 time daily,
It is continuous to smear 14d.Since second day, cropping is answered before smearing every time, remains tested material with water or nonirritant solvent cleaning.One
It is observed after hour as a result, scoring by Fig. 1, check plot and trial zone are equally handled.
2. 4.3 evaluation of result: daily every animal average integral is calculated according to the following formula, determines that skin irritatin is strong with Fig. 2
Degree.Test result is shown in Fig. 3.
It can be seen that the skin cream is nontoxic to skin non-stimulated.
Claims (1)
1. a kind of infant's skin cream of ingredient containing antipollution, which is characterized in that include following group grouping by weight percentage
At:
Water/stearoyl dilactic acid sodium/sucrose polyoleate 2%~5%;
Olive oil 0.1%~5%;
Lanolin 0.1%~5%;
Caprylic/capric triglyceride 5%~15%;
Camellia flower extract 0.1%~2%;
Ethylhexyl palmitate, beeswax combination object 4%~8%;
Natrulon H-10 1.0%~5.0%;
Glycerol 10%~20%;
Carbohydrate isomer 0.1%~0.5%;
Ammonium acryloyl taurate/VP copolymer 0.15%~0.3%;
Phenoxyethanol and parahydroxyacet-ophenone 0.1%~1.0%;
Deionized water adds to 100%.
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CN201910539518.5A CN110179710A (en) | 2019-06-20 | 2019-06-20 | A kind of infant's skin cream of the ingredient containing antipollution |
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CN201910539518.5A CN110179710A (en) | 2019-06-20 | 2019-06-20 | A kind of infant's skin cream of the ingredient containing antipollution |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110393691A (en) * | 2019-09-01 | 2019-11-01 | 福建省梦娇兰日用化学品有限公司 | A kind of infant's antiallergic moisturiser containing natural plants |
CN112022785A (en) * | 2020-10-08 | 2020-12-04 | 福建省梦娇兰日用化学品有限公司 | Children moisturizer containing camellia anti-pollution components and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105147529A (en) * | 2015-10-10 | 2015-12-16 | 福建省梦娇兰日用化学品有限公司 | Emollient cream comprising various food production components |
CN106727020A (en) * | 2017-01-10 | 2017-05-31 | 广州小蜜蜂生物科技有限公司 | Baby's moistening skin-care frost |
-
2019
- 2019-06-20 CN CN201910539518.5A patent/CN110179710A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105147529A (en) * | 2015-10-10 | 2015-12-16 | 福建省梦娇兰日用化学品有限公司 | Emollient cream comprising various food production components |
CN106727020A (en) * | 2017-01-10 | 2017-05-31 | 广州小蜜蜂生物科技有限公司 | Baby's moistening skin-care frost |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110393691A (en) * | 2019-09-01 | 2019-11-01 | 福建省梦娇兰日用化学品有限公司 | A kind of infant's antiallergic moisturiser containing natural plants |
CN112022785A (en) * | 2020-10-08 | 2020-12-04 | 福建省梦娇兰日用化学品有限公司 | Children moisturizer containing camellia anti-pollution components and preparation method thereof |
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