CN112543809A - 包含C/EBPα saRNA的组合疗法 - Google Patents

包含C/EBPα saRNA的组合疗法 Download PDF

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Publication number
CN112543809A
CN112543809A CN201980040237.3A CN201980040237A CN112543809A CN 112543809 A CN112543809 A CN 112543809A CN 201980040237 A CN201980040237 A CN 201980040237A CN 112543809 A CN112543809 A CN 112543809A
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sarna
cebpa
active agent
cells
inhibitor
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CN201980040237.3A
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Chinese (zh)
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H·L·莱特福特
V·里比
P·萨特罗姆
D·布莱基
陈忠平
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Mina Therapeutics Ltd
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Mina Therapeutics Ltd
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2320/00—Applications; Uses
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CN201980040237.3A 2018-06-15 2019-06-14 包含C/EBPα saRNA的组合疗法 Pending CN112543809A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862685627P 2018-06-15 2018-06-15
US62/685,627 2018-06-15
US201862731532P 2018-09-14 2018-09-14
US62/731,532 2018-09-14
US201962821533P 2019-03-21 2019-03-21
US62/821,533 2019-03-21
PCT/GB2019/051654 WO2019239144A1 (en) 2018-06-15 2019-06-14 Combination therapies comprising c/ebp alpha sarna

Publications (1)

Publication Number Publication Date
CN112543809A true CN112543809A (zh) 2021-03-23

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CN201980040237.3A Pending CN112543809A (zh) 2018-06-15 2019-06-14 包含C/EBPα saRNA的组合疗法

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US (1) US20210254069A1 (https=)
EP (1) EP3807410A1 (https=)
JP (2) JP2021527651A (https=)
CN (1) CN112543809A (https=)
AU (1) AU2019285344A1 (https=)
CA (1) CA3102334A1 (https=)
WO (1) WO2019239144A1 (https=)

Cited By (2)

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CN114306367A (zh) * 2021-08-27 2022-04-12 赵小洋 一种含有C/EBPα-saRNA的组合物
CN114729366A (zh) * 2019-08-14 2022-07-08 科迪亚克生物科学公司 靶向CEBP/β的细胞外囊泡-ASO构建体

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KR20230009354A (ko) * 2020-05-12 2023-01-17 아스트라제네카 아베 면역 체크포인트 억제제 항체를 사용한 암 치료용 방법 및 조합물
CN111876390B (zh) * 2020-08-12 2021-04-09 湖南南华爱世普林生物技术有限公司 负载化合物的转基因干细胞外泌体在制备药物或美白化妆品中的用途
EP4329777A1 (en) * 2021-04-28 2024-03-06 MiNA Therapeutics Limited Combination therapies comprising c/ebp alpha sarna
WO2024175887A1 (en) * 2023-02-22 2024-08-29 Mina Therapeutics Limited Compositions and methods of using c/ebp alpha sarna

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CN114729366A (zh) * 2019-08-14 2022-07-08 科迪亚克生物科学公司 靶向CEBP/β的细胞外囊泡-ASO构建体
CN114306367A (zh) * 2021-08-27 2022-04-12 赵小洋 一种含有C/EBPα-saRNA的组合物
WO2023024230A1 (zh) * 2021-08-27 2023-03-02 赵小洋 一种含有C/EBPα-saRNA的组合物

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AU2019285344A1 (en) 2020-12-10
WO2019239144A1 (en) 2019-12-19
CA3102334A1 (en) 2019-12-19
EP3807410A1 (en) 2021-04-21
JP2024103632A (ja) 2024-08-01
US20210254069A1 (en) 2021-08-19
JP2021527651A (ja) 2021-10-14

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