CN112543646A - 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 - Google Patents
一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 Download PDFInfo
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- CN112543646A CN112543646A CN201980049882.1A CN201980049882A CN112543646A CN 112543646 A CN112543646 A CN 112543646A CN 201980049882 A CN201980049882 A CN 201980049882A CN 112543646 A CN112543646 A CN 112543646A
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Abstract
本公开提供了一种抗PD‑1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途。该技术方案毒性可控、可耐受，同时联合给药能够有效降低抗PD‑1抗体的不良反应，如反应性毛细血管增生症的发生。
Description
PCT国内申请，说明书已公开。
Claims (17)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311363969.0A CN117298270A (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811313004X | 2018-11-06 | ||
| CN201811313004 | 2018-11-06 | ||
| PCT/CN2019/115608 WO2020093993A1 (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311363969.0A Division CN117298270A (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112543646A true CN112543646A (zh) | 2021-03-23 |
| CN112543646B CN112543646B (zh) | 2023-11-14 |
Family
ID=70611153
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980049882.1A Active CN112543646B (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
| CN202311363969.0A Pending CN117298270A (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311363969.0A Pending CN117298270A (zh) | 2018-11-06 | 2019-11-05 | 一种抗pd-1抗体和法米替尼联合在制备治疗肿瘤的药物中的用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220251203A1 (zh) |
| EP (1) | EP3878468A4 (zh) |
| JP (1) | JP2022512822A (zh) |
| KR (1) | KR20210089168A (zh) |
| CN (2) | CN112543646B (zh) |
| AU (1) | AU2019375808A1 (zh) |
| BR (1) | BR112021007836A2 (zh) |
| CA (1) | CA3117819A1 (zh) |
| MX (1) | MX2021004812A (zh) |
| TW (1) | TWI822897B (zh) |
| WO (1) | WO2020093993A1 (zh) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108601831A (zh) * | 2016-10-10 | 2018-09-28 | 苏州盛迪亚生物医药有限公司 | 一种抗pd-1抗体和vegfr抑制剂联合在制备治疗癌症的药物中的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2008009557A (es) | 2006-01-27 | 2009-01-07 | Shanghai Hengrui Pharm Co Ltd | Inhibidores de la cinasa de proteina de la pirrolo [3,2-c] piridin-4-ona-2-indolinona. |
| EA035037B1 (ru) | 2013-12-12 | 2020-04-21 | Шанхай Хэнжуй Фармасьютикал Ко., Лтд. | Антитело к pd-1, его антигенсвязывающий фрагмент и их медицинское применение |
| CN106999591B (zh) * | 2015-09-28 | 2021-02-23 | 苏州盛迪亚生物医药有限公司 | 一种抗pd-1抗体制剂及其在医药上的应用 |
| CN108079292A (zh) * | 2016-11-23 | 2018-05-29 | 苏州盛迪亚生物医药有限公司 | 一种抗pd-1抗体在制备治疗肝癌的药物中的用途 |
| ES2953595T3 (es) * | 2017-03-01 | 2023-11-14 | Hoffmann La Roche | Procedimientos diagnósticos y terapéuticos para el cáncer |
| CN109893654B (zh) * | 2017-12-11 | 2021-07-27 | 江苏恒瑞医药股份有限公司 | Vegfr抑制剂治疗肿瘤的方法 |
-
2019
- 2019-11-05 EP EP19881012.9A patent/EP3878468A4/en active Pending
- 2019-11-05 WO PCT/CN2019/115608 patent/WO2020093993A1/zh active Application Filing
- 2019-11-05 KR KR1020217014341A patent/KR20210089168A/ko active Search and Examination
- 2019-11-05 MX MX2021004812A patent/MX2021004812A/es unknown
- 2019-11-05 CA CA3117819A patent/CA3117819A1/en active Pending
- 2019-11-05 JP JP2021522987A patent/JP2022512822A/ja active Pending
- 2019-11-05 BR BR112021007836-3A patent/BR112021007836A2/pt unknown
- 2019-11-05 AU AU2019375808A patent/AU2019375808A1/en active Pending
- 2019-11-05 CN CN201980049882.1A patent/CN112543646B/zh active Active
- 2019-11-05 US US17/288,894 patent/US20220251203A1/en active Pending
- 2019-11-05 CN CN202311363969.0A patent/CN117298270A/zh active Pending
- 2019-11-05 TW TW108140100A patent/TWI822897B/zh active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108601831A (zh) * | 2016-10-10 | 2018-09-28 | 苏州盛迪亚生物医药有限公司 | 一种抗pd-1抗体和vegfr抑制剂联合在制备治疗癌症的药物中的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20220251203A1 (en) | 2022-08-11 |
| TWI822897B (zh) | 2023-11-21 |
| CN117298270A (zh) | 2023-12-29 |
| CA3117819A1 (en) | 2020-05-14 |
| BR112021007836A2 (pt) | 2021-08-10 |
| JP2022512822A (ja) | 2022-02-07 |
| AU2019375808A1 (en) | 2021-06-17 |
| EP3878468A1 (en) | 2021-09-15 |
| EP3878468A4 (en) | 2022-08-24 |
| KR20210089168A (ko) | 2021-07-15 |
| WO2020093993A1 (zh) | 2020-05-14 |
| MX2021004812A (es) | 2021-06-08 |
| CN112543646B (zh) | 2023-11-14 |
| TW202039001A (zh) | 2020-11-01 |
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