CN112512553A - 新的肌肉因子及其用途 - Google Patents

新的肌肉因子及其用途 Download PDF

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Publication number
CN112512553A
CN112512553A CN201980049908.2A CN201980049908A CN112512553A CN 112512553 A CN112512553 A CN 112512553A CN 201980049908 A CN201980049908 A CN 201980049908A CN 112512553 A CN112512553 A CN 112512553A
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CN
China
Prior art keywords
polypeptide
seq
muscle
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980049908.2A
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English (en)
Chinese (zh)
Inventor
H·霍夫灵
H·凯勒
S·勒米尔
S·萨默马特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
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Novartis AG
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Application filed by Novartis AG filed Critical Novartis AG
Publication of CN112512553A publication Critical patent/CN112512553A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725Proteoglycans, e.g. aggreccan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201980049908.2A 2018-08-02 2019-07-31 新的肌肉因子及其用途 Pending CN112512553A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18187131.0 2018-08-02
EP18187131 2018-08-02
PCT/IB2019/056537 WO2020026167A1 (en) 2018-08-02 2019-07-31 New myokines and uses thereof

Publications (1)

Publication Number Publication Date
CN112512553A true CN112512553A (zh) 2021-03-16

Family

ID=63144838

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980049908.2A Pending CN112512553A (zh) 2018-08-02 2019-07-31 新的肌肉因子及其用途

Country Status (10)

Country Link
US (1) US20220144908A1 (https=)
EP (1) EP3829620B1 (https=)
JP (1) JP2021533113A (https=)
KR (1) KR20210041580A (https=)
CN (1) CN112512553A (https=)
AU (1) AU2019313506A1 (https=)
CA (1) CA3106518A1 (https=)
IL (1) IL280369A (https=)
TW (1) TW202019457A (https=)
WO (1) WO2020026167A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113424794A (zh) * 2021-04-16 2021-09-24 安徽农业大学 一种优质抗病型地方鸡新品系选育方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004532A2 (en) * 2001-07-05 2003-01-16 Geneprot, Inc. Q9ul33/q9nzz4 and q9h5p3 splice variants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001522239A (ja) 1997-03-21 2001-11-13 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド 87個のヒト分泌タンパク質
JP2003502004A (ja) 1997-10-02 2003-01-21 ジェネティックス・インスチチュート・インコーポレーテッド 分泌蛋白およびそれらをコードするポリヌクレオチド
CA2311201A1 (en) 1999-08-05 2001-02-05 Genset S.A. Ests and encoded human proteins
JP2004313167A (ja) * 2003-02-24 2004-11-11 Joji Inasawa 薬剤耐性マーカーおよびその利用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004532A2 (en) * 2001-07-05 2003-01-16 Geneprot, Inc. Q9ul33/q9nzz4 and q9h5p3 splice variants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HONGYANG XIE等: "Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury", J CELL MOL MED., vol. 22, no. 10 *
NCBI REFERENCE SEQUENCE: "NP_001287969.1,uncharacterized protein C1orf54 isoform b precursor [Homo sapiens]", GENBANK *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113424794A (zh) * 2021-04-16 2021-09-24 安徽农业大学 一种优质抗病型地方鸡新品系选育方法及应用

Also Published As

Publication number Publication date
US20220144908A1 (en) 2022-05-12
AU2019313506A1 (en) 2021-01-14
JP2021533113A (ja) 2021-12-02
CA3106518A1 (en) 2020-02-06
IL280369A (en) 2021-03-01
TW202019457A (zh) 2020-06-01
KR20210041580A (ko) 2021-04-15
EP3829620A1 (en) 2021-06-09
WO2020026167A1 (en) 2020-02-06
EP3829620B1 (en) 2024-05-29

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Application publication date: 20210316