CN112512513A - 用于延缓活性物质在远端结肠中释放的具有多层结构的丸剂 - Google Patents
用于延缓活性物质在远端结肠中释放的具有多层结构的丸剂 Download PDFInfo
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- CN112512513A CN112512513A CN201980049484.XA CN201980049484A CN112512513A CN 112512513 A CN112512513 A CN 112512513A CN 201980049484 A CN201980049484 A CN 201980049484A CN 112512513 A CN112512513 A CN 112512513A
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- active substance
- budesonide
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18190638.9 | 2018-08-24 | ||
| EP18190638.9A EP3613414A1 (de) | 2018-08-24 | 2018-08-24 | Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon |
| PCT/EP2019/072429 WO2020039017A1 (de) | 2018-08-24 | 2019-08-22 | Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112512513A true CN112512513A (zh) | 2021-03-16 |
Family
ID=63405023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980049484.XA Pending CN112512513A (zh) | 2018-08-24 | 2019-08-22 | 用于延缓活性物质在远端结肠中释放的具有多层结构的丸剂 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11173121B2 (hr) |
| EP (2) | EP3613414A1 (hr) |
| JP (1) | JP7374992B2 (hr) |
| CN (1) | CN112512513A (hr) |
| AU (1) | AU2019326752A1 (hr) |
| CA (1) | CA3108257A1 (hr) |
| DK (1) | DK3840734T3 (hr) |
| EA (1) | EA202190565A1 (hr) |
| ES (1) | ES2927000T3 (hr) |
| HR (1) | HRP20221162T1 (hr) |
| HU (1) | HUE060169T2 (hr) |
| IL (1) | IL279825B2 (hr) |
| LT (1) | LT3840734T (hr) |
| PL (1) | PL3840734T3 (hr) |
| PT (1) | PT3840734T (hr) |
| RS (1) | RS63628B1 (hr) |
| SI (1) | SI3840734T1 (hr) |
| UA (1) | UA127521C2 (hr) |
| WO (1) | WO2020039017A1 (hr) |
| ZA (1) | ZA202100512B (hr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4382099A1 (en) | 2022-12-05 | 2024-06-12 | ADD Advanced Drug Delivery Technologies, Ltd. | Drug loaded modified release pellets |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5932249A (en) * | 1993-09-23 | 1999-08-03 | Dr. Falk Pharma Gmbh | Budesonide pellets with a controlled released pattern and process for producing the same |
| US20050089571A1 (en) * | 2002-03-27 | 2005-04-28 | Roehm Gmbh & Co.Kg | Pharmaceutical formulation for the active ingredient budesonide |
| EP1607087A1 (en) * | 2003-03-27 | 2005-12-21 | Hisamitsu Pharmaceutical Co., Inc. | Medicinal oral preparations for colon delivery, medicinal oral preparations for treating colon cancer and medicinal oral preparations for treating colitis |
| CN101108171A (zh) * | 2006-07-17 | 2008-01-23 | 复旦大学 | 一种布地奈德肠溶缓释微丸及其制备方法 |
| CN101677958A (zh) * | 2007-03-26 | 2010-03-24 | 帝国制药株式会社 | 用于结肠-特异性递送的口服药物制剂 |
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| SE8903914D0 (sv) | 1989-11-22 | 1989-11-22 | Draco Ab | Oral composition for the treatment of inflammatory bowel diseases |
| US5643602A (en) * | 1989-11-22 | 1997-07-01 | Astra Aktiebolag | Oral composition for the treatment of inflammatory bowel disease |
| DE4340057A1 (de) * | 1993-11-24 | 1995-06-01 | Falk Pharma Gmbh | Budesonid-Arzneimittel zur Verbesserung der enteralen Flüssigkeitsresorption, insbesondere nach postoperativen Zuständen |
| PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
| JP2004507487A (ja) | 2000-08-29 | 2004-03-11 | メファ・アクチェンゲゼルシャフト | 腸疾患治療薬 |
| MXPA04004747A (es) | 2001-11-23 | 2004-08-02 | Procter & Gamble | Forma de dosificacion farmaceutica con multiples recubrimientos. |
| DE10250543A1 (de) * | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| DE602004028497D1 (de) * | 2003-09-15 | 2010-09-16 | Nycomed Gmbh | Verwendung von ciclesonid zur behandlung von entzündlichen darmerkrankungen |
| GB0808537D0 (en) | 2008-05-12 | 2008-06-18 | Archimedes Dev Ltd | Compositions |
| CN103705481B (zh) | 2013-11-15 | 2017-10-20 | 中国药科大学 | 一种萘普生结肠定位释药微丸及其制备方法 |
| EP3346996A4 (en) * | 2015-09-11 | 2019-04-17 | Sun Pharmaceutical Industries Limited | ORAL PHARMACEUTICAL PHARMACEUTICAL FORM OF BUDESONID |
| EP3257501A1 (en) | 2016-06-14 | 2017-12-20 | Tillotts Pharma AG | Multiple unit dosage form comprising a core with individual core units covered by a mucoadhesive material, and an enteric core coating |
-
2018
- 2018-08-24 EP EP18190638.9A patent/EP3613414A1/de not_active Withdrawn
-
2019
- 2019-08-22 ES ES19765417T patent/ES2927000T3/es active Active
- 2019-08-22 PL PL19765417.1T patent/PL3840734T3/pl unknown
- 2019-08-22 EP EP19765417.1A patent/EP3840734B1/de active Active
- 2019-08-22 RS RS20220919A patent/RS63628B1/sr unknown
- 2019-08-22 SI SI201930318T patent/SI3840734T1/sl unknown
- 2019-08-22 LT LTEPPCT/EP2019/072429T patent/LT3840734T/lt unknown
- 2019-08-22 PT PT197654171T patent/PT3840734T/pt unknown
- 2019-08-22 IL IL279825A patent/IL279825B2/en unknown
- 2019-08-22 UA UAA202101343A patent/UA127521C2/uk unknown
- 2019-08-22 WO PCT/EP2019/072429 patent/WO2020039017A1/de active Search and Examination
- 2019-08-22 JP JP2021510044A patent/JP7374992B2/ja active Active
- 2019-08-22 CA CA3108257A patent/CA3108257A1/en active Pending
- 2019-08-22 EA EA202190565A patent/EA202190565A1/ru unknown
- 2019-08-22 HR HRP20221162TT patent/HRP20221162T1/hr unknown
- 2019-08-22 CN CN201980049484.XA patent/CN112512513A/zh active Pending
- 2019-08-22 AU AU2019326752A patent/AU2019326752A1/en active Pending
- 2019-08-22 HU HUE19765417A patent/HUE060169T2/hu unknown
- 2019-08-22 DK DK19765417.1T patent/DK3840734T3/da active
- 2019-08-22 US US17/263,710 patent/US11173121B2/en active Active
-
2021
- 2021-01-25 ZA ZA2021/00512A patent/ZA202100512B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5932249A (en) * | 1993-09-23 | 1999-08-03 | Dr. Falk Pharma Gmbh | Budesonide pellets with a controlled released pattern and process for producing the same |
| US20050089571A1 (en) * | 2002-03-27 | 2005-04-28 | Roehm Gmbh & Co.Kg | Pharmaceutical formulation for the active ingredient budesonide |
| EP1607087A1 (en) * | 2003-03-27 | 2005-12-21 | Hisamitsu Pharmaceutical Co., Inc. | Medicinal oral preparations for colon delivery, medicinal oral preparations for treating colon cancer and medicinal oral preparations for treating colitis |
| CN101108171A (zh) * | 2006-07-17 | 2008-01-23 | 复旦大学 | 一种布地奈德肠溶缓释微丸及其制备方法 |
| CN101677958A (zh) * | 2007-03-26 | 2010-03-24 | 帝国制药株式会社 | 用于结肠-特异性递送的口服药物制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| UA127521C2 (uk) | 2023-09-20 |
| US20210228487A1 (en) | 2021-07-29 |
| CA3108257A1 (en) | 2020-02-27 |
| LT3840734T (lt) | 2022-10-25 |
| EP3613414A1 (de) | 2020-02-26 |
| AU2019326752A1 (en) | 2021-01-28 |
| EA202190565A1 (ru) | 2021-06-01 |
| IL279825B2 (en) | 2024-04-01 |
| JP7374992B2 (ja) | 2023-11-07 |
| HRP20221162T1 (hr) | 2022-11-25 |
| DK3840734T3 (da) | 2022-09-26 |
| PT3840734T (pt) | 2022-09-19 |
| JP2022503581A (ja) | 2022-01-12 |
| EP3840734A1 (de) | 2021-06-30 |
| PL3840734T3 (pl) | 2022-12-19 |
| ES2927000T3 (es) | 2022-10-31 |
| ZA202100512B (en) | 2022-02-23 |
| SI3840734T1 (sl) | 2022-10-28 |
| RS63628B1 (sr) | 2022-10-31 |
| EP3840734B1 (de) | 2022-07-20 |
| IL279825A (en) | 2021-03-01 |
| US11173121B2 (en) | 2021-11-16 |
| WO2020039017A1 (de) | 2020-02-27 |
| IL279825B1 (en) | 2023-12-01 |
| HUE060169T2 (hu) | 2023-02-28 |
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