CN112494600A - A Chinese medicinal composition for delaying cell and blood vessel aging - Google Patents

A Chinese medicinal composition for delaying cell and blood vessel aging Download PDF

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CN112494600A
CN112494600A CN202011396854.8A CN202011396854A CN112494600A CN 112494600 A CN112494600 A CN 112494600A CN 202011396854 A CN202011396854 A CN 202011396854A CN 112494600 A CN112494600 A CN 112494600A
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aging
delaying cell
chinese medicine
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冉明
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Abstract

The invention discloses a traditional Chinese medicine composition for delaying cell and blood vessel aging, which comprises American ginseng, astragalus, rhizoma polygonati, red sage, rhizoma alismatis, cassia seed, medlar, lucid ganoderma, tuber fleeceflower root, raw Chinese yam, desertliving cistanche, Chinese magnoliavine fruit, dodder, eucommia bark, achyranthes, root of rehmannia, dogwood, poria with hostwood, morinda officinalis, red halloysite and pseudo-ginseng. The invention provides a traditional Chinese medicine composition for delaying cell and blood vessel aging, which is prepared by compounding a plurality of natural components, is safe and reliable and has no side effect; has strong anti-free radical and anti-oxidation effects, can reduce the aging speed of cells, enhance metabolism, improve immunity and further effectively delay aging; the Chinese medicinal composition also has the effects of reducing blood lipid, preventing fatty liver, and softening blood vessel, thereby reducing occurrence of cardiovascular disease and cerebrovascular disease; in clinical tests, the traditional Chinese medicine composition has the effect of treating and improving symptoms such as low immunity, hypertension, fatigue, weakness, listlessness and the like, and the effective rate is over 95 percent.

Description

A Chinese medicinal composition for delaying cell and blood vessel aging
Technical Field
The invention relates to the technical field of anti-aging health care products, in particular to a traditional Chinese medicine composition for delaying cell and blood vessel aging.
Background
Aging is a spontaneous inevitable process of an organism over time, and is the result of long-term interaction of the organism with the external environment. With age, human body functions begin to decline, manifested by structural and functional decline, and decline in fitness and resistance.
Under the double pressure of working and living, young people excessively consume and transudate physical energy, so that tissues and organs are aged in advance. According to statistics, the incidence of diseases such as coronary heart disease, hypertension, hyperlipidemia and diabetes also tends to be younger as the number of middle-aged people suffering from cardiovascular and cerebrovascular diseases such as myocardial infarction and cerebral hemorrhage increases greatly in recent years. With the improvement of living standard of people, people continuously seek methods for prolonging life, improving immunity, overcoming various diseases and improving body functions so as to improve life quality, so that health care products with anti-aging function are continuously required to be developed.
Disclosure of Invention
Based on the technical problems in the background art, the invention provides a traditional Chinese medicine composition for delaying cell and blood vessel senescence, which is prepared by compounding a plurality of traditional Chinese medicine components, has no natural side effect, and has the function of delaying senescence.
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25-35 parts of American ginseng, 7-15 parts of astragalus membranaceus, 10-18 parts of rhizoma polygonati, 2-9 parts of red paeony root, 2-9 parts of rhizoma alismatis, 2-10 parts of semen cassiae, 20-30 parts of fructus lycii, 10-18 parts of lucid ganoderma, 15-23 parts of polygonum multiflorum, 10-15 parts of raw Chinese yam, 20-30 parts of cistanches, 15-25 parts of schisandra chinensis, 15-25 parts of semen cuscutae, 15-25 parts of eucommia ulmoides, 2-10 parts of radix achyranthis bidentatae, 2-10 parts of radix rehmanniae, 2-10 parts of dogwood and 2-10 parts of poria with hostwood.
Preferably, 2-10 parts of morinda officinalis is also included.
Preferably, the red halloysite also comprises 2-10 parts.
Preferably, the traditional Chinese medicine also comprises 15-25 parts of pseudo-ginseng.
Preferably, the traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 9 parts of astragalus, 12 parts of rhizoma polygonati, 6 parts of red peony root, 6 parts of rhizoma alismatis, 4 parts of semen cassiae, 24 parts of wolfberry fruit, 12 parts of lucid ganoderma, 18 parts of polygonum multiflorum, 12 parts of raw yam, 24 parts of cistanches, 20 parts of schisandra chinensis, 18 parts of semen cuscutae, 18 parts of eucommia bark, 6 parts of achyranthes bidentata, 6 parts of radix rehmanniae, 6 parts of dogwood, 6 parts of poria with hostwood, 6 parts of morinda officinalis, 6 parts of red halloysite and 18 parts of pseudo-ginseng.
A preparation method of a traditional Chinese medicine composition for delaying cell and blood vessel aging comprises the following steps: s1: mixing, cleaning and drying various components; s2: drying and crushing the components, and sieving the crushed components with a 120-mesh sieve; s3: sterilizing, and making into tablet.
Further, the tablet weighs 0.5g per tablet.
The traditional Chinese medicine composition prepared by the invention is used for delaying cell and blood vessel aging, and has the functions of treating and improving symptoms such as hypoimmunity, hypertension, fatigue, weakness, listlessness and the like.
The main components in the invention have the following functions:
the astragalus extract contains numerous chemical components, and mainly contains saponin, flavone, polysaccharide, amino acid and other components; the astragalus can promote the synthesis of RNA and protein and enhance the physiological metabolism of cells, thereby prolonging the service life of the cells and delaying aging; in addition, radix astragali can expand coronary artery, improve myocardial blood supply, and enhance immunity.
Rhizoma Polygonati is sweet and neutral, and has effects of enhancing immunity, promoting metabolism, lowering blood pressure, reducing blood sugar, reducing blood lipid, preventing atherosclerosis, delaying aging, and resisting bacteria.
The red herbs are sour and bitter in taste and slightly cold in nature; it enters liver, heart and spleen meridians; enter blood system, astringe and descend to disperse slightly. Has effects of clearing heat, cooling blood, stopping bleeding, promoting blood circulation, removing blood stasis and relieving pain.
Alisma orientale, sweet in nature, bland in flavor and cold in nature, enters kidney and bladder meridians. Modern medicine shows that the alisma contains triterpenes and has the functions of reducing blood fat and protecting heart and cerebral vessels.
Semen Cassiae has effects of removing liver fire, improving eyesight, reducing blood lipid, lowering blood pressure, and softening blood vessel.
The ginseng contains various saponins and polysaccharides, and the leachate can be slowly absorbed by skin without adverse stimulation, and has effects of promoting skin blood circulation, resisting oxidation, resisting aging, relieving fatigue, protecting liver, regulating cardiovascular function, and exciting hematopoietic system function.
The functional component in the medlar is medlar polysaccharide which has main selection function in human body and thymic T cells, can capture the increased number of mature cells, and enhance the emptying function, so that the thymic cells are transferred to the periphery to be increased, and the retrogression of the aged thymus can be reversed; can also enhance bone marrow hemopoiesis function, so fructus Lycii has antiaging effect.
Ganoderma contains abundant polysaccharides and triterpenes, and can scavenge free radicals and repair damaged cells; ganoderma has effects in protecting liver, removing toxic substances, promoting liver cell regeneration, and regulating immunity; can be used for preventing and treating hyperlipidemia, chronic bronchitis, neurosis and brain function deterioration of the middle aged and the elderly people.
The polygonum multiflorum can promote the growth of nerve cells, has an auxiliary treatment effect on neurasthenia and other nervous system diseases, can regulate serum cholesterol, reduce blood sugar, and improve the capacity of converting hepatic cells and metabolizing cholesterol, and also has a good antioxidation effect.
The fresh yam is mild in property and sweet in taste, and has the effects of tonifying spleen and nourishing stomach, promoting the production of body fluid and benefiting lung, and tonifying kidney and arresting seminal emission.
The cistanche deserticola polysaccharide has obvious influence on the formation and activity of human lymphocytes, and can increase the proliferation reaction of the lymphocytes so as to enhance the immunologic function of an organism; the benzyl alcohol sugar contained in the cistanche salsa is the most effective component for delaying aging, and has obvious effect of delaying the aging of hypophysis, gonad, thymus and other parts of a human body.
Fructus Schisandrae contains abundant organic acids, vitamins, flavonoids, phytosterols and lignans, and can enhance body defense ability to nonspecific stimulation; increasing cell immunity, and improving SOD activity of brain, liver and spleen, and has effects of improving immunity, resisting oxidation and resisting aging.
The polysaccharide in semen Cuscutae has effects of scavenging oxygen free radicals and resisting lipid peroxidation to resist aging; the dodder can also enhance the phagocytic function of abdominal cavity macrophages, promote the proliferation reaction of spleen lymphocytes, induce the generation of interleukin and the like by increasing the wet weight of thymus and spleen immune organs, and effectively enhance the immunity of organisms.
The Eucommiae cortex is rich in Eucommiae cortex gelatin, pinoresinol diglucoside, kaempferol, Eucommiae cortex glycoside, Ajuga glycoside and various microelements, and has effects of enhancing cell SOD activity, delaying aging, and dilating blood vessel.
The ecdysterone contained in Achyranthis radix has strong protein synthesis promoting effect, and also has effects of regulating blood sugar and blood lipid, promoting collagen protein synthesis, resisting arrhythmia, relieving fatigue, regulating blood sugar, promoting cell growth, stimulating dermal cell division, delaying aging and improving immunity.
The rehmannia root and the rehmannia root are cool in nature and sweet in taste, enter heart, liver and kidney channels, cool blood and nourish yin, and have the effects of clearing heat, nourishing yin, cooling blood, stopping bleeding, promoting the production of body fluid and quenching thirst. Modern pharmacological research shows that rehmannia has the functions of resisting radiation, protecting liver, lowering blood sugar, strengthening heart, stopping bleeding, promoting urination and resisting fungi.
Corni fructus has effects of invigorating liver and kidney, astringing, arresting discharge, arresting seminal emission, reducing urination, stopping leukorrhagia, stopping sweating, lowering blood sugar and resisting bacteria.
Fu Shen is sweet and light in flavor, mild and warm in nature, enters heart meridian, and can nourish heart and induce tranquilization.
Radix Morindae officinalis contains physcion, methyl isoalizarin, anthrone, beta-sitosterol, palmitic acid, monothiocyanato, tetraacethylasperuloside, etc., and has effects of relieving fatigue, improving immunity, and lowering blood pressure.
Halloysitum rubrum is warm in nature, sweet, sour and astringent in taste; entering large intestine meridian and stomach meridian; the red halloysite can obviously inhibit ADP-induced platelet aggregation.
The notoginseng contains various effective components such as saponin, sanchinin, notoginseng polysaccharide, amino acid and the like, can strengthen and improve coronary microcirculation and dilate blood vessels, has the effects of treating and protecting health for diseases of a blood system, a cardiovascular system, a cerebrovascular system, a central nervous system and the like, and also has the effects of resisting aging and oxidation.
The usage method comprises the following steps: the composition can be taken twice a day, 4-6g once with warm water, and can be taken for a long time.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a traditional Chinese medicine composition for delaying cell and blood vessel aging, which is prepared by compounding a plurality of natural components, is safe and reliable and has no side effect; the Chinese medicinal composition contains various functional components such as plant polysaccharide, saponin, flavone, etc., has strong free radical resisting and antioxidant effects, and can reduce aging rate of cells, enhance metabolism, improve immunity, and further effectively delay aging; the Chinese medicinal composition also has the effects of reducing blood lipid, preventing fatty liver, and softening blood vessel, thereby reducing occurrence of cardiovascular disease and cerebrovascular disease; in clinical tests, the traditional Chinese medicine composition has the effect of treating and improving symptoms such as low immunity, hypertension, fatigue, weakness, listlessness and the like, and the effective rate is more than 94%.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples.
Example 1
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 7 parts of astragalus, 10 parts of rhizoma polygonati, 2 parts of red peony root, 2 parts of rhizoma alismatis, 2 parts of semen cassiae, 30 parts of wolfberry fruit, 18 parts of lucid ganoderma, 15 parts of polygonum multiflorum, 10 parts of raw yam, 20 parts of cistanches, 25 parts of schisandra chinensis, 25 parts of semen cuscutae, 15 parts of eucommia bark, 2 parts of achyranthes bidentata, 2 parts of radix rehmanniae, 2 parts of dogwood, 10 parts of poria with hostwood, 10 parts of morinda officinalis, 10 parts of red halloysite and 15 parts of pseudo-ginseng.
A preparation method of a traditional Chinese medicine composition for delaying cell and blood vessel aging comprises the following steps: s1: mixing, cleaning and drying various components; s2: drying and crushing the components, and sieving the crushed components with a 120-mesh sieve; s3: sterilizing, and making into tablet with weight of 0.5 g.
Example 2
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 15 parts of astragalus, 18 parts of rhizoma polygonati, 9 parts of red peony root, 9 parts of rhizoma alismatis, 10 parts of semen cassiae, 20 parts of wolfberry fruit, 10 parts of lucid ganoderma, 23 parts of polygonum multiflorum, 15 parts of raw Chinese yam, 30 parts of cistanches, 15 parts of schisandra chinensis, 15 parts of semen cuscutae, 25 parts of eucommia bark, 10 parts of achyranthes bidentata, 10 parts of radix rehmanniae, 10 parts of dogwood, 2 parts of poria with hostwood, 2 parts of morinda officinalis, 2 parts of red halloysite and 25 parts of pseudo-ginseng.
The preparation method is as in example 1.
Example 3
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 9 parts of astragalus, 12 parts of rhizoma polygonati, 6 parts of red peony root, 6 parts of rhizoma alismatis, 4 parts of semen cassiae, 24 parts of wolfberry fruit, 12 parts of lucid ganoderma, 18 parts of polygonum multiflorum, 12 parts of raw yam, 24 parts of cistanches, 20 parts of schisandra chinensis, 18 parts of semen cuscutae, 18 parts of eucommia bark, 6 parts of achyranthes bidentata, 6 parts of radix rehmanniae, 6 parts of dogwood, 6 parts of poria with hostwood, 6 parts of morinda officinalis, 6 parts of red halloysite and 18 parts of pseudo-ginseng.
The preparation method is as in example 1.
Example 4
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 10 parts of astragalus, 17 parts of rhizoma polygonati, 3 parts of red sage, 8 parts of rhizoma alismatis, 6 parts of semen cassiae, 29 parts of wolfberry, 15 parts of lucid ganoderma, 22 parts of polygonum multiflorum, 11 parts of raw Chinese yam, 22 parts of cistanches, 17 parts of schisandra chinensis, 21 parts of semen cuscutae, 19 parts of eucommia ulmoides, 5 parts of achyranthes bidentata, 9 parts of radix rehmanniae, 3 parts of dogwood, 8 parts of poria with hostwood, 7 parts of morinda officinalis, 5 parts of red halloysite and 20 parts of pseudo-ginseng.
The preparation method is as in example 1.
Example 5
A traditional Chinese medicine composition for delaying cell and vascular aging comprises the following components in parts by weight: 25 parts of American ginseng, 13 parts of astragalus, 15 parts of rhizoma polygonati, 7 parts of red peony root, 5 parts of rhizoma alismatis, 9 parts of semen cassiae, 26 parts of wolfberry fruit, 17 parts of lucid ganoderma, 20 parts of polygonum multiflorum, 13 parts of raw Chinese yam, 26 parts of cistanches, 23 parts of schisandra chinensis, 20 parts of semen cuscutae, 24 parts of eucommia bark, 8 parts of achyranthes bidentata, 4 parts of radix rehmanniae, 7 parts of dogwood, 3 parts of poria with hostwood, 4 parts of morinda officinalis, 9 parts of red halloysite and 23 parts of pseudo-ginseng.
The preparation method is as in example 1.
Test of
Acute oral toxicity test of mice
The experimental scheme is as follows: selecting healthy and mature ICR mice with the weight of 20-25g, and 10 male and female mice respectively; after the mice were fasted for 12 hours without water deprivation, the mice were gavaged for 3 times at 20g/kgBW within 1 day, and 1 time every 8 hours. Animals had free access to food and water 2 hours after gavage, and the animals were recorded for 7 days of continuous observation for the signs of intoxication and death.
Experimental drugs: the Chinese medicinal composition prepared in example 3.
The experimental results are as follows: see table 1. During the experiment, no obvious toxic manifestation nor death was seen in each mouse.
TABLE 1 results of acute toxicity test in mice
Figure BSA0000226746490000061
Second, clinical trial
1. Clinical test of immunity
Trial objects: the 60 test subjects, age 30-65, had the main symptoms of low immunity, easy fatigue, and easy cold with slight weather changes, and the average cold is once a month.
The using method comprises the following steps: after the traditional Chinese medicine composition prepared in the example 1 is taken 2 times a day and 4g each time and continuously used for 2 months, the effect of the test is visited.
And (4) judging the standard: the effect is shown: the number of cold is obviously reduced, and the energy is abundant; the method has the following advantages: the improvement is achieved to a certain extent before use; and (4) invalidation: no change in symptoms.
And (4) trial results: of 60 users, 17 effective persons, 41 effective persons and 2 ineffective persons are effective, and the total effective rate is 96.7%.
2. Clinical test for cell activity and vascular elasticity
Trial objects: 50 female testers aged 30-55 years had the symptoms of insomnia, hypomnesis, rough and dark skin, inelasticity, deepened wrinkles and large pores.
The using method comprises the following steps: the traditional Chinese medicine composition prepared in the example 2 is taken 2 times a day, 5g is taken each time, and after the traditional Chinese medicine composition is continuously used for 1 month, the effect of the test is realized.
And (4) judging the standard: the effect is shown: the skin is ruddy and glossy, the memory is improved, and insomnia symptoms are few; the method has the following advantages: the improvement is achieved to a certain extent before use; and (4) invalidation: no change in symptoms.
And (4) trial results: of the 50 users, 12 effective persons, 35 effective persons and 3 ineffective persons are effective, and the total effective rate is 94%.
3. Clinical trial for lowering blood pressure
Trial objects: 90 hypertension patients, age 45-70 years, with a course of disease of over 2 years.
The using method comprises the following steps: after the traditional Chinese medicine composition prepared in the example 4 is taken 2 times a day, 5g of the composition is taken each time, and the effect is tried after the composition is continuously used for 5 months.
And (4) judging the standard: the effect is shown: after stopping the medicine, the blood pressure is obviously controlled; the method has the following advantages: after stopping taking the medicine, the blood pressure rises slightly; and (4) invalidation: no change in symptoms.
And (4) trial results: among 90 users, 13 effective users, 72 effective users and 5 ineffective users have a total effective rate of 94.4 percent.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (8)

1. A traditional Chinese medicine composition for delaying cell and vascular aging is characterized by comprising the following components in parts by weight: 25-35 parts of American ginseng, 7-15 parts of astragalus membranaceus, 10-18 parts of rhizoma polygonati, 2-9 parts of red paeony root, 2-9 parts of rhizoma alismatis, 2-10 parts of semen cassiae, 20-30 parts of fructus lycii, 10-18 parts of lucid ganoderma, 15-23 parts of polygonum multiflorum, 10-15 parts of raw Chinese yam, 20-30 parts of cistanches, 15-25 parts of schisandra chinensis, 15-25 parts of semen cuscutae, 15-25 parts of eucommia ulmoides, 2-10 parts of radix achyranthis bidentatae, 2-10 parts of radix rehmanniae, 2-10 parts of dogwood and 2-10 parts of poria with hostwood.
2. The Chinese medicinal composition for delaying cell and vascular aging of claim 1, further comprising 2-10 parts of morinda officinalis how.
3. The Chinese medicinal composition for delaying cell and vascular aging of claim 1, further comprising 2-10 parts of red halloysite.
4. The traditional Chinese medicine composition for delaying cell and vascular aging of claim 1, further comprising 15-25 parts of pseudo-ginseng.
5. The traditional Chinese medicine composition for delaying cell and vascular aging according to claim 1, which is characterized by comprising the following components in parts by weight: 25 parts of American ginseng, 9 parts of astragalus mongholicus, 12 parts of rhizoma polygonati, 6 parts of red peony root, 6 parts of rhizoma alismatis, 4 parts of semen cassiae, 24 parts of wolfberry fruit, 12 parts of lucid ganoderma, 18 parts of polygonum multiflorum, 12 parts of raw Chinese yam, 24 parts of cistanches, 20 parts of schisandra chinensis, 18 parts of semen cuscutae, 18 parts of eucommia ulmoides, 6 parts of radix achyranthis bidentatae, 6 parts of radix rehmanniae, 6 parts of dogwood, 6 parts of poria with hostwood, 6 parts of morinda officinalis, 6 parts of red halloysite and 18 parts.
6. The preparation method of the traditional Chinese medicine composition for delaying cell and vascular aging according to any one of claims 1 to 5, which is characterized by comprising the following steps: s1: mixing, cleaning and drying various components; s2: drying and crushing the components, and sieving the crushed components with a 120-mesh sieve; s3: sterilizing, and making into tablet.
7. The method for preparing a Chinese medicinal composition for delaying cell and vascular aging of claim 6, wherein the tablet is 0.5 g.
8. The Chinese medicinal composition according to any one of claims 1-5, 7 is used for delaying cellular and vascular aging, and treating and improving symptoms such as hypoimmunity, hypertension, fatigue, weakness, listlessness, etc.
CN202011396854.8A 2020-12-02 2020-12-02 A Chinese medicinal composition for delaying cell and blood vessel aging Withdrawn CN112494600A (en)

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