CN112480494A - Self-antibacterial medical gloves and preparation method thereof - Google Patents
Self-antibacterial medical gloves and preparation method thereof Download PDFInfo
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- CN112480494A CN112480494A CN202011279123.5A CN202011279123A CN112480494A CN 112480494 A CN112480494 A CN 112480494A CN 202011279123 A CN202011279123 A CN 202011279123A CN 112480494 A CN112480494 A CN 112480494A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L7/00—Compositions of natural rubber
- C08L7/02—Latex
-
- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D19/00—Gloves
- A41D19/0055—Plastic or rubber gloves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B42/00—Surgical gloves; Finger-stalls specially adapted for surgery; Devices for handling or treatment thereof
- A61B42/10—Surgical gloves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/003—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
- B29C41/14—Dipping a core
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/0427—Coating with only one layer of a composition containing a polymer binder
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2307/00—Characterised by the use of natural rubber
- C08J2307/02—Latex
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2475/00—Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
- C08J2475/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2489/00—Characterised by the use of proteins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2296—Oxides; Hydroxides of metals of zinc
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Textile Engineering (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Gloves (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
The invention discloses a self-antibacterial medical glove and a preparation method thereof. The preparation method comprises the following steps: preparing nano antibacterial vulcanized latex by adopting natural latex and inorganic nano antibacterial compound dispersion liquid; soaking a coagulant after washing the mold and drying; dipping the nano antibacterial vulcanized latex, shaping and drying to prepare the self-antibacterial medical glove. The self-antibacterial medical gloves prepared by the invention have antibacterial performance, have compact structures and higher mechanical strength, can effectively prevent viruses and bacteria from permeating, are not easy to damage, and can realize real complete protection.
Description
Technical Field
The invention relates to the technical field of latex materials, in particular to a self-antibacterial medical glove and a preparation method thereof.
Background
With the rapid development of the surgery and scientific technology, the modern operating room enters a new development stage. Due to the improvement of living standard and the attention on self health, the operation amount is increased sharply while the change of the current surgical operation tends to be deep and minimally invasive. In the face of the ever-expanding operation scale, the prevention and control of nosocomial infections become an extremely important link in the operation room. The use of medical gloves in surgery is of epoch-making significance and has become the primary means of reducing pathogen transmission. Medical gloves play a very important role in protecting patients and medical personnel as well as in the control of operating room infections. In recent years, approximately 600 to 650 billion pairs of latex gloves are consumed worldwide each year. However, medical gloves have many disadvantages and adverse reactions in production and use, and how to correctly select and use the gloves is of great significance for protecting patients and operating personnel, preventing infection of operation sites and preventing nosocomial infection.
Wearing medical gloves is an important measure for medical staff to carry out self-protection and prevent pathogenic bacteria cross infection in clinical work. On the premise that each hospital pays attention to standard prevention, gloves are also subjected to a series of evolution, and various functional gloves are produced at the same time. France developed an antibacterial glove that protected the physician from bacterial or viral infection in the event of an accidental rupture of the glove. The glove adopts a synthetic latex film structure, and a layer of disinfection and sterilization substance latex is added between two layers of latex films. Culture experiments show that the antibacterial gloves can effectively prevent scar and rash, AIDS and hepatitis virus infection. Not only protects the health of medical care personnel, but also prevents the spread of pathogenic bacteria. Gloves developed successfully in the united states to have a continuous bactericidal efficacy against various pathogens will be largely killed upon exposure of HIV, SPED filterable virus, hepatitis b virus, etc. to the antimicrobial agents contained in the gloves. With the improvement of living standard, people hope that the latex gloves not only have isolation and protection functions, but also the functional gloves are the main development direction of the latex gloves in future due to superiority.
At present, relevant researches at home and abroad are at the beginning stage, although some academic researches and patent documents appear, for example, silver inorganic antibacterial agents taking zirconium phosphate as a carrier, such as Dianthi and the like, are doped into medical catheter materials for slow release and antibacterial; the plum, Zhenjiang and the like add tributyl phosphate modified composite zinc oxide/silver nano-material as an antibacterial agent into natural rubber to prepare an antibacterial composite material; kurian et al have certain inhibitive ability against positive and negative gram bacteria by an organoclay/natural latex composite material synthesized by compounding organoclay and natural latex; the plum-Shigella steel and the like adopt a dip-coating method to prepare the antibacterial medical catheter and the like. However, in these researches, either a silver material which has a destructive effect on internal organs of a human body is added as an antibacterial agent, or antibiotics or organic matters with antibacterial performance are added to play a role in sterilization and bacteriostasis in a slow release manner, so that the medical gloves are not suitable for the human body or have the defect of time limitation, and the like, and the medical gloves are used as protective products for self-protection of medical workers and prevention of cross infection of pathogenic bacteria, so that the prior art cannot meet the requirement of preparing the self-antibacterial medical gloves with high mechanical strength and high virus and bacteria barrier performance.
Disclosure of Invention
Based on the above problems, the present invention aims to provide an antibacterial medical glove with high mechanical strength, high barrier property and antibacterial property and a preparation method thereof.
The above purpose of the invention is realized by the following technical scheme:
according to one aspect of the present invention, there is provided a method for preparing a self-antibacterial medical glove, comprising:
step S1, preparing nano antibacterial vulcanized latex by adopting natural latex and inorganic nano antibacterial compound dispersion liquid;
step S2, dipping the coagulant after washing the mold and drying;
and step S3, dipping the nano antibacterial vulcanized latex, shaping and drying to prepare the self-antibacterial medical glove.
Preferably, in step S1, the step of preparing the nano antibacterial vulcanized latex includes:
step S11, adding graphene oxide and zinc oxide into a high molecular dispersant for dispersion to prepare an inorganic nano antibacterial compound dispersion liquid;
step S12, placing the inorganic nano antibacterial compound dispersion liquid in an ultrasonic cleaning machine for ultrasonic treatment for 10-30 min, adding the inorganic nano antibacterial compound dispersion liquid after ultrasonic treatment into natural latex, stirring until the inorganic nano antibacterial compound dispersion liquid is uniformly dispersed, and adding a latex auxiliary agent to prepare a nano antibacterial compound latex solution;
and step S13, carrying out water vulcanization on the nano antibacterial matching latex solution, cooling, filtering and standing to prepare the nano antibacterial vulcanized latex.
Further, step S11 includes the following steps: weighing raw materials, wherein the raw materials comprise the following components in parts by weight: 5-20 parts of graphene oxide, 5-20 parts of zinc oxide and 1-15 parts of a water-based dispersant; adding the raw materials into a stirrer, uniformly stirring, and soaking for 1-5 hours; and (3) adding the mixture into a high-shear homogenizer for dispersing for 1-5 hours to obtain the inorganic nano antibacterial compound dispersion liquid.
Further, in step S12, the addition amount of the inorganic nano-antibacterial composite dispersion liquid is 0.1% to 15% of the natural rubber latex. More preferably, in step S12, the inorganic nano-antibacterial complex dispersion is added in an amount of 0.1% to 5% based on the natural rubber latex.
Further, in step S12, the latex auxiliary agent includes one or more of a stabilizer, a vulcanizing agent, an accelerator, an antioxidant, and an activator. Preferably, the stabilizer is one or two of casein and KOH, and the vulcanizing agent is sulfur; the accelerator is dithiocarbamate accelerator PX; the anti-aging agent is an anti-aging agent 264; the active agent is zinc carbonate.
Further, in step S13, the water vulcanization temperature is 55-80 ℃, and the temperature rise time is 30-60 min.
Preferably, in step S3, the nano antibacterial vulcanized latex is dipped once and shaped in two stages, wherein the slurry is shaped in one stage and then is leached and shaped in two stages.
Preferably, in step S3, after the step of dipping the nano-antibacterial vulcanized latex, the method further comprises: dipping a coating agent, homogenizing and curling, and then performing glue film drying for the first section, glue film drying for the second section and glue film drying for the third section; dipping hot water, dipping a separant, drying, demolding, soaking and washing with water, throwing water and removing a coating agent, and drying to obtain the self-antibacterial medical glove.
According to another aspect of the invention, the self-antibacterial medical gloves provided by the invention comprise raw materials and soft water, wherein the raw materials comprise the following components in parts by weight: 100 parts of natural latex, 0.1-15 parts of inorganic nano antibacterial compound dispersion liquid and 2.7-6 parts of latex auxiliary agent.
Preferably, the latex auxiliary agent comprises the following components in parts by weight: 0.2-0.5 part of stabilizer, 0.5-1.5 parts of vulcanizing agent, 0.5-1.0 part of accelerator, 0.5-1.4 parts of anti-aging agent and 1.0-1.5 parts of activator.
Preferably, the self-antibacterial medical gloves are prepared by the preparation method provided by the invention.
Compared with the prior art, the self-antibacterial medical gloves prepared by the invention have antibacterial performance, and the functions of sterilization and bacteriostasis are realized by adopting inorganic nano antibacterial materials; the novel protective film has a compact structure and high mechanical strength, can effectively prevent viruses and bacteria from permeating, is not easy to damage, and can realize real complete protection. Specifically, the invention adopts inorganic nano antibacterial compound dispersion liquid to modify natural latex to obtain nano antibacterial complex latex solution, water sulfurizes to obtain nano antibacterial vulcanized latex, and then the nano antibacterial vulcanized latex is added into a production line according to a medical glove production process to obtain the self-antibacterial medical gloves.
The inorganic nano antibacterial compound dispersion liquid prepared by the invention is used as a novel multifunctional inorganic material, has stable physical and chemical properties, high and easily obtained oxidation activity, and has the characteristics of no toxicity, no migration, strong antibacterial property and the like; has the characteristics of strong biocompatibility, biodegradability, rich active functional groups (functional groups) and the like; the structure and composition of the antibacterial agent have unique characteristics such as quantum size effect, interface effect and the like, the surface of the antibacterial agent is provided with a stable active group which can form active oxygen free radicals, and the active oxygen free radicals can be oxidized and killed under the action of oxygen atoms and oxygen free radicals by damaging bacterial cell membranes and inhibiting the synthesis of bacterial proteins and interfering the synthesis of bacterial cell walls and bacterial nucleic acids, so that the purposes of inhibiting bacterial reproduction and killing bacteria are achieved, and the antibacterial agent can be used as a long-acting, safe and efficient antibacterial agent.
The inorganic nano antibacterial compound dispersion liquid is applied to latex to prepare the self-antibacterial medical gloves, so that the gloves have the advantages of strong antibacterial force, good durability, wide antibacterial spectrum, no drug resistance, no toxicity to the environment and the like; the strength of the latex matrix and the compactness of the material are obviously enhanced. By uniformly and effectively dispersing the graphene oxide and the inorganic nano material in the latex matrix and utilizing the characteristics of the graphene oxide and the inorganic nano material, such as interface effect, small-size effect, huge specific surface area and the like, the graphene oxide, the inorganic nano material and the latex matrix are subjected to interface interaction, the compactness and mechanical strength of the medical glove are remarkably enhanced, and the mechanical strength of the medical glove and the barrier property to viruses and bacteria are improved.
Detailed Description
The technical solutions in the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Firstly, preparing inorganic nano antibacterial compound dispersion liquid.
Weighing the following raw materials: 5 parts of graphene oxide and 5 parts of zinc oxide are uniformly mixed, and 10 parts of a high molecular dispersing agent is added;
firstly, uniformly mixing graphene oxide and zinc oxide, then adding the graphene oxide and a polymer dispersant into a stirrer, uniformly stirring, and infiltrating for 2 hours; and then adding the mixture into a high-shear homogenizer to disperse for 3 hours, so that the inorganic material in the dispersion liquid reaches the nano level and is uniformly dispersed, and obtaining the inorganic nano antibacterial compound dispersion liquid. Wherein the macromolecular dispersant is a coupling agent.
And secondly, preparing a nano antibacterial complex latex solution.
Weighing the following raw materials: 100 parts of natural latex, 5 parts of inorganic nano antibacterial compound dispersion liquid, 0.2 part of casein, 0.15 part of KOH, 1 part of S, 0.8 part of accelerator, 1 part of anti-aging agent, 1.2 parts of activator and a proper amount of soft water. Wherein the soft water is calculated according to the total solid content of the compounded latex, and the total solid content of the compounded latex is 45-55 percent. The accelerator is composed of 40% dithiocarbamate PX; the vulcanizing agent is sulfur; the active agent is zinc carbonate.
Dispersing the weighed inorganic nano-antibacterial compound dispersion liquid for 20min by adopting ultrasonic waves, adding the inorganic nano-antibacterial compound dispersion liquid after ultrasonic treatment into 100 parts of natural latex, and uniformly stirring at a low speed to uniformly disperse the inorganic nano-antibacterial compound dispersion liquid in the natural latex; then adding latex auxiliary agent, stirring uniformly, and preparing to obtain the nano antibacterial complex latex solution.
And thirdly, preparing the nano antibacterial vulcanized latex.
And (3) putting the nano antibacterial matching latex solution into a water bath kettle for water vulcanization, wherein the vulcanization temperature is 65 ℃, the heating time is 40min, cooling is started when the chloroform value of the latex reaches two to three ends, then filtering is carried out, and the latex is parked for 2 days to prepare the nano antibacterial vulcanized latex.
Fourth, prepare from the medical glove of antibiotic
Preparing a coagulant, and preparing a coating agent and a release agent. Wherein the coating agent is an aqueous polyurethane solution. The separant is calcium chloride solution. The coagulant specifically comprises calcium chloride, a wetting agent and soft water, and the preparation method comprises the following steps: dissolving calcium chloride in a certain amount of soft water, and adding 0-1.5% of sodium dibutylnaphthalenesulfonate NF as a wetting agent, wherein the concentration of the calcium chloride is 8-12%.
1. Washing the mold, soaking the mold in hot water (at the temperature of 60-80 ℃) after washing the mold, soaking the coagulant, drying the coagulant for one section, drying the coagulant for two sections, and drying the coagulant for three sections to dry the coagulant thoroughly;
2. dipping the primary nano antibacterial vulcanized latex to form a glove adhesive film on the surface of the mold, homogenizing and shaping for one section, leaching (the temperature is 60-70 ℃), shaping for the second section, and spraying a code;
3. dipping a coating agent, homogenizing, performing edge curling, and then performing a first rubber film drying section, a second rubber film drying section and a third rubber film drying section;
4. and drying the adhesive film, then soaking in hot water, then soaking in a separant, drying, demolding, soaking in water, washing, throwing water, removing the coating agent, and finally drying to obtain the self-antibacterial medical glove.
Examples 2 to 3
The difference from the preparation method of example 1 is that: when preparing the nano antibacterial complex latex solution, 10 parts of the inorganic nano antibacterial complex dispersion liquid is added in example 2, and 15 parts of the inorganic nano antibacterial complex dispersion liquid is added in example 3.
Comparative example 1
The difference from the preparation method of example 1 is that: comparative example 1 does not add the inorganic nano-antibacterial complex dispersion when preparing the nano-antibacterial complex latex solution.
The invention carries out the relevant performance detection on the products of the examples 1-3 and the comparative example 1, and the specific steps are as follows:
the products obtained in examples 1 to 3 were tested for microorganisms. The detection result is as follows: the detection of the total number of bacterial colonies, the total number of fungal colonies, the coliform group, the staphylococcus aureus, the hemolytic streptococcus and the pseudomonas aeruginosa in the products prepared in the examples 1-3 all meet the standard (GB15979-2002 hygienic standards for disposable sanitary products).
The products obtained in examples 1 to 3 and comparative example 1 were tested for mechanical strength. The detection result is as follows: compared with comparative example 1, the tensile strength and elongation at break before aging are greatly improved on the premise of ensuring that the tensile strength and elongation at break after aging are stable in the products prepared in examples 1 to 3. The method comprises the following specific steps: comparative example 1 product: the tensile strength before and after aging is 28MPa and 24MPa respectively; elongation at break before and after aging was 789% and 792%, respectively. Examples 1-3 products: the tensile strength before aging is 25.7-31.2 MPa; the elongation at break before aging is 767% -837%; wherein, in example 1, when the addition amount of the inorganic nano antibacterial composite dispersion liquid is 5%, the physical properties of the product are optimal, and especially the tensile strength and the elongation at break of the product before aging can reach 31.2MPa and 837%. The aged tensile strength is 24.8-25.5 MPa; the elongation at break after aging is 739-787%.
The antibacterial performance of the products obtained in examples 1-2 was tested. Three samples are selected from the samples in the embodiment 1-2, the antibacterial performance of the escherichia coli is detected according to the detection standard (GB15979-2002), the total number of the bacterial colonies before and after 1h of oscillation is counted, and the detection result shows that: the difference of the bacteriostasis rates of the tested sample piece and the control sample piece in the example 1 is about 99.8 and is more than 26 percent, which indicates that the product prepared in the example 1 has an antibacterial effect. The bacteriostasis difference values of the tested sample piece and the control sample piece in the example 2 are respectively about 99.9 and are respectively more than 26 percent, which indicates that the product prepared in the example 2 has antibacterial effect.
The products obtained in examples 1-3 were tested for their bacteriostatic properties against E.coli and Staphylococcus aureus, respectively. The results show that: the product has antibacterial effect on Escherichia coli, and has antibacterial activity value of more than 5.3 (satisfying standard value of JIS Z2801:2010 with antibacterial activity value of more than 2.0) and antibacterial rate of more than 99.9%. The product has antibacterial effect on Escherichia coli, and has antibacterial activity value of more than 5.2 (satisfying standard value of JIS Z2801:2010 with antibacterial activity value of more than 2.0) and antibacterial rate of more than 99.9%.
The products obtained in examples 1 to 3 were each subjected to toxicological tests. Specifically, the skin allergy test of guinea pigs comprises 16 negative control groups, test groups (i.e. products obtained by the present application), and positive control groups. The test results show that: 24 hours and 48 hours after the excitation application is removed, no erythema or edema is seen on the excitation part of the animals of the negative control group and the test group, and the sensitization rate is 0 percent; the animals in the positive control group have erythema and edema with different degrees, the sensitization rate is 68.75 percent, the sensitization intensity of the positive control group is judged to be intensity sensitization, and the negative control group and the test group have no skin allergy.
Claims (10)
1. A method for preparing a self-antibacterial medical glove is characterized by comprising the following steps:
step S1, preparing nano antibacterial vulcanized latex by adopting natural latex and inorganic nano antibacterial compound dispersion liquid;
step S2, dipping the coagulant after washing the mold and drying;
and step S3, dipping the nano antibacterial vulcanized latex, shaping and drying to prepare the self-antibacterial medical glove.
2. The method of making self-antiseptic medical gloves of claim 1, wherein in step S1, the step of making nano-antiseptic vulcanized latex comprises:
step S11, adding graphene oxide and zinc oxide into a high molecular dispersant for dispersion to prepare an inorganic nano antibacterial compound dispersion liquid;
step S12, placing the inorganic nano antibacterial compound dispersion liquid in an ultrasonic cleaning machine for ultrasonic treatment for 10-30 min, adding the inorganic nano antibacterial compound dispersion liquid after ultrasonic treatment into natural latex, stirring until the inorganic nano antibacterial compound dispersion liquid is uniformly dispersed, and adding a latex auxiliary agent to prepare a nano antibacterial compound latex solution;
and step S13, carrying out water vulcanization on the nano antibacterial matching latex solution, cooling, filtering and standing to prepare the nano antibacterial vulcanized latex.
3. The method for preparing self-antibacterial medical gloves according to claim 2, wherein the step S11 includes the steps of:
weighing raw materials, wherein the raw materials comprise the following components in parts by weight: 5-20 parts of graphene oxide, 5-20 parts of zinc oxide and 1-15 parts of a water-based dispersant;
adding the raw materials into a stirrer, uniformly stirring, and soaking for 1-5 hours;
and (3) adding the mixture into a high-shear homogenizer for dispersing for 1-5 hours to obtain the inorganic nano antibacterial compound dispersion liquid.
4. The method of preparing self-antibacterial medical gloves according to claim 1, wherein in step S12, the inorganic nano-antibacterial composite dispersion is added in an amount of 0.1% to 15% based on the natural rubber latex.
5. The method for preparing self-antibacterial medical gloves according to claim 4, wherein in step S12, the inorganic nano-antibacterial composite dispersion is added in an amount of 0.1-5% of the natural rubber latex.
6. The method of preparing self-antiseptic medical gloves according to claim 1, wherein in step S12, the latex auxiliary agent includes one or more of a stabilizer, a vulcanizing agent, an accelerator, an anti-aging agent, and an activator.
7. The method for preparing self-antibacterial medical gloves according to claim 1, wherein in step S13, the water vulcanization temperature is 55 ℃ to 80 ℃ and the temperature rise time is 30min to 60 min.
8. The self-antimicrobial medical glove of claim 1, wherein the nano-antimicrobial vulcanized latex is dipped once and shaped in two stages in step S3, wherein the nano-antimicrobial vulcanized latex is homogenized and shaped in one stage and then leached and shaped in two stages.
9. The method for preparing self-antibacterial medical gloves according to claim 1, wherein step S3, after the step of dipping the nano-antibacterial vulcanized latex, further comprises:
dipping a coating agent, homogenizing and curling, and then performing glue film drying for the first section, glue film drying for the second section and glue film drying for the third section;
dipping hot water, dipping a separant, drying, demolding, soaking and washing with water, throwing water and removing a coating agent, and drying to obtain the self-antibacterial medical glove.
10. A self-antimicrobial medical glove, comprising: the self-antibacterial medical glove is prepared by the preparation method of any one of claims 1 to 9.
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