CN112469392A - 孕酮阴道内装置 - Google Patents

孕酮阴道内装置 Download PDF

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Publication number
CN112469392A
CN112469392A CN201980029137.0A CN201980029137A CN112469392A CN 112469392 A CN112469392 A CN 112469392A CN 201980029137 A CN201980029137 A CN 201980029137A CN 112469392 A CN112469392 A CN 112469392A
Authority
CN
China
Prior art keywords
progesterone
ring
intravaginal ring
intravaginal
vaginal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980029137.0A
Other languages
English (en)
Chinese (zh)
Inventor
康塞普西翁·涅托马格罗
埃琳娜·佩雷斯埃尔南多
热姆·莫斯科索德尔普拉多
哈维尔·苏亚雷斯阿尔马萨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Italfarmaco SA
Original Assignee
Italfarmaco SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco SA filed Critical Italfarmaco SA
Publication of CN112469392A publication Critical patent/CN112469392A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201980029137.0A 2018-03-21 2019-03-21 孕酮阴道内装置 Pending CN112469392A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18382190.9 2018-03-21
EP18382190.9A EP3542786A1 (en) 2018-03-21 2018-03-21 Progesterone intravaginal devices
PCT/EP2019/057074 WO2019180133A1 (en) 2018-03-21 2019-03-21 Progesterone intravaginal devices

Publications (1)

Publication Number Publication Date
CN112469392A true CN112469392A (zh) 2021-03-09

Family

ID=61768237

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980029137.0A Pending CN112469392A (zh) 2018-03-21 2019-03-21 孕酮阴道内装置

Country Status (7)

Country Link
US (1) US11278491B2 (enExample)
EP (2) EP3542786A1 (enExample)
JP (1) JP7391863B2 (enExample)
KR (1) KR102844796B1 (enExample)
CN (1) CN112469392A (enExample)
CA (1) CA3094420C (enExample)
WO (1) WO2019180133A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121243071A (zh) * 2025-10-30 2026-01-02 南京帝昌医药科技有限公司 一种雌激素阴道泡沫剂及其制备方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3542786A1 (en) 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices
CN114126710A (zh) * 2019-03-29 2022-03-01 B·马特尔 含有孕酮的eva分段式阴道内环

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816257A (en) * 1985-09-20 1989-03-28 Research & Education Institute, Harbor-Ucla Medical Center Inc. Method for producing an in vivo environment suitable for human embryo transfer
US5869081A (en) 1996-06-28 1999-02-09 The Population Council Progesterone vaginal ring for treatment of infertility
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
ES2648640T3 (es) 2008-02-04 2018-01-04 Ferring B.V. Anillos intravaginales monolíticos que comprenden progesterona y métodos de fabricación y usos de los mismos
US20170224823A1 (en) 2014-10-22 2017-08-10 International Partnership For Microbicides, Inc. Platinum-catalyzed silicone drug delivery devices and methods of use thereof
EP3542786A1 (en) 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121243071A (zh) * 2025-10-30 2026-01-02 南京帝昌医药科技有限公司 一种雌激素阴道泡沫剂及其制备方法

Also Published As

Publication number Publication date
CA3094420A1 (en) 2019-09-26
KR20200135443A (ko) 2020-12-02
WO2019180133A1 (en) 2019-09-26
CA3094420C (en) 2024-06-25
JP7391863B2 (ja) 2023-12-05
KR102844796B1 (ko) 2025-08-08
EP3768235A1 (en) 2021-01-27
JP2021518405A (ja) 2021-08-02
US11278491B2 (en) 2022-03-22
RU2020131251A (ru) 2022-04-22
US20210030666A1 (en) 2021-02-04
EP3542786A1 (en) 2019-09-25

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