CN112399887A - 检测芯片及其制备方法 - Google Patents

检测芯片及其制备方法 Download PDF

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CN112399887A
CN112399887A CN201980000847.0A CN201980000847A CN112399887A CN 112399887 A CN112399887 A CN 112399887A CN 201980000847 A CN201980000847 A CN 201980000847A CN 112399887 A CN112399887 A CN 112399887A
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detection
substrate
detection chip
dam
flow guide
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CN112399887B (zh
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殷雨丹
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BOE Technology Group Co Ltd
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BOE Technology Group Co Ltd
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
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    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
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    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions

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Abstract

一种检测芯片及其制备方法，该检测芯片(100)包括第一基板(110)、多个检测单元(120)和至少一个导流坝(130)。多个检测单元(120)位于第一基板(110)上，导流坝(130)位于第一基板(110)上，导流坝(130)沿第一路径延伸且位于相邻的检测单元(120)之间。该检测芯片(100)可以提高流场的稳定性和平行性，有助于提高免疫检测结果的准确度，且具有体积小、高通量等特点。

Description

PCT国内申请，说明书已公开。

Claims (21)

  1. PCT国内申请，权利要求书已公开。
CN201980000847.0A 2019-06-17 2019-06-17 检测芯片及其制备方法 Active CN112399887B (zh)

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PCT/CN2019/091555 WO2020252627A1 (zh) 2019-06-17 2019-06-17 检测芯片及其制备方法

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CN112399887A true CN112399887A (zh) 2021-02-23
CN112399887B CN112399887B (zh) 2023-02-07

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US (1) US20220050100A1 (zh)
EP (1) EP3984639A4 (zh)
CN (1) CN112399887B (zh)
WO (1) WO2020252627A1 (zh)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1858593A (zh) * 2006-03-23 2006-11-08 厦门大学 生物芯片专用亲疏水模式片基
CN105689029A (zh) * 2016-01-29 2016-06-22 深圳市国赛生物技术有限公司 一种微流控芯片及其使用方法
CN109283231A (zh) * 2017-07-20 2019-01-29 京东方科技集团股份有限公司 一种医用检测基板、医用检测芯片及医用检测系统
CN109590039A (zh) * 2019-01-18 2019-04-09 京东方科技集团股份有限公司 一种微流控组件、微流控芯片及其制备方法

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* Cited by examiner, † Cited by third party
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AU2003248273A1 (en) * 2002-07-12 2004-02-02 Mitsubishi Chemical Corporation Analytical chip, analytical chip unit, analyzing apparatus, method of analysis using the apparatus, and method of producing the analytical chip
US20100304501A1 (en) * 2007-11-09 2010-12-02 Electronics And Telecommunicaations Research Insti Bio lab-on-a-chip and method of fabricating and operating the same
EP2419216A1 (en) * 2009-04-15 2012-02-22 Koninklijke Philips Electronics N.V. Microfluidic device comprising sensor
TWI418858B (zh) * 2009-09-23 2013-12-11 Prime View Int Co Ltd 彩色濾光基板及彩色顯示裝置
KR101443074B1 (ko) * 2012-11-26 2014-09-26 한국전기연구원 마이크로 채널의 수동형 펌프 구현을 위한 친수성 필라 제작 방법
WO2015054546A1 (en) * 2013-10-10 2015-04-16 Song Diagnostic Research Llc. Improved lateral flow assays
EP3080300B1 (en) * 2013-12-11 2020-09-02 Genapsys Inc. Systems and methods for biological analysis and computation
CN207102625U (zh) * 2017-06-29 2018-03-16 宁波奥丞生物科技有限公司 一种微流体分析盒
CN108816300B (zh) * 2018-07-02 2020-05-01 京东方科技集团股份有限公司 一种微流控芯片、功能装置及其制作方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1858593A (zh) * 2006-03-23 2006-11-08 厦门大学 生物芯片专用亲疏水模式片基
CN105689029A (zh) * 2016-01-29 2016-06-22 深圳市国赛生物技术有限公司 一种微流控芯片及其使用方法
CN109283231A (zh) * 2017-07-20 2019-01-29 京东方科技集团股份有限公司 一种医用检测基板、医用检测芯片及医用检测系统
CN109590039A (zh) * 2019-01-18 2019-04-09 京东方科技集团股份有限公司 一种微流控组件、微流控芯片及其制备方法

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CN112399887B (zh) 2023-02-07
EP3984639A4 (en) 2023-03-22
EP3984639A1 (en) 2022-04-20
WO2020252627A1 (zh) 2020-12-24
US20220050100A1 (en) 2022-02-17

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