CN112386624A - Externally applied medicament for treating psoriasis and preparation method thereof - Google Patents

Externally applied medicament for treating psoriasis and preparation method thereof Download PDF

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Publication number
CN112386624A
CN112386624A CN202110053198.XA CN202110053198A CN112386624A CN 112386624 A CN112386624 A CN 112386624A CN 202110053198 A CN202110053198 A CN 202110053198A CN 112386624 A CN112386624 A CN 112386624A
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parts
american ginseng
alum
treating psoriasis
snake skin
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王西康
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Dermatology (AREA)
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Abstract

The invention discloses an external application medicament for treating psoriasis and a preparation method thereof, wherein the external application medicament comprises the following raw materials in percentage by mass: 10-30 parts of cow leather; 5-25 parts of American ginseng; 3-20 parts of bitter bile; 3-20 parts of alum; 3-20 parts of Chinese pennisetum herb and 3-20 parts of snake skin. Has the advantages that: by adopting the pure natural materials for decoction, the traditional Chinese medicine composition has no allergen and no additive, can adapt to sensitive skin and reduce anaphylactic reaction; the preparation is simple, the materials are easy to obtain, and the treatment cost of the psoriasis can be reduced; the traditional Chinese medicine has short treatment period, can take effect after being externally applied for seven days, takes effect quickly, and can increase the confidence of a patient in treating diseases.

Description

Externally applied medicament for treating psoriasis and preparation method thereof
Technical Field
The invention relates to the technical field of external application for skin diseases, in particular to an external application medicament for treating psoriasis and a preparation method thereof.
Background
Psoriasis, commonly known as psoriasis, is characterized by papules and erythema of different sizes, covered by silvery scales on the surface, with clear borders and good hair on the scalp, the extremities and the back. It is a common chronic, recurrent, inflammatory skin disease characterized by the repeated appearance of multiple silvery white, dry scales on erythema. Psoriasis is one of three kinds of intractable skin diseases, is difficult to cure, has high recurrence rate, brings inconvenience to the life of patients, and causes great mental stress and physical pain to the patients.
Most of the existing psoriasis treatment medicines are chemically synthesized, and the contained chemical components are easy to cause anaphylactic reaction when being used by patients with fragile skin; and the existing medicine has the defects of long treatment period, slow effect and the like when used for treating psoriasis.
Disclosure of Invention
The present invention aims to solve the above problems and provide an external application medicament for treating psoriasis, wherein a preferable technical scheme of the technical schemes provided by the present invention comprises: simple preparation, low cost, shortened treatment period, quick response, no adverse reaction and other technical effects, and is explained in detail below.
In order to achieve the purpose, the invention provides the following technical scheme:
the invention provides an external application medicament for treating psoriasis, which comprises the following raw materials in percentage by mass: 10-30 parts of cow leather; 5-25 parts of American ginseng; 3-20 parts of bitter bile; 3-20 parts of alum; 3-20 parts of Chinese pennisetum herb and 3-20 parts of snake skin.
Preferably, the feed also comprises 40-80 parts of eggs and 50-100 parts of sesame oil.
Preferably, the raw materials comprise the following mass fractions: 21-30 parts of cow leather; 16-25 parts of American ginseng; 11-20 parts of bitter bile; 11-20 parts of alum; 11-20 parts of Chinese stellera roots and herbs; 11-20 parts of snake skin; 60-80 parts of eggs and 76-100 parts of sesame oil.
Preferably, the raw materials comprise the following mass fractions: 26 parts of cow leather; 21 parts of American ginseng; 16 parts of bitter bile; 16 parts of alum; 16 parts of Chinese stellera roots and herbs; 16 parts of snake skin; 70 parts of eggs and 88 parts of sesame oil.
Preferably, the raw materials comprise the following mass fractions: 10-20 parts of cow leather; 5-15 parts of American ginseng; 3-10 parts of bitter bile; 3-10 parts of alum; 3-10 parts of Chinese stellera roots and herbs; 3-10 parts of snake skin; 40-59 parts of eggs and 50-75 parts of sesame oil.
Preferably, the raw materials comprise the following mass fractions: 15 parts of cow leather; 10 parts of American ginseng; 6.5 parts of bitter bile; 6.5 parts of alum; 6.5 parts of Chinese stellera roots and herbs; 6.5 parts of snake skin; 50 parts of eggs and 63 parts of sesame oil.
Preferably, the raw materials comprise the following mass fractions: 20 parts of cow leather; 15 parts of American ginseng; 10 parts of bitter bile; 10 parts of rice with white rice; 10 parts of Chinese stellera roots and herbs; 10 parts of snake skin.
A preparation method of an external application medicament for treating psoriasis comprises the following processing steps:
s110, raw material processing: baking and drying cow hide, baking and drying snake skin, drying American ginseng, alum and Chinese pennisetum herb, and crushing the dried American ginseng, alum and Chinese pennisetum herb together with the cow hide and the snake skin into powder to form raw material powder;
s120, decocting: adding oleum Sesami into a pan, adding the raw material powder and fel Ursi juice into the pan, heating, adding ovum gallus Domesticus into the pan, and decocting to obtain black paste.
In conclusion, the beneficial effects of the invention are as follows: 1. by adopting the pure natural materials for decoction, the traditional Chinese medicine composition has no allergen and no additive, can adapt to sensitive skin and reduce anaphylactic reaction;
2. the preparation is simple, the materials are easy to obtain, and the treatment cost of the psoriasis can be reduced;
3. the traditional Chinese medicine has short treatment period, can take effect after being externally applied for seven days, takes effect quickly, and can increase the confidence of a patient in treating diseases.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
The invention provides an external application medicament for treating psoriasis, which comprises the following raw materials in percentage by mass: 10-30 parts of cow leather; 5-25 parts of American ginseng; 3-20 parts of bitter bile; 3-20 parts of alum; 3-20 parts of Chinese stellera roots and herbs; 3-20 parts of snake skin; 40-80 parts of eggs and 50-100 parts of sesame oil.
A preparation method of an external application medicament for treating psoriasis comprises the following processing steps:
s110, raw material processing: baking and drying cow hide, baking and drying snake skin, drying American ginseng, alum and Chinese pennisetum herb, and crushing the dried American ginseng, alum and Chinese pennisetum herb together with the cow hide and the snake skin into powder to form raw material powder;
s120, decocting: adding oleum Sesami into a pan, adding the raw material powder and fel Ursi juice into the pan, heating, adding ovum gallus Domesticus into the pan, and decocting to obtain black paste. After the reduction is finished, the black paste ointment is smeared on the affected part, and then is wrapped by medical adhesive tape or medical gauze, and the ointment is externally applied for seven days, so that the effect can be achieved; if the ointment falls off or the dressing falls off in less than seven days, the dressing should be replaced in time and then bound again.
The specific embodiment is as follows:
example 1
The material comprises the following raw materials in percentage by mass: 21 parts of cow leather; 16 parts of American ginseng; 11 parts of bitter bile; 11 parts of alum; 11 parts of Chinese stellera roots and herbs; 11 parts of snake skin; 60 parts of eggs and 76 parts of sesame oil.
Example 2
The material comprises the following raw materials in percentage by mass: 30 parts of cow leather; 25 parts of American ginseng; 20 parts of bitter bile; 20 parts of alum; 20 parts of Chinese stellera roots and herbs; 20 parts of snake skin; 80 parts of eggs and 100 parts of sesame oil.
Example 3.
The material comprises the following raw materials in percentage by mass: 26 parts of cow leather; 21 parts of American ginseng; 16 parts of bitter bile; 16 parts of alum; 16 parts of Chinese stellera roots and herbs; 16 parts of snake skin; 70 parts of eggs and 88 parts of sesame oil.
Example 4
The material comprises the following raw materials in percentage by mass: 10 parts of cow leather; 5 parts of American ginseng; 3 parts of bitter bile; 3 parts of alum; 3 parts of Chinese stellera roots and herbs; 3 parts of snake skin; 40 parts of eggs and 50 parts of sesame oil.
Example 5
The material comprises the following raw materials in percentage by mass: 20 parts of cow leather; 15 parts of American ginseng; 10 parts of bitter bile; 10 parts of alum; 10 parts of Chinese stellera roots and herbs; 10 parts of snake skin; 59 parts of eggs and 75 parts of sesame oil.
Example 6
The material comprises the following raw materials in percentage by mass: 15 parts of cow leather; 10 parts of American ginseng; 6.5 parts of bitter bile; 6.5 parts of alum; 6.5 parts of Chinese stellera roots and herbs; 6.5 parts of snake skin; 50 parts of eggs and 63 parts of sesame oil.
Example 7
The material comprises the following raw materials in percentage by mass: 20 parts of cow leather; 15 parts of American ginseng; 10 parts of bitter bile; 10 parts of rice with white rice; 10 parts of Chinese stellera roots and herbs; 10 parts of snake skin.
Example 8
The material comprises the following raw materials in percentage by mass: 20 parts of cow leather; 10 parts of American ginseng; 8 parts of bitter bile; 8 parts of cooked rice; 8 parts of Chinese stellera roots and herbs; 10 parts of snake skin.
Example 9
The material comprises the following raw materials in percentage by mass: 20 parts of cow leather; 15 parts of American ginseng; 5 parts of bitter bile; 5 parts of rice with white rice; 5 parts of Chinese stellera roots and herbs; 5 parts of snake skin.
Example 10
The material comprises the following raw materials in percentage by mass: 15 parts of cow leather; 10 parts of American ginseng; 10 parts of bitter bile; 10 parts of rice with white rice; 10 parts of Chinese stellera roots and herbs; 10 parts of snake skin.
The medicament prepared by the materials is decocted by adopting a pure natural material, has no allergen and no additive, can adapt to sensitive skin, and reduces anaphylactic reaction; the preparation is simple, the materials are easy to obtain, and the treatment cost of the psoriasis can be reduced; the external application has short treatment period, the external application can be effective in seven days, the effect is quick, the confidence of a patient in treating diseases can be increased, the skin of a patient with slight symptoms is recovered to be normal after the external application for seven days, and the psoriasis can be radically treated.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (8)

1. The externally applied medicament for treating psoriasis is characterized by comprising the following raw materials in percentage by mass: 10-30 parts of cow leather; 5-25 parts of American ginseng; 3-20 parts of bitter bile; 3-20 parts of alum; 3-20 parts of Chinese pennisetum herb and 3-20 parts of snake skin.
2. The external medicament for treating psoriasis according to claim 1, wherein: also comprises 40-80 parts of eggs and 50-100 parts of sesame oil.
3. The external medicament for treating psoriasis according to claim 2, wherein: the material comprises the following raw materials in percentage by mass: 21-30 parts of cow leather; 16-25 parts of American ginseng; 11-20 parts of bitter bile; 11-20 parts of alum; 11-20 parts of Chinese stellera roots and herbs; 11-20 parts of snake skin; 60-80 parts of eggs and 76-100 parts of sesame oil.
4. The external medicament for treating psoriasis according to claim 3, wherein: the material comprises the following raw materials in percentage by mass: 26 parts of cow leather; 21 parts of American ginseng; 16 parts of bitter bile; 16 parts of alum; 16 parts of Chinese stellera roots and herbs; 16 parts of snake skin; 70 parts of eggs and 88 parts of sesame oil.
5. The external medicament for treating psoriasis according to claim 2, wherein: the material comprises the following raw materials in percentage by mass: 10-20 parts of cow leather; 5-15 parts of American ginseng; 3-10 parts of bitter bile; 3-10 parts of alum; 3-10 parts of Chinese stellera roots and herbs; 3-10 parts of snake skin; 40-59 parts of eggs and 50-75 parts of sesame oil.
6. The external medicament for treating psoriasis according to claim 5, wherein: the material comprises the following raw materials in percentage by mass: 15 parts of cow leather; 10 parts of American ginseng; 6.5 parts of bitter bile; 6.5 parts of alum; 6.5 parts of Chinese stellera roots and herbs; 6.5 parts of snake skin; 50 parts of eggs and 63 parts of sesame oil.
7. The external medicament for treating psoriasis according to claim 1, wherein: the material comprises the following raw materials in percentage by mass: 20 parts of cow leather; 15 parts of American ginseng; 10 parts of bitter bile; 10 parts of rice with white rice; 10 parts of Chinese stellera roots and herbs; 10 parts of snake skin.
8. The process for preparing externally applied medicine for treating psoriasis as claimed in claim 2, which comprises the following steps:
s110, raw material processing: baking and drying cow hide, baking and drying snake skin, drying American ginseng, alum and Chinese pennisetum herb, and crushing the dried American ginseng, alum and Chinese pennisetum herb together with the cow hide and the snake skin into powder to form raw material powder;
s120, decocting: adding oleum Sesami into a pan, adding the raw material powder and fel Ursi juice into the pan, heating, adding ovum gallus Domesticus into the pan, and decocting to obtain black paste.
CN202110053198.XA 2021-01-15 2021-01-15 Externally applied medicament for treating psoriasis and preparation method thereof Pending CN112386624A (en)

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CN202110053198.XA CN112386624A (en) 2021-01-15 2021-01-15 Externally applied medicament for treating psoriasis and preparation method thereof

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Application Number Priority Date Filing Date Title
CN202110053198.XA CN112386624A (en) 2021-01-15 2021-01-15 Externally applied medicament for treating psoriasis and preparation method thereof

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106074732A (en) * 2016-07-21 2016-11-09 吕令中 A kind of antipsoriatics thing and preparation method thereof
CN108451991A (en) * 2018-04-13 2018-08-28 刘鹏 A kind of psoriasis formula and preparation method thereof
CN109423420A (en) * 2017-08-23 2019-03-05 青岛生鲜馆电子商务有限公司 Health care product egg vinegar

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106074732A (en) * 2016-07-21 2016-11-09 吕令中 A kind of antipsoriatics thing and preparation method thereof
CN109423420A (en) * 2017-08-23 2019-03-05 青岛生鲜馆电子商务有限公司 Health care product egg vinegar
CN108451991A (en) * 2018-04-13 2018-08-28 刘鹏 A kind of psoriasis formula and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李秀云等: "冰椒散外用治银屑病", 《辽宁中医杂志》 *
程爵棠，等: "《常见病中成药证治妙方》", 31 July 2017, 河南科学技术出版社 *

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Application publication date: 20210223