CN112384248A - 预防或治疗突触核蛋白病的包含c-src的表达或活性抑制剂的药物组合物 - Google Patents

预防或治疗突触核蛋白病的包含c-src的表达或活性抑制剂的药物组合物 Download PDF

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CN112384248A
CN112384248A CN201980046255.2A CN201980046255A CN112384248A CN 112384248 A CN112384248 A CN 112384248A CN 201980046255 A CN201980046255 A CN 201980046255A CN 112384248 A CN112384248 A CN 112384248A
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src
syn
activation
alpha
expression
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朴相冕
崔有利
金载奉
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Ajou University Industry Academic Cooperation Foundation
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CN201980046255.2A 2018-06-08 2019-06-07 预防或治疗突触核蛋白病的包含c-src的表达或活性抑制剂的药物组合物 Pending CN112384248A (zh)

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KR20180066005 2018-06-08
KR10-2018-0066005 2018-06-08
PCT/KR2019/006870 WO2019235876A1 (ko) 2018-06-08 2019-06-07 C-src의 발현 또는 활성 억제제를 포함하는 시누클레인병증의 예방 또는 치료용 약학 조성물

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US (1) US20210101966A1 (ko)
KR (1) KR102261005B1 (ko)
CN (1) CN112384248A (ko)
WO (1) WO2019235876A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113827729A (zh) * 2021-11-08 2021-12-24 复旦大学附属中山医院 Pd-1/pd-l1拮抗剂在抗癫痫上的应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102663668B1 (ko) * 2020-10-08 2024-05-08 상지대학교산학협력단 Trdn을 포함하거나 조절하는 파킨슨병용 약제학적 조성물 및 그 치료제

Citations (2)

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US20090258814A1 (en) * 2008-04-09 2009-10-15 Scott Thomas Brady Method for treating a synucleinopathy
GB201002676D0 (en) * 2007-08-14 2010-04-07 Univ Leuven Kath Inhibition of alpha synuclein toxicity

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US10660957B2 (en) * 2013-06-13 2020-05-26 Yale University Compositions and methods for treating an Aβ-modulated disease or disorder or improving cognition in a subject
US10085976B2 (en) * 2015-07-15 2018-10-02 Ajou University Industry-Academic Cooperation Foundation Pharmaceutical composition for preventing or treating neurodegenerative diseases
KR20210079214A (ko) * 2019-12-19 2021-06-29 주식회사 스탠다임 시누클레인병증 치료 조성물
WO2021125810A1 (en) * 2019-12-19 2021-06-24 Standigm Inc. Composition for treating synucleinopathies

Patent Citations (2)

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GB201002676D0 (en) * 2007-08-14 2010-04-07 Univ Leuven Kath Inhibition of alpha synuclein toxicity
US20090258814A1 (en) * 2008-04-09 2009-10-15 Scott Thomas Brady Method for treating a synucleinopathy

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
SAVITA KHANNA 等: "Regulation of c-Src Activity in Glutamate-induced Neurodegeneration", 《THE JOURNAL OF BIOLOGICAL CHEMISTRY》 *
SAVITA KHANNA 等: "Regulation of c-Src Activity in Glutamate-induced Neurodegeneration", 《THE JOURNAL OF BIOLOGICAL CHEMISTRY》, vol. 282, no. 32, 10 August 2007 (2007-08-10), pages 23482 - 23490, XP055662366, DOI: 10.1074/jbc.M611269200 *
SEONG SU KANG 等: "α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation", 《PNAS》 *
SEONG SU KANG 等: "α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation", 《PNAS》, vol. 114, no. 5, 31 January 2017 (2017-01-31), pages 1183, XP055662370, DOI: 10.1073/pnas.1618627114 *
SINGH, R.等: "PKC-δ binds to E-cadherin and mediates EGF-induced cell scattering", 《EXPERIMENTAL CELL RESEARCH》, vol. 315, pages 1903 *
何一昕 等: "突触核蛋白病中α-syn聚集及播散的机制研究", 《中国实用神经疾病杂志》 *
何一昕 等: "突触核蛋白病中α-syn聚集及播散的机制研究", 《中国实用神经疾病杂志》, vol. 19, no. 04, 29 February 2016 (2016-02-29), pages 77 - 79 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113827729A (zh) * 2021-11-08 2021-12-24 复旦大学附属中山医院 Pd-1/pd-l1拮抗剂在抗癫痫上的应用

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KR20190139780A (ko) 2019-12-18
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