CN112294865B - Traditional Chinese medicine preparation for treating suppurative otitis media and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating suppurative otitis media and preparation method thereof Download PDF

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CN112294865B
CN112294865B CN202011368890.3A CN202011368890A CN112294865B CN 112294865 B CN112294865 B CN 112294865B CN 202011368890 A CN202011368890 A CN 202011368890A CN 112294865 B CN112294865 B CN 112294865B
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otitis media
oak
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chinese medicine
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CN112294865A (en
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李富震
苏金峰
隋博文
刘刚刚
李阳光
李金晋
李富超
李海清
高雪娇
贲珊
赵春森
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Heilongjiang University of Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Abstract

The invention discloses a traditional Chinese medicine preparation for treating suppurative otitis media and a preparation method thereof, wherein the traditional Chinese medicine preparation comprises the following raw materials: ramulus Oak, Olibanum, Myrrha, Borneolum Syntheticum, Borax, Catechu, and dried Alumen; the weight parts of the raw materials are as follows: 5-20 parts of oak branches, 1-10 parts of frankincense, 1-10 parts of myrrh, 1-10 parts of borneol, 1-10 parts of borax, 1-10 parts of catechu and 1-10 parts of dried alum. The invention has the advantages of less medicine, low price of raw materials, direct external application by blowing ear, simple operation, good curative effect on acute and chronic suppurative otitis media, and high cure rate of more than 90 percent.

Description

Traditional Chinese medicine preparation for treating suppurative otitis media and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for treating suppurative otitis media and a preparation method thereof.
Background
Suppurative otitis media is classified into acute suppurative otitis media and chronic suppurative otitis media. Acute suppurative otitis media refers to acute suppurative inflammation of the mucosa of the middle ear, which is caused by infection caused by invasion of suppurative bacteria into the middle ear through the eustachian tube or the traumatic tympanic membrane, common pathogenic bacteria are hemolytic streptococcus, the lesion part is mainly positioned in the tympanic cavity, other related parts of the middle ear can be affected, the clinical manifestations of ear pain, suppuration, hearing loss, tinnitus and the like are shown, the general symptoms with different degrees can be accompanied, and acute congestion, perforation and the like of the eardrum can be detected. Chronic suppurative otitis media refers to chronic suppurative inflammation of middle ear, lesions invading the mucosa, periosteum or deep bone of middle ear, and chronic mastoiditis always existed, and the clinical manifestations are characterized by long-term or intermittent suppuration in ear, perforation of tympanic membrane and hearing loss, and can be divided into simple type, bone ulcer type and cholesteatomia type according to the lesion degree and nature.
Suppurative otitis media is a common disease of infants and children. 80% of children have at least one otitis media, the disease usually occurs between 6 months and 4 years old, and 30% -40% of children have recurrent suppurative otitis media. At present, the conventional treatment of acute suppurative otitis media by western medicines mainly adopts the systemic or local application of antibiotics to control infection, smooth drainage and the like, most of the conventional treatment methods can only relieve symptoms, the acute suppurative otitis media is difficult to prevent from being converted into chronic, the curative effect is not ideal enough, so that the acute suppurative otitis media can be repeatedly bought for a long time, the history of the suppurative otitis media of some patients even lasts for decades, the auditory meatus of the patients is purulent, the hearing of the patients is reduced, and the work and the life are influenced; for severe patients such as chronic suppurative otitis media bone ulcer type drainage unsmooth patients or gall bladder tumor type patients, the operation treatment is adopted, the pain is great, and the cost is high. The traditional Chinese medicine for treating suppurative otitis media is to take the suppurative otitis media orally by decoction according to syndrome differentiation and classification, the curative effect varies from person to person, and young patients have poor medicine taking compliance and few acupuncture and moxibustion treatment reports.
Disclosure of Invention
The invention aims to solve the problems and provides a traditional Chinese medicine preparation for treating suppurative otitis media and a preparation method thereof. In order to achieve the purpose, the technical scheme of the invention is as follows:
a traditional Chinese medicine preparation for treating suppurative otitis media comprises the following raw materials: ramulus Oak, Olibanum, Myrrha, Borneolum Syntheticum, Borax, Catechu, and dried Alumen; the weight parts of the raw materials are as follows: 5-20 parts of oak branches, 1-10 parts of frankincense, 1-10 parts of myrrh, 1-10 parts of borneol, 1-10 parts of borax, 1-10 parts of catechu and 1-10 parts of dried alum.
In a further optimized scheme, the weight parts of the raw materials are as follows: 15-20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
In a further optimized scheme, the weight parts of the raw materials are as follows: 20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
In a further optimized scheme, the weight parts of the raw materials are as follows: 10 parts of oak branches, 3 parts of frankincense, 3 parts of myrrh, 4 parts of borneol, 4 parts of borax, 4 parts of catechu and 4 parts of dried alum.
In a further optimized scheme, the weight parts of the raw materials are as follows: 8 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 4 parts of borneol, 5 parts of borax, 4 parts of catechu and 5 parts of dried alum.
Furthermore, the Chinese medicinal preparation is in the form of powder.
The preparation method of the traditional Chinese medicine preparation for treating suppurative otitis media comprises the following preparation steps:
a. putting the oak branches into hot sand, stir-frying, taking out when the temperature of the sand is 140-180 ℃ until the surfaces of the oak branches are scorched black, screening to remove sand, and cooling to obtain oak branch charcoal;
b. parching Olibanum and Myrrha in a pan, spraying rice vinegar, parching, and cooling to obtain Olibanum and Myrrha;
c. mixing the oak branch charcoal, the prepared frankincense, the prepared myrrh, the borneol, the borax, the catechu and the dried alum, crushing and sieving to obtain undersize powder, namely the traditional Chinese medicine preparation.
Further, the sieving in step c is 120 mesh sieving.
Further, the temperature of the sand in step a is 150 ℃.
Pharmacological description:
the oak branches are bitter and sour in taste and cool in nature, can clear away heat and toxic materials, relieve swelling and pain, and dredge orifices and restore hearing, have good treatment effects on common earache, ear distension, ear stuffiness, hearing loss and the like of patients with suppurative otitis media, can gather dampness and heal sores when used, reduce local exudation, and are monarch drugs of the formula.
Borneol is pungent and fragrant, has the effects of clearing skin and meat, dispersing fire toxin, and relieving swelling and pain, and can be used for cooling by using body temperature; borax is sweet and salty in flavor and cool in smell, and can resolve swelling and dissipate nodulation in clearing heat. The two herbs have the effects of clearing heat, relieving swelling, removing toxicity and relieving pain, and are ministerial herbs of the recipe. After the ear-washing liquid is externally used for ear washing, a patient can feel cool in the ear canal within one hour, and the swelling and pain is relieved, so that the syndrome can be marked.
The pungent herbs of Ru Xiang and Mo Yao are used together as assistant drugs in the recipe, because they are warm and unblocking, they can not only prevent other herbs in the recipe from obstructing qi and blood, but also remove blood stasis and relieve pain, promote tissue regeneration and heal wound.
Catechu and dried alum are astringent and cool in flavor, can astringe dampness, promote tissue regeneration and heal wound, and can reduce local wound surface exudation at the affected part, and pharmacological studies show that the two herbs have inhibitory effect on various suppurative bacteria, and are guiding drugs of the recipe. After the ear-washing liquid is externally used for ear washing, a patient can consciously reduce the exudation of the auditory meatus within two days, and the swelling pain is relieved, so that the syndrome can be marked.
The invention has the beneficial effects that:
the invention is mainly applied to patients with simple type acute suppurative otitis media and chronic suppurative otitis media and patients with smooth bone ulcer drainage, and also to patients with repeated postoperative conditions. The invention has the advantages of less medicine, low price of raw materials, direct external application by blowing ear, simple operation, good curative effect on acute and chronic suppurative otitis media, high cure rate of more than 90 percent, no obvious toxic or side effect and good safety.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1:
a traditional Chinese medicine preparation for treating suppurative otitis media comprises the following raw materials: ramulus Oak, Olibanum, Myrrha, Borneolum Syntheticum, Borax, Catechu, and dried Alumen; the weight parts of the raw materials are as follows: 5-20 parts of oak branches, 1-10 parts of frankincense, 1-10 parts of myrrh, 1-10 parts of borneol, 1-10 parts of borax, 1-10 parts of catechu and 1-10 parts of dried alum.
The preparation method comprises the following steps:
a. the oak branches are cut into about 3 cm small sections for standby. Heating clean coarse sand in a pot with strong fire until the sand is smooth and can be easily turned over by using a shovel (about 150 ℃), adding oak branches, continuously turning and frying until the surfaces of the oak branches are scorched black, taking out the oak branches, and sieving the sand by using an iron sieve to cool the sand to obtain oak branch charcoal;
b. beating Olibanum and Myrrha into small pieces, parching with slow fire until the surface is slightly soluble, spraying rice vinegar, parching for two or three times until the outer layer is shiny, cooling to obtain Olibanum and Myrrha;
c. mixing the oak branch charcoal, the prepared frankincense, the prepared myrrh, the borneol, the borax, the catechu and the dried alum according to the proportion, crushing, and sieving by a 120-mesh sieve to obtain the used fine powder. Clinically, it is applied to the local auditory canal by blowing outside the ear.
Example 2:
optimization was performed on the basis of example 1.
The weight parts of the raw materials are as follows: 15-20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
The procedure was the same as in example 1.
Example 3:
optimization was performed on the basis of example 1.
The weight parts of the raw materials are as follows: 20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
The procedure was the same as in example 1.
The invention relates to a Chinese medicinal preparation for treating suppurative otitis media, in particular to ulcer removing powder. The ulcer eliminating powder in the application example 1 is the traditional Chinese medicine preparation prepared according to the example 2, and the part amount of the oak branches fluctuates according to different disease conditions after each diagnosis. The ulcer eliminating powder in application example 2 is the traditional Chinese medicine preparation prepared according to example 3. The application examples 3 to 30 adopt the mixture ratio in the example 1, and the actual amount of each component is different according to different disease conditions.
Application example 1:
zhao, male, 10 years old, Dulbert Mongolian autonomous county, Heilongjiang province. Initial diagnosis: year 2019, month 9, and day 16. Suppurative otitis media after cold has remained for three years, the suppurative otitis media is taken once or twice a month, swelling and pain of right ear are caused when the suppurative otitis media is taken out, pus flows and water flows, fever is accompanied, ibuprofen is mainly used for being matched with local inflammation diminishing treatment of auditory canals, the local inflammation diminishing treatment can be gradually relieved for a plurality of days, and the curative effect of a plurality of hospitals and three hospitals who visit successively is not ideal. One week before the infant is hot, the body temperature is 38.4 ℃, pain occurs in the right ear, pus is formed, and the ear canal is red and swollen, local moist and pus is attached to the ear canal.
Prescription: xiaoyangsan powder with three spoons is externally used for ear blowing; then the sterilized dry cotton ball is tightly plugged into the external opening of the auditory canal until the next visit, and the ear canal can be taken out without air leakage; when sleeping, the left side lies on the left side, and the ear of the patient faces upward. During the application, the ears may be itchy, which is a good indication for growing muscle and is not easy to dig out. Pungent and pungent irritations and hair materials are contraindicated. The diagnosis is made every other day.
And B, diagnosis: 9 months and 18 days. The mother reports: after the external use of the medicine for eliminating ulcer is blown to the ear, the pain of the right ear on the next day is obviously relieved. Diagnosis: the body temperature is normal, the pain of the right ear is no longer present, and the right ear is still moist locally after inspection. The three small spoons above are used, and the above is prohibited for external application. The diagnosis is made every other day.
Three diagnoses: 9 months and 20 days. The pain of the right ear did not occur in the last two days, and the right ear was examined to be dry and comfortable locally. The two spoons above are used, and the above method is applied externally, so pungent stimulation and hair growth are avoided for one week, and no further diagnosis is needed.
Telephone follow-up in 9/30/2020: suppurative otitis media of children patients does not occur all the year round.
Application example 2:
liu, male, 48 years old, Haerbin, Heilongjiang province. Initial diagnosis: year 2019, 4 and 21. Suppurative otitis media recurs from the young, and the suppurative otitis media recurs for more than forty years, each time the suppurative otitis media is relieved by a certain drop of ear liquid (not detailed), the ear is covered by anti-inflammatory drugs, the suppuration and the water dripping of the right ear occur for half a month, the hearing of the sick ear is reduced, the ear canal is red and swollen, the yellow and white pus is more, and the pain is hard to endure when the ear pinna of the sick ear is pulled with little force during examination.
Prescription: xiaoyang san five spoons is externally used for ear blowing; then the sterilized dry cotton ball is tightly plugged into the external opening of the auditory canal until the next visit, and the ear canal can be taken out without air leakage; when sleeping, the left side lies on the left side, and the ear of the patient faces upward. During the period of medication, it is forbidden to dig the affected ear by itself. Pungent and pungent irritations and hair materials are contraindicated. The diagnosis is made every other day.
Four times of the above-mentioned herbs are applied one after another, five small spoons each time, the pain of the right ear is gradually relieved, but pus always flows out. During the period of administration, the patient feels that the pain part in the ear gradually moves outwards to the external auditory canal, and the local part of the right ear of the patient is still moist after checking for 4 months and 29 days in 2019. Inquiring the prescription to know that the patient is not following the medical advice, often dig out the ear canal, follow the strict word to give up, the patient only accepts, and promise to never dig out the ear canal. The three small spoons above the patient are used, and the treatment is prohibited as before, and the patient is re-diagnosed every other day.
The pain of the right ear is completely absent after the front and the back are treated by seven times of medication, and the local dryness of the right ear is checked for 5 months and 5 days, so that the right ear is healed. In 2020, 1/10, suppurative otitis media is never developed.
The following are brief records of other cure cases (excerpts):
application example 3: chen and Shi, male, 12 years old, Chongcun, swollen, rotten and purulent right ear, and the externally-blown ulcer-eliminating powder is cured for three times.
Application example 4: goldenrain, male, age 67, geontcun, swollen and rotten left ear, and the second recovery of the exterior-blown ulcer-eliminating powder.
Application example 5: chen Zhi, male, age 70, Chongcun, left ear swelling, rotting and purulence, and exterior-blown ulcer-eliminating powder for three times.
Application example 6: guo in some, male, 75 years old, Jianzhuancun, and the pain in the right ear, exopleurisy and ulcer eliminating powder are cured for ten times.
Application example 7: in case of dao-da, male, 13 years old, geongcun, swelling, rotting and purulent left ear, and secondary recovery of the external-blowing ulcer-eliminating powder.
Application example 8: guo in a certain age, male, 47 years old, Jianzhuang village, left ear itch, and external blowing ulcer-eliminating powder for three times of recovery.
Application example 9: liu Yi in certain areas, male, age 48, Chongcun people, swelling, rotting and pus discharging of the right ear, and exterior-blown ulcer-eliminating powder for three times.
Application example 10: liu Yi in certain areas, male, age 48, Chongcun people, swelling, rotting and pus discharging of the right ear, and exterior-blown ulcer-eliminating powder for three times.
Application example 11: zhou Zhi, male, 10 years old, village, pain in ears, pus discharge, exoblowing and ulcer removal powder for secondary recovery.
Application example 12: long Yi in China, female, 13 years old, Long Wang village, left ear swelling, rotting and purulence, and external blowing and ulcer eliminating powder are cured for three times.
Application example 13: chen and Shi, female, 1 year old, Chongcun, left ear swelling, rotting and purulence, and external blowing of Xiaoyang san are cured for three times.
Application example 14: wangzhi, male, 26 years old, Chongtuncun, swollen, rotten and purulent left ear, and the second recovery of the powder for external blowing and eliminating ulcer.
Application example 15: xie somebody, women, 30 years old, He Si village, left earache, itch and pus discharge, and the externally blown ulcer-eliminating powder is cured for three times.
Application example 16: chen Zhi, male, 8 years old, Chongcun, left ear swelling, rotting and purulence, and external blowing of Xiaoyang san are cured for three times.
Application example 17: wangzhi, female, 30 years old, He Si village, itching and pus on the right ear, and the second recovery of the externally blown ulcer-eliminating powder.
Application example 18: he Zhong, Man, 13 years old, He Si village, swelling, rotting and purulent of the right ear, and external-blown ulcer-eliminating powder for eight times.
Application example 19: chenzhi, male, 11 years old, Chongcun, swelling, rotting and purulent right ear, and exterior-blown ulcer-eliminating powder for secondary recovery.
Application example 20: yuan Zhi, is a Chinese medicine for curing male diseases, 57 years old, arbor village people, right ear swelling and pain, and external-blowing ulcer-eliminating powder for three times.
Application example 21: in Song Dynasty, male, age 34, Chongtuncun, swelling, rotting and purulent left ear, and external-blown ulcer-eliminating powder.
Application example 22: shaoyou, male, 10 years old, Jianzhuancun, the swelling and pain of the right ear, and the external-blown ulcer-eliminating powder can be cured once.
Application example 23: in the age of 48 years old, men in Chongcun, swelling, rotting and pus discharging in the right ear, and the externally-blown ulcer-eliminating powder is cured for three times.
Application example 24: liu Yi, male, 13 years old, Chongcun, swelling, rotting and pus discharging of the right ear, and exterior-blown ulcer-eliminating powder for three times of recovery.
Application example 25: boer Bao in certain, women, 50 years old, Jianzhuancun, swollen, rotten and purulent right ear, and the external-blown ulcer-eliminating powder is cured for three times.
Application example 26: in Song Dynasty, male, 3 months, Chongtuncun, swelling, rotting and purulent right ear, and external-blown ulcer-eliminating powder for three times.
Application example 27: li Shi, female, 48 years old, geongcun, swelling, rotting and purulent right ear, and external-blown ulcer-eliminating powder are cured for three times.
Application example 28: liu Yi, male, 47 years old, Jianzhuang village, furuncle on the right ear, and exterior-blown ulcer-eliminating powder for ten times of recovery.
Application example 29: chen and Shi, male, 8 years old, Chongcun, swollen, rotten, itching and purulent right ear, and the externally-blown ulcer-eliminating powder is cured for three times.
Application example 30: wangzhi, male, 2 years old, Chongtuncun, swelling, rotting and purulent right ear, and the second recovery of the external-blowing ulcer-eliminating powder.
The data of 852 cases of suppurative otitis media treated by the prescription are collated as follows:
775 cases are cured, symptoms are relieved, but 77 cases are still recurred, and the cure rate is 91%.
Finally, it should be noted that the above only illustrates the technical solution of the present invention, but not limited thereto, and although the present invention has been described in detail with reference to the preferred arrangement, it will be understood by those skilled in the art that modifications or equivalent substitutions may be made thereto without departing from the spirit and scope of the technical solution of the present invention.

Claims (9)

1. A traditional Chinese medicine preparation for treating suppurative otitis media is characterized in that: the traditional Chinese medicine preparation comprises the following raw materials: ramulus Oak, Olibanum, Myrrha, Borneolum Syntheticum, Borax, Catechu, and dried Alumen; the weight parts of the raw materials are as follows: 5-20 parts of oak branches, 1-10 parts of frankincense, 1-10 parts of myrrh, 1-10 parts of borneol, 1-10 parts of borax, 1-10 parts of catechu and 1-10 parts of dried alum.
2. The traditional Chinese medicine preparation for treating otitis media suppurative according to claim 1, which is characterized in that: the weight parts of the raw materials are as follows: 15-20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
3. The traditional Chinese medicine preparation for treating otitis media suppurative according to claim 2, wherein: the weight parts of the raw materials are as follows: 20 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 5 parts of borneol, 5 parts of borax, 5 parts of catechu and 5 parts of dried alum.
4. The traditional Chinese medicine preparation for treating otitis media suppurative according to claim 1, which is characterized in that: the weight parts of the raw materials are as follows: 10 parts of oak branches, 3 parts of frankincense, 3 parts of myrrh, 4 parts of borneol, 4 parts of borax, 4 parts of catechu and 4 parts of dried alum.
5. The traditional Chinese medicine preparation for treating otitis media suppurative according to claim 1, which is characterized in that: the weight parts of the raw materials are as follows: 8 parts of oak branches, 2.5 parts of frankincense, 2.5 parts of myrrh, 4 parts of borneol, 5 parts of borax, 4 parts of catechu and 5 parts of dried alum.
6. The Chinese medicinal preparation for treating otitis media suppurative according to any of claims 1-5, wherein: the Chinese medicinal preparation is in the form of powder.
7. A method of preparing a Chinese medicinal preparation for the treatment of otitis media suppurative according to any of claims 1 to 5, wherein: the preparation method comprises the following preparation steps:
a. putting the oak branches into hot sand, stir-frying, taking out when the temperature of the sand is 140-180 ℃ until the surfaces of the oak branches are scorched black, screening to remove sand, and cooling to obtain oak branch charcoal;
b. parching Olibanum and Myrrha in a pan, spraying rice vinegar, parching, and cooling to obtain Olibanum and Myrrha;
c. mixing the oak branch charcoal, the prepared frankincense, the prepared myrrh, the borneol, the borax, the catechu and the dried alum, crushing and sieving to obtain undersize powder, namely the traditional Chinese medicine preparation.
8. The method of preparing a Chinese medicinal formulation for treating otitis media suppurative according to claim 7, wherein the Chinese medicinal formulation comprises: and c, sieving by using a 120-mesh sieve.
9. The method of preparing a Chinese medicinal formulation for treating otitis media suppurative according to claim 8, wherein the Chinese medicinal formulation comprises: the temperature of the sand in step a was 150 ℃.
CN202011368890.3A 2020-11-30 2020-11-30 Traditional Chinese medicine preparation for treating suppurative otitis media and preparation method thereof Active CN112294865B (en)

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