CN112294736A

CN112294736A - Mite-removing antifungal soft film powder and production method thereof

Info

Publication number: CN112294736A
Application number: CN202011236598.6A
Authority: CN
Inventors: 徐玲花
Original assignee: Hubei Polytechnic University
Current assignee: Hubei Polytechnic University
Priority date: 2020-10-31
Filing date: 2020-10-31
Publication date: 2021-02-02

Abstract

The invention discloses mite-removing antifungal soft membrane powder and a production method thereof, wherein the preparation raw materials comprise 1-2 parts by weight of sodium alginate, 1-2 parts by weight of kaolin, 1-2 parts by weight of mung bean starch, 0.05-0.1 part by weight of trimethylglycine, 0.1-0.2 part by weight of allantoin and 3-7 parts by weight of plant essence powder; the plant essence powder is prepared from 20-40 parts of kudzu root, 30-40 parts of radix stemonae, 15-25 parts of astragalus membranaceus and 15-25 parts of cork tree bark. The product of the invention has no toxic or side effect, removes mites and fungi, repairs damaged skin cells, compacts and tenders the skin, delays skin aging, moistens the skin, whitens the skin and makes the skin look fresh and beautiful. When the plant essence powder also comprises 15-25 parts of salvia miltiorrhiza, 15-25 parts of angelica sinensis, 15-25 parts of phellodendron amurense, 15-25 parts of lycium ruthenicum, 15-30 parts of dendrobium officinale and 20-30 parts of rice bran by weight, the effect is better.

Description

Mite-removing antifungal soft film powder and production method thereof

Technical Field

The invention relates to the field of skin care products, in particular to mite-removing antifungal soft membrane powder and a production method thereof.

Background

In the fast-paced life, people have high working pressure, irregular life, insufficient sleep, environmental pollution represented by water pollution, food pollution and air pollution, daily working state facing computers, even food additives and the like, which lead to premature decline and deterioration of facial skin, and the situation becomes more and more obvious with the increase of age. Some people neglect to clean the face because the people are too busy at ordinary times, so that the skin is infected with fungi or mites, whether the fungi or the mites have great damage to the skin, the personal image can be seriously affected, the mites are taken as an example, the mites are on the face, the face has great changes, the mites suck the nutrition of skin cells, the cells are damaged, the sensory nerves of the skin are stimulated, the pruritus is caused, meanwhile, the skin cells are aged, the damage is accelerated, and the scurf is increased. For many people, deteriorated skin causes considerable confusion and even psychological shadowing for them both in social activities and in daily life. On the other hand, the social enormous development brings the continuous improvement of the living standard of the substance, and along with the improvement of the living standard of the substance of people, the health and the maintenance of the skin are more and more paid attention to people, and various skin care products such as facial masks become necessary daily necessities in the life of people.

The facial mask is a beauty skin care product applied on the face, can not only make up for the cleaning requirements which cannot be met by daily face washing, but also realize other maintenance functions of body building, face skin protection and the like on the basis of cleaning the face. Among various facial mask powders, the soft mask powder is a main variety, has a strong cleaning effect on skin after a mask body is formed, can enable the skin to be deeply cleaned, can form a film after being used, and is incomparable with common cosmetics. The current soft film powder on the market mainly comprises two types: one is composed of chemical synthetic substances and the other is composed of natural plant essences. The facial mask powder using chemical synthetic substances as main functional components has a cosmetic effect in a short time, but if the facial mask powder is used for a long time, the chemical components of the facial mask powder are easy to harm the facial skin, once the chemical components are left or absorbed by the body, the body health of a user can be influenced, some facial mask powders even contain hormones, and the skin care effect on the surface of the facial mask powder played by the chemical components is usually temporary and permanent; the Chinese herbal medicine facial mask has the characteristics of pure nature, quick action and the like, and has the functions of nursing and treating by mixing various Chinese herbal medicines beneficial to the skin, generating affinity with the skin when in use, and enabling the effective ingredients of the Chinese herbal medicines in the facial mask to permeate into the inner layer of the skin, so that the functions of improving the skin such as nutrition, removing freckles, removing acnes, whitening and the like are fundamentally exerted, and the effects of the Chinese herbal medicines can be optimized after long-term use, and the Chinese herbal medicine facial mask is safe and has no side effect.

Just because plant essence soft mask powder made of Chinese herbal medicines has many advantages and wide market prospects, more and more scientific research institutions and enterprises begin to vigorously research and develop and produce the plant essence soft mask powder, and Chinese patent CN 101536972B discloses a traditional Chinese medicine mask powder which comprises, by weight, 2-6 parts of white clove, 2-6 parts of white muscardine silkworm, 2-6 parts of bletilla striata, 2-6 parts of white pharbitis, 2-6 parts of tribulus terrestris, 2-6 parts of angelica dahurica, 2-6 parts of rhizoma typhonii, 2-6 parts of chinaroot greenbrier rhizome, 2-6 parts of angelica, 4-7 parts of ginseng, 4-7 parts of safflower carthamus, 4-7 parts of divaricate saposhnikovia root, 4-7 parts of codonopsis pilosula, 7-11 parts of phellodendron bark, 7-11 parts of white mulberry root-bark, 7-11 parts of talcum powder and 23-26 parts of loquat leaf, the facial mask powder has no toxic or side effect, can effectively remove facial spots, shrink pores, improve skin quality and enable rough and dull skin to become tender, ruddy and white and glossy. Chinese patent CN 103610635B discloses a traditional Chinese medicine combined beauty-maintaining and face-nourishing mask powder, which is prepared from 10-15 g of Chinese angelica, 20-30 g of ginseng, 10-20 g of peach blossom, 10-15 g of phellodendron bark, 15-25 g of almond, 10-15 g of astragalus root, 20-30 g of salvia miltiorrhiza, 15-25 g of white poria, 10-15 g of pearl and 10-20 g of nardostachyos according to the weight ratio. Chinese patent CN 103349636B discloses an anti-wrinkle freckle-removing herbal mask powder, which comprises, by mass, 20-28 parts of dried sea buckthorn fruits, 15-18 parts of bamboo leaves, 16-18 parts of tea leaves, 8-12 parts of aloe, 12-19 parts of orange peels and 30-35 parts of mung bean flour, and can fully supplement nutrients required by skin, promote blood circulation of the skin, enhance metabolism activity of epithelial cells of the skin, prevent wrinkles caused by premature aging of the skin, effectively remove free radicals in the skin, inhibit peroxide substances, remove generation of brown pigment in the skin and effectively remove freckles.

However, the existing plant essence soft membrane powder has limited effect or even obvious effect on the skin care effect, especially on the aspect of mite removal and fungus resistance.

Disclosure of Invention

The invention aims to solve the technical problems and provides the mite-removing and antifungal soft mask powder which integrates multiple functions of no toxic or side effect, mite removal and antifungal, damaged skin cell repair, skin tightening and tendering, skin aging delaying, skin moistening, skin whitening and the like.

In order to achieve the purpose, the invention provides mite-killing antifungal soft mask powder which is characterized by comprising the following components in parts by weight: 1-2 parts of sodium alginate, 1-2 parts of kaolin, 1-2 parts of mung bean starch, 0.05-0.1 part of trimethylglycine, 0.1-0.2 part of allantoin and 3-7 parts of plant essence powder; the plant essence powder comprises the following raw materials in parts by weight: 20-40 parts of kudzu root, 30-40 parts of radix stemonae, 15-25 parts of astragalus membranaceus and 15-25 parts of cortex berberidis.

Preferably, the plant essence powder also comprises 15-25 parts of salvia miltiorrhiza, 15-25 parts of angelica sinensis, 15-25 parts of phellodendron amurense, 15-25 parts of lycium ruthenicum, 15-30 parts of dendrobium officinale and 20-30 parts of rice bran according to parts by weight.

Further preferably, the mite-killing antifungal soft membrane powder comprises the following components in parts by weight: 1.5 parts of sodium alginate, 2 parts of kaolin, 2 parts of mung bean starch, 0.08 part of trimethyl glycine, 0.15 part of allantoin and 6 parts of plant essence powder; the plant essence powder comprises the following raw materials in parts by weight: 30 parts of kudzuvine root, 35 parts of sessile stemona root, 20 parts of membranous milkvetch root, 20 parts of cortex berberidis, 20 parts of danshen root, 20 parts of Chinese angelica, 18 parts of amur corktree bark, 18 parts of black medlar, 25 parts of dendrobium officinale and 25 parts of rice bran.

Another object of the present invention is to provide a production method for producing the mite-killing antifungal soft membrane powder. In order to realize the purpose, the production method of the mite-killing antifungal soft membrane powder provided by the invention comprises the following steps:

(1) preparing the plant essence powder: weighing the components of the preparation raw materials of the plant essence powder according to the parts by weight, adding the components into a stainless steel tank, adding 600-1000 parts by weight of deionized water and 15-20 parts by weight of ethanol, soaking for 0.5-1 hour, heating to boil, maintaining boiling for 1-2 hours, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 500-800 parts by weight of deionized water and 5-10 parts by weight of ethanol into filter residues, heating to boil, maintaining boiling for 0.5-1 hour, and filtering with 600 meshes to obtain filtrate II; mixing the filtrate I and the filtrate II, recovering ethanol, drying the filtrate to obtain a solid, crushing the solid, and sieving the crushed solid with a 200-300-mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: and (3) taking dried sodium alginate, kaolin, mung bean starch, trimethylglycine and allantoin which are sieved by a sieve of 200-600 meshes according to the weight parts, uniformly mixing the dried sodium alginate, the kaolin, the mung bean starch, the trimethylglycine and the allantoin with the plant essence powder according to the weight parts, sterilizing and packaging to obtain the finished product of the mite-removing antifungal soft mask powder.

The active ingredients contained in the kudzuvine root can reduce the formation of melanin in skin cells, is beneficial to whitening the skin, enables the skin color to be more uniform, tender and plump, and can inhibit bacteria, resist inflammation, resist oxidation and delay skin aging.

Radix Stemonae can prevent corrosion, kill bacteria, and kill mite, and can make skin smooth and healthy.

The astragalus membranaceus can improve cell vitality, enhance skin immunity and delay skin aging, and the astragalus membranaceus is added into the product to enable the skin to be smooth and fine.

The effective components contained in the cortex berberidis can not only resist bacteria and diminish inflammation, but also reduce the secretion of skin cell grease, so that the skin is fine, smooth and clean.

The active ingredients of the salvia miltiorrhiza have strong bacteriostatic action, and when the active ingredients are matched with the radix puerariae, the active ingredients have better synergistic effect in the aspects of resisting bacteria and diminishing inflammation, protecting skin cells, promoting the regeneration of damaged cells and the like.

The angelica extract is added into the soft film powder and applied on face, which can effectively kill acarid, prevent facial dryness and pruritus and avoid or relieve skin melanin.

The cortex Phellodendri extract can be added into soft film powder for applying face to effectively resist fungi, solve the problems of facial acne and pruritus, and maintain skin health.

The Lycium ruthenicum Murr extract can act on skin to increase blood circulation of facial skin, help to keep luster, resist oxidation, effectively delay skin aging, and maintain young state.

The dendrobium officinale has a very good moisturizing effect, and the extract of the dendrobium officinale can help skin to be moisturized and moisturized, resist radiation and the like. Particularly, when the dendrobium officinale and the kudzuvine root are combined, the synergistic effect is achieved in the aspects of resisting skin oxidation, delaying skin aging and the like.

The testa oryzae extract can make skin wrinkle-resisting and tender; when the rice bran and the cortex tilleri are combined, the effects of obviously enhancing the antibacterial and anti-inflammatory effects of the cortex tilleri, reducing the secretion of skin oil and enabling the skin to be fine, smooth and clean can be achieved.

The beneficial effects of the invention at least comprise: has no toxic and side effects, removes mites and fungi, repairs damaged skin cells, compacts and tenders the skin, delays skin aging, moistens the skin, whitens the skin and makes the skin look fresh.

Detailed Description

The present invention will be described in further detail by way of examples. It should be understood that the following examples are only illustrative of the present invention and are not intended to limit the scope of the present invention. It is intended that all modifications or alterations to the steps or conditions of the present invention be made without departing from the spirit or essential characteristics thereof.

Unless otherwise specified, the technical means used in the examples are conventional means well known to those skilled in the art.

Example 1

(1) Preparing the plant essence powder: weighing 20kg of kudzuvine root, 30kg of sessile stemona root, 25kg of membranous milkvetch root and 15kg of cork tree bark with the water content not more than 9 percent, adding the materials into a stainless steel tank, adding 1000kg of deionized water and 15kg of ethanol, soaking for 0.5 hour, heating to boil, keeping boiling for 1 hour, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 800kg of deionized water and 5kg of ethanol into the filter residue, heating to boil, maintaining boiling for 1 hour, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrates I and II, recovering ethanol, concentrating under reduced pressure at 40 deg.C under-0.1 MPa, vacuum drying to obtain solid, pulverizing the solid, and sieving with 200 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing 1kg of sodium alginate with the water content of not more than 10 percent and passing through a 200-mesh sieve, 2kg of kaolin, 1kg of mung bean starch, 0.1kg of trimethylglycine and 0.1kg of allantoin, uniformly mixing with 3kg of plant essence powder, sterilizing and packaging to obtain the finished product of the mite-killing antifungal soft mask powder.

Example 2

(1) Preparing the plant essence powder: weighing 20kg of kudzuvine root, 20kg of sessile stemona root, 7.5kg of astragalus and 12.5kg of cork tree bark with the water content not more than 9 percent, adding the materials into a stainless steel tank, adding 300kg of deionized water and 10kg of ethanol, soaking for 1 hour, heating to boil, maintaining the boiling for 2 hours, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 250kg of deionized water and 5kg of ethanol into the filter residue, heating to boil, maintaining boiling for 0.5 h, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrates I and II, recovering ethanol, concentrating under reduced pressure at 45 deg.C under-0.1 MPa, vacuum drying to obtain solid, pulverizing the solid, and sieving with 300 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing sodium alginate, kaolin, mung bean starch, trimethylglycine, 0.5kg of allantoin sodium alginate, 0.25kg of kaolin, 0.5kg of mung bean starch, 0.0125kg of trimethylglycine and 0.05kg of allantoin which have the water content of not more than 10 percent and are sieved by a 600-mesh sieve, uniformly mixing with 1.75kg of plant essence powder, sterilizing and packaging to obtain the finished product of the mite-removing antifungal soft membrane powder.

Example 3

(1) Preparing the plant essence powder: weighing 10kg of kudzuvine root with the water content not more than 9%, 15kg of sessile stemona root, 12.5kg of astragalus root, 7.5kg of cork tree bark, 12.5kg of salvia miltiorrhiza, 7.5kg of angelica, 7.5kg of amur corktree bark, 7.5kg of black Chinese wolfberry, 15kg of dendrobium officinale and 10kg of rice bran, adding the materials into a stainless steel tank, adding 500kg of deionized water and 7.5kg of ethanol, soaking for 0.5 hour, heating to boil, keeping boiling for 1 hour, and filtering by 600 meshes to obtain filtrate I and filter residue; adding 400kg of deionized water and 2.5kg of ethanol into the filter residue, heating to boil, maintaining boiling for 1 hour, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrate I and the filtrate II, recovering ethanol, concentrating the filtrate under-0.1 MPa at 45 deg.C under reduced pressure, vacuum drying to obtain solid, pulverizing the solid, and sieving with 200 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing 1kg of sodium alginate with the water content of not more than 10 percent and passing through a 200-mesh sieve, 2kg of kaolin, 1kg of mung bean starch, 0.1kg of trimethylglycine, 0.1kg of allantoin and 3kg of plant essence powder, uniformly mixing, sterilizing and packaging to obtain the finished product of the mite-killing antifungal soft mask powder.

Example 4

(1) Preparing the plant essence powder: weighing 40kg of kudzuvine root with the water content not more than 9%, 40kg of sessile stemona root, 15kg of astragalus root, 25kg of cork tree bark, 15kg of salvia miltiorrhiza, 25kg of angelica, 25kg of amur corktree bark, 25kg of black medlar, 15kg of dendrobium officinale and 30kg of rice bran, adding the materials into a stainless steel tank, adding 600kg of deionized water and 20kg of ethanol, soaking for 1 hour, heating to boil, keeping boiling for 2 hours, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 500kg of deionized water and 10kg of ethanol into the filter residue, heating to boil, maintaining boiling for 0.5 hour, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrate I and the filtrate II, recovering ethanol, concentrating the filtrate under-0.1 MPa at 50 deg.C under reduced pressure, vacuum drying to obtain solid, pulverizing the solid, and sieving with 300 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing 2kg of sodium alginate with the water content of not more than 10 percent and passing through a 600-mesh sieve, 1kg of kaolin, 2kg of mung bean starch, 0.05kg of trimethylglycine, 0.2kg of allantoin and 7kg of plant essence powder, uniformly mixing, sterilizing and packaging to obtain the finished product of the mite-removing antifungal soft mask powder.

Example 5

(1) Preparing the plant essence powder: weighing 14kg of kudzuvine root with the water content not more than 9%, 15kg of sessile stemona root, 9kg of astragalus root, 9kg of cork tree bark, 9kg of salvia miltiorrhiza, 11kg of angelica, 9kg of amur corktree bark, 7.5kg of black medlar, 10kg of dendrobium officinale and 11kg of rice bran, adding the materials into a stainless steel tank, adding 350kg of deionized water and 8kg of ethanol, soaking for 1 hour, heating to boil, keeping boiling for 1 hour, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 300kg of deionized water and 3kg of ethanol into the filter residue, heating to boil, maintaining boiling for 0.5 h, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrate I and the filtrate II, recovering ethanol, concentrating the filtrate under-0.1 MPa at 50 deg.C under reduced pressure, vacuum drying to obtain solid, pulverizing the solid, and sieving with 200 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing 1.2kg of sodium alginate with the water content of not more than 10 percent and passing through a 200-mesh sieve, 1.2kg of kaolin, 2kg of mung bean starch, 0.1kg of trimethyl glycine, 0.15kg of allantoin and 4kg of plant essence powder, uniformly mixing, sterilizing and packaging to obtain the finished product of the mite-killing antifungal soft mask powder.

Example 6

(1) Preparing the plant essence powder: weighing 30kg of kudzuvine root with the water content not more than 9%, 35kg of sessile stemona root, 20kg of astragalus root, 20kg of cork tree bark, 20kg of salvia miltiorrhiza, 20kg of angelica, 18kg of amur corktree bark, 18kg of black medlar, 25kg of dendrobium officinale and 25kg of rice bran, adding the materials into a stainless steel tank, adding 800kg of deionized water and 15kg of ethanol, soaking for 1 hour, heating to boil, keeping boiling for 1 hour, and filtering with 600 meshes to obtain filtrate I and filter residue; adding 600kg of deionized water and 6kg of ethanol into the filter residue, heating to boil, maintaining boiling for 0.5 h, and filtering with 600 meshes to obtain a filtrate II; mixing the filtrate I and the filtrate II, recovering ethanol, concentrating the filtrate under-0.1 MPa at 45 deg.C under reduced pressure, vacuum drying to obtain solid, pulverizing the solid, and sieving with 300 mesh sieve to obtain plant essence powder;

(2) preparing a finished product of the mite-killing antifungal soft film powder: weighing 1.5kg of sodium alginate with the water content of not more than 10 percent and passing through a 300-mesh sieve, 2kg of kaolin, 2kg of mung bean starch, 0.08kg of trimethyl glycine, 0.15kg of allantoin and 6kg of plant essence powder, uniformly mixing, sterilizing and packaging to obtain the finished product of the mite-killing antifungal soft mask powder.

Example 7 skin irritation, allergy and toxicity test

42 healthy mice with the weight of 20-25 g are taken and randomly divided into 6 groups, and 7 mice in each group. Approximately 1cm by 2cm of area was shaved from both sides of the dorsal spine of each mouse 2h prior to the experiment, without damaging the skin.

The mite-killing antifungal soft mask powders prepared in examples 1 to 6 were respectively mixed with warm water just before being applied to the face, and used for testing 1 group of mice. During the test, 0.4g of the uniformly mixed mite-killing antifungal soft membrane powder is uniformly coated on the skin of a mouse hair shaving area, the skin is covered by two layers of gauze, the gauze is fixed by using medical adhesive plaster and is kept for 30 hours, the gauze is uncovered for observation once in the period of 4h, 10h and 20h, no irritation or anaphylactic reaction occurs, the mite-killing antifungal soft membrane powder is washed away by warm water when the time reaches 30h, no irritation or anaphylactic reaction occurs, and then the observation is performed once every 24h for one week. In a week observation period, the skin, hair, eyes, mucosa, respiratory system, central nervous system, limbs and other parts of the mouse have no toxic manifestation, the mouse can move freely, and no abnormality in mental state, appetite and defecation occurs, and the mouse does not die. This example demonstrates that the mite-killing antifungal soft mask powder provided by the invention is safe when applied to the skin.

Comparative example 1: the kind, weight parts and preparation method of the raw material components of the comparative example soft membrane powder are the same as those of example 6 except that the raw material components do not contain salvia miltiorrhiza, dendrobium officinale, rice bran and cork tree bark, except that water and ethanol added in the preparation process are also reduced according to the reduction ratio of the weight parts of the raw material components.

Comparative example 2: the kind, weight parts and preparation method of the soft membrane powder of this comparative example were the same as those of example 6 except that the raw material components did not contain puerariae radix, rice bran and cork tree bark, except that water and ethanol added during the preparation process were also reduced in accordance with the reduction ratio of the weight parts of the raw material components.

Comparative example 3: the kind, weight parts and preparation method of the soft membrane powder of this comparative example were the same as those of example 6 except that the raw material components did not contain rice bran and cork tree bark, except that water and ethanol added during the preparation process were also reduced in the reduction ratio of the weight parts of the raw material components.

Comparative example 4: the kind, weight parts and preparation method of the raw material components of the comparative example soft membrane powder are the same as those of example 6 except that the raw material components do not contain kudzu root, salvia miltiorrhiza, dendrobium officinale and rice bran, except that water and ethanol added in the preparation process are also reduced according to the reduction ratio of the weight parts of the raw material components.

Comparative example 5: the kind, weight parts and preparation method of the other raw material components are the same as those of example 6 except that the raw material components do not contain kudzu root, red sage root, dendrobium officinale and cork tree bark, except that the water and ethanol added in the preparation process are also reduced according to the reduction ratio of the weight parts of the raw material components.

Comparative example 6: the kind, weight parts and preparation method of the other raw material components are the same as those of the example 6 except that the raw material components do not contain the root of kudzu vine, the root of red-rooted salvia and the dendrobium officinale, except that the water and the ethanol added in the preparation process are also reduced according to the reduction ratio of the weight parts of the raw material components.

Comparative example 7: the comparative example soft film powder is a certain brand of commercially available antibacterial and anti-inflammatory soft film powder.

Comparative example 8: the comparative example soft film powder is oil-control soft film powder of a certain brand sold in the market.

Comparative example 9: the comparative example film powder is a commercially available nursing film powder of a certain brand.

Comparative example 10: the comparative example soft mask powder is a commercial soft mask powder with mite removing and antifungal functions of a certain brand.

Example 8 comparison of bacteriostatic Effect

The Minimum Inhibitory Concentration (MIC) determination method is adopted to determine the inhibitory effect, and then comparison is carried out, wherein the smaller the MIC value is, the stronger the inhibitory capacity is.

Respectively preparing suspensions of malassezia furfur (easy to cause malassezia skin diseases), microsporum canis and candida albicans with normal saline, diluting to turbidity not lower than 2.0McF, diluting with normal saline 100 times, and diluting with RPMI 1640 10 times; and preparing various soft membrane powders into uniform suspension by a homogenizer, slightly shaking and culturing for 72-96 h in a 96-hole culture plate by adopting a two-time dilution method, carrying out color comparison at 490nm, and calculating MIC. The results are shown in Table 1.

TABLE 1 MIC concentrations (mg/ml) of various soft film powders for different bacteria

As can be seen from table 1, the anti-bacterial effect of the soft membrane powder containing the kudzu root, the red sage root and the dendrobium officinale in the raw materials is obviously better than that of the soft membrane powder containing the kudzu root in the raw materials and that of the soft membrane powder containing the red sage root and the dendrobium officinale in the raw materials, which shows that the effective components of the kudzu root, the red sage root and the dendrobium officinale play a role in synergy for the sterilization and anti-bacterial effects of the soft membrane powder; the preparation raw materials simultaneously contain the soft membrane powder of the cork tree bark and the rice bran, and the antibacterial effect of the soft membrane powder is obviously better than that of the soft membrane powder only containing the cork tree bark in the preparation raw materials and that of the soft membrane powder only containing the rice bran in the preparation raw materials, so that the effective ingredients of the cork tree bark and the rice bran play a synergistic effect on the antibacterial and bacteriostatic effects of the soft membrane powder. As can be seen from the table 1, the anti-mite and anti-fungus soft mask powder has obviously better antibacterial effect than the commercially available antibacterial and anti-inflammatory soft mask powder of a certain brand.

Example 9 oil control Effect experiment

105 volunteers with more oil secretion on cheeks are selected, male and female are unlimited, the age is 20-42 years old, the volunteers are randomly divided into 3 groups, and 35 volunteers are selected. The volunteers waited for 30min after washing the face, and then used different soft mask powders on the left and right cheeks of each volunteer, two kinds for each person, the soft mask powder of comparative example 8 and the soft mask powder of example 6 were not used for the same volunteer, the same two kinds were used for the same group of volunteers, and the usage and the dosage of each soft mask powder were performed according to daily usage. The skin oil secretion of the left and right cheeks was measured before (0h) and 2h, 4h, 8h, and 10h after the application of the soft mask powder using a skin oil tester (Sebumeter, Courage + Khazaka SM815, germany), and the average value of the results of the test using the same soft mask powder was calculated. The test results are shown in Table 2.

TABLE 2 skin oil secretion (. mu.g/cm)²) Test results

	0h	2h	4h	8h	10h
						Comparative example 4	26.8	40.1	38.7	39.2	41.4
Comparative example 5	27.2	40.1	39.6	37.7	35.9
						Comparative example 6	26.4	38.8	26.6	20.8	17.5
Comparative example 8	27.1	39.8	39.0	38.5	41.2
						Example 6	26.9	35.4	28.2	21.0	17.2

As can be seen from the data in Table 2, the skin oil secretion of each kind of the soft membrane powder is increased within the first 2h, which is caused by the fact that the oil secretion rule of the skin and the effect of the soft membrane powder are not shown; after the 4h, the soft membrane powder containing the tiller skin and the rice bran in the raw materials is prepared, so that the effect of inhibiting the secretion of skin oil is obviously stronger than that of the soft membrane powder only containing the tiller skin in the raw materials and that of the soft membrane powder only containing the rice bran in the raw materials, and the effect that the effective ingredients of the tiller skin and the rice bran play a synergistic role in inhibiting the secretion of skin oil of the soft membrane powder is shown; as can be seen from the table 2, the effect of the mite-killing antifungal soft mask powder for inhibiting the secretion of skin grease is obviously better than that of the commercially available oil-controlling soft mask powder of a certain brand, which is reflected from the 4 th hour later; also, the soft film powder of example 6 of the present invention can cause the skin oil secretion amount to be continuously decreased within 10 hours, as in comparative example 6.

The volunteers who used the film powder of comparative example 8 and the film powder of example 6 were allowed to go home and continue to use the two film powders, respectively, once every day, morning and evening, 15 minutes each time, and a follow-up visit every 10 days, the amount of oil secretion of the skin on the face was measured (the film powder was not used within 18 hours before the measurement was guaranteed), the average value was calculated, and the follow-up visit was continued for 30 days, and the test results are shown in table 3.

TABLE 3 follow-up test of skin oil secretion (. mu.g/cm)²) Results

As can be seen from Table 3, the acarid-removing antifungal soft membrane powder of example 6 of the invention can continuously reduce the skin oil secretion within 30 days, and the effect is obviously better than that of a certain brand of oil-controlling soft membrane powder sold on the market.

Example 10 hydroxyl radical scavenging electron paramagnetic resonance spectrometer detection of the invention

0.5ml of phosphate buffer solution with pH value of 7.4, 5. mu.L of 5, 5-dimethyl-1-pyrroline-N-oxide, 250. mu.L of 0.1M H were added to the test tube in this order at room temperature₂O₂1.5ml of 0.5mM homogeneous suspension or blank of the film powder described in comparative examples 1, 2, 3, 9, example 6, 250. mu.L of 3mM FeSO₄The solution was injected into a quartz capillary after 6 minutes for electron paramagnetic resonance detection, and the results are shown in Table 4.

TABLE 4 clearance of hydroxyl radicals

The data in table 4 show that the soft film powder containing radix puerariae, radix salviae miltiorrhizae and dendrobium officinale in the preparation raw materials has a very obviously higher clearance rate for hydroxyl free radicals than the soft film powder containing only radix puerariae in the preparation raw materials and the soft film powder containing only radix salviae miltiorrhizae and dendrobium officinale in the preparation raw materials, and the effective components of the radix puerariae, the radix salviae miltiorrhizae and the dendrobium officinale have a synergistic effect on the effect of eliminating the hydroxyl free radicals of the soft film powder. The clearance rate of hydroxyl free radicals in the embodiment 6 of the invention reaches 93 percent, which shows that the soft membrane powder has strong skin oxidation resistance.

Example 11 mite-inhibiting effect of the present invention

Selecting 40 test subjects who voluntarily receive the test subjects, wherein the test subjects have unlimited characters and age of 21-50 years, cleaning the face, scraping off sebum on two sides of the nasal alar part respectively by using a clean toothpick, respectively and uniformly coating the sebum on the counting chamber part of a blood counting chamber of a blood counting plate on which normal saline is dripped, respectively counting the number of live mites on the left and right nasal alar parts of the test subjects in unit visual field by using a mite detector (Ruihoge, model RH-MDI), and taking an average value; then, the number of live mites on the left and right alar regions of a subject who received two kinds of the soft membrane powders in a unit visual field were counted by the above method after using the soft membrane powder of example 6 of the present invention for 15 minutes on the left face and the soft membrane powder of comparative example 10 on the right face for 15 minutes, and the average value was calculated, and the mite inhibition rate (number of live mites before using soft membrane powder-number of live mites after using soft membrane powder)/number of live mites before using soft membrane powder) was calculated and the results are shown in table 5.

TABLE 5 comparison of mite-inhibiting rates of the powder of the pia

As can be seen from the data in Table 5, the mite inhibiting rate of the soft mask powder of example 6 of the invention is 89.1%, which is obviously higher than 74.6% of the mite inhibiting rate of the soft mask powder of comparative example 10.

The invention has statistical use effect:

98 volunteered test populations were selected, with unlimited gender, ages 20-41 years, 86 of which were greasy on the facial skin and 50 of which had inflammation on the face. The test population was randomly divided into two groups of 49 individuals each containing 43 individuals with greasy facial skin and 25 individuals with inflammation on the face. One group of the soft film powder described in comparative example 10 was used for 15 minutes each time every morning and evening, and the other group of the soft film powder described in example 6 of the present invention was used for 15 minutes each time every morning and evening, and the score was counted after 1 month, and the score criteria were: the score of 5 is very satisfactory, the score of 3 is satisfactory, the score of 1 is general, and the score of 0 is unsatisfactory. The results are shown in Table 6.

Table 6 usage effect scoring

It should be noted that, in the group using comparative example 10, 14 of 25 persons with facial inflammation completely disappeared, 8 persons significantly improved, and 3 persons did not improve. In the group using example 6 of the present invention, 22 out of 25 persons with facial inflammation completely disappeared, and the rest 3 persons had significant improvement in inflammation. From the statistical data and the data in table 6, it can be seen that the using effect of the soft membrane powder of example 6 of the invention is obviously better than that of the commercially available soft membrane powder with mite-killing and antifungal functions of a certain brand in many aspects.

Several typical effects of the invention are as follows:

1. according to the introduction of a person, after a certain lithocarpus person cleans the face in the morning and at night every day, the mite-removing antifungal soft membrane powder disclosed by the embodiment 6 of the invention is uniformly mixed with warm water and applied to the face, the symptom of fungal infection disappears after one week every time for 20 minutes, and the skin of the face returns to be normal; after one month, the face becomes smooth and glossy, the skin color is white, bright red and the fine wrinkles are obviously reduced.

2. When a woman worried about a certain age, the face of the woman is 32 years old and the face appears mite infection symptom before one week, the skin becomes rough, a small amount of skin is peeled off, pores are enlarged, and the nose becomes red. By introduction, after cleaning the face of a certain worship every morning and evening, the mite-killing antifungal soft membrane powder disclosed by the embodiment 5 of the invention is uniformly mixed with warm water and is applied to the face, and after 20 minutes each time and a week, the mite infection symptom disappears; after half a month, the skin color begins to become uniform, glossy and ruddy.

3. After a certain land is introduced, a man is 23 years old and feels that the face is scorched and red before 10 days, the face has mite spots, and after the certain land is cleaned in the morning and evening every day, warm water is used for uniformly mixing the mite removing and antifungal soft membrane powder disclosed by the embodiment 6 of the invention and is applied to the face, 20 minutes each time, and after 10 days, the mite infection symptom disappears; after the household advice, the facial skin becomes firm, tender, smooth and moist after the continuous use for nearly one month.

4. In the age of 22 years old in female, mite infection symptoms appear on the face half a month before the female feels greasy on the face, the skin becomes black and rough, pores gradually become larger, and blackheads appear around the nasal wings. By introduction, after a certain day of the Korea is cleaned in the morning and evening, the acarus-killing antifungal soft mask powder disclosed by the embodiment 4 of the invention is uniformly mixed with warm water and is applied to the face, and the symptoms are obviously improved after one week every 20 minutes; after half a month, the mite infection symptom disappears, and the complexion becomes fine, smooth, ruddy and glossy; after the mask is continuously used for half a month, the skin of the face feels tight and smooth, and the effect of the mask on the product is very satisfactory.

Claims

1. The mite-removing antifungal soft film powder is characterized by comprising the following components in parts by weight: 1-2 parts of sodium alginate, 1-2 parts of kaolin, 1-2 parts of mung bean starch, 0.05-0.1 part of trimethylglycine, 0.1-0.2 part of allantoin and 3-7 parts of plant essence powder;

the plant essence powder comprises the following raw materials in parts by weight: 20-40 parts of kudzu root, 30-40 parts of radix stemonae, 15-25 parts of astragalus membranaceus and 15-25 parts of cortex berberidis.

2. The acarus-killing antifungal soft film powder as claimed in claim 1, wherein: the plant essence powder also comprises 15-25 parts of salvia miltiorrhiza, 15-25 parts of angelica sinensis, 15-25 parts of phellodendron amurense, 15-25 parts of lycium ruthenicum, 15-30 parts of dendrobium officinale and 20-30 parts of rice bran according to parts by weight.

3. The acarus-killing antifungal soft membrane powder as claimed in claim 2, which is characterized by comprising the following components in parts by weight: 1.5 parts of sodium alginate, 2 parts of kaolin, 2 parts of mung bean starch, 0.08 part of trimethyl glycine, 0.15 part of allantoin and 6 parts of plant essence powder;

the plant essence powder comprises the following raw materials in parts by weight: 30 parts of kudzuvine root, 35 parts of sessile stemona root, 20 parts of membranous milkvetch root, 20 parts of cortex berberidis, 20 parts of danshen root, 20 parts of Chinese angelica, 18 parts of amur corktree bark, 18 parts of black medlar, 25 parts of dendrobium officinale and 25 parts of rice bran.

4. A method for producing the mite-killing antifungal soft film powder as claimed in any one of claims 1 to 3, which comprises the steps of: