CN112147186B - Specific protein analysis method and control device based on blood cell analyzer - Google Patents
Specific protein analysis method and control device based on blood cell analyzer Download PDFInfo
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- CN112147186B CN112147186B CN202011007592.1A CN202011007592A CN112147186B CN 112147186 B CN112147186 B CN 112147186B CN 202011007592 A CN202011007592 A CN 202011007592A CN 112147186 B CN112147186 B CN 112147186B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
Abstract
The invention discloses a specific protein analysis method and a control device based on a blood cell analyzer, wherein the method comprises the following steps: according to a specific protein analysis instruction input by a user, detecting the refraction voltage of the diluent in the reaction cup, and injecting a tested blood sample into the reaction cup to perform at least one specific protein analysis; when the difference value between the refraction voltage of the diluent and the reference voltage exceeds a set threshold value, cleaning the reaction cup after the analysis of the blood sample to be tested is finished, and updating the reference voltage to be the refraction voltage of the diluent in the reaction cup after the cleaning of the reaction cup is finished. Because the relation between the refractive voltage of the diluent in the reaction cup and the difference value of the reference voltage and the set threshold is detected, whether the reaction cup trigger instruction is sent to clean the reaction cup is judged, so that the reaction cup does not need to be cleaned after the analysis of the blood sample to be tested is finished each time, the cleaning times are reduced, and the detection time is saved.
Description
Technical Field
The invention relates to the technical field of blood cell analyzers, in particular to a specific protein analysis method and a control device based on a blood cell analyzer.
Background
Blood cell analyzers are used for various analyses of blood components, such as technical and differential detection of leukocytes in blood, detection of hemoglobin concentration in erythrocytes, and analytical detection of specific proteins in blood. Specific protein analysis is mainly to detect specific functional proteins in blood, such as immunoglobulins, etc., to understand the performance of various aspects of the body.
When analyzing specific proteins, the blood cell analyzer injects the tested blood sample into the reaction cup, then analyzes different specific proteins in the tested blood sample by injecting different reagents, after the analysis is completed, the reaction liquid in the reaction cup is discharged from the liquid outlet, the diluent is injected into the reaction cup to wait for the analysis of the next tested blood sample, and when the tested blood sample is not injected into the reaction cup, the diluent is required to be injected into the reaction cup to prevent external air from entering the reaction cup. In order to prevent the reaction solution of the previous blood sample to be tested from remaining in the cuvette, the cuvette needs to be cleaned because of interference with the analysis of the subsequent blood sample to be tested.
The existing blood cell analyzer generally adopts a mode that a cleaning command is triggered to clean a reaction cup after specific protein analysis is completed on one tested blood sample at a time to clean the reaction cup. Thus, the number of times of washing is large, the amount of cleaning liquid consumed for washing is excessive, the detection cost is increased, and the time for detecting a specific protein in a blood sample at a time is prolonged due to the long time consumed for washing.
Disclosure of Invention
The invention aims to provide a specific protein analysis method and a control device based on a blood cell analyzer, which avoid cleaning a specific protein reaction cup after each detection.
According to a first aspect, there is provided in one embodiment a method of protein-specific analysis based on a blood cell analyzer including a cuvette for performing protein-specific analysis on a blood sample to be tested, and a cleaning device for cleaning the cuvette, the method comprising:
receiving a specific protein analysis instruction input by a user;
detecting the refraction voltage of the diluent in the reaction cup according to the specific protein analysis instruction input by the user, and injecting the tested blood sample into the reaction cup for at least one specific protein analysis;
acquiring a reference voltage;
when detecting that the difference value between the refraction voltage of the diluent and the reference voltage exceeds a set threshold value, sending a reaction cup cleaning trigger instruction to the cleaning device so as to clean the reaction cup after the analysis of the blood sample to be tested is finished, and updating the reference voltage to be the refraction voltage of the diluent in the reaction cup when the reaction cup is finished after the cleaning of the reaction cup.
According to a second aspect, there is provided in one embodiment a specific protein analysis control apparatus based on a blood cell analyzer including a cuvette for performing a specific protein analysis on a blood sample to be measured, and a cleaning device for cleaning the cuvette, the control apparatus comprising:
the receiving instruction unit is used for receiving a specific protein analysis instruction input by a user;
a specific protein analysis unit for detecting the refraction voltage of the diluent in the reaction cup according to the specific protein analysis instruction input by the user, and injecting the detected blood sample into the reaction cup for at least one specific protein analysis;
the reference voltage acquisition unit is used for acquiring a reference voltage;
and the cleaning triggering unit is used for sending a reaction cup cleaning triggering instruction to the cleaning device when detecting that the difference value between the refraction voltage of the diluent and the reference voltage exceeds a set threshold value so as to clean the reaction cup after the analysis of the blood sample to be tested is finished, and updating the reference voltage to the refraction voltage of the diluent in the reaction cup when the reaction cup is finished after the cleaning of the reaction cup is finished.
According to the specific protein analysis method and the control device based on the blood cell analyzer, the relation between the refractive voltage of the diluent in the reaction cup and the difference value of the reference voltage and the set threshold value is detected, so that whether the reaction cup is sent to be triggered to be cleaned is judged, the reaction cup does not need to be cleaned after the analysis of the blood sample to be detected is finished, the cleaning times are reduced, and the detection time is saved.
Drawings
FIG. 1 is a block diagram of a specific protein analysis channel in a blood cell analyzer;
FIG. 2 is a flow chart of a specific protein analysis method based on a blood cell analyzer according to one embodiment;
FIG. 3 is a flow chart of another embodiment of a method for analyzing a specific protein based on a blood cell analyzer;
FIG. 4 is a block diagram showing the structure of a specific protein analysis control apparatus according to an embodiment;
FIG. 5 is a block diagram showing a specific protein analysis control apparatus according to another embodiment.
Detailed Description
The invention will be described in further detail below with reference to the drawings by means of specific embodiments. Wherein like elements in different embodiments are numbered alike in association. In the following embodiments, numerous specific details are set forth in order to provide a better understanding of the present application. However, one skilled in the art will readily recognize that some of the features may be omitted, or replaced by other elements, materials, or methods in different situations. In some instances, some operations associated with the present application have not been shown or described in the specification to avoid obscuring the core portions of the present application, and may not be necessary for a person skilled in the art to describe in detail the relevant operations based on the description herein and the general knowledge of one skilled in the art.
Furthermore, the described features, operations, or characteristics of the description may be combined in any suitable manner in various embodiments. Also, various steps or acts in the method descriptions may be interchanged or modified in a manner apparent to those of ordinary skill in the art. Thus, the various orders in the description and drawings are for clarity of description of only certain embodiments, and are not meant to be required orders unless otherwise indicated.
The numbering of the components itself, e.g. "first", "second", etc., is used herein merely to distinguish between the described objects and does not have any sequential or technical meaning. The terms "coupled" and "connected," as used herein, are intended to encompass both direct and indirect coupling (coupling), unless otherwise indicated.
In order to solve the problem that the reaction cup needs to be cleaned every time the blood cell analyzer performs specific protein analysis, a fixed and invariable reference voltage can be set, the refractive voltage in the reaction cup is usually used as the reference voltage when the blood cell analyzer is just started, whether the difference value between the current refractive voltage of the diluent in the reaction cup and the reference voltage exceeds a set threshold value is detected every time the specific protein analysis is performed subsequently, if the difference value exceeds the set threshold value, a reaction cup cleaning trigger instruction is sent to clean the reaction cup, however, as the temperature of the diluent when the blood cell analyzer is just started, the batch and the temperature and the batch of the diluent during subsequent detection may be different, the refractive index corresponding to the refractive voltage of the diluent is changed, and the difference value between the current refractive voltage of the diluent and the reference voltage during the subsequent detection always exceeds the set threshold value, so that the blood cell analyzer is cleaned and is in dead circulation.
In the embodiment of the invention, the reference voltage is updated after the reaction cup is cleaned each time, and the refraction voltage of the diluent in the cleaned reaction cup is used as the reference voltage, so that the reference voltage is different after the reaction cup is cleaned each time, and the situation that the temperature of the diluent, the batch and the temperature of the diluent in the follow-up detection are possibly different when the blood cell analyzer is just started is avoided.
In summary, the blood cell analyzer of the embodiment of the present invention includes a set of specific protein analysis channels for performing at least one function of a blood sample to be tested, please refer to fig. 1, the specific protein analysis channels include a reaction cup 20 for performing a specific protein analysis of the blood sample to be tested, a washing device 30 for washing the reaction cup, a diluent injection device 50 for injecting a diluent into the reaction cup 20, a sample injection device 50 for injecting a reagent for analyzing the blood sample to be tested, a reagent injection device 60 for injecting a reagent for analyzing the specific protein, a liquid discharge device 70 for discharging a liquid in the reaction cup 20, and a control device 10 for controlling the washing device 30, the diluent injection device 40, the sample injection device 50, the reagent injection device 60 and the liquid discharge device 70, the control device 10 is used for controlling an analysis and detection of the specific protein, and referring to fig. 2, fig. 2 is a flowchart of a specific protein analysis method based on the blood cell analyzer of an embodiment, the method includes steps S101 to S104, and is described below.
Step S101, receiving a specific protein analysis instruction input by a user. When a specific protein analysis is required for a new blood sample to be tested, the inspector performs a related operation on the blood cell analyzer, so that the control device receives a specific protein analysis instruction for input.
Step S102, according to the specific protein analysis instruction input by the user, the refraction voltage of the diluent in the reaction cup 20 is detected, and the detected blood sample is injected into the reaction cup 20 for at least one specific protein analysis.
After receiving the specific protein analysis instruction, the control device 10 controls the blood sample to be tested to be injected into the reaction cup 20 through the sample injection device 50, and before the blood sample to be tested is injected into the reaction cup 20, the control device 10 also needs to collect the refraction voltage of the diluent in the reaction cup 20 at the same time, and drain the diluent in the reaction cup 20 through the drain device 70, and then inject the blood sample to be tested. In this example, the refractive voltage of the diluent is used to characterize the impurity level of the diluent in the cuvette.
Step S103, obtaining a reference voltage.
In this embodiment, the initial value of the reference voltage may be the initial refractive voltage of the diluent in the cuvette 20 when the blood cell analyzer is started.
Step S104, when detecting that the difference between the refraction voltage of the diluent and the reference voltage exceeds the set threshold, sending a reagent cup cleaning trigger instruction to the cleaning device 30 to clean the reagent cup after the analysis of the tested blood sample is finished, and updating the reference voltage to be the refraction voltage of the diluent in the reagent cup 20 when the reagent cup cleaning is finished. In this embodiment, the cuvette 20 is not cleaned every time the specific protein analysis is completed under the set threshold value.
When detecting that the difference between the refractive voltage of the diluent and the reference voltage exceeds the set threshold, the control device 10 sends a cuvette washing trigger instruction to the washing device, and simultaneously controls the liquid draining device 70 to drain the reaction liquid (including the tested blood sample, the analysis reagent and the like) in the cuvette, and after the reaction liquid is completely drained, the washing device 30 washes the cuvette in response to the cuvette washing trigger instruction. When the difference between the refractive voltage of the diluent and the reference voltage does not exceed the set threshold, the reaction cup is not required to be cleaned at this time, and the liquid discharge device 70 is only controlled to discharge the reaction liquid (including the tested blood sample, the analysis reagent and the like) in the reaction cup, and after the reaction liquid is completely discharged, the diluent injection device 40 is controlled to inject the diluent into the reaction cup 20 and wait for the next specific protein analysis instruction. In this embodiment, the set threshold may be 30mv.
In one embodiment, detecting the refractive voltage of the diluent in the cuvette 20 includes:
the refraction voltage of the diluent in the reaction cup 20 is detected, and the detected refraction voltage of the diluent is put in a preset list.
In one embodiment, referring to fig. 3, the method further includes:
step S105, after the cuvette 20 is cleaned, the preset list is emptied. Thus, after the reaction cup 20 is cleaned, only one refraction voltage in the preset list is the reference voltage; if the cuvette 20 is not cleaned, at least two refractive voltages are included in the preset list.
In one embodiment, the step S103 of obtaining the reference voltage includes:
the number of refraction voltages in the preset list is detected.
If only one refraction voltage is included in the preset list, the refraction voltage is used as a reference voltage;
and if the preset list comprises at least two refraction voltages, taking the refraction voltage of the first preset list as a reference voltage or taking the minimum refraction voltage in the preset list as the reference voltage. Typically, the minimum refractive voltage in the preset list is the refractive voltage that is first placed in the preset list after cleaning.
In one embodiment, the blood cell analyzer is maintained before shutdown, i.e., the reaction cup is cleaned before shutdown, so that when the blood cell analyzer is started, the reaction cup 20 is cleaned, and at this time, the preset list PreVolsList is initialized, i.e., the preset list PreVolsList is emptied, and the sample statistics count=0 is initialized.
When the received specific protein analysis instruction is the first specific protein analysis instruction input by the user after the start-up, the refraction voltage of the diluent in the reaction cup 20 at the moment is obtained, the refraction voltage is put into the first position in the preset list prevolsList and is marked as prevolsList [1], and count+1, meanwhile, the tested blood sample is injected into the reaction cup 20 for specific protein analysis, after the analysis is completed, the reaction liquid is discharged from the reaction cup, at the moment, a reaction cup cleaning trigger instruction is not sent, and the diluent is directly injected into the reaction cup 20 for waiting for the second specific protein analysis instruction.
When the received specific protein analysis instruction is not the first specific protein analysis instruction input by the user after the start-up, the refraction voltage Mean (F (t)) of the diluent in the reaction cup is obtained, and the difference value between Mean (F (t)) and PreVolsList [1] is compared with a set threshold value, wherein the PreVolsList [1] is the reference voltage.
If the difference value does not exceed the set threshold value, a reaction cup cleaning trigger instruction is not sent, after the analysis of specific proteins in the reaction cup 20 is completed and the reaction liquid is discharged from the reaction cup 20, diluent is injected into the reaction cup 20, mean (F (t)) is put into the tail part of a preset list, and count continues to be added with 1; if the difference exceeds the set threshold, a reaction cup cleaning trigger instruction is sent, after the analysis of specific proteins in the reaction cup 20 is completed and the reaction liquid is discharged from the reaction cup, the reaction cup 20 is cleaned, a preset list is emptied, mean (F (t)) is put into the first position in the emptied preset list to be used as a new PreVolsList [1], and Count is set to 0. And so on, after each cleaning, the preset list is emptied, and the refractive voltage of the diluent in the reaction cup 20 acquired next time is put into the first position of the preset list after being emptied, and is used as the reference voltage.
In another embodiment, when the received specific protein analysis command is not the first specific protein analysis command input by the user after the start-up, if the difference between Mean (F (t)) and prevollist [1] does not exceed the set threshold, but the count value obtained after count continues to be added with 1 exceeds the number set threshold, that is, when the number of refraction voltages in the preset list exceeds the number set threshold, a cuvette cleaning trigger command is further sent to clean the cuvette 20, and the preset list is cleared, where count is set to 0.
In another embodiment, when the received specific protein analysis command is the first specific protein analysis command input by the user after the start-up, the refraction voltage of the diluent in the reaction cup 20 is obtained, the refraction voltage is placed at the tail position in the preset list prevolsList, the minimum refraction voltage in the preset list is marked as the preset list [1], namely, the reference voltage is the minimum refraction voltage in the preset list, and count+1, meanwhile, the tested blood sample is injected into the reaction cup 20 for specific protein analysis, after the analysis is completed, the reaction liquid is discharged from the reaction cup 20, at the moment, the reaction cup cleaning trigger command is not sent, and the diluent is directly injected into the reaction cup for waiting for the second specific protein analysis command.
When the received specific protein analysis instruction is not the first specific protein analysis instruction input by the user after the power-on, if the difference between Mean (F (t)) and PreVolsList [1] does not exceed the set threshold, putting Mean (F (t)) into the tail of the preset list, and continuously adding 1 to count. If the difference exceeds the set threshold, a reaction cup cleaning trigger instruction is sent, after the analysis of specific proteins in the reaction cup 20 is completed and the reaction liquid is discharged from the reaction cup 20, the reaction cup 20 is cleaned, a preset list is emptied, mean (F (t)) is put into the tail part of the emptied preset list, the minimum refractive voltage in the preset list is used as a new PreVolsList [1], and Count is set to 0. And so on, after each cleaning, the preset list is emptied, and the refractive voltage of the diluent in the reaction cup 20 acquired next time is put into the first position of the preset list after being emptied, and is used as the reference voltage.
In one embodiment, placing the detected refraction voltage of the diluent in a preset list includes:
upon receiving a specific protein analysis command input by a user, a refractive voltage curve of the diluent in the cuvette is detected until the diluent in the cuvette 20 is emptied, so that a blood sample to be tested is injected into the cuvette 20.
The average value of the refraction voltage curve of the diluent in the reaction cup 20 is calculated, and the average value of the refraction voltage is put in a preset list.
Since the control device 10 needs a time period when receiving a specific protein analysis instruction to empty the diluent in the cuvette 20, the refractive voltage points of the diluent in the cuvette 20 acquired during the time period are fitted into a curve, and the refractive voltage average value of the refractive voltage curve is calculated, and the average value is used as the refractive voltage of the diluent in the acquired cuvette and put into a preset list.
Referring to fig. 4, fig. 4 is a specific protein analysis control apparatus based on a blood cell analyzer according to an embodiment, the control apparatus 10 includes: a receiving instruction unit 101, a specific protein analysis unit 102, an acquisition reference voltage unit 103, and a purge trigger unit 104.
The receiving instruction unit 101 is configured to receive a specific protein analysis instruction input by a user. When a specific protein analysis is required for a new blood sample to be tested, the inspector performs a related operation on the blood cell analyzer such that the control device 10 receives a specific protein analysis instruction for input.
The specific protein analysis unit 102 is configured to detect a refractive voltage of the diluent in the cuvette 20 according to a specific protein analysis instruction inputted by a user, and inject a blood sample to be detected into the cuvette 20 for at least one specific protein analysis. After receiving the specific protein analysis instruction, the control device 10 controls the blood sample to be tested to be injected into the reaction cup 20 through the sample injection device 50, and before the blood sample to be tested is injected into the reaction cup 20, the control device 10 also needs to collect the refraction voltage of the diluent in the reaction cup at the same time, and drain the diluent in the reaction cup 20 through the drain device 70, and then inject the blood sample to be tested.
The acquisition reference voltage unit 103 is used for acquiring a reference voltage. In this embodiment, the initial value of the reference voltage may be the initial refractive voltage of the diluent in the reaction cup when the blood cell analyzer is started.
The cleaning triggering unit 104 is configured to send a cuvette cleaning triggering instruction to the cleaning device when detecting that the difference between the refractive voltage of the diluent and the reference voltage exceeds a set threshold, so as to clean the cuvette 20 after the analysis of the blood sample to be tested is completed, and update the reference voltage to the refractive voltage of the diluent in the cuvette 20 when the cuvette 20 is cleaned.
When detecting that the difference between the refractive voltage of the diluent and the reference voltage exceeds the set threshold, the control device 10 sends a cuvette washing trigger instruction to the washing device, and simultaneously controls the liquid draining device 70 to drain the reaction liquid (including the tested blood sample, the analysis reagent, and the like) in the cuvette 20, and after the reaction liquid is completely drained, the washing device 30 washes the cuvette 20 in response to the cuvette washing trigger instruction. When the difference between the refractive voltage of the diluent and the reference voltage does not exceed the set threshold, the reaction cup 20 is not required to be cleaned at this time, and the liquid draining device 70 is only controlled to drain the reaction liquid (including the tested blood sample, the analysis reagent and the like) in the reaction cup 20, and after the reaction liquid is completely drained, the diluent injecting device 40 is controlled to inject the diluent into the reaction cup 20 and wait for the next specific protein analysis instruction.
In one embodiment, detecting the refractive voltage of the diluent in the cuvette 20 includes:
the refraction voltage of the diluent in the reaction cup 20 is detected, and the detected refraction voltage of the diluent is put in a preset list.
In an embodiment, referring to fig. 5, the control device further includes:
the empty list unit 105 empties the preset list after the cuvette 20 is cleaned.
In one embodiment, obtaining the reference voltage includes:
the number of refraction voltages in the preset list is detected.
If only one refraction voltage is included in the preset list, the refraction voltage is used as a reference voltage;
and if the preset list comprises at least two refraction voltages, taking the refraction voltage of the first preset list as a reference voltage or taking the minimum refraction voltage in the preset list as the reference voltage.
In one embodiment, placing the detected refraction voltage of the diluent in a preset list includes:
upon receiving a specific protein analysis command input by a user, a refractive voltage curve of the diluent in the cuvette is detected until the diluent in the cuvette 20 is emptied, so that a blood sample to be tested is injected into the cuvette 20.
And calculating the average value of the refraction voltage curve of the diluent in the obtained reaction cup, and putting the average value of the refraction voltage into the preset list.
Since the control device 10 needs a time period when receiving a specific protein analysis instruction to empty the diluent in the cuvette, the refractive voltage points of the diluent in the cuvette 20 detected in the time period are fitted into a curve, and the refractive voltage average value of the refractive voltage curve is calculated, and the average value is used as the refractive voltage of the diluent in the cuvette to be put in a preset list.
The foregoing description of the invention has been presented for purposes of illustration and description, and is not intended to be limiting. Several simple deductions, modifications or substitutions may also be made by a person skilled in the art to which the invention pertains, based on the idea of the invention.
Claims (10)
1. A method for analyzing a specific protein based on a blood cell analyzer, the blood cell analyzer comprising a cuvette for analyzing a specific protein of a blood sample to be tested, and a washing device for washing the cuvette, the method comprising:
receiving a specific protein analysis instruction input by a user;
according to the specific protein analysis instruction input by the user, detecting the refraction voltage of the diluent in the reaction cup, and injecting the detected blood sample into the reaction cup for at least one specific protein analysis, wherein the refraction voltage corresponds to the refraction index and is used for representing the impurity degree of the diluent in the reaction cup;
acquiring a reference voltage, wherein the initial value of the reference voltage is the initial refraction voltage of the diluent in the reaction cup;
when detecting that the difference value between the refraction voltage of the diluent and the reference voltage exceeds a set threshold value, sending a reaction cup cleaning trigger instruction to the cleaning device so as to clean the reaction cup after the analysis of the blood sample to be tested is finished, and updating the reference voltage to be the refraction voltage of the diluent in the reaction cup when the reaction cup is finished after the cleaning of the reaction cup.
2. The method as recited in claim 1, further comprising:
and detecting the refraction voltage of the diluent in the reaction cup, and putting the detected refraction voltage of the diluent into a preset list.
3. The method of claim 2, wherein the method further comprises:
after the reaction cup is cleaned, the preset list is emptied.
4. The method of claim 3, wherein the obtaining the reference voltage comprises:
detecting the quantity of refraction voltages in the preset list;
if the preset list only comprises one refraction voltage, taking the refraction voltage as a reference voltage;
and if the preset list comprises at least two refraction voltages, taking the refraction voltage of the first preset list as a reference voltage or taking the minimum refraction voltage in the preset list as the reference voltage.
5. The method of claim 2, wherein said placing the detected refraction voltage of the diluent in a preset list comprises:
detecting a refraction voltage curve of the diluent in the reaction cup when a specific protein analysis instruction input by a user is received until the diluent in the reaction cup is emptied, so that the tested blood sample is injected into the reaction cup;
and calculating the average value of the refraction voltage curve of the diluent in the obtained reaction cup, and putting the average value of the refraction voltage into the preset list.
6. A specific protein analysis control apparatus based on a blood cell analyzer, the blood cell analyzer comprising a cuvette for performing a specific protein analysis on a blood sample to be measured, and a washing apparatus for washing the cuvette, the control apparatus comprising:
the receiving instruction unit is used for receiving a specific protein analysis instruction input by a user;
the specific protein analysis unit is used for detecting the refraction voltage of the diluent in the reaction cup according to the specific protein analysis instruction input by the user, and injecting the tested blood sample into the reaction cup for at least one specific protein analysis, wherein the refraction voltage corresponds to the refraction index and is used for representing the impurity degree of the diluent in the reaction cup;
the reference voltage acquisition unit is used for acquiring reference voltage, and the initial value of the reference voltage is the initial refraction voltage of the diluent in the reaction cup;
and the cleaning triggering unit is used for sending a reaction cup cleaning triggering instruction to the cleaning device when detecting that the difference value between the refraction voltage of the diluent and the reference voltage exceeds a set threshold value so as to clean the reaction cup after the analysis of the blood sample to be tested is finished, and updating the reference voltage to the refraction voltage of the diluent in the reaction cup when the reaction cup is finished after the cleaning of the reaction cup is finished.
7. The control device of claim 6, wherein said obtaining the refractive voltage of the diluent in the cuvette comprises:
and detecting the refraction voltage of the diluent in the reaction cup, and putting the detected refraction voltage of the diluent into a preset list.
8. The control device according to claim 7, characterized in that the control device further comprises:
and the emptying list unit is used for emptying the preset list after the reaction cup is cleaned.
9. The control apparatus of claim 7, wherein the obtaining the reference voltage comprises:
detecting the quantity of refraction voltages in the preset list;
if the preset list only comprises one refraction voltage, taking the refraction voltage as a reference voltage;
and if the preset list comprises at least two refraction voltages, taking the refraction voltage of the first preset list as a reference voltage or taking the minimum refraction voltage in the preset list as the reference voltage.
10. The control device of claim 7, wherein said placing the detected refraction voltage of the diluent in a preset list comprises:
detecting a refraction voltage curve of the diluent in the reaction cup when a specific protein analysis instruction input by a user is received until the diluent in the reaction cup is emptied, so that the tested blood sample is injected into the reaction cup;
and calculating the average value of the refraction voltage curve of the diluent in the obtained reaction cup, and putting the average value of the refraction voltage into the preset list.
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| CN110596046B (en) * | 2018-06-12 | 2023-06-13 | 深圳市理邦精密仪器股份有限公司 | Reaction cup detection method and device based on laser scattering component and storage medium |
| CN109738659B (en) * | 2018-12-25 | 2023-01-13 | 深圳市理邦精密仪器股份有限公司 | Reaction cup processing method and device based on dirty cup detection and terminal equipment |
| CN110456088B (en) * | 2019-08-27 | 2023-05-09 | 北京世纪沃德生物科技有限公司 | Specific protein analyzer |
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