KR101762877B1 - Mixing apparatus of blood and reagent - Google Patents

Mixing apparatus of blood and reagent Download PDF

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Publication number
KR101762877B1
KR101762877B1 KR1020160012749A KR20160012749A KR101762877B1 KR 101762877 B1 KR101762877 B1 KR 101762877B1 KR 1020160012749 A KR1020160012749 A KR 1020160012749A KR 20160012749 A KR20160012749 A KR 20160012749A KR 101762877 B1 KR101762877 B1 KR 101762877B1
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KR
South Korea
Prior art keywords
blood
reagent
mixing
metering valve
valve unit
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KR1020160012749A
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Korean (ko)
Inventor
전태호
이규만
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(주)뉴옵틱스
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/102—Preventing or detecting loss of fluid by dripping
    • G01N2035/1023—Preventing or detecting loss of fluid by dripping using a valve in the tip or nozzle

Abstract

The present invention relates to a device for mixing a blood and a reagent used in a hematology analyzer by withdrawing and mixing blood and reagents from a blood storage container for storing blood and a reagent storage container for storing reagents for blood inspection, A plurality of reagent storage containers each storing a plurality of reagents for blood testing, a mixing module for mixing the blood and the reagents, a plurality of sample storage containers for storing the test samples mixed in the mixing module, And a control module for controlling the mixing module to control the amount of the reagent supplied to the plurality of sample storage containers in the plurality of reagent storage containers according to the input amount of the reagent or the reagent. The supply of blood and reagents for the blood sample can be performed automatically.

Description

[0002] Mixing apparatus of blood and reagent [

The present invention relates to a blood and reagent mixing apparatus. More particularly, the present invention relates to a blood and reagent mixing apparatus for extracting blood and reagents from a blood storage container for storing blood and a reagent storage container for storing reagents for blood testing, Reagent mixing apparatus.

In general, the concentration of electrolytes, gaseous species and metabolites in the blood, or the hematocrit ratio maintains the homeostasis in the human body, and when concentration imbalance occurs, it causes various diseases with excessive or deficiency of the concentration. Thus, rapid measurement of blood electrolytes, gaseous species and metabolites, or hematocrit, helps clinicians to quickly predict the dysfunction and disease progression of the body from bioequivalence.

One of the methods for examining such blood is the Complete Blood Cell Count (CBC) test widely used. These CBC tests are one of the most basic blood tests with various clinical indications ranging from diagnosis, treatment and follow-up of the disease. Through this test, information on three types of cells (blood cells) present in the blood, that is, red blood cells, white blood cells and platelets, can be obtained by using various parameters.

Analysis of blood samples is generally based on the total number of leukocytes, specifically leukocytes by sub-population (basophils, eosinophils, neutrophils, monocytes, and lymphocytes) The number of red blood cells and platelets, and the level of hemoglobin.

For example, an assay for hemoglobin is performed after dissolution of red blood cells, that is, after membrane breakage of red blood cells, and by spectrophotometric determination of hemoglobin separated from the medium, and also by measuring the absorption ability of a single compound at an appropriate wavelength Stabilization of the complex form of hemoglobin (oxyhemoglobin or cyanomethemoglobin) is required for measurement. The total leukocyte count for the blood sample is made by resistivity, which combines the specific dissolution of red blood cells and the protection of leukocytes.

In order to obtain numerical information of blood cells, an automatic hematology analyzer which automatically measures the number of blood cells in a certain volume after appropriately diluting blood is widely used. Numerical data of hemocyte can be obtained by the technique of measuring the number of cells through a microscope using a hemocytometer, but an automated hematology analyzer is more widely used because it can measure various indices other than numerical information .

Examples of such techniques are described in documents 1 and 2 below.

For example, as shown in Fig. 1, the following patent document 1 discloses a single dilution and analytical tank (1) in which a blood sample (2), a reagent (4) and a dilution liquid (4) (5) for measuring the hemoglobin level in the analysis solution by photometry, and means (5) for measuring the total number of white blood cells. Means 6 are provided and means are provided for taking a portion of the analysis solution from the analysis tank 1 and injecting it into the optical tank 7 provided with the optical measurement means 8 for leukocyte analysis, And a dilution tank (9) provided with means (10) for taking a part of the pre-solution consisting of a diluent and measuring the resistance of a part of the pre-solution for counting red blood cells and platelets Sudan too And an automatic blood sample analyzer provided therein.

Patent Document 2 discloses a strap in which a plurality of receiving holes are formed to receive a blood sample of a patient, a diluting liquid dispensing period in which a diluting liquid is injected into a receiving hole of the strap, and a diluting liquid dispensing period in which the strap is seated, A nozzle for sucking diluted blood located in each of the receiving holes, a suction unit for sucking blood through the nozzle, and a sucking unit for sucking the blood sucked through the nozzle, And a water introducing portion for adding water to the blood sucked through the suction portion. The washer is installed at a lower portion of the washer and is disposed at one end of the shaker, A lifting portion for lifting the strap downward, a lower portion of the strap lowered by the lifting portion, And an enzyme-based reagent solution dispenser for dispensing the enzyme reagent solution into the receiving hole.

Korean Patent Publication No. 2007-0116680 (published Dec. 10, 2007) Korean Registered Patent No. 10-1524672 (Registered May 5, 2015)

However, in the hemophilia testing apparatus of the prior art as described above, since the reagent for blood cell examination is only automated as a preset condition, the inefficiency of performing the setting of the apparatus itself due to the change of the reagent amount or the change of the reagent type, And inconvenience that waste of time is caused.

In addition, since the number of specimens to be processed per equipment is relatively small in the conventional technology as described above, there is a problem that more than five testing devices must be used for a complex blood test.

SUMMARY OF THE INVENTION An object of the present invention is to provide a mixing apparatus for a blood and a reagent capable of automatically supplying a reagent in response to a reagent amount change or a reagent kind change.

Another object of the present invention is to provide a device for mixing blood and a reagent for cleaning a reagent supply path when changing reagent types.

In order to achieve the above object, the apparatus for mixing blood and reagent according to the present invention comprises a blood storage container for storing blood, a plurality of reagent storage containers for storing a plurality of reagents for blood testing, Module, a plurality of sample storage containers for storing the test sample mixed in the mixing module, a reagent reservoir for regulating the amount of the reagent supplied to the plurality of sample storage containers according to the type of the reagent or the amount of the reagent And a control module for controlling the mixing module.

In the apparatus for mixing blood and reagent according to the present invention, the mixing module may include a first quantitative valve unit for regulating the supply amount of the blood and a second quantitative valve unit for regulating a supply amount of the reagent.

In addition, in the apparatus for mixing blood and reagent according to the present invention, the control module may include a storage unit for storing information on the amounts of blood and reagents for blood testing, Or a second control valve for controlling the second metering valve unit.

In the apparatus for mixing blood and reagent according to the present invention, the control unit controls the second metering valve unit to operate after operating the first metering valve unit.

In the apparatus for mixing blood and reagent according to the present invention, the first metering valve unit or the second metering valve unit is operated by a hydraulic cylinder or a pneumatic cylinder, respectively.

In the apparatus for mixing blood and reagent according to the present invention, the first metering valve unit or the second metering valve unit is provided with a hydraulic circuit and a solenoid valve which are operated by electrical signals from the control unit, respectively .

In addition, in the mixing device for blood and reagent according to the present invention, the mixing module may further comprise a mixing pipe for mixing the reagent and the blood discharged through the first and second metering valve portions, A reagent supply path for supplying a reagent is provided in the second metering valve portion, and the mixing device further comprises a cleaning module for cleaning the reagent supply path .

In the apparatus for mixing blood and reagent according to the present invention, a mixing channel is provided in the mixing channel, one end of the mixing channel is connected to the blood supply channel, and the other end of the mixing channel is connected to the reagent supply channel And the blood supplied from the blood storage container is supplied to the needles through an L-shaped channel, and the reagent supplied from the reagent storage container is supplied to the needle Is supplied.

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As described above, according to the apparatus for mixing blood and reagent according to the present invention, it is possible to provide a mixing module for mixing blood and reagent, and to provide a mixing module for mixing the reagent with the reagent, The supply of the blood and the reagent for the diagnosis of a plurality of kinds of blood can be automatically performed.

Further, according to the apparatus for mixing blood and reagent according to the present invention, by providing a cleaning means for cleaning the reagent supply path, it is also possible to automatically clean the mixing module when changing the diagnostic reagent.

1 is a block diagram of a conventional blood sample automatic analyzing apparatus,
FIG. 2 is a view for explaining the constitution of a mixing device of blood and reagent according to the present invention,
FIG. 3 is a block diagram of an apparatus for mixing blood and reagents according to the present invention;
FIG. 4 is a block diagram for explaining the configuration of the control module shown in FIG. 3;
5 is a flow chart for explaining a method of mixing blood and a reagent according to the present invention.

These and other objects and novel features of the present invention will become more apparent from the description of the present specification and the accompanying drawings.

The term 'module' as applied to the present invention means that the device, component or apparatus is set to be part of a larger apparatus or apparatus with one or more parts or independent apparatuses. This module works with other modules to perform one or more tasks such as independent or diagnostic analysis.

&Quot; Reagent " as applied to the present invention refers to the entirety of the original sample or any portion thereof, unless the context clearly indicates otherwise, and the reagent compound is selected in an amount suitable for the target analysis so as to be chemically mutually friendly. This compound can be selected from the compounds conventionally used in the prior art. For example, a commercially available preparation containing a commercially available preparation, a compound for dissolving red blood cells and a leukocyte protective compound conventionally used for performing leukocyte differentiation is used, and a third reagent compound for stabilizing hemoglobin in the form of a colored complex May be added.

The 'sample' applied to the present invention means that a predetermined amount of blood and a predetermined amount of reagent are mixed for blood test.

Hereinafter, the configuration of the present invention will be described with reference to the drawings.

3 is a block diagram of an apparatus for mixing blood and a reagent according to the present invention, and FIG. 4 is a block diagram of a control apparatus for mixing a blood and a reagent according to the present invention, Fig. 7 is a block diagram for explaining a configuration of the first embodiment.

2 and 3, the apparatus for mixing blood and reagent according to the present invention comprises a blood storage container 100 for storing blood for diagnosis, a plurality of reagents for storing a plurality of reagents for blood testing, A mixing chamber 300 for mixing the blood and the reagent, a plurality of sample storage vessels 400 for storing the samples for inspection mixed in the mixing module, And a control module 500 for controlling the mixing module 300 to control the amount of reagent supplied from the plurality of reagent storage containers 200 to the plurality of sample storage containers 400.

The blood storage container 100 is a test tube for collecting and storing the blood of an examinee for normal blood diagnosis, and is kept sealed by the cap. 2, the barcode 110 for blood is attached to the blood storage container 100, and the information on the inspector for blood testing and the name of the diagnosis for diagnosis are stored in the barcode 110 for blood , And read by a bar code reader provided in the diagnostic apparatus during the transfer process for inspection.

The reagent storage container 200 is a container for storing a reagent that reacts with blood stored in the blood storage container 100, and is not limited to a specific shape. Such a reagent storage container includes a plurality of reagent types, for example, a reagent for diagnosing leukocytes, a reagent for diagnosing red blood cells, a reagent for diagnosing hemoglobin, and the like. As shown in FIG. 2, a reagent barcode 210 is attached to each of the reagent storage containers 200, and the reagent barcode 210 is provided with information on reagents, for example, Information on the amount of reagent to be injected, and the like. The reagent bar code 210 is read by a bar code reader provided in the diagnostic apparatus, and the read information is transmitted to the control module 500.

The blood stored in the blood storage container 100 and the reagents stored in the respective reagent storage containers 200 are taken out by a conventional extraction mechanism (not shown) and supplied to the mixing module 300. Therefore, the drawing mechanism can be integrally coupled to the mixing module.

As shown in FIG. 2, the mixing module 300 includes a first metering valve unit 310 for controlling the supply amount of blood supplied from the drawing mechanism to the sample storage container 400, A second metering valve unit 320 for controlling the supply amount of the reagent supplied to the sample storage container 400, and a mixing pipe 330. As shown in FIG. 2, the first metering valve unit 310 is provided with a blood injection port 311 through which blood drawn out from the blood storage container 100 is injected. In the second metering valve unit 320, A reagent injection port 321 through which the reagent withdrawn from the container 200 is injected is provided.

The first metering valve unit 310 is provided with a blood supply path 312 for supplying blood and the second metering valve unit 320 is provided with a reagent supply path 322 for supplying a reagent, An orifice plate is provided at an outlet portion of the valve portion 310 and the second metering valve portion 320 toward the mixing pipe 330. Therefore, the blood injected into the blood supply path 312 by the orifice plate and the reagent injected into the reagent supply path 322 are temporarily held on the supply path, and the first metering valve part 310 or the second metering valve And is discharged to the mixing pipe 330 by the operation of the part 320.

One end of the mixing channel is connected to the blood supply channel 312 and the other end of the mixing channel is connected to the reagent supply channel 322.

The discharging needle 331 for discharging the mixed sample to the sample storage container 400 for storing the mixed sample in the mixing channel of the mixing tube 330 is attached to the lower part of the other channel of the mixing channel, As shown in Fig. Therefore, the blood supplied from the blood storage container 100 is supplied to the needle 331 through a substantially L-shaped channel as shown in FIG. 2, and the reagent supplied from the reagent storage container 200 is supplied to the needle 331 in a substantially linear To the needle 331.

The first metering valve unit 310 or the second metering valve unit 320 includes a hydraulic circuit and a solenoid valve, a hydraulic cylinder, or a pneumatic cylinder, each of which operates by an electric signal from the control module 500 . The operation of the first metering valve unit 310 or the second metering valve unit 320 is the same as that of a normal metering valve, and is operated by a hydraulic cylinder or a pneumatic cylinder, so a detailed description thereof will be omitted.

Meanwhile, in the apparatus for mixing blood and reagent according to the present invention, a cleaning module 600 is provided for cleaning the reagent supply path 321 when the reagent is changed and injected.

When the reagent is changed, the reagent supply path 322 by the cleaning module 600 is changed to the reagent supply path 322 because the blood is supplied through the L-shaped channel for supplying the sample to the sample storage container 400, ) Can be performed, so that the cleaning operation can be easily performed. That is, when the blood and the reagent are supplied to the mixing module 300, the blood is supplied to the blood supply path 312 after the reagent is supplied through the reagent supply path 322, so that the reagent supply by the cleaning module 600 The cleaning of the furnace 322 can be easily performed by cleaning only the straight portion,

Such a cleaning module 600 can be easily realized by a cleaning device of an ordinary diagnostic device.

2, the inner diameter of the blood supply path 312 and the inner diameter of the reagent supply path 322 are substantially the same. However, the present invention is not limited to this, and the first metering valve portion 310 or the second metering valve portion 320, The length of the blood supply path 312 is longer than the length of the reagent supply path 322 so that the inner diameter of the blood supply path 312 is longer than the inner diameter of the reagent supply path 322 It may be formed narrowly.

The sample storage container 400 is provided with a plurality of sample storage containers 400 corresponding to the kind of the reagent or the kind of the reagent according to the diagnosis type of the examinee and collects blood of the examinee for normal blood diagnosis It is preferable to maintain the sealed state by the cap. Also, as shown in FIG. 2, the sample storage container 400 is also equipped with a bar code, so that the examination object of the sample can be discriminated and confirmed.

As shown in FIG. 4, the control module 500 includes a storage unit 510 for storing information on the amount of blood and a reagent for blood testing, 1 control valve unit 310 or a control unit 520 for controlling the second metering valve unit 320.

The storage unit 510 is constituted by a conventional memory device and stores information on the type of the reagent, information on the blood diagnosis, degree of the amount of the reagent to be injected according to the blood diagnosis, and the like. The control unit 520 is configured by a microprocessor and controls the hydraulic circuit provided in the first metering valve unit 310 and the second metering valve unit 320 in response to information stored in the storage unit 510, To control the solenoid valve. When the control unit 520 receives an instruction to change the reagent, the control unit 520 controls the cleaning module 600 by referring to the information stored in the memory 510 to facilitate the cleaning of the reagent supply path 322 .

The control unit 520 controls the second metering valve unit 320 to control the amount of reagent discharged according to the information of the reagent barcode 210 defining each reagent in the plurality of reagent storage containers 200 It is possible.

Next, a method of mixing blood and a reagent according to the present invention will be described with reference to FIG.

5 is a flowchart illustrating a method of mixing blood and reagent according to the present invention.

The method for mixing blood and a reagent according to the present invention is a method for withdrawing and mixing blood and a reagent in a blood storage container for storing blood and a plurality of reagent storage containers for storing a plurality of reagents for blood testing, A predetermined amount of blood for the blood test is taken out from the container 100 (S100).

On the other hand, the control unit 520 determines the blood supply amount in accordance with the command inputted to perform the blood diagnosis (S110), and controls the first metering valve unit 310. That is, the amount of supply (discharge) of blood drawn out of the blood storage container 100 and held in the blood supply path 312 through the blood injection port 311 is determined, and accordingly, the first metering valve unit 310 is controlled do.

In addition, a predetermined amount of reagent for blood test is drawn out from the plurality of reagent storage containers 200 (S200). The control unit 520 determines a reagent supply amount in accordance with the inputted command to perform blood diagnosis (S210), and controls the second metering valve unit 320. [ That is, the amount of supply (discharge) of the reagent drawn out from the blood storage container 100 and held in the reagent supply path 322 through the reagent injection port 321 is determined, and accordingly, the second metered dose valve unit 320 is controlled do.

The determination of the supply (discharge) amount of the reagent in the control unit 520 may be performed by a user instruction of the diagnostic apparatus to which the present invention is applied, memory information stored in the storage unit 510, It is also possible to control the amount of the reagent to be discharged by controlling the second metering valve unit 320 according to the information of the reagent bar code 210 defining each reagent.

The blood and the reagent are discharged under the control of the first and second metering valve units 310 and 320 to mix the blood and the reagent at the other end of the mixing tube 330 at step S300, Is stored in the sample storage container 400 via the needle 331 provided in the sample container 330 (S310).

The control of the first metering valve unit 310 by the control unit 520 and the control of the second metering valve unit 320 by the control unit 520 in step S220 may be performed simultaneously in step S120. However, the present invention is not limited to this, and the controller 520 may control the first metering valve unit 310 and then the control unit 520 sequentially control the second metering valve unit 320.

In addition, in step S220, the control unit 520 variably controls the control of the second metering valve unit 320 such that the amount of the reagent drawn out in the plurality of reagent storage vessels differs depending on the type of the reagent.

Next, if the kind of the reagent is changed in the plurality of reagent storage containers 200 with respect to the same blood after the step S310 (S320), the reagent supply path 321 is cleaned in the mixing module 300 S340). Then, the process proceeds to step S210 and the above-described process is repeated.

In the above description, the configuration for changing the amount of reagent and the type of reagent for the same blood has been described. However, the present invention is not limited to this, and the same reagent may be applied to other blood. That is, in the above description, the amount of blood supplied through the first metering valve unit 310 is controlled and the supply amount of the reagent is controlled through the second metering valve unit 320. However, in the first metering valve unit 310, The amount of blood supplied through the second metering valve unit 320 may be controlled.

If the cleaning is not performed in step S320, the process is terminated (S330). However, it is preferable to clean the entire mixing module 300 not for the simple termination but for mixing the reagent with another blood.

Although the present invention has been described in detail with reference to the above embodiments, it is needless to say that the present invention is not limited to the above-described embodiments, and various modifications may be made without departing from the spirit of the present invention.

By using the apparatus for mixing blood and reagent according to the present invention, it is possible to automatically supply blood and reagent for diagnosis of a plurality of kinds of blood.

100: Blood storage container
200: a plurality of reagent storage containers
300: Mixed module
400: a plurality of sample storage containers
500: control module
600: Cleaning module

Claims (13)

Blood storage containers for storing blood,
A plurality of reagent storage vessels, each storing a plurality of reagents for blood testing,
A mixing module for mixing the blood and the reagent,
A plurality of sample storage containers for storing the mixed test samples in the mixing module,
And a control module for controlling the mixing module to control the amount of the reagent supplied to the plurality of sample storage containers in the plurality of reagent storage containers according to the kind of the reagent or the input amount of the reagent,
Wherein the mixing module includes a first metering valve unit for adjusting a supply amount of the blood,
A second metering valve unit for regulating the supply amount of the reagent,
And a mixing tube for mixing the reagent and the blood discharged through the first and second metering valve portions,
Wherein the first metering valve unit is provided with a blood supply path for supplying blood and the second metering valve unit is provided with a reagent supply path for supplying reagents,
The reagent supply path is cleaned by a cleaning module,
Wherein the mixing channel is provided with a mixing channel, one end of the mixing channel is connected to the blood supply channel, the other end of the mixing channel is connected to the reagent supply channel, and a needle And,
Wherein the blood supplied from the blood storage container is supplied to the needle through an L-shaped channel, and the reagent supplied from the reagent storage container is supplied linearly to the needle. delete The method of claim 1,
The control module may include a storage unit for storing information on the amount of blood and a reagent for blood test, and a control unit for controlling the first metering valve unit or the second metering valve unit according to the information stored in the storage unit Characterized in that the blood and reagent mixing device. 4. The method of claim 3,
Wherein the controller controls the second metering valve unit to operate after operating the first metering valve unit. 4. The method of claim 3,
Wherein the first metering valve unit or the second metering valve unit is operated by a hydraulic cylinder or a pneumatic cylinder, respectively. 4. The method of claim 3,
Wherein the first metering valve unit or the second metering valve unit comprises a hydraulic circuit and a solenoid valve which are operated by electrical signals from the control unit, respectively. delete delete delete delete delete delete delete
KR1020160012749A 2016-02-02 2016-02-02 Mixing apparatus of blood and reagent KR101762877B1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113030477A (en) * 2019-12-25 2021-06-25 深圳迈瑞生物医疗电子股份有限公司 Measuring method, measuring device for specific protein and storage medium

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113030477A (en) * 2019-12-25 2021-06-25 深圳迈瑞生物医疗电子股份有限公司 Measuring method, measuring device for specific protein and storage medium
CN113030477B (en) * 2019-12-25 2024-01-26 深圳迈瑞生物医疗电子股份有限公司 Measurement method, measurement device for specific protein and storage medium

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