CN112098649B - 一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 - Google Patents
一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 Download PDFInfo
- Publication number
- CN112098649B CN112098649B CN202010821541.6A CN202010821541A CN112098649B CN 112098649 B CN112098649 B CN 112098649B CN 202010821541 A CN202010821541 A CN 202010821541A CN 112098649 B CN112098649 B CN 112098649B
- Authority
- CN
- China
- Prior art keywords
- nano
- afp
- signal controlled
- antibody
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57476—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncofetal proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010821541.6A CN112098649B (zh) | 2020-08-15 | 2020-08-15 | 一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010821541.6A CN112098649B (zh) | 2020-08-15 | 2020-08-15 | 一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN112098649A CN112098649A (zh) | 2020-12-18 |
CN112098649B true CN112098649B (zh) | 2022-12-02 |
Family
ID=73752884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010821541.6A Active CN112098649B (zh) | 2020-08-15 | 2020-08-15 | 一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN112098649B (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105738457A (zh) * | 2016-03-07 | 2016-07-06 | 济南大学 | 一种基于金属基标记同时检测两种肿瘤标志物的磁性电化学免疫传感器的制备方法及应用 |
CN106248951A (zh) * | 2016-07-11 | 2016-12-21 | 福州市传染病医院 | 一种检测galectin‑4的荧光酶联免疫分析方法 |
WO2019067656A1 (en) * | 2017-09-29 | 2019-04-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | POLYDOPAMIN ENCAPSULATED NANODIAMANTS AND RELATED METHODS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9346913B2 (en) * | 2012-01-05 | 2016-05-24 | Nanyang Technological University | Methods of preparing monodispersed polydopamine nano- or microspheres, and methods of preparing nano- or microstructures based on the polydopamine nano- or microspheres |
-
2020
- 2020-08-15 CN CN202010821541.6A patent/CN112098649B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105738457A (zh) * | 2016-03-07 | 2016-07-06 | 济南大学 | 一种基于金属基标记同时检测两种肿瘤标志物的磁性电化学免疫传感器的制备方法及应用 |
CN106248951A (zh) * | 2016-07-11 | 2016-12-21 | 福州市传染病医院 | 一种检测galectin‑4的荧光酶联免疫分析方法 |
WO2019067656A1 (en) * | 2017-09-29 | 2019-04-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | POLYDOPAMIN ENCAPSULATED NANODIAMANTS AND RELATED METHODS |
Non-Patent Citations (2)
Title |
---|
pH responsive amperometric immunoassay for carcinoma antigen 125 based on hollow polydopamine encapsulating methylene blue;Xiaoyu Liang等;《Sensors & Actuators: B. Chemical》;20190408;第290卷;第625页摘要,第626页左栏2.3部分 * |
聚多巴胺/金纳米空心球的原位制备及其在电化学免疫分析中的应用;王贝贝等;《湖北省第五届大学生化学(化工)学术创新成果报告会论文集》;20170425;第96-99页 * |
Also Published As
Publication number | Publication date |
---|---|
CN112098649A (zh) | 2020-12-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108344783B (zh) | 一种电化学细胞传感器及其制备方法和应用 | |
CN111693571B (zh) | 一种基于光寻址电位传感器检测gpc3的方法 | |
CN111766289B (zh) | 一种基于富氧空位CeO2电致化学发光免疫传感器的制备方法 | |
CN111208178B (zh) | 一种基于钴基金属有机框架物双重放大苝四羧酸信号构建电化学发光传感器的方法 | |
WO2021180132A1 (zh) | 基于Fe2O3材料单层光电化学传感器的癌胚抗原检测方法 | |
CN113155930B (zh) | 一种多重信号放大技术检测白血病干细胞肿瘤标志物cd123的电化学免疫传感方法 | |
CN110133252A (zh) | 用于检测癌胚抗原的试剂盒和检测方法及其应用 | |
CN109613244B (zh) | 一种Ag@Pt-CuS标记的免疫传感器的制备方法及应用 | |
CN109884029A (zh) | 银/石墨烯量子点纳米酶、sers检测试剂盒及应用 | |
Zhong et al. | Dual-wavelength responsive photoelectrochemical aptasensor based on ionic liquid functionalized Zn-MOFs and noble metal nanoparticles for the simultaneous detection of multiple tumor markers | |
Lu et al. | Detection of squamous cell carcinoma antigen in cervical cancer by surface-enhanced Raman scattering-based immunoassay | |
CN112098648B (zh) | 一种检测肝癌患者血清生物标志物的方法 | |
CN114235907B (zh) | 用于非小细胞肺癌cyfra21-1检测的电化学发光免疫传感器及检测方法 | |
CN112098649B (zh) | 一种检测肝癌患者血清生物标志物的信号控释纳米材料及其制备方法 | |
CN112526135A (zh) | 一种检测前列腺特异性抗原的光电化学生物传感器的制备方法及应用 | |
CN109991298B (zh) | 一种Pt@MOF-GO标记的电化学传感器的制备方法及应用 | |
CN111337557A (zh) | 一种基于CeO2@MnO2的免疫传感器的制备方法及应用 | |
CN111766288B (zh) | 一种基于富氧空位NiCo2O4电致化学发光传感器的制备方法 | |
Wang et al. | High-sensitive electrochemiluminescent analysis based on co-reactive high-molecular polymer and dual catalysis to generate oxygen in situ | |
CN113281389A (zh) | 一种基于2,4,6-三氨基嘧啶调控的类石墨相氮化碳的电化学免疫传感器的制备方法 | |
CN114675027B (zh) | 膀胱癌蛋白类标志物活性检测试剂盒及其检测方法 | |
CN113267632B (zh) | 一种基于多功能聚乙烯亚胺介导的检测心肌梗死标志物的无标记电化学发光免疫阵列传感器 | |
CN109884316A (zh) | 一种用于检测肿瘤m2型丙酮酸激酶的试剂盒及制备方法 | |
CN111721825B (zh) | 一种基于镧系金属自发光Au@Gd-MOFs的信号增强型免疫传感器的制备方法 | |
Salimi et al. | Electrochemical immunosensor based on carbon nanofibers and gold nanoparticles for detecting anti-Toxoplasma gondii IgG antibodies |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20230602 Address after: No. 201, 2nd Floor, Comprehensive Building 1, E-commerce Industrial Park, National Xuchang Economic and Technological Development Zone, 100 meters southeast of the intersection of Ruixiang Road and Ziyang Road, Xuchang City, Henan Province, 461000 Patentee after: Xuchang Boao Runkang Medical Laboratory Co.,Ltd. Address before: 230000 floor 1, building 2, phase I, e-commerce Park, Jinggang Road, Shushan Economic Development Zone, Hefei City, Anhui Province Patentee before: Dragon totem Technology (Hefei) Co.,Ltd. Effective date of registration: 20230602 Address after: 230000 floor 1, building 2, phase I, e-commerce Park, Jinggang Road, Shushan Economic Development Zone, Hefei City, Anhui Province Patentee after: Dragon totem Technology (Hefei) Co.,Ltd. Address before: 266000 Songling Road, Laoshan District, Qingdao, Shandong Province, No. 99 Patentee before: QINGDAO University OF SCIENCE AND TECHNOLOGY |