CN112076266A - Ganoderma lucidum spore powder buccal tablet and preparation method thereof - Google Patents
Ganoderma lucidum spore powder buccal tablet and preparation method thereof Download PDFInfo
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- CN112076266A CN112076266A CN202011059977.2A CN202011059977A CN112076266A CN 112076266 A CN112076266 A CN 112076266A CN 202011059977 A CN202011059977 A CN 202011059977A CN 112076266 A CN112076266 A CN 112076266A
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- 240000008397 Ganoderma lucidum Species 0.000 title claims abstract description 84
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- 229940046011 buccal tablet Drugs 0.000 title claims abstract description 58
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- 241000222336 Ganoderma Species 0.000 abstract description 20
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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Abstract
A buccal tablet of ganoderma spore powder and its preparation method relate to the technical field of health products, the buccal tablet of ganoderma spore powder is prepared from ganoderma spore powder as main material, and various Chinese medicinal materials such as ginseng, cordyceps, notoginseng, medlar, etc. can invigorate qi and blood, tranquilize mind and improve human immunity after long-term administration. In addition, the walnut and the hawthorn are added to improve the taste, so that the whole ganoderma lucidum spore powder buccal tablet has better taste while keeping the drug effect, and is more beneficial to the acceptance of people. The preparation method of the ganoderma lucidum spore powder buccal tablet is simple to operate, has low requirements on equipment, and can be used for quickly manufacturing the ganoderma lucidum spore powder buccal tablet on a large scale.
Description
Technical Field
The invention relates to the technical field of health products, and particularly relates to a ganoderma lucidum spore powder buccal tablet and a preparation method thereof.
Background
The Ganoderma spore powder is prepared by collecting spore ejected from the fungus tube after Ganoderma fruiting body is mature. It has the essence of glossy ganoderma and high nutritive value. The Ganoderma spore powder contains various amino acids, inorganic nutrient elements, triterpenes, alkaloids, sterols, nucleosides, high molecular polysaccharides and other physiologically active substances. Modern pharmacology proves that the ganoderma lucidum spore powder has the effects of regulating immunity, activating macrophages, regulating glucocorticoid and the like. Because the ganoderma lucidum spores have double layers of tough chitin and peptidoglycan outer walls, the human body cannot digest the ganoderma lucidum cell walls. Research proves that morphological changes before and after wall breaking of ganoderma lucidum spore powder are obvious; the content of reducing sugar and peptide in the spore powder extract after wall breaking is obviously higher than that before wall breaking. Animal experiments prove that under the same dosage, the effect of the spore powder on the immune function of a mouse after wall breaking is obviously greater than that before wall breaking. The biological efficacy of the ganoderma lucidum spore powder can be fully exerted by adopting an effective method to break the wall. The wall-broken ganoderma lucidum spore powder is prepared from ganoderma lucidum spore powder, is enrichment or concentration of all bioactive components in the ganoderma lucidum spore powder, and removes ganoderma lucidum spore cell walls which can not be digested and decomposed by human bodies, so that bioactive substances in the ganoderma lucidum spores are convenient for the absorption and utilization of the human bodies. In the prior art, the ganoderma lucidum spore powder has fewer related health care products, single taste and eating mode and can not meet the diversified demands of the public.
Disclosure of Invention
The invention aims to provide the ganoderma lucidum spore powder buccal tablet which is scientific and reasonable in formula, and the ganoderma lucidum spore powder is mixed with other medicinal materials and food materials to prepare the buccal tablet, so that the buccal tablet not only has better nutritional value, but also has better taste, and is popular with the public.
The invention also aims to provide a preparation method of the ganoderma spore powder buccal tablet, which is simple to operate, has low requirements on equipment and can be used for quickly manufacturing the ganoderma spore powder buccal tablet on a large scale.
The embodiment of the invention is realized by the following steps:
a ganoderma lucidum spore powder buccal tablet comprises the following components in parts by weight:
50-80 parts of ganoderma lucidum spore powder, 20-40 parts of ginseng, 10-20 parts of cordyceps sinensis, 10-20 parts of pseudo-ginseng, 5-10 parts of walnut, 5-10 parts of hawthorn, 5-10 parts of medlar, 20-40 parts of starch, 2-5 parts of flavoring agent and 2-5 parts of lubricating agent.
A preparation method of the ganoderma lucidum spore powder buccal tablet comprises the following steps:
cleaning Ginseng radix, Cordyceps, Notoginseng radix, semen Juglandis, fructus crataegi and fructus Lycii, oven drying, and grinding to obtain mixed powder;
embrittling the ganoderma lucidum spore powder at-18 to-15 ℃ for 2-3 h, and then heating to 80-85 ℃ for ultrasonic wall breaking.
Mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying to obtain stir-fried powder;
mixing the parched powder with flavoring agent and mixture, and tabletting to obtain buccal tablet containing Ganoderma spore powder.
The embodiment of the invention has the beneficial effects that:
the embodiment of the invention provides a ganoderma lucidum spore powder buccal tablet and a preparation method thereof, the ganoderma lucidum spore powder buccal tablet takes ganoderma lucidum spore powder as a main material, and is matched with various traditional Chinese medicinal materials such as ginseng, cordyceps, pseudo-ginseng, medlar and the like, and the ganoderma lucidum spore powder buccal tablet can tonify qi and blood, calm mind and improve human immunity after being taken for a long time. In addition, the walnut and the hawthorn are added to improve the taste, so that the whole ganoderma lucidum spore powder buccal tablet has better taste while keeping the drug effect, and is more beneficial to the acceptance of people. The preparation method of the ganoderma lucidum spore powder buccal tablet is simple to operate, has low requirements on equipment, and can be used for quickly manufacturing the ganoderma lucidum spore powder buccal tablet on a large scale.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The following is a detailed description of the ganoderma lucidum spore powder buccal tablet and the preparation method thereof according to the embodiment of the invention.
The embodiment of the invention provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
50-80 parts of ganoderma lucidum spore powder, 20-40 parts of ginseng, 10-20 parts of cordyceps sinensis, 10-20 parts of pseudo-ginseng, 5-10 parts of walnut, 5-10 parts of hawthorn, 5-10 parts of medlar, 20-40 parts of starch, 2-5 parts of flavoring agent and 2-5 parts of lubricating agent.
Further, the coating comprises the following components in parts by weight:
50-70 parts of ganoderma lucidum spore powder, 20-30 parts of ginseng, 10-15 parts of cordyceps sinensis, 10-15 parts of pseudo-ginseng, 5-8 parts of walnut, 5-8 parts of hawthorn, 5-8 parts of wolfberry, 20-30 parts of starch, 2-4 parts of flavoring agent and 2-4 parts of lubricating agent.
Further, the paint comprises the following components in parts by weight:
60 parts of ganoderma lucidum spore powder, 30 parts of ginseng, 13 parts of cordyceps sinensis, 13 parts of pseudo-ginseng, 6 parts of walnut, 5 parts of hawthorn, 6 parts of medlar, 25 parts of starch, 2 parts of flavoring agent and 4 parts of lubricating agent.
Wherein the flavoring agent comprises at least one of mannitol, xylitol, sucrose and glucose. The lubricant comprises at least one of stearic acid and magnesium stearate.
The ganoderma lucidum spore powder buccal tablet takes ganoderma lucidum spore powder as a main material, and is matched with various traditional Chinese medicinal materials such as ginseng, cordyceps, pseudo-ginseng, medlar and the like, so that the ganoderma lucidum spore powder buccal tablet can tonify qi and blood, calm mind and improve human immunity after being taken for a long time. In addition, the walnut and the hawthorn are added to improve the taste, so that the whole ganoderma lucidum spore powder buccal tablet has better taste while keeping the drug effect, and is more beneficial to the acceptance of people.
The embodiment also provides a preparation method of the ganoderma lucidum spore powder buccal tablet, which comprises the following steps:
s1, cleaning radix Ginseng, Cordyceps, radix Notoginseng, semen Juglandis, fructus crataegi, and fructus Lycii, oven drying, and grinding to obtain mixed powder;
s2, embrittling the ganoderma lucidum spore powder for 2-3 h at-18 to-15 ℃, and then heating to 80-85 ℃ for ultrasonic wall breaking.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
Wherein the drying temperature is 60-80 ℃, and the drying time is 30-40 min. Under the conditions, the drug effect of the traditional Chinese medicinal materials is not damaged due to high temperature, and meanwhile, higher drying efficiency can be kept.
The particle size of the mixed powder is 20-40 meshes. Within the above particle size range, the powders are more uniformly mixed, and the combination is better after the tablets are prepared, and the tablets are not easy to disintegrate.
The frequency of ultrasonic wall breaking is 25-30 kHz, and the time is 5-10 min. Under the conditions, the wall breaking efficiency is higher.
The frying time is 5-10 min. The mouth feel of the ganoderma lucidum spore powder buccal tablet can be better by frying, the frying time is not suitable for a long time, otherwise, the loss of nutrient substances is easily caused.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
50 parts of ganoderma lucidum spore powder, 40 parts of ginseng, 100 parts of cordyceps sinensis, 20 parts of pseudo-ginseng, 5 parts of walnut, 5 parts of hawthorn, 10 parts of medlar, 40 parts of starch, 2 parts of flavoring agent and 2 parts of lubricating agent.
The preparation method comprises the following steps:
s1, cleaning radix Ginseng, Cordyceps, radix Notoginseng, semen Juglandis, fructus crataegi, and fructus Lycii, oven drying at 80 deg.C for 40 min, and grinding to obtain 40 mesh mixed powder;
s2, embrittling the Ganoderma spore powder at-18 deg.C for 3 h, heating to 80 deg.C, and breaking cell wall by ultrasonic at 30 kHz for 5 min.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying for 5min to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
The Ganoderma spore powder buccal tablet has good smell and taste, and can be used for invigorating qi and blood, tranquilizing mind, improving immunity, and improving body constitution.
Example 2
The embodiment provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
80 parts of ganoderma lucidum spore powder, 20 parts of ginseng, 20 parts of cordyceps sinensis, 100 parts of pseudo-ginseng, 10 parts of walnut, 10 parts of hawthorn, 5 parts of medlar, 20 parts of starch, 5 parts of flavoring agent and 5 parts of lubricating agent.
The preparation method comprises the following steps:
s1, cleaning radix Ginseng, Cordyceps, radix Notoginseng, semen Juglandis, fructus crataegi, and fructus Lycii, oven drying at 60 deg.C for 30min, and grinding to obtain 30 mesh mixed powder;
s2, embrittling the Ganoderma spore powder at-15 deg.C for 3 h, heating to 85 deg.C, and breaking cell wall by ultrasonic wave with ultrasonic frequency of 25 kHz for 10 min.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying for 10 min to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
The Ganoderma spore powder buccal tablet has good smell and taste, and can be used for invigorating qi and blood, tranquilizing mind, improving immunity, and improving body constitution.
Example 3
The embodiment provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
70 parts of ganoderma lucidum spore powder, 40 parts of ginseng, 15 parts of cordyceps sinensis, 10 parts of pseudo-ginseng, 10 parts of walnut, 8 parts of hawthorn, 7 parts of medlar, 30 parts of starch, 4 parts of flavoring agent and 4 parts of lubricating agent.
The preparation method comprises the following steps:
s1, cleaning ginseng, cordyceps, pseudo-ginseng, walnut, hawthorn and medlar, drying for 35 min at the temperature of 60-80 ℃, and grinding to obtain mixed powder of 20 meshes;
s2, embrittling the Ganoderma spore powder at-15 deg.C for 3 h, heating to 80 deg.C, and breaking cell wall by ultrasonic wave with ultrasonic frequency of 30 kHz for 10 min.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying for 10 min to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
The Ganoderma spore powder buccal tablet has good smell and taste, and can be used for invigorating qi and blood, tranquilizing mind, improving immunity, and improving body constitution.
Example 4
The embodiment provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
60 parts of ganoderma lucidum spore powder, 25 parts of ginseng, 12 parts of cordyceps sinensis, 18 parts of pseudo-ginseng, 9 parts of walnut, 6 parts of hawthorn, 7 parts of medlar, 35 parts of starch, 4 parts of flavoring agent and 2 parts of lubricating agent.
The preparation method comprises the following steps:
s1, cleaning radix Ginseng, Cordyceps, radix Notoginseng, semen Juglandis, fructus crataegi, and fructus Lycii, oven drying at 80 deg.C for 30min, and grinding to obtain 40 mesh mixed powder;
s2, embrittling the Ganoderma spore powder at-18 deg.C for 3 h, heating to 80 deg.C, and breaking cell wall by ultrasonic at 30 kHz for 5 min.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying for 8 min to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
The Ganoderma spore powder buccal tablet has good smell and taste, and can be used for invigorating qi and blood, tranquilizing mind, improving immunity, and improving body constitution.
Example 5
The embodiment provides a ganoderma lucidum spore powder buccal tablet, which comprises the following components in parts by weight:
60 parts of ganoderma lucidum spore powder, 30 parts of ginseng, 13 parts of cordyceps sinensis, 13 parts of pseudo-ginseng, 6 parts of walnut, 5 parts of hawthorn, 6 parts of medlar, 25 parts of starch, 2 parts of flavoring agent and 4 parts of lubricating agent.
The preparation method comprises the following steps:
s1, cleaning radix Ginseng, Cordyceps, radix Notoginseng, semen Juglandis, fructus crataegi, and fructus Lycii, oven drying at 65 deg.C for 35 min, and grinding to obtain 20 mesh mixed powder;
s2, embrittling the Ganoderma spore powder at-18 deg.C for 2.5h, heating to 80 deg.C, and breaking cell wall by ultrasonic wave with ultrasonic frequency of 25 kHz for 10 min.
S3, mixing the mixed powder with the wall-broken ganoderma lucidum spore powder and starch, and stir-frying for 8 min to obtain stir-fried powder;
s4, mixing the fried powder with a flavoring agent and a mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
The Ganoderma spore powder buccal tablet has good smell and taste, and can be used for invigorating qi and blood, tranquilizing mind, improving immunity, and improving body constitution.
The embodiment of the invention provides a ganoderma lucidum spore powder buccal tablet and a preparation method thereof, the ganoderma lucidum spore powder buccal tablet takes ganoderma lucidum spore powder as a main material, and is matched with various traditional Chinese medicinal materials such as ginseng, cordyceps, pseudo-ginseng, medlar and the like, and the ganoderma lucidum spore powder buccal tablet can tonify qi and blood, calm mind and improve human immunity after being taken for a long time. In addition, the walnut and the hawthorn are added to improve the taste, so that the whole ganoderma lucidum spore powder buccal tablet has better taste while keeping the drug effect, and is more beneficial to the acceptance of people. The preparation method of the ganoderma lucidum spore powder buccal tablet is simple to operate, has low requirements on equipment, and can be used for quickly manufacturing the ganoderma lucidum spore powder buccal tablet on a large scale.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A ganoderma lucidum spore powder buccal tablet is characterized by comprising the following components in parts by weight:
50-80 parts of ganoderma lucidum spore powder, 20-40 parts of ginseng, 10-20 parts of cordyceps sinensis, 10-20 parts of pseudo-ginseng, 5-10 parts of walnut, 5-10 parts of hawthorn, 5-10 parts of medlar, 20-40 parts of starch, 2-5 parts of flavoring agent and 2-5 parts of lubricating agent.
2. The ganoderma lucidum spore powder buccal tablet according to claim 1, which is characterized by comprising the following components in parts by weight:
50-70 parts of ganoderma lucidum spore powder, 20-30 parts of ginseng, 10-15 parts of cordyceps sinensis, 10-15 parts of pseudo-ginseng, 5-8 parts of walnut, 5-8 parts of hawthorn, 5-8 parts of medlar, 20-30 parts of starch, 2-4 parts of flavoring agent and 2-4 parts of lubricant.
3. The ganoderma lucidum spore powder buccal tablet according to claim 2, which is characterized by comprising the following components in parts by weight:
60 parts of ganoderma lucidum spore powder, 30 parts of ginseng, 13 parts of cordyceps sinensis, 13 parts of pseudo-ginseng, 6 parts of walnut, 5 parts of hawthorn, 6 parts of medlar, 25 parts of starch, 2 parts of flavoring agent and 4 parts of lubricating agent.
4. The ganoderma lucidum spore powder buccal tablet according to any one of claims 1 to 3, wherein the flavoring agent comprises at least one of mannitol, xylitol, sucrose and glucose.
5. The buccal tablet of ganoderma lucidum spore powder of claim 4, wherein the lubricant comprises at least one of stearic acid and magnesium stearate.
6. A method for preparing the ganoderma lucidum spore powder buccal tablet as claimed in any one of claims 1 to 5, which comprises the following steps:
cleaning the ginseng, the cordyceps, the pseudo-ginseng, the walnut, the hawthorn and the medlar, drying, and grinding to obtain mixed powder;
embrittling the ganoderma lucidum spore powder at-18 to-15 ℃ for 2-3 h, and then heating to 80-85 ℃ for ultrasonic wall breaking;
mixing the mixed powder with the ganoderma lucidum spore powder and the starch after wall breaking, and stir-frying to obtain stir-fried powder;
and mixing the stir-fried powder with the flavoring agent and the mixing agent, and tabletting to obtain the ganoderma lucidum spore powder buccal tablet.
7. The preparation method according to claim 6, wherein the drying temperature is 60-80 ℃ and the drying time is 30-40 min.
8. The method according to claim 7, wherein the particle size of the mixed powder is 20 to 40 mesh.
9. The preparation method according to claim 8, wherein the frequency of ultrasonic wall breaking is 25-30 kHz, and the time is 5-10 min.
10. The preparation method according to claim 9, wherein the stir-frying time is 5-10 min.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113244372A (en) * | 2021-04-22 | 2021-08-13 | 建昌帮药业有限公司 | Composition for enhancing immunity and preparation process and application thereof |
| CN113577240A (en) * | 2021-09-02 | 2021-11-02 | 翔宇药业股份有限公司 | Pharmaceutical composition, preparation method and application thereof |
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2020
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113244372A (en) * | 2021-04-22 | 2021-08-13 | 建昌帮药业有限公司 | Composition for enhancing immunity and preparation process and application thereof |
| CN113577240A (en) * | 2021-09-02 | 2021-11-02 | 翔宇药业股份有限公司 | Pharmaceutical composition, preparation method and application thereof |
| CN113577240B (en) * | 2021-09-02 | 2024-01-30 | 翔宇药业股份有限公司 | Pharmaceutical composition, preparation method and application thereof |
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Application publication date: 20201215 |