CN112076123A

CN112076123A - Plant composition, plant whitening, moisturizing and freckle removing emulsion and preparation method thereof

Info

Publication number: CN112076123A
Application number: CN202011021082.XA
Authority: CN
Inventors: 王律徉
Original assignee: Guangzhou Meiwu Biotechnology Co Ltd
Current assignee: Guangzhou Meiwu Biotechnology Co Ltd
Priority date: 2020-09-24
Filing date: 2020-09-24
Publication date: 2020-12-15

Abstract

The invention discloses a plant composition, plant whitening, moisturizing and freckle removing lotion and a preparation method thereof, and belongs to the technical field of daily cosmetics. The plant composition comprises 5-20 parts of viola tricolor extract, 5-30 parts of murraya koenigii leaf extract, 1-30 parts of selaginella tamariscina extract, 2-35 parts of cuminum cyminum seed extract, 1-15 parts of artemisia apiacea leaf extract, 0.5-8 parts of lime fruit extract and 2-10 parts of eucalyptus globulus leaf extract. The seven plant extracts are compounded, so that the whitening, moisturizing and freckle removing effects on skin can be effectively enhanced, and the preparation method of the plant composition is simple and is suitable for industrial production.

Description

Plant composition, plant whitening, moisturizing and freckle removing emulsion and preparation method thereof

Technical Field

The invention belongs to the technical field of daily cosmetics, and particularly relates to a plant composition, plant whitening, moisturizing and freckle removing lotion and a preparation method thereof.

Background

Pigmentation is a common skin problem, and acne, trauma, chemical exfoliation or laser treatment inflammation may cause pigmentation, and ultraviolet irradiation may cause abnormal pigments such as chloasma, actinic freckles, and the like. Among the cosmetics sold in the market at present, moisturizing and whitening are always two most important effects of people.

Meanwhile, with the economic development and the improvement of living standard, the requirements of people on products are gradually improved, and cosmetics made of natural nontoxic components with curative effect and pertinence are attracted and favored by people.

However, some related products sold in the market have the phenomenon that the metal content exceeds the standard, and the long-term use of the products can affect the body health.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide the plant composition which is harmless and refreshing to human bodies and has the effects of whitening, moisturizing and removing freckles, the plant whitening, moisturizing and freckle-removing lotion and the preparation method thereof.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a plant composition comprises Viola tricolor extract, folium Et cacumen Murrayae extract, herba Selaginellae extract, Cuminum cyminum extract, Artemisia princeps leaf extract, Citrus aurantium fruit extract, and Eucalyptus globulus leaf extract.

The viola tricolor extract is rich in carotenoid, flavone compounds and phenolic acid components, can effectively inhibit melanin B-16 cell activity, can promote generation of aquaporin and hyaluronic acid, has the effects of whitening and moisturizing, and also has certain antibacterial capacity.

The Murraya koenigii leaf extract contains p-cymene, alpha-pinene, ocimene and other components, can inhibit the activities of tyrosinase, hyaluronidase and angiotensin converting enzyme, can eliminate p-hydroxyl free radicals, has the effects of whitening, moisturizing and resisting oxidation, and has good prevention and treatment effects on skin red blood streak.

The Cuminum cyminum seed extract contains Cuminum cyminum aldehyde, p-cymene, beta-pinene, etc., can inhibit tyrosinase activity, eliminate DPPH free radical, and has whitening, antioxidant and moisturizing effects.

The Artemisia princeps leaf extract contains volatile components such as camphene, beta-myrrh and the like and non-volatile components such as coumarin, flavonoid glycoside and the like, can eliminate DPPH free radicals, promote the proliferation of collagen and cutin protein, inhibit the activity of tyrosinase, and has the effects of activating blood, enhancing metabolism, whitening and resisting oxidation.

The fructus Citri Limoniae extract contains myrcene, camphene, ocimene, etc., and has effects of inhibiting hyaluronic acid activity and keeping moisture.

The Eucalyptus globulus Labill leaf extract contains volatile oil such as 1, 8-cineole, pinene, and bergamotene, and non-volatile components such as rutin and quercetin, and has effects of eliminating superoxide radical, inhibiting activity of melanocyte and hyaluronidase, whitening skin, keeping moisture, and resisting oxidation.

The herba Selaginellae extract contains flavone compounds, arbutin, ferulic acid, etc., has effects of eliminating superoxide radical and inhibiting melanoma B-16 cell activity, and has whitening, moisturizing and antioxidant effects in product.

Preferably, the plant composition comprises the following ingredients in parts by weight: 5-20 parts of viola tricolor extract, 5-30 parts of murraya paniculata leaf extract, 1-30 parts of selaginella tamariscina extract, 2-35 parts of cuminum cyminum seed extract, 1-15 parts of artemisia apiacea leaf extract, 0.5-8 parts of lime fruit extract and 2-10 parts of eucalyptus globulus leaf extract.

Preferably, the plant composition comprises the following ingredients in parts by weight: 18 parts of viola tricolor extract, 22 parts of murraya paniculata leaf extract, 20 parts of selaginella tamariscina extract, 22 parts of cumin seed extract, 8 parts of artemisia leaf extract, 5 parts of lime fruit extract and 5 parts of eucalyptus globulus leaf extract.

Through a plurality of experimental researches, the applicant of the invention discovers that the whitening, moisturizing and freckle removing performances of the plant composition prepared by compounding the components in the proportion can be obviously improved when the plant composition is used in plant whitening, moisturizing and freckle removing milk.

In addition, the invention discloses application of the plant composition in plant whitening, moisturizing and freckle removing milk. The plant whitening, moisturizing and freckle removing emulsion comprises a plant composition and at least one of a humectant, an antioxidant, an emulsifier, an emollient, a thickener, a preservative and essence.

Preferably, the plant whitening, moisturizing and freckle removing emulsion consists of an internal water phase, an oil phase and an external water phase, wherein the internal water phase comprises water, a preservative, essence and a plant composition; the oil phase comprises a humectant, an antioxidant, an emulsifier and an emollient; the outer aqueous phase comprises water, an emulsifier, a pH adjuster, and a thickener.

Preferably, the inner aqueous phase comprises water a, preservatives, flavours and botanical compositions; the emollient in the oil phase is rose hip oil and jojoba wax, the antioxidant is grape seed oil, the humectant is squalane and ceramide, and the emulsifier is lanolin alcohol, sorbitan oleate and polysorbate; the water in the outer water phase is water B, the emulsifier is cetearyl glucoside, and the thickener is hydroxyethyl cellulose.

Preferably, the plant whitening, moisturizing and freckle removing milk comprises the following components in parts by weight: 0.1-1 part of preservative, 01-0.5 part of essence, 1-7 parts of plant composition, 4-10 parts of rose hip oil, 2-10 parts of grape seed oil, 3-15 parts of lanolin alcohol, 1-6 parts of jojoba wax, 0.1-3 parts of squalane, 0.1-3 parts of ceramide, 0.5-5 parts of sorbitan oleate, 0.5-3 parts of polysorbate, 1-3 parts of cetearyl glucoside, 0.1-2 parts of pH regulator, 0.1-2 parts of hydroxyethyl cellulose, 15-35 parts of water A and 35-65 parts of water B.

In addition, the invention also discloses a preparation method of the plant composition, which comprises the following steps:

screening, washing, drying and grinding Viola tricolor and herba Selaginellae to obtain powder raw materials, reflux-extracting the powder raw materials with boiling water for 4-6 times, each time for 15-45min to obtain extract, concentrating the extract under normal pressure to obtain concentrated solution, and drying the concentrated solution to obtain extract;

screening, washing, drying and grinding murraya jasminorage leaves, cuminum cyminum, artemisia koenigii leaves and eucalyptus globulus leaves to obtain powder raw materials, carrying out reflux extraction on the powder raw materials for 4-6 times and 15-45min each time by using alcohol with the mass fraction of 50% to obtain extract, concentrating the extract under normal pressure to obtain concentrated solution, and drying the concentrated solution to obtain an extract;

screening, washing, drying and grinding the white lemon fruits to obtain a powdery raw material, carrying out reflux extraction on the powdery raw material for 4-6 times by using ethanol, wherein each time is 15-45min to obtain an extract, concentrating the extract under normal pressure to obtain a concentrated solution, and drying the concentrated solution to obtain an extract;

mixing the above extracts to obtain the plant composition.

Meanwhile, the invention also discloses a preparation method of the plant whitening, moisturizing and freckle removing lotion, which comprises the following steps:

(1) preparing a botanical composition;

(2) preparation of an internal aqueous phase: adding water A into a stirring pot at normal temperature, heating to 50-80 deg.C, adding the rest raw materials except antiseptic, stirring, cooling to 40-55 deg.C, and adding antiseptic to obtain inner water phase;

(3) preparing an oil phase: adding the oil phase raw materials into an emulsifying pot, heating to 70-90 ℃ to dissolve the oil phase raw materials, and stirring to obtain an oil phase;

(4) preparing an external water phase: adding water B into a stirring pot at normal temperature, heating to 40-60 ℃, stirring, and adding the other water phase raw materials except the pH regulator;

(5) dripping the inner water phase into the oil phase, emulsifying for 30-60min, and stirring to obtain emulsion A;

(6) at 30-50 ℃, dropwise adding the emulsion A into an external water phase for emulsification;

(7) and (3) regulating the pH value by using a pH regulator, and uniformly stirring to obtain the plant whitening, moisturizing and freckle removing milk.

Preferably, in the step (5), the emulsification temperature is 60-75 ℃, and the stirring speed is 600-1500 rpm; in the step (6), the emulsifying time is 20-35min, and the stirring speed is 300-800 rpm.

Compared with the prior art, the invention has the beneficial effects that: according to the invention, the components of various plant extracts are analyzed, the proportion of the plant extracts and the preparation process of the plant whitening, moisturizing and freckle removing lotion are adjusted, and the lotion with whitening, antioxidant, freckle removing and powerful moisturizing effects is finally prepared.

Detailed Description

To better illustrate the objects, technical solutions and advantages of the present invention, the present invention will be further described with reference to specific examples (unless otherwise specified, the amounts used in the examples and comparative examples of the present invention are in parts by weight, and each part by weight in the examples and comparative examples corresponds to the same mass).

Example 1

The invention discloses an embodiment of a plant whitening, moisturizing and freckle removing milk, which comprises the following formula:

0.5 part of preservative, 0.5 part of essence, 5 parts of botanical composition, 7 parts of rose hip oil, 6 parts of grape seed oil, 9 parts of lanolin alcohol, 4 parts of jojoba wax, 3 parts of squalane, 3 parts of ceramide, 3 parts of sorbitan oleate, 1.5 parts of polysorbate, 2 parts of cetearyl glucoside, 1 part of pH regulator, 1 part of hydroxyethyl cellulose, 18.5 parts of water A and 35 parts of water B. Wherein the formulation of the botanical composition is shown in table 1.

The preparation method of the plant whitening, moisturizing and freckle removing milk comprises the following steps:

(1) preparing a plant composition: screening, washing, drying and grinding Viola tricolor and herba Selaginellae to obtain powder raw materials, reflux-extracting the powder raw materials with boiling water for 5 times (30 min each time) to obtain extract, concentrating the extract under normal pressure to obtain concentrated solution, and drying the concentrated solution to obtain extract;

screening, washing, drying and grinding murraya jasminorage leaves, cuminum cyminum, artemisia koenigii leaves and eucalyptus globulus leaves to obtain powder raw materials, carrying out reflux extraction on the powder raw materials for 5 times and 30min each time by using 50% ethanol by mass to obtain an extract, concentrating the extract under normal pressure to obtain a concentrated solution, and drying the concentrated solution to obtain an extract;

screening, washing, drying and grinding the white lemon fruits to obtain a powdery raw material, carrying out reflux extraction on the powdery raw material for 5 times and 30min each time to obtain an extract, concentrating the extract at normal pressure to obtain a concentrated solution, and drying the concentrated solution to obtain an extract;

mixing the above extracts to obtain the plant composition;

(2) preparation of an internal aqueous phase: adding water A into a stirring pot at normal temperature, heating to 70 ℃, adding the other raw materials of the inner water phase except the preservative, stirring, cooling to 50 ℃, and adding the preservative to obtain an inner water phase;

(3) preparing an oil phase: adding the oil phase raw materials into an emulsifying pot, heating to 80 ℃ to dissolve the oil phase raw materials, and stirring to obtain an oil phase;

(4) preparing an external water phase: adding water B into a stirring pot at normal temperature, heating to 50 ℃, stirring, and adding the other water phase raw materials except the pH regulator;

(5) dripping the inner water phase into the oil phase, emulsifying at 70 deg.C for 40min, and stirring at 1200rpm to obtain emulsion A;

(6) dropwise adding the emulsion A into the external water phase at 40 deg.C, and emulsifying for 30 min;

(7) and (3) adjusting the pH value by using a pH regulator, stirring at the rotating speed of 700rpm, and uniformly stirring to obtain the plant whitening, moisturizing and freckle-removing milk.

Example 2

According to an embodiment of the plant whitening, moisturizing and freckle-removing lotion, the formula of the plant whitening, moisturizing and freckle-removing lotion is the same as that of the embodiment 1 except that the formula of the plant composition is different from that of the embodiment 1. The formulation of the plant composition is shown in table 1.

The preparation method of the plant whitening, moisturizing and freckle removing milk is the same as that of the embodiment 1.

Example 3

Example 4

1 part preservative, 0.2 part essence, 1 part botanical composition, 4 parts rose hip oil, 2 parts grape seed oil, 13 parts lanolin alcohol, 6 parts jojoba wax, 0.1 part squalane, 0.1 part ceramide, 0.5 part sorbitan oleate, 0.5 part polysorbate, 3 parts cetearyl glucoside, 2 parts pH adjusting agent, 2 parts hydroxyethyl cellulose, 26.6 parts water a, and 38 parts water B. In this example, the formulation of the plant composition is shown in table 1.

Example 5

0.1 part of preservative, 0.1 part of essence, 7 parts of botanical composition, 10 parts of rose hip oil, 10 parts of grape seed oil, 3 parts of lanolin alcohol, 1 part of jojoba wax, 1 part of squalane, 1 part of ceramide, 5 parts of sorbitan oleate, 3 parts of polysorbate, 1 part of cetearyl glucoside, 0.1 part of pH regulator, 0.1 part of hydroxyethyl cellulose, 21 parts of water A and 36.6 parts of water B. In this example, the formulation of the plant composition is shown in table 1.

Comparative examples 1 to 7

Comparative examples 1 to 7 are all plant whitening, moisturizing and freckle removing milks, except that the formula of the plant composition is different from that of example 1, the other formulas are the same as that of example 1, and the formula of the plant composition is shown in table 1.

The preparation method of the plant whitening, moisturizing and freckle removing milk is basically the same as that of the embodiment 1.

TABLE 1 plant composition recipe (parts by weight)

Performance testing

1) Safety test

Human skin patch tests were performed on examples 1 to 5 with reference to "cosmetic hygiene standards". 150 healthy, allergy-free volunteers 18-60 years old were selected as subjects, which were divided into 5 groups of 30 persons each, and no other skin care products were used during the trial. Selecting a spot tester with an area of 6mm multiplied by 6mm, putting a test object into a small chamber of the spot tester, wherein the dosage is 0.025g, sticking the spot tester with the test object on the back of a subject by using a hypoallergenic adhesive tape, and lightly pressing the spot tester with a palm to uniformly stick the spot tester on the skin for 24 hours. The skin reactions were observed at 30min (after the indentation disappeared), 24h, and 48h after the test article plaque removal, respectively, according to the standards shown in table 2, and the observation results were recorded, with the safety test results shown in table 3.

TABLE 2 skin response grading Standard for skin Enclosed Patch test

TABLE 3 safety test results

As can be seen from Table 3, after the patch test for 48 hours, the safety test score of the plant whitening, moisturizing and freckle removing cream in the examples 1-5 is still 0, which indicates that the skin whitening, moisturizing and freckle removing cream is safe and non-irritant to skin.

2) Whitening efficacy test

Whitening efficacy was tested in examples 1 to 5 and comparative examples 1 to 7, and the whitening efficacy was characterized by tyrosinase activity inhibition. Preparing 1.5g/L levodopa by 0.01mol/L phosphate buffer solution with pH of 6.8, adding 40 mu L levodopa into a 96-well plate, adding 80 mu L phosphate buffer solution and 40mg test substance mask, adding 40 mu L100U/mL tyrosinase, mixing uniformly, reacting in 30 ℃ water bath for 30min, measuring absorbance at 490nm, using 40 mu L phosphate buffer solution as blank control, and calculating the tyrosinase activity inhibition rate according to the following formula.

Inhibition rate ═ 1- (T)₁-T₂)/(C₁-C₂)]×100％

In the formula C₁Absorbance when no enzyme was added to the sample, C₂Absorbance without enzyme and without sample, T₁Is the absorbance, T, at the time of addition of enzyme to the sample₂Absorbance without enzyme plus sample. The test results are shown in table 4.

TABLE 4 tyrosinase activity inhibition ratio (%)

As can be seen from Table 4, the inhibition ratios of examples 1 to 5 on tyrosinase activity are greatly different from those of comparative examples 1 to 7, and the inhibition ratios of examples 1 to 5 on tyrosinase activity are generally higher, which indicates that the skin whitening cream has a better melanin production inhibition effect, i.e., a better skin whitening effect.

3) Moisture retention test

The moisture retention tests of examples 1 to 5 and comparative examples 1 to 7 were performed with reference to "guidelines for evaluating moisturizing efficacy of cosmetics", 60 volunteers between 18 and 30 years old were selected as test subjects, the test subjects were divided into 12 groups of 5 subjects, each group was cleaned with facial cleanser, air-dried naturally, the symmetrical positions of the left and right faces were marked out with 4cm by 4cm areas, and the test samples were measured at 2mg/cm²The dosage of the test substance is measured by a single smearing of a latex finger stall and a Corneometer CM825, the test is carried out once before the use of the sample and once 15min, 2h and 4h after the use of the sample, each area is parallelly measured for 3 times, the average value is taken, and the test result is shown in Table 5.

TABLE 5 moisture retention test results

As can be seen from Table 5, the moisture increase rates of the examples 1 to 5 are obviously superior to those of the comparative examples 1 to 7, and the moisture retention performance of the mask can be synergistically improved by compounding the plant extracts disclosed by the invention.

4) Spot removal Performance test

120 volunteers with obvious skin color spots are selected and averagely divided into 12 groups, 10 persons in each group and 12 persons in each group use the plant whitening, moisturizing and freckle removing lotion disclosed in examples 1-5 and comparative examples 1-7 respectively for 1 month, the lotion is used once in the morning and evening, the amount of about 1 coin is used each time, the facial color spot condition of the volunteers after 1 month is recorded, and the results are shown in table 6.

TABLE 6 speckle removing Performance test results

As can be seen from Table 6, in the volunteers using the compositions in examples 1 to 5, the number of the color spots of each group is obviously reduced, and the number of the color spots is obviously reduced, but the total number of the unapparent people is higher than that of the volunteers in comparative examples 1 to 7, which shows that the whitening, moisturizing and freckle-removing milk prepared from the plant composition disclosed by the invention has better freckle-removing performance.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. A plant composition comprises Viola tricolor extract, folium Et cacumen Murrayae extract, herba Selaginellae extract, Cuminum cyminum extract, Artemisia princeps extract, Citrus aurantium fruit extract, and Eucalyptus globulus leaf extract.

2. The plant composition of claim 1, wherein the plant composition comprises the following ingredients in parts by weight: 5-20 parts of viola tricolor extract, 5-30 parts of murraya paniculata leaf extract, 1-30 parts of selaginella tamariscina extract, 2-35 parts of cuminum cyminum seed extract, 1-15 parts of artemisia apiacea leaf extract, 0.5-8 parts of lime fruit extract and 2-10 parts of eucalyptus globulus leaf extract.

3. The plant composition of claim 2, wherein the plant composition comprises the following ingredients in parts by weight: 18 parts of viola tricolor extract, 22 parts of murraya paniculata leaf extract, 20 parts of selaginella tamariscina extract, 22 parts of cumin seed extract, 8 parts of artemisia leaf extract, 5 parts of lime fruit extract and 5 parts of eucalyptus globulus leaf extract.

4. The application of the plant composition as claimed in any one of claims 1 to 3, wherein the composition can be used for preparing plant whitening, moisturizing and freckle removing milk.

5. The plant whitening, moisturizing and freckle removing lotion containing the plant composition according to any one of claims 1 to 3, wherein the plant whitening, moisturizing and freckle removing lotion further contains at least one of a humectant, an antioxidant, an emulsifier, a thickener, a preservative, an emollient and an essence.

6. The plant whitening, moisturizing and freckle removing milk according to claim 5, wherein the plant whitening, moisturizing and freckle removing milk consists of an internal water phase, an oil phase and an external water phase, wherein the internal water phase comprises water, a preservative, essence and a plant composition; the oil phase comprises a humectant, an antioxidant, an emulsifier and an emollient; the outer aqueous phase comprises water, an emulsifier, a pH adjuster, and a thickener.

7. The plant whitening, moisturizing and spot removing lotion according to claim 6, wherein the internal aqueous phase comprises water A, a preservative, a perfume and a plant composition; the emollient in the oil phase is rose hip oil and jojoba wax, the antioxidant is grape seed oil, the humectant is squalane and ceramide, and the emulsifier is lanolin alcohol, sorbitan oleate and polysorbate; the water in the outer water phase is water B, the emulsifier is cetearyl glucoside, and the thickener is hydroxyethyl cellulose.

8. The plant whitening, moisturizing and freckle removing milk according to claim 7, which is prepared from the following components in parts by weight: 0.1-1 part of preservative, 0.1-0.5 part of essence, 1-7 parts of plant composition, 4-10 parts of rose hip oil, 2-10 parts of grape seed oil, 3-15 parts of lanolin alcohol, 1-6 parts of jojoba wax, 0.1-3 parts of squalane, 0.1-3 parts of ceramide, 0.5-5 parts of sorbitan oleate, 0.5-3 parts of polysorbate, 1-3 parts of cetearyl glucoside, 0.1-2 parts of pH regulator, 0.1-2 parts of hydroxyethyl cellulose, 15-35 parts of water A and 35-65 parts of water B.

9. A method of preparing a botanical composition as claimed in any of claims 1 to 3, characterized in that the method comprises:

mixing the above extracts to obtain the plant composition.

10. A preparation method of the plant whitening, moisturizing and freckle removing milk according to any one of claims 7 to 8, characterized by comprising the following steps:

(1) preparing a botanical composition;