CN112075639A - Composite polypeptide powder capable of enhancing immunity and preparation method thereof - Google Patents
Composite polypeptide powder capable of enhancing immunity and preparation method thereof Download PDFInfo
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- CN112075639A CN112075639A CN201910516555.4A CN201910516555A CN112075639A CN 112075639 A CN112075639 A CN 112075639A CN 201910516555 A CN201910516555 A CN 201910516555A CN 112075639 A CN112075639 A CN 112075639A
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- 239000000843 powder Substances 0.000 title claims abstract description 72
- 230000036039 immunity Effects 0.000 title claims abstract description 51
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 51
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 51
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 48
- 239000002131 composite material Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title abstract description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 63
- 244000068988 Glycine max Species 0.000 claims abstract description 28
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- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims abstract description 21
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- 235000011090 malic acid Nutrition 0.000 claims abstract description 21
- 239000001630 malic acid Substances 0.000 claims abstract description 21
- 239000001509 sodium citrate Substances 0.000 claims abstract description 21
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 21
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- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims abstract description 21
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- 239000004475 Arginine Substances 0.000 description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
- 235000010208 anthocyanin Nutrition 0.000 description 2
- 229930002877 anthocyanin Natural products 0.000 description 2
- 239000004410 anthocyanin Substances 0.000 description 2
- 150000004636 anthocyanins Chemical class 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
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- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 2
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- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
- A23P10/47—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added using additives, e.g. emulsifiers, wetting agents or dust-binding agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention discloses composite polypeptide powder capable of enhancing immunity and a preparation method thereof, wherein the composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 2-4 parts of aronia melanocarpa concentrated powder, 60-90 parts of inulin, 0.5-3 parts of corn peptide, 10-20 parts of soybean peptide, 0.3-0.7 part of stevioside, 0.05-0.1 part of sucralose, 3-5 parts of citric acid, 1-2 parts of malic acid and 0.1-0.2 part of sodium citrate. The composite polypeptide powder capable of enhancing immunity has the effects of enhancing immunity and resisting fatigue, and is widely suitable for various crowds; the preparation method of the composite polypeptide powder capable of enhancing immunity, disclosed by the invention, is simple in process and suitable for large-scale industrial production, and the prepared composite polypeptide powder is good in health-care effect and has a good application prospect.
Description
Technical Field
The invention relates to the technical field of health care medicines, in particular to composite polypeptide powder capable of enhancing immunity and a preparation method thereof.
Background
In recent years, scientific research shows that the small molecular peptide as a functional active fragment of protein not only has higher nutritive value than protein, can provide nutrient substances required by the growth and development of human body, but also has unique physiological activity which many proteins do not have. The peptide is in the form of life existence, and the renewal, metabolism, growth and repair of cells can not be separated from the peptide, so that the peptide is applied to various health foods, and can rapidly enhance, activate and repair low immune function, degraded immune function and immune dysfunction.
The soybean peptide is also called soybean polypeptide, is an enzymolysis product of soybean protein, and is usually a peptide mixture consisting of 3-6 amino acids, and the molecular weight of the soybean peptide is mainly concentrated below 1000. The soybean peptide contains arginine and glutamic acid. Glutamate can produce immune cells, and can repel viruses. Arginine can increase the size and health degree of thymus, an important immune organ of a human body, and enhance the immunity. The soybean peptide is absorbed by the intestinal tract much faster than protein and amino acid, and has important functions of obtaining sufficient amino acid source for human body, rapidly repairing damaged muscle and eliminating fatigue.
The corn peptide is a small molecular polypeptide substance obtained by directional enzyme digestion and a specific small peptide separation technology of protein extracted from corn. The content of glutamine in the composition of the corn peptide amino acid is very high, and the glutamine is closely related to tissue growth and repair, and has important values in improving the immunity of the organism, maintaining the normal structure and function of intestinal mucosa and improving the capability of the organism to adapt to external harmful stimulation.
The Aronia melanocarpa fruit, commonly known as Aronia melanocarpa, belongs to Aronia adenophora of Maloideae of Rosaceae. Aronia melanocarpa berries are one of the most abundant plants of anthocyanin and have extremely strong free radical scavenging activity of antioxidants. The Aronia melanocarpa anthocyanin can activate immune system, prevent serum immunoglobulin from being invaded by free radicals, activate macrophage and enhance human immunity.
In the prior art, no special medicine is available for organically combining the beneficial components to prepare the tabletting candy which has comprehensive nutritional value and outstanding efficacy and is convenient to eat.
Disclosure of Invention
The invention aims to overcome the defects, provides the composite polypeptide powder capable of enhancing the immunity, has the effects of enhancing the immunity and resisting fatigue, and is widely suitable for various crowds; in addition, the invention also provides a preparation method of the composite polypeptide powder capable of enhancing immunity, the process is simple, the composite polypeptide powder is suitable for large-scale industrial production, and the prepared composite polypeptide powder has a good health-care effect and a good application prospect.
In order to achieve the purpose, the invention provides composite polypeptide powder capable of enhancing immunity in a first aspect, which comprises the following raw materials in parts by weight: 2-4 parts of aronia melanocarpa concentrated powder, 60-90 parts of inulin, 0.5-3 parts of corn peptide, 10-20 parts of soybean peptide, 0.3-0.7 part of stevioside, 0.05-0.1 part of sucralose, 3-5 parts of citric acid, 1-2 parts of malic acid and 0.1-0.2 part of sodium citrate.
Furthermore, the preferable raw materials for preparing the composite polypeptide powder capable of enhancing immunity of the invention comprise the following components in parts by weight: 2.5 parts of aronia melanocarpa concentrated powder, 76 parts of inulin, 1 part of corn peptide, 12 parts of soybean peptide, 0.4 part of stevioside, 0.08 part of sucralose, 3.5 parts of citric acid, 1.8 parts of malic acid and 0.18 part of sodium citrate.
Furthermore, the preferable raw materials for preparing the composite polypeptide powder capable of enhancing immunity of the invention comprise the following components in parts by weight: the material comprises the following raw materials in percentage by mass: 3.5 parts of aronia melanocarpa concentrated powder, 60-90 parts of inulin, 2 parts of corn peptide, 18 parts of soybean peptide, 0.6 part of stevioside, 0.06 part of sucralose, 4.5 parts of citric acid, 1.2 parts of malic acid and 0.12 part of sodium citrate.
The invention provides a preparation method of composite polypeptide powder capable of enhancing immunity, which comprises the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 20-30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 10-20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 50-65 ℃, and the drying is stopped when the water content is tested to be 3-5 parts;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Compared with the prior art, the invention has the beneficial effects that:
1. the composite polypeptide powder capable of enhancing immunity has the effects of enhancing immunity and resisting fatigue, and is widely suitable for various crowds; the soybean peptide, the corn peptide and the aronia melanocarpa concentrated powder are main raw materials in the composite polypeptide powder capable of enhancing the immunity, and the immunity enhancing and anti-fatigue effects of the composite polypeptide powder are optimal through the synergistic effect among the soybean peptide, the corn peptide and the aronia melanocarpa concentrated powder and the scientific compatibility among the raw materials.
2. The preparation method of the composite polypeptide powder capable of enhancing immunity, disclosed by the invention, is simple in process and suitable for large-scale industrial production, and the prepared composite polypeptide powder is good in health-care effect and has a good application prospect.
3. According to the preparation method of the composite polypeptide powder capable of enhancing immunity, ethanol with the volume fraction of 80% is used as a solvent, so that the drying time in the step S3 can be greatly reduced, and the production cost of the composite polypeptide powder is reduced.
Drawings
FIG. 1 is a schematic flow chart of a method for preparing a composite polypeptide powder capable of enhancing immunity according to the present invention.
Detailed Description
In order to make the technical means, the characteristics, the purposes and the functions of the invention easy to understand, the invention is further described with reference to the specific drawings.
Example 1
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 2g of aronia melanocarpa concentrated powder, 65g of inulin, 0.6g of corn peptide, 12g of soybean peptide, 0.3g of stevioside, 0.05g of sucralose, 3.1g of citric acid, 1g of malic acid and 0.1g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 25 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 150 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 60 ℃, and the drying is stopped when the water content is 3g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Example 2
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 4g of aronia melanocarpa concentrated powder, 75g of inulin, 2.8g of corn peptide, 20g of soybean peptide, 0.5g of stevioside, 0.1g of sucralose, 4g of citric acid, 2g of malic acid and 0.2g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 200 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 60 ℃, and the drying is stopped when the water content is 3g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Example 3
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 2.5g of aronia melanocarpa concentrated powder, 76g of inulin, 1g of corn peptide, 12g of soybean peptide, 0.4g of stevioside, 0.08g of sucralose, 3.5g of citric acid, 1.8g of malic acid and 0.18g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 28 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 60 ℃, and the drying is stopped when the water content is 3g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Example 4
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 3.5g of aronia melanocarpa concentrated powder, 65g of inulin, 2g of corn peptide, 18g of soybean peptide, 0.6g of stevioside, 0.06g of sucralose, 4.5g of citric acid, 1.2g of malic acid and 0.12g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 20-30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 10-20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 50-65 ℃, and the drying is stopped when the water content is 3-5 g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Example 5
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 3.5g of aronia melanocarpa concentrated powder, 90g of inulin, 2g of corn peptide, 18g of soybean peptide, 0.6g of stevioside, 0.06g of sucralose, 4.5g of citric acid, 1.2g of malic acid and 0.12g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 20-30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 10-20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 50-65 ℃, and the drying is stopped when the water content is 3-5 g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
Example 6
The composite polypeptide powder capable of enhancing immunity comprises the following raw materials in parts by weight: 3.5g of aronia melanocarpa concentrated powder, 80g of inulin, 2g of corn peptide, 18g of soybean peptide, 0.6g of stevioside, 0.06g of sucralose, 4.5g of citric acid, 1.2g of malic acid and 0.12g of sodium citrate.
Referring to fig. 1, the preparation method of the composite polypeptide powder capable of enhancing immunity in this embodiment includes the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 20-30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 10-20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 50-65 ℃, and the drying is stopped when the water content is 3-5 g in the test;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
The composite polypeptide powder capable of enhancing immunity, which is prepared by the invention, has the effects of enhancing immunity and resisting fatigue, is widely suitable for various crowds, is simple in preparation method, is suitable for large-scale industrial production, and has a good application prospect.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. The composite polypeptide powder capable of enhancing immunity is characterized by comprising the following raw materials in parts by weight: 2-4 parts of aronia melanocarpa concentrated powder, 60-90 parts of inulin, 0.5-3 parts of corn peptide, 10-20 parts of soybean peptide, 0.3-0.7 part of stevioside, 0.05-0.1 part of sucralose, 3-5 parts of citric acid, 1-2 parts of malic acid and 0.1-0.2 part of sodium citrate.
2. The compound polypeptide powder capable of enhancing immunity as claimed in claim 1, which comprises the following raw materials in parts by weight: 2.5 parts of aronia melanocarpa concentrated powder, 76 parts of inulin, 1 part of corn peptide, 12 parts of soybean peptide, 0.4 part of stevioside, 0.08 part of sucralose, 3.5 parts of citric acid, 1.8 parts of malic acid and 0.18 part of sodium citrate.
3. The compound polypeptide powder capable of enhancing immunity as claimed in claim 1, which comprises the following raw materials in parts by weight: 3.5 parts of aronia melanocarpa concentrated powder, 60-90 parts of inulin, 2 parts of corn peptide, 18 parts of soybean peptide, 0.6 part of stevioside, 0.06 part of sucralose, 4.5 parts of citric acid, 1.2 parts of malic acid and 0.12 part of sodium citrate.
4. The method for preparing the composite polypeptide powder capable of enhancing immunity according to any one of claims 1 to 3, comprising the following steps:
s1, sequentially putting the aronia melanocarpa concentrated powder, inulin, corn peptide, soybean peptide, stevioside, sucralose, citric acid, malic acid and sodium citrate into a stirring pot, and stirring and mixing for 20-30 minutes;
s2, adding 80% ethanol by volume fraction into the stirring pot in the step S1, continuously stirring for 10-20 minutes, and then sending the mixture to a granulator for granulation;
s3, conveying the particles manufactured by the granulator in the step S2 into a drying oven for drying, wherein the drying temperature is 50-65 ℃, and the drying is stopped when the water content is tested to be 3-5 parts;
s4, sieving the dried particles obtained in the step S4 by using a 80-mesh sieve, and packaging to obtain the compound polypeptide powder capable of enhancing the immunity.
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CN114081186A (en) * | 2022-01-20 | 2022-02-25 | 南京浩明乳业有限责任公司 | Oligomeric polypeptide powder and processing technology thereof |
CN116114871A (en) * | 2023-01-31 | 2023-05-16 | 山东健奕宏生物制药有限公司 | Chinese health-preserving composition for enhancing immunity and preparation method and application thereof |
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CN108077522A (en) * | 2017-12-28 | 2018-05-29 | 天津科技大学 | A kind of compound pressed candy of Black Box Tracing and preparation method thereof |
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CN108077522A (en) * | 2017-12-28 | 2018-05-29 | 天津科技大学 | A kind of compound pressed candy of Black Box Tracing and preparation method thereof |
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