CN111995541A - 含有稳定重同位素的酰胺官能团的化合物及其应用 - Google Patents
含有稳定重同位素的酰胺官能团的化合物及其应用 Download PDFInfo
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- CN111995541A CN111995541A CN201910447749.3A CN201910447749A CN111995541A CN 111995541 A CN111995541 A CN 111995541A CN 201910447749 A CN201910447749 A CN 201910447749A CN 111995541 A CN111995541 A CN 111995541A
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
参数 | 单位 | 化合物1 | Alpelisib |
AUC<sub>0-t</sub> | ug/L*h | 28719 | 26405 |
AUC<sub>0-∞</sub> | ug/L*h | 28798 | 26476 |
Tmax | H | 3 | 3 |
Vz/F | L/kg | 1.655 | 1.798 |
CLz/F | L/h/kg | 0.434 | 0.472 |
Cmax | ug/L | 2390 | 2297 |
参数 | 单位 | 化合物1 | Alpelisib |
AUC(0-t) | ug/L*h | 27845 | 26212 |
AUC(0-∞) | ug/L*h | 32554 | 30597 |
Tmax | h | 2 | 2 |
Vz/F | L/kg | 2.236 | 2.37 |
CLz/F | L/h/kg | 0.384 | 0.409 |
Cmax | ug/L | 4519 | 4208 |
Claims (20)
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CN113651768A (zh) * | 2021-03-24 | 2021-11-16 | 南华大学 | 一种n-芳基邻氨基苯甲酰胺类化合物及其制备和应用 |
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CN113651768A (zh) * | 2021-03-24 | 2021-11-16 | 南华大学 | 一种n-芳基邻氨基苯甲酰胺类化合物及其制备和应用 |
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