CN111925930A

CN111925930A - Virus detector

Info

Publication number: CN111925930A
Application number: CN202010791441.3A
Authority: CN
Inventors: 单洪瑞; 戴海浪; 陈险峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-08-07
Filing date: 2020-08-07
Publication date: 2020-11-13
Anticipated expiration: 2040-08-07
Also published as: CN111925930B

Abstract

A virus detector can detect a reaction tube loaded with a sample, and comprises a shell, a sample rack, a detection rack, a heating device, an excitation light source, a detection mechanism and a control unit; the shell is provided with a detection cavity and an opening for communicating the detection cavity with the outside; the sample rack is used for loading the reaction tube, and the sample rack can be arranged in the detection cavity; the detection mechanism comprises an enclosing piece and a detection unit, a detection groove is formed in the enclosing piece, the detection unit is arranged in the detection groove and is electrically connected with the control unit, and the enclosing piece is arranged in the detection cavity in a lifting mode; the surrounding piece can be lifted, the lower part of the reaction tube is placed in the detection groove, and the detection groove surrounds the lower part of the reaction tube, so that the detection unit can isolate most of the influence of stray light when detecting the reaction tube.

Description

Virus detector

Technical Field

The invention relates to the field of virus detection, in particular to a virus detector.

Background

At present, the virus detection mode mainly aims at the detection of virus nucleic acid, wherein the detection of the virus nucleic acid by using a fluorescent PCR detector is a relatively quick and accurate detection mode, the technology can realize the quantitative analysis of a virus DNA template, and has important significance for molecular biology research, medical research and the like. The existing fluorescent PCR instrument has the following defects: when the fluorescence intensity of the detection sample is detected, the fluorescence intensity is easily interfered by other stray light, so that the detection result has errors.

Disclosure of Invention

Technical problem to be solved

The virus detector provided by the invention can effectively solve the problems.

(II) technical scheme

In order to achieve the purpose, the invention provides the following technical scheme: a virus detector can detect a reaction tube loaded with a sample, and comprises a shell, a sample rack, a detection rack, a heating device, an excitation light source, a detection mechanism and a control unit; the shell is provided with a detection cavity and an opening for communicating the detection cavity with the outside, the heating device is arranged in the shell and is electrically connected with the control unit, and the heating device can heat the detection cavity; the sample rack is used for loading the reaction tube, and the sample rack can be arranged in the detection cavity; the detection frame is connected with the shell in a sliding way and can cover the opening; the excitation light source is arranged in the detection cavity and is electrically connected with the control unit; the detection mechanism comprises an enclosing piece and a detection unit, wherein a detection groove is formed in the enclosing piece, the detection unit is arranged in the detection groove and is electrically connected with the control unit, a lifting groove communicated with the detection cavity is further formed in the shell, and the enclosing piece is arranged in the lifting groove in a lifting manner; the heating device can heat the detection cavity so as to heat the reaction tube in the detection cavity; the excitation light source can irradiate the reaction tube; the surrounding member may be raised and the lower portion of the reaction tube may be placed in the detection bath so that the detection unit may detect the reaction tube.

Preferably, the sample holder may be loaded with a plurality of reaction tubes, the enclosure may be provided with a plurality of detection grooves and a plurality of corresponding detection units, and the plurality of reaction tubes may be respectively inserted into the plurality of detection grooves.

Preferably, the virus detector further comprises a bearing frame, the bearing frame is used for installing the sample frame, the bearing frame is fixedly installed on the detection frame, and the bearing frame is placed in the detection cavity when the detection frame covers the opening.

Preferably, the detection frame includes upper cover plate and many lifter, the equal fixed connection of one end of many lifter on the upper cover plate, many lifter other ends all can stretch into the detection intracavity and with shell sliding connection, accept frame fixed connection on the lifter.

Preferably, the virus detector further comprises a rotating part and a pressing plate, the rotating part is rotatably connected with the pressing plate, the lifting rods penetrate through the pressing plate and are in sliding connection with the pressing plate, and the pressing plate is arranged above the bearing frame; one of the lifting rods is also provided with threads and can be in threaded connection with the rotating piece, and the rotating piece can enable the pressing plate to slide along the lifting rod.

Preferably, the virus detector further comprises a rotary cover, the rotary cover is rotatably connected with the upper cover plate, a clamping boss is further arranged on the side edge of the rotary cover, a clamping groove communicated with the opening and the detection cavity is further formed in the shell, and the clamping boss can slide in the clamping groove.

Preferably, the virus detector further comprises a first filter, an annular groove is formed in the bottom of the detection cavity, the excitation light source is annularly distributed in the annular groove, the first filter is mounted at the groove opening of the annular groove and covers the excitation light source, and the irradiation direction of the excitation light source is obliquely and upwards arranged.

Preferably, the virus detector further comprises a second filter, the surrounding part comprises an upper part and a lower part, the lower part is arranged in the lifting groove in a lifting manner, and the upper part is detachably connected to the top of the lower part; the detection groove comprises a first groove and a second groove which are communicated with each other, the first groove is arranged in the upper part, the second groove is arranged in the lower part, the detection unit is arranged at the groove bottom of the second groove, and the second filter is arranged at the top of the second groove.

Preferably, the virus detector further comprises a first air extractor and a second air extractor, the housing is further provided with an air inlet and an air outlet, the first air extractor and the second air extractor are both installed in the detection cavity and are respectively communicated with the air inlet and the air outlet, and the first air extractor and the second air extractor are both electrically connected with the control unit.

Preferably, this virus detector still includes support frame and many spinal branchs vaulting pole, and the sample frame mountable still is equipped with the groove of accomodating at the shell top on the support frame, and the one end of many spinal branchs vaulting pole all is articulated with the support frame, and the other end all articulates in accomodating the inslot to make the support frame can swing and accomodate to accomodating the inslot.

Advantageous effects

The invention has the beneficial effects that: a virus detector can detect a reaction tube loaded with a sample, and comprises a shell, a sample rack, a detection rack, a heating device, an excitation light source, a detection mechanism and a control unit; the shell is provided with a detection cavity and an opening for communicating the detection cavity with the outside; the sample rack is used for loading the reaction tube, and the sample rack can be arranged in the detection cavity; the detection mechanism comprises an enclosing piece and a detection unit, a detection groove is formed in the enclosing piece, the detection unit is arranged in the detection groove and is electrically connected with the control unit, and the enclosing piece is arranged in the detection cavity in a lifting mode; the surrounding piece can be lifted, the lower part of the reaction tube is placed in the detection groove, and the detection groove surrounds the lower part of the reaction tube, so that the detection unit can isolate most of the influence of stray light when detecting the reaction tube.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention without limiting the invention in which:

FIG. 1 is a schematic illustration of an explosive assembly configuration according to an embodiment of the present invention;

FIG. 2 is a first overall structure diagram of the embodiment of the present invention;

FIG. 3 is a schematic overall structure diagram of the second embodiment of the present invention;

FIG. 4 is a third schematic view of the overall structure of the embodiment of the present invention;

FIG. 5 is a first partial schematic structural diagram of an embodiment of the present invention;

FIG. 6 is a second partial schematic structural diagram according to an embodiment of the present invention;

FIG. 7 is an enlarged view taken at A in FIG. 6;

FIG. 8 is a first schematic view of the structure in the detection chamber;

FIG. 9 is a second schematic structural view of the detection chamber;

FIG. 10 is a first schematic structural view of a testing stand;

FIG. 11 is a second schematic structural view of the testing stand;

FIG. 12 is a first schematic structural view of a detecting mechanism;

FIG. 13 is a second schematic structural view of the detecting mechanism;

FIG. 14 is a first schematic structural view of the support frame and the support rod;

FIG. 15 is a second schematic structural view of the support frame and the support rod;

in the figure, 1 a shell, 2a sample rack, 3a detection rack, 4a heating device, 5 an excitation light source, 6a detection mechanism, 7a bearing rack, a reaction tube a, a detection groove b, a control unit c, a driving unit d, a first groove b1, a second groove b2, a detection cavity 10, an opening 11, a lifting groove 12, a clamping groove 13, an annular groove 14, an air inlet 15, an air outlet 16, a receiving groove 17, an upper cover plate 30, a lifting rod 31, an elastic resetting piece 32, a rotating piece 33, a pressing plate 34, a rotary cover 35, a clamping boss 350, a surrounding piece 60, a detection unit 61, an upper piece 601, a lower piece 602, a2 first filter, a3 second filter, a4 first air suction device, a5 second air suction device, a6 supporting rack, a7 supporting rod, a8 fixing rod and a9 bulge.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to 15, a virus testing apparatus for testing a reaction tube a loaded with a sample, the virus testing apparatus comprising a housing 1, a sample holder 2, a testing holder 3, a heating device 4, an excitation light source 5, a testing mechanism 6 and a control unit c; the shell 1 is provided with a detection cavity 10 and an opening 11 for communicating the detection cavity 10 with the outside, the heating device 4 is arranged in the shell 1 and is electrically connected with the control unit c, and the heating device 4 can heat the detection cavity 10; the sample rack 2 is used for loading the reaction tube a, and the sample rack 2 can be arranged in the detection cavity 10; the detection frame 3 is connected with the shell 1 in a sliding way and can cover the opening 11; the excitation light source 5 is arranged in the detection cavity 10 and is electrically connected with the control unit c; the detection mechanism 6 comprises a surrounding part 60 and a detection unit 61, the surrounding part 60 is provided with a detection groove b, the detection unit 61 is arranged in the detection groove b and is electrically connected with the control unit c, the shell 1 is also provided with a lifting groove 12 communicated with the detection cavity 10, and the surrounding part 60 is arranged in the lifting groove 12 in a lifting way; the heating device 4 can heat the detection cavity 10 to heat the reaction tube a in the detection cavity 10; the excitation light source 5 can irradiate the reaction tube a; the surrounding member 60 may be raised and the lower portion of the reaction tube a may be placed in the detection bath b so that the detection unit 61 may detect the reaction tube a.

Specifically, in the embodiment of the present invention, the heating device 4 is embedded in the inner wall of the detection cavity 10, the heating device 4 is preferably an electric heating wire, before the sample is detected, the sample needs to be placed in the detection cavity 10, so that the sample is heated and inactivated, and then the sample is cooled; after cooling, taking out the reaction tube a, adding DNA amplification raw materials and fluorescent materials into the sample in the reaction tube a, putting the reaction tube a into the detection cavity 10 again, operating the heating device 4, raising the temperature in the detection cavity 10 to a temperature suitable for DNA amplification, keeping the temperature constant for a period of time, and greatly increasing the number of virus DNA molecules in the sample so as to facilitate the detection of the detection mechanism 6; after the sample DNA in the reaction tube a is amplified, the excitation light source 5 is started and irradiates the reaction tube a, so that the fluorescent component in the reaction tube a is activated; in this embodiment, as shown in fig. 8 and 9, the lifting groove 12 is further provided with a driving unit d, the surrounding member 60 can be driven by the driving unit d to lift after the excitation light source 5 irradiates the reaction tube a and activates the fluorescent component in the sample, and the lower portion of the reaction tube a is placed in the detection groove b, so that an environment which is darker and is not easily affected by stray light is formed in the detection groove b, and the lower portion of the reaction tube a is surrounded by the detection groove b, so that the detection unit 61 can isolate most of the stray light influence when detecting the reaction tube a, thereby improving the detection accuracy. And because the detection groove b is darker, the detection unit 61 can detect the virus in the sample more easily when the fluorescence intensity is weaker due to less virus molecules, so the invention also has the function of improving the detection sensitivity.

Further, a plurality of reaction tubes a may be mounted on the sample holder 2, a plurality of detection grooves b and a plurality of corresponding detection units 61 may be provided on the enclosure 60, and the plurality of reaction tubes a may be respectively inserted into the plurality of detection grooves b. The embodiment supports a plurality of samples to be detected simultaneously, greatly saves the time consumed for detection, and the bottom of each reaction tube a is respectively arranged in the independent detection groove b, so the fluorescence intensity detection of each reaction tube a is not influenced by the fluorescence intensity of the adjacent reaction tubes a, and each sample can be efficiently and accurately detected respectively.

Further, referring to fig. 10 and 11, the virus detector further includes a receiving rack 7, the receiving rack 7 is used for mounting the sample rack 2, the receiving rack 7 is fixedly mounted on the detecting rack 3, and is disposed in the detecting cavity 10 when the detecting rack 3 covers the opening 11. The detection frame 3 comprises an upper cover plate 30, a plurality of lifting rods 31 and an elastic reset piece 32, one ends of the lifting rods 31 are fixedly connected to the upper cover plate 30, the other ends of the lifting rods 31 can extend into the detection cavity 10 and are in sliding connection with the shell 1, and the bearing frame 7 is fixedly connected to the lifting rods 31; one end of the elastic reset piece 32 is connected with one end of the lifting rod 31 extending into the detection cavity 10, and the other end of the elastic reset piece 32 is connected with the shell 1, so that the lifting rod 31 continuously receives a force moving in a direction away from the detection cavity 10. In this embodiment, the elastic restoring member 32 is preferably a tension spring in order to reduce the stroke length of the lifting rod 31 and the height of the housing 1.

Further, referring to fig. 10 and 11, the detecting frame 3 further includes a rotating member 33 and a pressing plate 34, the rotating member 33 is rotatably connected with the pressing plate 34, the plurality of lifting rods 31 are all arranged by penetrating through the pressing plate 34 and slidably connected with the pressing plate 34, and the pressing plate 34 is arranged above the receiving frame 7; one of the lifting rods 31 is also provided with threads and can be in threaded connection with the rotating part 33, the rotating part 33 is rotated to enable the pressing plate 34 to slide along the lifting rod 31, the pressing plate 34 can be pressed at the top of the reaction tube a placed on the sample rack 2, the phenomenon that the plug cover of the reaction tube a is bounced off due to expansion caused by heat and contraction caused by cold in the air inside the reaction tube a is further prevented, and the sample is effectively prevented from being evaporated or leaked to pollute the instrument in the inactivation process.

Further, referring to fig. 10 and 11, the detecting rack 3 further includes a rotary cover 35, the rotary cover 35 is rotatably connected to the upper cover plate 30, a position-locking protrusion 350 is further disposed on a side of the rotary cover 35, a position-locking groove 13 is further disposed on the housing 1 for connecting the opening 11 and the detecting cavity 10, and the position-locking protrusion 350 can slide in the position-locking groove 13. The locking groove 13 is a U-shaped groove, and has a first end connected to the opening 11 and a second end not connected to the opening 11, as shown in fig. 7.

Specifically, after the sample rack 2 is mounted on the receiving rack 7, the screw cap 35 is pressed downward and the detent projection 350 enters from the first end of the detent groove 13, slides along the "U" shaped detent groove 13 to the second end thereof, and the screw cap 5 is pressed by the elastic restoring member 32, so that the screw cap 35 is tightly pressed against the opening 11 and seals the opening 11.

Furthermore, the fluorescent component is combined with the virus DNA during virus DNA amplification, the fluorescent component is activated only when absorbing light with a specific wavelength and releases fluorescence longer than the wavelength of the absorbed light, and the number of virus DNA molecules in the sample can be measured by detecting the intensity of the released fluorescence. However, when the detecting unit 61 detects the fluorescence intensity, it may cause the problem of inaccurate detection of the fluorescence intensity due to the influence of noise waves of other wavelengths emitted from the excitation light source 5, so in the embodiment of the present invention, referring to fig. 5, 8 and 9, the virus detecting apparatus further includes a first filter 2a, the bottom of the detecting chamber 10 is provided with an annular groove 14, the excitation light sources 5 are annularly distributed in the annular groove 14, the first filter 2a is installed at the notch of the annular groove 14 and covers the excitation light source 5, and since the sample is generally deposited at the bottom of the reaction tube a, the irradiation direction of the excitation light source 5 is obliquely upward, so as to irradiate all samples in the reaction tube a as much as possible. Referring to fig. 12 and 13, the virus detector further includes a second filter 3a, the surrounding member 60 includes an upper member 601 and a lower member 602, the lower member 602 is disposed in the lifting groove 12 in a liftable manner, and the upper member 601 is detachably connected to the top of the lower member 602; the detection groove b comprises a first groove b1 and a second groove b2 which are communicated with each other, the first groove b1 is arranged in the upper piece 601, the second groove b2 is arranged in the lower piece 602, the detection unit 61 is arranged at the groove bottom of the second groove b2, and the second filter lens a3 is arranged at the top of the second groove b 2. Wherein, the first filter lens 2a or the second filter lens 3a can be replaced correspondingly according to different fluorescent materials, and the upper piece 601 and the lower piece 602 are arranged to facilitate the disassembly and replacement of the second filter lens 3 a. Further, the radius of the second filter 3a is larger than the radius of the first groove b1, so that the second filter 3a can be prevented from being separated from the first groove b1 after the upper member 601 is closed to the top of the lower member 602.

After light emitted by the excitation light source 5 passes through the first filter 2a, stray light is filtered, only light with a specific wavelength band is left to irradiate the reaction tube a, and the second filter 3a is used for filtering light waves except for fluorescence emitted by the reaction tube a, so that the illumination intensity detected by the detection unit 61 is approximate to the received fluorescence intensity emitted by the reaction tube a, the influence of the stray light on the detection result is greatly reduced, and the detection precision is improved.

Furthermore, the virus detector further comprises a first air extractor 4a and a second air extractor 5a, the housing 1 is further provided with an air inlet 15 and an air outlet 16, the first air extractor 4a and the second air extractor 5a are both installed in the detection cavity 10 and are respectively communicated with the air inlet 15 and the air outlet 16, and the first air extractor 4a and the second air extractor 5a are both electrically connected with the control unit c. Wherein, first air exhaust 4a is used for detecting the chamber 10 with the outside air suction in, and second air exhaust 5a is used for discharging the air in detecting the chamber 10 to the external world, and the setting of first air exhaust 4a and second air exhaust 5a can carry out the high temperature inactivation back to the sample for detect the cooling rate in chamber 10, thereby reach the purpose that makes reaction tube a cool off fast.

Further, referring to fig. 14 and 15, since the virus detector needs to take the sample rack 2 out of the detection cavity 10 and add the DNA amplification material and the fluorescent material during the use process, in this embodiment, the housing 1 is further provided with a console for temporarily placing the sample rack 2, so as to conveniently add the material to the plurality of reaction tubes a on the sample rack 2. Therefore, the virus detector further comprises a support frame 6a and a plurality of support rods 7a, the sample frame 2 can be arranged on the support frame 6a, the top of the shell 1 is further provided with a containing groove 17, one ends of the support rods 7a are hinged with the support frame 6a, and the other ends of the support rods 7a are hinged in the containing groove 17, so that the support frame 6a can swing and can be contained in the containing groove 17. In this embodiment, the four support rods 7a are preferably connected to four corners of the support frame 6a, and a fixing rod 8a is further fixedly connected between the two support rods 7a at the rear side, and the swinging support rod 7a can further make the fixing rod 8a abut against the top of the accommodating groove 17 for supporting and fixing the position of the support frame 6 a. One end of the support frame 6a is further provided with a protrusion 9a, and when the support frame 6a is accommodated in the accommodating groove 17, the protrusion 9a protrudes out of the accommodating groove 17, so that a user can conveniently pull the support frame 6a through the protrusion 9a, and the support frame 6a can be supported.

It should be noted that the control of the heating device 4, the excitation light source 5, the driving unit c, the detecting unit 61, the first pumping device a4 and the second pumping device a5 by the control unit c is prior art and will not be described in detail in the present invention.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.

The relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present application unless specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective portions shown in the drawings are not drawn in an actual proportional relationship for the convenience of description. Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.

In the description of the present application, it is to be understood that the orientation or positional relationship indicated by the directional terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal" and "top, bottom", etc., are generally based on the orientation or positional relationship shown in the drawings, and are used for convenience of description and simplicity of description only, and in the case of not making a reverse description, these directional terms do not indicate and imply that the device or element being referred to must have a particular orientation or be constructed and operated in a particular orientation, and therefore, should not be considered as limiting the scope of the present application; the terms "inner and outer" refer to the inner and outer relative to the profile of the respective component itself.

Spatially relative terms, such as "above … …," "above … …," "above … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary term "above … …" can include both an orientation of "above … …" and "below … …". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

It should be noted that the terms "first", "second", and the like are used to define the components, and are only used for convenience of distinguishing the corresponding components, and the terms have no special meanings unless otherwise stated, and therefore, the scope of protection of the present application is not to be construed as being limited.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A virus detector can detect a reaction tube (a) loaded with a sample, and is characterized by comprising a shell (1), a sample rack (2), a detection rack (3), a heating device (4), an excitation light source (5), a detection mechanism (6) and a control unit (c);

the detection device is characterized in that the shell (1) is provided with a detection cavity (10) and an opening (11) for communicating the detection cavity (10) with the outside, the heating device (4) is arranged in the shell (1) and is electrically connected with the control unit (c), and the heating device (4) can heat the detection cavity (10);

the sample rack (2) is used for loading a reaction tube (a), and the sample rack (2) can be placed in a detection cavity (10);

the detection frame (3) is connected with the shell (1) in a sliding way and can cover the opening (11);

the excitation light source (5) is arranged in the detection cavity (10) and is electrically connected with the control unit (c);

the detection mechanism (6) comprises a surrounding part (60) and a detection unit (61), a detection groove (b) is formed in the surrounding part (60), the detection unit (61) is arranged in the detection groove (b) and is electrically connected with a control unit (c), a lifting groove (12) communicated with the detection cavity (10) is further formed in the shell (1), and the surrounding part (60) is arranged in the lifting groove (12) in a lifting mode;

the heating device (4) can heat the detection cavity (10) so as to heat the reaction tube (a) in the detection cavity (10); the excitation light source (5) can irradiate the reaction tube (a); the surrounding member (60) may be raised and the lower portion of the reaction tube (a) may be placed in the detection groove (b) so that the detection unit (61) may detect the reaction tube (a).

2. The virus detecting apparatus according to claim 1, wherein a plurality of reaction tubes (a) are loaded on the sample holder (2), a plurality of detection grooves (b) and a plurality of corresponding detection units (61) are provided on the surrounding member (60), and the plurality of reaction tubes (a) are respectively inserted into the plurality of detection grooves (b).

3. The virus detector according to claim 1, further comprising a receiving rack (7), wherein the receiving rack (7) is used for mounting the sample rack (2), and the receiving rack (7) is fixedly mounted on the detection rack (3) and is disposed in the detection chamber (10) when the detection rack (3) covers the opening (11).

4. The virus detector according to claim 3, wherein the detection frame (3) comprises an upper cover plate (30) and a plurality of lifting rods (31), one end of each of the plurality of lifting rods (31) is fixedly connected to the upper cover plate (30), the other end of each of the plurality of lifting rods (31) is capable of extending into the detection cavity (10) and slidably connected to the housing (1), and the receiving frame (7) is fixedly connected to the lifting rods (31).

5. The virus detector according to claim 4, wherein the detection frame (3) further comprises a rotating member (33) and a pressing plate (34), the rotating member (33) is rotatably connected with the pressing plate (34), the plurality of lifting rods (31) are arranged through the pressing plate (34) and slidably connected with the pressing plate (34), and the pressing plate (34) is arranged above the bearing frame (7); one of the lifting rods (31) is also provided with threads and can be in threaded connection with a rotating piece (33), and the pressure plate (34) can slide along the lifting rod (31) by rotating the rotating piece (33).

6. The virus detector according to claim 4, wherein the detection frame (3) further comprises a rotary cover (35), the rotary cover (35) is rotatably connected with the upper cover plate (30), a clamping boss (350) is further arranged on a side edge of the rotary cover (35), a clamping groove (13) for connecting the opening (11) and the detection cavity (10) is further arranged on the housing (1), and the clamping boss (350) can slide in the clamping groove (13).

7. The virus detector according to claim 1, further comprising a first filter (2a), wherein the bottom of the detection chamber (10) is provided with an annular groove (14), the excitation light sources (5) are annularly distributed in the annular groove (14), the first filter (2a) is installed at the notch of the annular groove (14) and covers the excitation light sources (5), and the irradiation direction of the excitation light sources (5) is obliquely arranged upward.

8. The virus detector according to claim 1, further comprising a second filter (3a), wherein the enclosure (60) comprises an upper piece (601) and a lower piece (602), the lower piece (602) is arranged in the lifting groove (12) in a lifting manner, and the upper piece (601) is detachably connected to the top of the lower piece (602); the detection groove (b) comprises a first groove (b1) and a second groove (b2) which are communicated with each other, the first groove (b1) is arranged in the upper piece (601), the second groove (b2) is arranged in the lower piece (602), the detection unit (61) is arranged at the bottom of the second groove (b2), and the second filter lens (a3) is arranged at the top of the second groove (b 2).

9. The virus detector according to claim 1, further comprising a first air extractor (4a) and a second air extractor (5a), wherein the housing (1) is further provided with an air inlet (15) and an air outlet (16), the first air extractor (4a) and the second air extractor (5a) are both installed in the detection chamber (10) and are respectively communicated with the air inlet (15) and the air outlet (16), and the first air extractor (4a) and the second air extractor (5a) are both electrically connected with the control unit (c).

10. The virus detector according to claim 1, further comprising a support frame (6a) and a plurality of support rods (7a), wherein the sample holder (2) is mountable on the support frame (6a), the top of the housing (1) is further provided with a receiving groove (17), one end of each of the plurality of support rods (7a) is hinged to the support frame (6a), and the other end of each of the plurality of support rods is hinged to the receiving groove (17), so that the support frame (6a) can swing and be received in the receiving groove (17).