CN111920920A - Traditional Chinese medicine formula for preventing and treating viral pneumonia and patent medicine preparation method - Google Patents
Traditional Chinese medicine formula for preventing and treating viral pneumonia and patent medicine preparation method Download PDFInfo
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Abstract
A traditional Chinese medicine formula for preventing and treating viral pneumonia and a patent medicine preparation method are provided, wherein the traditional Chinese medicine formula comprises, by weight, 15-25 parts of lily, 10-20 parts of loquat leaf, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of straight ladybell root, 15-30 parts of dwarf lilyturf tuber, 15-30 parts of radix stemonae, 15-30 parts of roasted malt, 15-30 parts of chicken's gizzard-membrane, 10-15 parts of Chinese magnoliavine fruit, 15-30 parts of dried rehmannia root, 10-20 parts of mulberry leaf, 10-15 parts of. Through the selection and matching of raw materials in the formula and the improvement of a preparation process, the virus-resistant efficacy of the Chinese patent medicine is improved, and the aims of dredging the five internal organs and channels, strengthening the body resistance and eliminating pathogenic factors to protect the five internal organs and the lung are achieved.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine prevention and treatment of viral pneumonia, and particularly relates to a traditional Chinese medicine formula for preventing and treating viral pneumonia and a method for preparing patent medicines.
Background
The development course of traditional Chinese medicine for thousands of years highlights the prevalence and control of infectious diseases. Not only have the representative academic achievements such as the Nei Jing, the difficult Jing, the Shang Han Lun, the pestilence, the Wen Bing Bian and the like, but also have the immune thought, the technical prevention and control, the clinical treatment and the Chinese patent medicine ceremony such as the acne vaccine and the like to donate to the human beings. Plays an important role in treating measles, pneumonia, influenza, epidemic hemorrhagic fever, SARS and new coronary pneumonia in 2020. At present, the new coronary pneumonia has a global outbreak and a normalized trend, which causes disastrous losses to the lives and socio-economy of people. Even after the nucleic acid of a patient turns negative, a plurality of sequelae still exist, and serious warning is further provided after the disease is infected repeatedly. Before raining, the silk and muzzle make further disease-free prevention, prevent diseases and prevent deformation, strengthen the body resistance and eliminate pathogenic factors, consolidate the foundation and trace the source, and are really urgent.
The achievement of resisting epidemic by combining Chinese and western medicine in China shows that the technology of virus discrimination and detection and qualification in western medicine is really a key technical means. The comprehensive control decision for spreading the infection source formed by the superiority of the national social system is a decisive factor. In the critical battle of viral eradication and life saving, controlling the increment of critical patients and reducing the mortality of critical patients becomes the hope of anti-epidemic success. Modern medical equipment and a series of clinical treatment specifications in the rescue carried out by the clinical experience of western medicine, including vital sign maintenance of critical patients, are powerful to support, but the cost of the effort is also enormous. Carefully analyzing the whole epidemic prevention process. The epidemic prevention can be fully won, and special attention should be paid to the stage of mutual support of resisting epidemic situation spread, and the theory of origin-fixing, tracing and dialectical treatment of traditional Chinese medicine and traditional Chinese medicine is a powerful support for blocking new coronavirus and reducing mortality.
The traditional Chinese medicine has good performance in battles of fighting against the new coronary pneumonia, and changes the early stage of epidemic prevention from being matched into a main role. News report data show that cure rate is as high as 90%. In the process, three medicines such as a lotus antipyretic capsule and the like and three parts such as a lung-clearing toxin-expelling decoction and the like have obvious curative effects, greatly reduce the activity of new coronavirus entering a human body, stimulate the immune function of the human body, and powerfully prevent the disease condition of patients from expanding and enable the world to be scraped.
From the analysis of the technical level, the western medicine can not effectively monitor the focus of other organs in the first-aid stage of treating the new coronary pneumonia except for the specific medicine and the vaccine, thereby causing factor storm and complications. The death rate of the elderly is high because the patients cannot effectively restrain organic changes of the respiratory system and have negative effects on other systems or organs, so that the death rate is high. The traditional Chinese medicine focuses on the etiology and pathogenesis, eliminates the living environment of pathogens by taking the symptoms and the root causes into consideration and regulating, and mobilizes the self-healing function of the human body to generate immune antibodies, namely the theory relationship of 'lung protection by joint administration of five zang organs' and 'body strengthening' is fundamental and mutually restricted, so that the traditional Chinese medicine conforms to the 'lifting and exiting' of the human body, generates the treatment effects of 'lung protection by five zang organs, internal storage of vital qi and no dryness of pathogens', and can achieve the effects of body building and body building while inhibiting the development of viruses. The concept of Chinese medicine is continuously summarized and developed, and the improvement of clinical effects, application specifications and selection of application range of the Chinese patent medicine becomes an urgent task for Chinese medicine workers.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine formula for preventing and treating viral pneumonia and a patent medicine preparation method, and the traditional Chinese medicine formula can improve the virus-resistant effect of the Chinese patent medicine by selecting and matching raw materials in the formula and improving the preparation process, and can achieve the purposes of dredging five internal organs and channels, strengthening body resistance and eliminating pathogenic factors to protect the five internal organs and lungs.
The technical scheme adopted by the invention is as follows: a traditional Chinese medicine formula for preventing and treating viral pneumonia comprises, by weight, 15-25 parts of lily, 10-20 parts of loquat leaves, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 15-30 parts of radix stemonae, 15-30 parts of roasted malt, 15-30 parts of endothelium corneum gigeriae galli, 10-15 parts of schisandra chinensis, 15-30 parts of radix rehmanniae recen, 10-20 parts of mulberry leaves, 10-15 parts of dark plum fruits and 10-15 parts of medicinal cyathula roots.
A preparation method of a patent medicine of a traditional Chinese medicine formula for preventing and treating viral pneumonia comprises the following steps:
step one, preparing a concentrated solution of a basic drug:
weighing 15-25 parts of lily, 15-30 parts of radix rehmanniae recen, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of radix stemonae, 15-30 parts of fried malt, 10-15 parts of schisandra chinensis, 10-20 parts of mulberry leaf, 10-20 parts of loquat leaf, 10-15 parts of dark plum and 10-15 parts of medicinal cyathula root according to parts by weight, and putting into a container;
injecting natural soda water into the container, and soaking the medicinal materials for 30-60min, wherein the liquid level of the natural soda water is 3-5cm higher than the liquid level of the medicinal materials;
thirdly, heating the container at the temperature of 120-;
fourthly, adding water into the container, wherein the liquid level of the water is 3-5cm higher than the medicine surface, and repeating the third step;
fifthly, filtering and concentrating the medicine juice obtained in the third step and the fourth step to obtain concentrated solution;
step two, preparing the dry powder of the endothelium corneum gigeriae galli:
1) weighing 15-30 parts of endothelium corneum gigeriae galli according to parts by weight, and then cleaning and drying the endothelium corneum gigeriae galli;
2) putting the sand into a casserole, frying the sand to a flexible state by flame of 150-220 ℃, putting the endothelium corneum gigeriae galli in the casserole, stir-frying, scalding the endothelium corneum gigeriae galli until the endothelium corneum gigeriae is foamed and curled and the color is light yellow, taking out the mixture in the casserole, screening to obtain the processed endothelium corneum gigeriae galli, cooling, grinding into powder, and screening by a screen to prepare the dry powder of the endothelium corneum gigeriae galli;
step three, preparing a patent medicine for preventing and treating viral pneumonia:
1) drying the concentrated solution obtained in the step one, and screening by using a screen to obtain refined dry powder; mixing with the endothelium corneum Gigeriae Galli dry powder, stirring, and making into granule or capsule;
2) and (3) mixing the concentrated solution obtained in the first step, the dried chicken's gizzard-membrane powder obtained in the second step, natural soda water, a sweetening agent, a stabilizer and a preservative, and uniformly stirring to prepare an oral mixture.
Further, the mesh size of the screen in the second step and the third step is between 120 and 200 meshes.
Further, the mixing weight fraction ratio of the concentrated solution, the chicken's gizzard-membrane dry powder, the natural soda water, the sweetening agent, the stabilizing agent and the preservative in the step three 2) is 28:1:70:0.8:0.1: 0.1.
The basic theory of the traditional Chinese medicine formula for preventing and treating viral pneumonia is as follows: the traditional Chinese medicine has unique academic principles and corresponding diagnosis and treatment methods for treating viral diseases, and is continuously inherited and innovated for hundreds of years; the five internal organs are the four-season lung protection, which is derived from the academic principle of strengthening the body resistance and eliminating pathogenic factors in the traditional Chinese medicine and the effective experience of a plurality of years, the internal classic of the internal classic has the pathogenesis of 'healthy qi and pathogenic factors attacking each other', the condition that the deficiency of the healthy qi is the internal basis of the disease and the exogenous pathogenic factors are the necessary condition for the cough, and the dominant effect of the healthy qi in the cough prevention is emphasized. The "plain questions & acanthosis treatise" is in the name: if the disease is not infected, the healthy qi exists in the body and the pathogenic factors cannot be dried. "Su Wen & Yi Pi Bing Lun of diseases" is characterized by: when the pathogenic factors are mixed, qi is always deficient. "Zhang Zhongjing" is pointed out in "jin Kui Yao L ü e zang-fu Jing Luo Zhen Yi (syndrome of zang-fu meridians followed by pulses of disease): if the five zang organs are unobstructed, the body is calm, and if the body is weak, the skin is not obstructed. The key to the development of the disease is the disturbance of qi of the zang-fu organs and weakness. The lung is the "delicate organ" which is the canopy of the zang-fu organs, the lung is the skin and hair, and the skin and hair are the barrier of the defense. When lung qi is deficient, the wei-defensive qi is insecure, and it is easy to invade by exogenous pathogens, causing the lung to lose its function of dispersing and descending, and the lung qi to go up and down, resulting in cough. The lung yin is consumed for a long time, the lung is not nourished, the lung yin deficiency is caused, the lung dryness is caused by the yin deficiency, the qi movement is disordered, exogenous pathogenic qi firstly enters the lung because the wind is the growth of hundreds of diseases, and the cough is treated by the lung and the kidney according to the condition that the spleen is a phlegm generating device and the lung is a phlegm storing device, so that the lung and the spleen are treated simultaneously, the kidney mainly receives qi and the lung mainly breathes, so the five-viscera lung protecting and treating method is to support the healthy energy, strengthen the healthy energy and eliminate the pathogenic factors, protect the lung by five viscera, preferably tonify the lung qi, nourish the lung yin, dry dampness and reduce phlegm, support earth and promote the growth of gold, and nourish the lung and the kidney simultaneously.
The prescription idea of the invention is different from three parts of Chinese patent medicine, namely 'three medicines' such as 'Lianhua Qingwen capsule' and 'Qingfei Jiedu Tang' applied to resisting new coronary pneumonia in 2020, emphasizes the action on heart, liver, spleen, kidney and lung to strengthen the healthy qi of five internal organs and achieve the central purpose of countervailing and protecting lung.
The traditional Chinese medicine formula based on 'five internal organs protect lung and treat' is unique in medicine, most of the selected medicines do not appear in the published prescription of the Chinese patent medicine and the traditional Chinese medicine decoction for resisting the new coronary pneumonia, and the prescription is formed by combining eight main medicines, six auxiliary medicines and fourteen auxiliary medicines; if necessary, the composition can be added with medicines or combined with formula granules and Chinese patent medicines. Is particularly suitable for controlling and restoring yang in the prevention, cure and prognosis rehabilitation period of new coronary pneumonia, and is a powerful supplement for three medicines such as lotus antipyretic capsules and the like and three parties such as lung-clearing and toxin-expelling soup and the like.
The traditional Chinese medicine formula of the invention comprises the following medicinal compositions: monarch drug: lily and loquat leaves are mainly used for tonifying lung and dissipating heat; ministerial drugs: rhizoma Atractylodis Macrocephalae and rhizoma Dioscoreae, with the effects of invigorating spleen and stomach, and earthing up and promoting the growth of gold as auxiliary materials; adjuvant drugs: radix adenophorae, radix ophiopogonis, schisandra chinensis and radix cyathulae have the effects of tonifying kidney water, nourishing liver blood and preventing wood fire from being spread; a messenger drug: mulberry leaf, stemona root and dark plum fruit, enhance the functions of freeing lung and relieving cough, and assist monarch drugs to play good effects; endothelium corneum Gigeriae Galli, fructus Hordei Germinatus preparata, and radix rehmanniae have effects of strengthening middle energizer and lowering the lower energizer to maintain the congenital and acquired constitution of life.
The beneficial effects produced by adopting the invention are as follows: the invention is especially suitable for preventing new crown pneumonia, and has 98% of curbing and yang-recovering prevention effect and 92% of cure rate for mild symptoms in the prognosis and recovery period.
Detailed Description
A traditional Chinese medicine formula for preventing and treating viral pneumonia comprises, by weight, 15-25 parts of lily, 10-20 parts of loquat leaves, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 15-30 parts of radix stemonae, 15-30 parts of roasted malt, 15-30 parts of endothelium corneum gigeriae galli, 10-15 parts of schisandra chinensis, 15-30 parts of radix rehmanniae recen, 10-20 parts of mulberry leaves, 10-15 parts of dark plum fruits and 10-15 parts of medicinal cyathula roots.
The traditional Chinese medicine formula of the invention comprises the following medicinal compositions: lily, radix rehmanniae, radix adenophorae, radix ophiopogonis, dark plum, schisandra chinensis, mulberry leaf, loquat leaf, radix stemonae, radix cyathulae, endothelium corneum gigeriae galli, roasted malt, bighead atractylodes rhizome and Chinese yam. The method is divided according to monarch, minister, assistant and guide, and comprises the following steps:
monarch drug: lily and loquat leaves are used for tonifying lung and dissipating heat;
ministerial drugs: bighead atractylodes rhizome and Chinese yam are used for strengthening the spleen and stomach;
adjuvant drugs: radix adenophorae, radix ophiopogonis, schisandra chinensis and radix cyathulae, and has the effects of tonifying kidney water and nourishing liver blood;
a messenger drug: mulberry leaf, stemona root, chicken's gizzard-membrane, malt, dried rehmannia root and dark plum.
The pharmacology of the medicine is as follows: lily is used for clearing heat, nourishing yin, moistening dryness, nourishing heart and spleen, and harmonizing five internal organs and all pulses; raw rehmannia root has the effects of nourishing yin and promoting the production of body fluid, regulating the liver and spleen and benefiting yin and blood; the radix adenophorae and the radix ophiopogonis have the effects of clearing away the lung-heat, nourishing yin, moistening dryness and promoting the production of body fluid, the four medicines are used together to nourish yin and promote the production of body fluid, and the dark plum has the effects of astringing lung yin and arresting sweating; the schisandra chinensis is sour in nature and sweet and warm in taste, enters spleen, heart and spleen channels, has the effects of astringing, arresting discharge, tonifying qi, promoting the production of body fluid, protecting lung fluid and nourishing kidney water, and can astringe lung, relieve cough and nourish lung when used together; the mulberry leaves are sweet and bitter in nature, enter lung and liver meridians, and have the effects of dispelling wind and clearing heat; folium Eriobotryae is added to clear away heat, resolve phlegm and relieve cough; the radix stemonae warms and moistens lung qi and relieves cough, and the three are used together to dispel wind and clear heat, which is fit for 'wind being the long of all diseases'; radix cyathulae is neutral in nature and sweet in taste, and has the effects of tonifying liver, tonifying kidney and invigorating spleen; endothelium corneum Gigeriae Galli is sweet and sour in flavor, neutral in nature, and can enter spleen and kidney to eliminate food stagnation; matching with the roasted malt to strengthen the spleen and stomach; the largehead atractylodes rhizome enters spleen and stomach channels and has the functions of tonifying qi, strengthening spleen and eliminating dampness; yam excels in entering lung and stomach, is assisted by the herbs for regulating and nourishing the civil engineering and herbs for excess and consumptive diseases, in the theory of five elements in the middle-earth, Yam can astringe the liver to dredge too much by mediating the qi of the middle-earth, astringe the lung to descend too much, and move the whole body.
The application range of the traditional Chinese medicine formula of the invention is as follows: has obvious effect on patients with early stage and mild symptoms, and needs to be matched with other medicines for treating critical illness.
A preparation method of a patent medicine of a traditional Chinese medicine formula for preventing and treating viral pneumonia comprises the following steps:
step one, preparing a concentrated solution of a basic drug:
weighing 15-25 parts of lily, 15-30 parts of radix rehmanniae recen, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of radix stemonae, 15-30 parts of fried malt, 10-15 parts of schisandra chinensis, 10-20 parts of mulberry leaf, 10-20 parts of loquat leaf, 10-15 parts of dark plum and 10-15 parts of medicinal cyathula root according to parts by weight, and putting into a container;
injecting natural soda water into the container, and soaking the medicinal materials for 30-60min, wherein the liquid level of the natural soda water is 3-5cm higher than the liquid level of the medicinal materials;
thirdly, heating the container at the temperature of 120-;
fourthly, adding water into the container, wherein the liquid level of the water is 3-5cm higher than the medicine surface, and repeating the third step;
fifthly, filtering and concentrating the medicine juice obtained in the third step and the fourth step to obtain concentrated solution;
step two, preparing the dry powder of the endothelium corneum gigeriae galli:
1) weighing 15-30 parts of endothelium corneum gigeriae galli according to parts by weight, and then cleaning and drying the endothelium corneum gigeriae galli;
2) putting the sand into a casserole, frying the sand to a flexible state by flame of 150-220 ℃, putting the endothelium corneum gigeriae galli in the casserole, stir-frying, scalding the endothelium corneum gigeriae galli until the endothelium corneum gigeriae is foamed and curled and the color is light yellow, taking out the mixture in the casserole, screening to obtain the processed endothelium corneum gigeriae galli, cooling, grinding into powder, and screening by a screen to prepare the dry powder of the endothelium corneum gigeriae galli;
step three, preparing a patent medicine for preventing and treating viral pneumonia:
1) drying the concentrated solution obtained in the step one, and screening by using a screen to obtain refined dry powder; mixing with the endothelium corneum Gigeriae Galli dry powder, stirring, and making into granule or capsule;
2) and (3) mixing the concentrated solution obtained in the first step, the dried chicken's gizzard-membrane powder obtained in the second step, natural soda water, a sweetening agent, a stabilizer and a preservative, and uniformly stirring to prepare an oral mixture.
The mesh size of the screen in the second step and the third step is between 120-200 meshes.
The mixing weight fraction ratio of the concentrated solution, the dry powder of the endothelium corneum gigeriae galli, the natural soda water, the sweetening agent, the stabilizing agent and the preservative in the step three 2) is 28:1:70:0.8:0.1: 0.1.
To demonstrate the therapeutic efficacy of the present invention in the prevention and treatment of viral pneumonia, particularly neocoronary pneumonia in 2020, it was further confirmed by the following case observations that the patient sources were all from european office.
The control group takes 100 cases of conventional treatment products, wherein the dosage of the medicines is matched with that of the experimental group, the medicines are taken for 5-7 days, the curative effect judgment standard is determined, and the relevant curative effect evaluation standard is determined according to MHO and the clinical guidance principle of new traditional Chinese medicines formulated by the health department of China.
After a single course of treatment, clinical results were assessed: the results of evaluation of the influence on the blood indices are shown in Table 1.
TABLE 1
Total efficiency of the bad cases of the effective cases of the group significant cases
Experimental group 10035605095%
Control group 10096823077%
As can be seen from the table 1, the total effective rate reaches 95 percent after the traditional Chinese patent medicine is taken by 114 various patients for 5 to 7 days of a treatment course; and the effective rate of 98 percent in the prevention effect test of medical care personnel is achieved.
The experiments prove that the traditional Chinese medicine formula can effectively prevent and treat viral pneumonia and has a very obvious effect.
Claims (4)
1. A traditional Chinese medicine formula for preventing and treating viral pneumonia is characterized in that: the traditional Chinese medicine formula comprises, by weight, 15-25 parts of lily, 10-20 parts of loquat leaf, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 15-30 parts of radix stemonae, 15-30 parts of roasted malt, 15-30 parts of endothelium corneum gigeriae galli, 10-15 parts of schisandra chinensis, 15-30 parts of radix rehmanniae recen, 10-20 parts of mulberry leaf, 10-15 parts of dark plum and 10-15 parts of radix cyathulae.
2. The patent medicine preparation method of the traditional Chinese medicine formula for preventing and treating viral pneumonia, which is based on claim 1, is characterized by comprising the following steps:
step one, preparing a concentrated solution of a basic drug:
weighing 15-25 parts of lily, 15-30 parts of radix rehmanniae recen, 15-30 parts of adenophora stricta, 15-30 parts of radix ophiopogonis, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Chinese yam, 15-30 parts of radix stemonae, 15-30 parts of fried malt, 10-15 parts of schisandra chinensis, 10-20 parts of mulberry leaf, 10-20 parts of loquat leaf, 10-15 parts of dark plum and 10-15 parts of medicinal cyathula root according to parts by weight, and putting into a container;
injecting natural soda water into the container, and soaking the medicinal materials for 30-60min, wherein the liquid level of the natural soda water is 3-5cm higher than the liquid level of the medicinal materials;
thirdly, heating the container at the temperature of 120-;
fourthly, adding water into the container, wherein the liquid level of the water is 3-5cm higher than the medicine surface, and repeating the third step;
fifthly, filtering the medicine juice obtained in the third step and the fourth step, and concentrating to obtain concentrated solution;
step two, preparing the dry powder of the endothelium corneum gigeriae galli:
1) weighing 15-30 parts of endothelium corneum gigeriae galli according to parts by weight, and cleaning and drying the endothelium corneum gigeriae galli;
2) putting the sand into a casserole, frying the sand to a flexible state by flame of 150-220 ℃, putting the endothelium corneum gigeriae galli in the casserole, stir-frying, scalding the endothelium corneum gigeriae galli until the endothelium corneum gigeriae is foamed and curled and the color is light yellow, taking out the mixture in the casserole, screening to obtain the processed endothelium corneum gigeriae galli, cooling, grinding into powder, and screening by a screen to prepare the dry powder of the endothelium corneum gigeriae galli;
step three, preparing a patent medicine for preventing and treating viral pneumonia:
1) drying the concentrated solution obtained in the step one, and screening by using a screen to obtain refined dry powder; mixing with the endothelium corneum Gigeriae Galli dry powder, stirring, and making into granule or capsule;
2) and (3) mixing the concentrated solution obtained in the first step, the dried chicken's gizzard-membrane powder obtained in the second step, natural soda water, a sweetening agent, a stabilizer and a preservative, and uniformly stirring to prepare an oral mixture.
3. The method for preparing the patent medicine of the traditional Chinese medicine formula for preventing and treating viral pneumonia according to claim 2, is characterized in that: the mesh size of the screen in the second step and the third step is between 120-200 meshes.
4. The method for preparing the patent medicine of the traditional Chinese medicine formula for preventing and treating viral pneumonia according to claim 2, is characterized in that: the mixing weight fraction ratio of the concentrated solution, the dry powder of the endothelium corneum gigeriae galli, the natural soda water, the sweetening agent, the stabilizing agent and the preservative in the step three 2) is 28:1:70:0.8:0.1: 0.1.
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