CN106620074A - Traditional Chinese medicine for treating periodontitis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating periodontitis and preparation method thereof Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 42
- 201000001245 periodontitis Diseases 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 10
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229940079593 drug Drugs 0.000 claims abstract description 8
- 240000005001 Paeonia suffruticosa Species 0.000 claims abstract description 7
- 235000003889 Paeonia suffruticosa Nutrition 0.000 claims abstract description 7
- 241000405414 Rehmannia Species 0.000 claims abstract description 7
- 244000197580 Poria cocos Species 0.000 claims abstract description 6
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 6
- 244000241872 Lycium chinense Species 0.000 claims description 8
- 244000247747 Coptis groenlandica Species 0.000 claims description 6
- 235000002991 Coptis groenlandica Nutrition 0.000 claims description 6
- 241000522254 Cassia Species 0.000 claims description 5
- 239000012467 final product Substances 0.000 claims description 5
- 235000014347 soups Nutrition 0.000 claims description 5
- 239000002699 waste material Substances 0.000 claims description 5
- 239000000796 flavoring agent Substances 0.000 claims description 2
- 235000019634 flavors Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- 210000003734 kidney Anatomy 0.000 abstract description 7
- 241000173529 Aconitum napellus Species 0.000 abstract description 6
- 210000004185 liver Anatomy 0.000 abstract description 6
- 208000024891 symptom Diseases 0.000 abstract description 5
- 210000002784 stomach Anatomy 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 241000213006 Angelica dahurica Species 0.000 abstract description 2
- 244000241838 Lycium barbarum Species 0.000 abstract description 2
- 235000015459 Lycium barbarum Nutrition 0.000 abstract description 2
- 241000049624 Alisma plantago-aquatica subsp. orientale Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000411851 herbal medicine Species 0.000 abstract 1
- 238000010926 purge Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000002757 inflammatory effect Effects 0.000 description 4
- 208000009596 Tooth Mobility Diseases 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 229940023019 aconite Drugs 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 1
- 235000002710 Ilex cornuta Nutrition 0.000 description 1
- 235000019082 Osmanthus Nutrition 0.000 description 1
- 241000333181 Osmanthus Species 0.000 description 1
- 241000588278 Osmanthus heterophyllus Species 0.000 description 1
- 235000010326 Osmanthus heterophyllus Nutrition 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241001251949 Xanthium sibiricum Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 210000004261 periodontium Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a traditional Chinese medicine for treating periodontitis. The traditional Chinese medicine is prepared from the following herbal medicines in a prescription in parts by weight: 8 to 10 parts of prepared rehmannia root, 8 to 10 parts of common macrocarpium fruit, 8 to 10 parts of barbary wolfberry fruit, 4 to 6 parts of tree peony bark, 4 to 6 parts of poria cocos, 4 to 6 parts of oriental waterplantain rhizome, 1 to 3 parts of prepared common monkshood daughter root, 1 to 3 parts of cassia bark, 1 to 3 parts of Chinese angelica, 1 to 3 parts of rhizoma coptidis and 1 to 3 parts of dried radix rehmanniae. The traditional Chinese medicine for treating the periodontitis has the advantages: components are reasonable, the prescription and symptoms are matched with each other, all medicines cooperate to clear stomach and purge intense heat, nourish yin and clear away heat, and warm the liver and kidney, the traditional Chinese medicine has excellent curative effects on the periodontitis, and the toxic and side effects are small. The invention further discloses a preparation method of the traditional Chinese medicine for treating the periodontitis. The preparation method comprises: decocting all medicines in water; therefore, the step is simple, operability is strong, and the costs are low.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly, to a kind of Chinese medicine of periodontitis and preparation method thereof is treated.
Background technology
Periodontitis refers to a kind of chronic destructive disease occurred in tooth supporting tissue (gum, parodontium etc.), and it is special
Point is gingivitis or oral pocket, tooth mobility and absorption of alveolar bone, and predilection site is more common in adult to grind one's teeth in sleep, and rural area is sent out
Sick rate is higher.Western medical treatment suited the medicine to the illness with local, based on pain relieving, although instant effect, but cure the symptoms, not the disease, easily recur.
The content of the invention
The invention aims to provide a kind of reasonable recipe, square disease is in step with, and toxic and side effect is little, and clinical efficacy is good, tool
There are eliminating stomach-fire, replenishing the vital essence and removing heat, the Chinese medicine of the treatment periodontitis of the work(of warm filling liver kidney.
Present invention also offers a kind of Chinese medicinal preparation method for treating periodontitis, step is simple, workable, cost
It is low.
To achieve these goals, the present invention is employed the following technical solutions：
A kind of Chinese medicine for treating periodontitis, the Chinese medicine is made up of the flavour of a drug of following weight portion：8～10 parts of cultivated lands, 8～10
Part Fructus Corni, 8～10 portions of fruits of Chinese wolfberry, 4～6 parts of root barks of tree peony, 4～6 parts of Poria cocos, 4～6 portions of rhizoma alismatis, 1～3 part of cooked aconite, 1～3 portion of meat
Osmanthus, 1～3 part of Radix Angelicae Sinensis, 1～3 portion of coptis, 1～3 part of dried rhizome of rehmannia.In the Chinese medicine of the treatment periodontitis of the present invention, cultivated land, Fructus Corni, Chinese holly
Matrimony vine, when being classified as monarch drug in a prescription, cultivated land is enriched blood yin-nourishing, and life essence-filling, marrow-benefitting, Fructus Corni has nourishing, stomach invigorating, diuresis, filling liver kidney, replenishing qi and blood
The effects such as, the fruit of Chinese wolfberry is nourishing liver and kidney, benefiting shrewd head, Chinese angelica blood supplementing beneficial gas, the mutual compatibility of cultivated land, Fructus Corni, the fruit of Chinese wolfberry, Radix Angelicae Sinensis,
Up to the effect of kidney tonifying permanent tooth；Cooked aconite, Chinese cassia tree match and help cultivated land, Fructus Corni, the fruit of Chinese wolfberry, Radix Angelicae Sinensis help yang-energy, are ministerial drug；Fu
Siberian cocklebur, rhizoma alismatis, coptis compatibility tonifying lung spleen, clearing heat-fire is adjutant；The root bark of tree peony, dried rhizome of rehmannia clearing heat and cooling blood are to make medicine；All medicines share, plays altogether
Eliminating stomach-fire, replenishing the vital essence and removing heat, the effect of warm filling liver kidney has good curative effect to periodontitis.
A kind of Chinese medicinal preparation method for treating periodontitis, concretely comprises the following steps：Each taste Chinese medicine is weighed by above-mentioned weight
Afterwards, add water and decocted, waste takes soup, obtain final product the Chinese medicine for the treatment of periodontitis.
Preferably, amount of water is 5～10 times of Chinese medicine gross weight.
Therefore, the present invention has the advantages that：
(1) there is provided a kind of Chinese medicine for treating periodontitis, reasonable recipe, square disease is in step with, all medicines share, clearing stomach is played altogether and is rushed down
Fire, replenishing the vital essence and removing heat, the effect of warm filling liver kidney has good curative effect to periodontitis, and toxic and side effect is little；
(2) there is provided a kind of Chinese medicinal preparation method for treating periodontitis, add water to cook, step is simple, operability
By force, low cost.
Specific embodiment
Below by specific embodiment, the present invention will be further described.
Embodiment 1
By 10g cultivated lands, 10g Fructus Cornis, the 10g fruits of Chinese wolfberry, the 6g root barks of tree peony, 6g Poria cocos, 6g rhizoma alismatis, 3g cooked aconites, 3g Chinese cassia trees, 3g
Radix Angelicae Sinensis, the 3g coptiss, the weight proportion of the 3g dried rhizome of rehmannia is weighed after each taste Chinese medicine, plus the water of 10 times of Chinese medicine gross weight is decocted, waste
Soup is taken, the Chinese medicine for the treatment of periodontitis is obtained final product.
Embodiment 2
By 9g cultivated lands, 9g Fructus Cornis, the 9g fruits of Chinese wolfberry, the 5g root barks of tree peony, 5g Poria cocos, 5g rhizoma alismatis, 2g cooked aconites, 2g Chinese cassia trees, 2g works as
Return, the 2g coptiss, the weight proportion of the 2g dried rhizome of rehmannia is weighed after each taste Chinese medicine, plus the water of 8 times of Chinese medicine gross weight is decocted, waste takes
Soup, obtains final product the Chinese medicine for the treatment of periodontitis.
Embodiment 3
By 8g cultivated lands, 8g Fructus Cornis, the 8g fruits of Chinese wolfberry, the 4g root barks of tree peony, 4g Poria cocos, 4g rhizoma alismatis, 1g cooked aconites, 1g Chinese cassia trees, 1g works as
Return, the 1g coptiss, the weight proportion of the 1g dried rhizome of rehmannia is weighed after each taste Chinese medicine, plus the water of 5 times of Chinese medicine gross weight is decocted, waste takes
Soup, obtains final product the Chinese medicine for the treatment of periodontitis.
The clinical testing of Chinese medicine of the present invention is as follows：
Patient：
126 patients with periodontitis are chosen, at 25～64 years old age, men and women half and half.
Treatment method：
Day 1 dose of decocting, 7 days is 1 course for the treatment of, takes 3 courses for the treatment of.
Treatment results：
Reference《Traditional Chinese medicine Clinical Researches of New Drugs guideline》Formulate：
Recovery from illness：Inflammatory resolution, swelling and aching of gum disappear, without inflammatory exudate, oral pocket disappear or shoal (<4mm), alveolar bone
It is in silent oscillation to absorb, and tooth mobility II0 turns I0, and masticatory function improves, and constitutional symptom is released；
It is effective：Inflammatory resolution, swelling and aching of gum disappears substantially, and substantially without inflammatory exudate, oral pocket shoals, absorption of alveolar bone
Situation is stablized, and tooth mobility mitigates, and masticatory function makes moderate progress, and constitutional symptom mitigates；
It is invalid：Symptom, sign slightly mitigate or the person of not being any change.
As a result：Clinical cure 82, effective 36, invalid 8, total effective rate 93.7%.
Embodiment described above is one kind preferably scheme of the present invention, not makees any pro forma to the present invention
Limit, also have other variants and remodeling on the premise of without departing from the technical scheme described in claim.
Claims (3)
1. a kind of Chinese medicine for treating periodontitis, it is characterised in that the Chinese medicine is made up of the flavour of a drug of following weight portion：8～10 parts
Cultivated land, 8～10 portions of Fructus Cornis, 8～10 portions of fruits of Chinese wolfberry, 4～6 parts of root barks of tree peony, 4～6 parts of Poria cocos, 4～6 portions of rhizoma alismatis, 1～3 part is ripe attached
Son, 1～3 portion of Chinese cassia tree, 1～3 part of Radix Angelicae Sinensis, 1～3 portion of coptis, 1～3 part of dried rhizome of rehmannia.
2. it is a kind of it is as claimed in claim 1 treatment periodontitis Chinese medicinal preparation method, it is characterised in that concretely comprise the following steps：Press
Above-mentioned weight is weighed after each taste Chinese medicine, is added water and is decocted, and waste takes soup, obtains final product the Chinese medicine for the treatment of periodontitis.
3. it is according to claim 2 treatment periodontitis Chinese medicinal preparation method, it is characterised in that amount of water be Chinese medicine gross weight
5～10 times of amount.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611135327.5A CN106620074A (en) | 2016-12-11 | 2016-12-11 | Traditional Chinese medicine for treating periodontitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611135327.5A CN106620074A (en) | 2016-12-11 | 2016-12-11 | Traditional Chinese medicine for treating periodontitis and preparation method thereof |
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| CN106620074A true CN106620074A (en) | 2017-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611135327.5A Pending CN106620074A (en) | 2016-12-11 | 2016-12-11 | Traditional Chinese medicine for treating periodontitis and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114306473A (en) * | 2022-02-25 | 2022-04-12 | 山东省千佛山医院 | Composition for tonifying kidney, benefiting qi and activating blood circulation and application thereof in proliferation and differentiation of human periodontal ligament stem cells |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266464A (en) * | 2011-07-11 | 2011-12-07 | 张安美 | Chinese medicinal composition for treating periodontitis |
| CN104383364A (en) * | 2014-11-28 | 2015-03-04 | 侯德润 | Medicine for treating periodontitis and preparation method thereof |
-
2016
- 2016-12-11 CN CN201611135327.5A patent/CN106620074A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266464A (en) * | 2011-07-11 | 2011-12-07 | 张安美 | Chinese medicinal composition for treating periodontitis |
| CN104383364A (en) * | 2014-11-28 | 2015-03-04 | 侯德润 | Medicine for treating periodontitis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 张卓主编: "《疼痛名医诊治绝招大全》", 31 January 2002, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114306473A (en) * | 2022-02-25 | 2022-04-12 | 山东省千佛山医院 | Composition for tonifying kidney, benefiting qi and activating blood circulation and application thereof in proliferation and differentiation of human periodontal ligament stem cells |
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Application publication date: 20170510 |
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