CN111839594A - Lung cancer circulating tumor cell detection device - Google Patents
Lung cancer circulating tumor cell detection device Download PDFInfo
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- CN111839594A CN111839594A CN201910352286.2A CN201910352286A CN111839594A CN 111839594 A CN111839594 A CN 111839594A CN 201910352286 A CN201910352286 A CN 201910352286A CN 111839594 A CN111839594 A CN 111839594A
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- lung cancer
- circulating tumor
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- threaded hole
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- 238000001514 detection method Methods 0.000 title claims abstract description 38
- 206010058467 Lung neoplasm malignant Diseases 0.000 title claims abstract description 24
- 201000005202 lung cancer Diseases 0.000 title claims abstract description 24
- 208000020816 lung neoplasm Diseases 0.000 title claims abstract description 24
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 title claims abstract description 18
- 238000005070 sampling Methods 0.000 claims abstract description 23
- 230000000694 effects Effects 0.000 abstract description 5
- 238000007664 blowing Methods 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000005416 organic matter Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0083—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physiology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a lung cancer circulating tumor cell detection device, and relates to the technical field of medical instruments. This lung cancer circulating tumor cell detection device, one side through detecting the box sets up the expiration sampling subassembly, and set up the fixed breather pipe of three not equidimension in the inside of fixed block, can make the fixed breather pipe of not equidimension adapt to the patient of different states and exhale the sampling action, and then avoid because the patient of different states is when blowing to exhaling the sampling system in, the gas volume of exhalation and the speed of exhalation can be different because of the people's state, thereby can influence ion-molecule reaction, and then show false positive easily, lead to the inaccurate phenomenon of measuring result, and then reach the purpose that improves the device testing effect.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a lung cancer circulating tumor cell detection device.
Background
The lung cancer occurs in bronchial mucosa epithelium, the incidence rate of the lung cancer is remarkably increased in recent 50 years, the incidence rate of the lung cancer is the first place in male malignant tumors in European and American developed countries and in some industrial large cities in China, and the incidence rate of the lung cancer is also rapidly increased in women, and accounts for the 2 nd or 3 rd place of common malignant tumors in women. Lung cancer is a major disease that is dangerous to life and health. In order to effectively treat the early stage of the disease, a lung cancer detection device for in vitro detection is provided.
In the breath organic matter detection method disease auxiliary diagnostic apparatus disclosed in chinese patent application publication CN202649167U, because the amount of exhaled gas and the speed of exhalation are different depending on the state of a person when patients in different states blow air into an exhalation sampling system, ion-molecule reaction is affected, and false positive is easily presented, resulting in inaccurate measurement result.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a lung cancer circulating tumor cell detection device, which solves the problem that when patients in different states blow air into an expiration sampling system, the exhaled air quantity and the exhaled speed are different according to the human state, so that the ion-molecule reaction is influenced, and further false positive is easy to appear, and the measurement result is not accurate.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme:
a lung cancer circulating tumor cell detection device comprises a detection box body, wherein a fixing groove is formed in one side of the detection box body, a first threaded hole is formed in the fixing groove, an expiration sampling assembly is arranged in the fixing groove and comprises a fixing block, a second threaded hole, a fixing bolt, a through hole, a fixing vent pipe, a one-way valve, a gas guide pipe and an air inlet nozzle, the fixing block is arranged in the fixing groove, the second threaded hole is formed in the fixing block, the fixing bolt is arranged in the first threaded hole and the second threaded hole and penetrates through the first threaded hole to the second threaded hole, the fixing block is fixedly installed in the fixing groove through the fixing bolt arranged in the fixing block, the through hole is formed in the fixing block, and the fixing vent pipe is fixedly connected in the through hole, the inside fixed mounting of fixed breather pipe has the check valve, the one end threaded connection who keeps away from the through-hole of fixed breather pipe has the air duct, the one end threaded connection who keeps away from fixed breather pipe of air duct has the suction nozzle.
Optionally, the bottom of the detection box body close to one side of the breath sampling assembly is fixedly connected with a supporting plate, and a through groove is formed in the supporting plate.
Optionally, an air inlet nozzle fixing groove is formed in the inner portion, far away from one side of the detection box body, of the supporting plate, and the air inlet nozzle is lapped inside the air inlet nozzle fixing groove.
Optionally, the bottom of the detection box body is fixedly connected with a supporting seat.
Optionally, one side of the supporting seat, which is far away from the detection box body, is fixedly provided with an anti-slip pad.
Optionally, the number of the through holes is three, and the diameters of the three through holes are different.
(III) advantageous effects
The invention provides a lung cancer circulating tumor cell detection device, which has the following beneficial effects:
(1) this lung cancer circulating tumor cell detection device, one side through detecting the box sets up the expiration sampling subassembly, and set up the fixed breather pipe of three not equidimension in the inside of fixed block, can make the fixed breather pipe of not equidimension adapt to the patient of different states and exhale the sampling action, and then avoid because the patient of different states is when blowing to exhaling the sampling system, the speed of expired gas volume and exhalation can be different because of the people's state, thereby can influence ion-molecule reaction, and then show false positive easily, lead to the inaccurate phenomenon of measuring result, and then reach the purpose that improves the device testing effect.
(2) This lung cancer circulating tumor cell detection device sets up the backup pad through the one side at the detection box to set up logical groove and fixed slot in the inside of backup pad, conveniently settle air duct and suction nozzle, on the other hand through setting up supporting seat and slipmat, is more stable when can making the device place, further improves the device's result of use.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic side view of the inspection box of the present invention;
FIG. 3 is a schematic structural view of a fixing block according to the present invention;
fig. 4 is a schematic structural diagram of the support plate of the present invention.
In the figure: 1-detection box body, 2-fixed groove, 3-first threaded hole, 4-expiration sampling assembly, 401-fixed block, 402-second threaded hole, 403-fixed bolt, 404-through hole, 405-fixed vent pipe, 406-one-way valve, 407-air duct, 408-air inlet nozzle, 5-support plate, 6-through groove, 7-air inlet nozzle fixed groove, 8-support seat and 9-non-slip mat.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
In the present invention, unless otherwise expressly specified or limited, the terms "disposed," "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected or detachably connected; may be a mechanical connection; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Referring to fig. 1-4, the present invention provides a technical solution:
a lung cancer circulating tumor cell detection device comprises a detection box body 1, an expiration organic matter detection method disease auxiliary diagnostic instrument with a structure similar to CN202649167U in the detection box body 1, the detection principle is the same with that, the structure of an expiration sampling assembly is only changed, one side of the detection box body 1 is provided with a fixed groove 2, a first threaded hole 3 is arranged in the fixed groove 2, an expiration sampling assembly 4 is arranged in the fixed groove 2, the expiration sampling assembly 4 comprises a fixed block 401, a second threaded hole 402, a fixed bolt 403, a through hole 404, a fixed vent pipe 405, a one-way valve 406, an air duct 407 and an air inlet nozzle 408, the fixed block 401 is arranged in the fixed groove 2, the second threaded hole 402 is arranged in the fixed block 401, a fixed bolt 403 is arranged in the first threaded hole 3 and the second threaded hole 402, the fixed bolt 403 penetrates through the first threaded hole 3 to the second threaded hole 402, the fixed block 401 is fixedly arranged inside the fixed groove 2 through a fixed bolt 403 arranged inside the fixed block 401, a through hole 404 is arranged inside the fixed block 401, a fixed vent pipe 405 is fixedly connected inside the through hole 404, the three fixed vent pipes 405 have different calibers, the small caliber is suitable for weak physique and the large caliber is suitable for stronger physique, a one-way valve 406 is fixedly arranged inside the fixed vent pipe 405, one end of the fixed vent pipe 405 far away from the through hole 404 is in threaded connection with an air duct 407, one end of the air duct 407 far away from the fixed vent pipe 405 is in threaded connection with an air inlet nozzle 408, the number of the air inlet nozzles 408 is three, the three air ducts 407 are respectively connected, the expiration sampling assembly 4 is arranged on one side of the detection box body 1, and the three fixed vent pipes 405 with different sizes are arranged inside the fixed block 401, so, and then avoid because the patient of different states when blowing in to exhaling the sampling system, the gas volume of exhaling and the speed of exhaling can be different because of the people state to can influence ion-molecule reaction, and then appear false positive easily, lead to the inaccurate phenomenon of measuring result, and then reach the purpose that improves the device detection effect.
As an optional technical scheme of the invention:
the bottom of the detection box body 1 close to one side of the breath sampling assembly 4 is fixedly connected with a supporting plate 5, and a through groove 6 is formed in the supporting plate 5.
As an optional technical scheme of the invention:
the backup pad 5 is kept away from the inside of detecting box 1 one side and has been seted up suction nozzle fixed slot 7, and suction nozzle 408 overlap joint sets up backup pad 5 through the one side at detecting box 1 in the inside of suction nozzle fixed slot 7 to set up logical groove 6 and fixed slot 7 in backup pad 5's inside, can settle air duct 407 and suction nozzle 408.
As an optional technical scheme of the invention:
the bottom of the detection box body 1 is fixedly connected with a supporting seat 8.
As an optional technical scheme of the invention:
one side fixed mounting that detection box 1 was kept away from to supporting seat 8 has slipmat 9, through setting up supporting seat 8 and slipmat 9, more stable when can making the device place, further improves the device's result of use.
As an optional technical scheme of the invention:
the number of the through holes 404 is three, and the diameters of the three through holes 404 are different.
In conclusion, when the lung cancer circulating tumor cell detecting device is used, a user can make the fixed vent pipes 405 with different sizes adapt to patients with different states to carry out breath sampling actions by arranging the breath sampling component 4 at one side of the detecting box body 1 and arranging the three fixed vent pipes 405 with different sizes in the fixed block 401, so that the phenomenon that the exhaled gas quantity and the exhaled speed are different due to human states when the patients with different states blow into the breath sampling system, ion-molecule reaction is influenced, false positive is easy to appear, and the measuring result is inaccurate is avoided, and the purpose of improving the detecting effect of the device is achieved, the supporting plate 5 is arranged at one side of the detecting box body 1, the through groove 6 and the fixed groove 7 are arranged in the supporting plate 5, and the air duct 407 and the air inlet 408 can be arranged, on the other hand, through setting up supporting seat 8 and slipmat 9, more stable when can making the device place, further improve the result of use of the device.
It is noted that in the present disclosure, unless otherwise explicitly specified or limited, a first feature "on" or "under" a second feature may be directly contacted with the first and second features, or indirectly contacted with the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (6)
1. The utility model provides a lung cancer circulating tumor cell detection device, is including detecting box (1), its characterized in that:
the detection box body is characterized in that a fixing groove (2) is formed in one side of the detection box body (1), a first threaded hole (3) is formed in the fixing groove (2), an expiration sampling assembly (4) is arranged in the fixing groove (2), the expiration sampling assembly (4) comprises a fixing block (401), a second threaded hole (402), a fixing bolt (403), a through hole (404), a fixing vent pipe (405), a one-way valve (406), an air guide pipe (407) and an air inlet nozzle (408), the fixing block (401) is arranged in the fixing groove (2), a second threaded hole (402) is formed in the fixing block (401), a fixing bolt (403) is arranged in the first threaded hole (3) and the second threaded hole (402), the fixing bolt (403) penetrates through the first threaded hole (3) to the second threaded hole (402), and the fixing bolt (403) is fixedly arranged in the fixing groove (2) through the fixing bolt (403) arranged in the fixing block (401), through-hole (404) have been seted up to the inside of fixed block (401), the fixed breather pipe of inside fixedly connected with (405) of through-hole (404), the inside fixed mounting of fixed breather pipe (405) has check valve (406), the one end threaded connection who keeps away from through-hole (404) of fixed breather pipe (405) has air duct (407), the one end threaded connection who keeps away from fixed breather pipe (405) in air duct (407) has air inlet nozzle (408).
2. The device for detecting circulating tumor cells of lung cancer according to claim 1,
the bottom fixedly connected with backup pad (5) that detects box (1) and is close to expiration sampling subassembly (4) one side, logical groove (6) have been seted up to the inside of backup pad (5).
3. The device for detecting circulating tumor cells of lung cancer according to claim 2,
an air inlet nozzle fixing groove (7) is formed in the inner portion, far away from one side of the detection box body (1), of the supporting plate (5), and the air inlet nozzle (408) is connected to the inner portion of the air inlet nozzle fixing groove (7) in an overlapping mode.
4. The device for detecting circulating tumor cells of lung cancer according to claim 1,
the bottom of the detection box body (1) is fixedly connected with a supporting seat (8).
5. The device for detecting circulating tumor cells of lung cancer according to claim 4,
and an anti-slip pad (9) is fixedly arranged on one side of the supporting seat (8) far away from the detection box body (1).
6. The device for detecting circulating tumor cells of lung cancer according to claim 1,
the number of the through holes (404) is three, and the diameters of the three through holes (404) are different.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910352286.2A CN111839594A (en) | 2019-04-29 | 2019-04-29 | Lung cancer circulating tumor cell detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910352286.2A CN111839594A (en) | 2019-04-29 | 2019-04-29 | Lung cancer circulating tumor cell detection device |
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| Publication Number | Publication Date |
|---|---|
| CN111839594A true CN111839594A (en) | 2020-10-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910352286.2A Pending CN111839594A (en) | 2019-04-29 | 2019-04-29 | Lung cancer circulating tumor cell detection device |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202649167U (en) * | 2012-07-27 | 2013-01-02 | 中国科学院合肥物质科学研究院 | Exhaled air organic matter detecting method disease auxiliary diagnostic unit |
| CN104749152A (en) * | 2015-04-15 | 2015-07-01 | 哈尔滨医科大学 | Lung cancer circulating tumor cell detection device |
| CN105891459A (en) * | 2016-05-30 | 2016-08-24 | 高举东 | Multifunctional mainstream end-tidal carbon dioxide sensor |
| CN106456007A (en) * | 2014-06-20 | 2017-02-22 | 斯派罗马吉克有限公司 | Medical device for monitoring a physiological pulmonary condition of a user, a mouthpiece for such medical device and method for using such medical device |
| CN206566445U (en) * | 2017-03-10 | 2017-10-20 | 李萍 | A kind of musical respiration training device |
| CN208493128U (en) * | 2018-05-17 | 2019-02-15 | 郑州工程技术学院 | A kind of musical respiration training instrument |
-
2019
- 2019-04-29 CN CN201910352286.2A patent/CN111839594A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202649167U (en) * | 2012-07-27 | 2013-01-02 | 中国科学院合肥物质科学研究院 | Exhaled air organic matter detecting method disease auxiliary diagnostic unit |
| CN106456007A (en) * | 2014-06-20 | 2017-02-22 | 斯派罗马吉克有限公司 | Medical device for monitoring a physiological pulmonary condition of a user, a mouthpiece for such medical device and method for using such medical device |
| CN104749152A (en) * | 2015-04-15 | 2015-07-01 | 哈尔滨医科大学 | Lung cancer circulating tumor cell detection device |
| CN105891459A (en) * | 2016-05-30 | 2016-08-24 | 高举东 | Multifunctional mainstream end-tidal carbon dioxide sensor |
| CN206566445U (en) * | 2017-03-10 | 2017-10-20 | 李萍 | A kind of musical respiration training device |
| CN208493128U (en) * | 2018-05-17 | 2019-02-15 | 郑州工程技术学院 | A kind of musical respiration training instrument |
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Application publication date: 20201030 |