CN202649167U - Exhaled air organic matter detecting method disease auxiliary diagnostic unit - Google Patents
Exhaled air organic matter detecting method disease auxiliary diagnostic unit Download PDFInfo
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- CN202649167U CN202649167U CN201220369342.7U CN201220369342U CN202649167U CN 202649167 U CN202649167 U CN 202649167U CN 201220369342 U CN201220369342 U CN 201220369342U CN 202649167 U CN202649167 U CN 202649167U
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- molecule reaction
- reaction pipe
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Abstract
The utility model provides an exhaled air organic matter detecting method disease auxiliary diagnostic unit which comprises an exhaled air sampling system, an air detecting system and a data processing and computer control system. The air detecting system and the data processing and computer control system are assembled in a machine shell together, the air detecting system is composed of an ion source, an ion-molecule reaction tube and a mass spectra detecting system together, and the exhaled air sampling system is connected with the ion-molecule reaction tube of the air detecting system inside the machine shell through a pipeline. The exhaled air organic matter detecting method disease auxiliary diagnostic unit can achieve auxiliary screening diagnosis for lung cancer, a fatty liver and other diseases by detecting organic matter in exhaled air, and enables health examination to be noninvasive, convenient, rapid and hygienic.
Description
Technical field
The utility model belongs to technical field of medical instruments, is specifically related to a kind of expiration organism detection method disease diagnostic instrument.
Background technology
Along with the mankind's continuous progress and improving constantly of living standard, people emerge in large numbers by the non-invasive diagnosis method that the expiration composition detection diagnoses the illness more and more higher without the demand of wound medical diagnosis on disease thereupon, as: the expiration of helicobacter pylori
13CO
2Detect the expiration H of lactase deficiency
2Detect, the expiration NO of asthma/respiratory tract infection detects, the expiration CO detection of icterus neonatorum etc.
Except containing a large amount of inorganicss, also contain large amount of organic in people's the breath, these organism are related with body metabolism process and health status existence, as: the acetone in the expiration is relevant with metabolism of blood glucose, and ethanol, propyl alcohol etc. are relevant with uremia; Isoprene, acetone, methyl alcohol etc. are relevant with lung cancer.In recent years, the organism by research people breath is related with disease, and the disease auxiliary diagnosis technology of development expiration organism detection more and more comes into one's own.
The disease auxiliary diagnosis technology such as present existing Electronic Nose based on the chromatographic resolution detection, chromatograph-mass spectrometer coupling, but these chromatogram correlation techniques separation detection speeds are slow, can only sample by single-point, waste time and energy, and can not satisfy the demand of real-time online rapid large-scale examination.
The utility model content
Technology of the present utility model is dealt with problems: overcome the deficiencies in the prior art, a kind of expiration organism detection method disease diagnostic instrument is provided, can carry out nothing wound quick diagnosis to lung cancer, fatty liver diseases by the expiration organism feature that detects the people.Accomplished to realize without a break the purpose of many indexs auxiliary diagnosis, made health examination without wound, convenient, health.
The utility model technical solution: a kind of expiration organism detection method disease diagnostic instrument comprises: expiration sampling system, gas detection system, data are processed and computer control system; Wherein the processing of gas detection system and data and computer control system are assembled in the casing jointly; Described gas detection system comprises ion gun, ion-molecule reaction pipe and mass spectrum detection system; The expiration sampling system links to each other with the ion-molecule reaction pipe of gas detection system in the casing by pipeline; Ion gun links to each other with the ion-molecule reaction pipe, communicate by the hole in the chamber of ion gun, ion-molecule reaction pipe, the mass spectrum detection system links to each other with the ion-molecule reaction pipe, communicate by the hole in the chamber of mass spectrum detection system 6 and ion-molecule reaction pipe 5, the output of mass spectrum detection system is connected to data and processes and computer control system.
Two holes between described connection ion gun, ion-molecule reaction pipe and mass spectrum detection system three's cavity are coaxial cables, and the aperture is 0.1mm ~ 15mm.Three's internal cavity is the infrabar state during work, and the ion gun internal gas pressure is at 10Pa ~ 200Pa, and the ion-molecule reaction intraductal atmospheric pressure is at 30Pa ~ 300Pa, mass spectrum detection system internal gas pressure＜10
-4Pa.
Use of the present utility model and the course of work are as follows: the testee is with the blow gun of tight-lipped subsides expiration sampling system, slowly gas in the lung all is blown into the expiration sampling system, time remaining is greater than 7s, system shunts the gas detection system of one road gas in pipeline enters casing, the parent ion generation ion-molecule reaction that the exhalation organism produces with ion gun in reaction tube, thereby become ion, finally surveyed by the mass spectrum detection system, after data processing and computer control system, provide disease auxiliary diagnosis result at screen.
The utility model advantage compared with prior art is as follows:
(1) the utility model is simple to operate, convenient, and without wound, health.
(2) the utility model sample introduction of can once exhaling carries out auxiliary diagnosis to lung cancer, fatty liver simultaneously.
(3) the utility model is perfect by the exhalation data storehouse, also may carry out non-invasive diagnosis to other diseases.
Description of drawings
Fig. 1 is theory diagram of the present utility model;
Fig. 2 is schematic appearance of the present utility model.
Embodiment
As shown in Figure 1, the utility model embodiment comprises: comprising: expiration sampling system 1, gas detection system 2, data are processed and computer control system 3; Wherein the processing of gas detection system 2 and data and computer control system 3 are assembled in the casing jointly; Described gas detection system 2 comprises ion gun 4, ion-molecule reaction pipe 5 and mass spectrum detection system 6; Expiration sampling system 1 links to each other with the ion-molecule reaction pipe 5 of gas detection system 2 in the casing by pipeline; Ion gun 4 links to each other with ion-molecule reaction pipe 5, communicates by aperture in the chamber, and mass spectrum detection system 6 links to each other with ion-molecule reaction pipe 5, communicates by aperture in the chamber, and 6 outputs of mass spectrum detection system are connected to data and process and computer control system 3.
Two apertures between connection ion gun 4, ion-molecule reaction pipe 5 and mass spectrum detection system 6 threes' cavity are coaxial cables, and the aperture is 0.1mm ~ 15mm, play the effect of difference vacuum and transmission ion.Three's internal cavity is the infrabar state during work, and the ion gun internal gas pressure is at 10Pa ~ 200Pa, and the ion-molecule reaction intraductal atmospheric pressure is at 30Pa ~ 300Pa, mass spectrum detection system internal gas pressure＜10
-4Pa, the infrabar state is kept by mechanical pump and molecular pump system.
As shown in Figure 2, the left side is described expiration sampling system 1, and the right side is host machine part, and inside is integrated, and gas detection system 2 and data are processed and computer control system 3.During detection, the testee is with the blow gun of tight-lipped subsides expiration sampling system 1, slowly gas in the lung all is blown in the expiration sampling system 1, time remaining is greater than 7s, expiration sampling system 1 is by the gas detection system 2 of gas in pipeline enters casing, breath becomes ion with reactive ion generation ion-molecule reaction that ion gun 4 produces in the ion-molecule reaction pipe 5 of gas detection system 2, finally surveyed by mass spectrum detection system 6, after data processing and computer control system 3, provide lung cancer, fatty liver diseases auxiliary diagnosis result at screen.
Claims (3)
1. an expiration organism detection method disease diagnostic instrument is characterized in that comprising: expiration sampling system (1), gas detection system (2), data processing and computer control system (3); Wherein the processing of gas detection system (2) and data and computer control system (3) are assembled in the casing jointly; Described gas detection system (2) comprises ion gun (4), ion-molecule reaction pipe (5) and mass spectrum detection system (6); Expiration sampling system (1) links to each other with the ion-molecule reaction pipe (5) of gas detection system (2) in the casing by pipeline; Ion gun (4) links to each other with ion-molecule reaction pipe (5), and communicates by the hole in the chamber of ion gun (4) and ion-molecule reaction pipe (5); Mass spectrum detection system (6) links to each other with ion-molecule reaction pipe (5), and communicates by the hole in the chamber of mass spectrum detection system (6) and ion-molecule reaction pipe (5); Mass spectrum detection system (6) output is connected to data and processes and computer control system (3).
2. a kind of expiration organism detection method disease diagnostic instrument according to claim 1, it is characterized in that: two holes between described connection ion gun (4), ion-molecule reaction pipe (5) and mass spectrum detection system (6) three's cavity are coaxial cables, and the aperture is 0.1mm ~ 15mm.
3. a kind of expiration organism detection method disease diagnostic instrument according to claim 1 and 2, it is characterized in that: during work, ion gun (4) internal gas pressure is 10Pa ~ 200Pa, and ion-molecule reaction pipe (5) internal gas pressure is 30Pa ~ 300Pa, mass spectrum detection system internal gas pressure＜10
-4Pa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220369342.7U CN202649167U (en) | 2012-07-27 | 2012-07-27 | Exhaled air organic matter detecting method disease auxiliary diagnostic unit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220369342.7U CN202649167U (en) | 2012-07-27 | 2012-07-27 | Exhaled air organic matter detecting method disease auxiliary diagnostic unit |
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|---|---|
| CN202649167U true CN202649167U (en) | 2013-01-02 |
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| CN201220369342.7U Expired - Lifetime CN202649167U (en) | 2012-07-27 | 2012-07-27 | Exhaled air organic matter detecting method disease auxiliary diagnostic unit |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202696A (en) * | 2013-03-06 | 2013-07-17 | 王胜昱 | Modeling method for detecting lung diseases through expiratory air on basis of aerosol |
| CN104713989A (en) * | 2015-02-04 | 2015-06-17 | 中国科学院合肥物质科学研究院 | Mixing chamber technology-based gas metabolism detection apparatus and method thereof |
| CN106066348A (en) * | 2016-08-23 | 2016-11-02 | 武汉和生科技有限公司 | Hospital blood sugar test instrument and noninvasive management system |
| WO2019084953A1 (en) * | 2017-11-02 | 2019-05-09 | 王健 | Ion counting detection device for tumor-related molecules, and using method therefor |
| CN111839594A (en) * | 2019-04-29 | 2020-10-30 | 首都医科大学附属北京胸科医院 | Lung cancer circulating tumor cell detection device |
| CN112730842A (en) * | 2020-12-22 | 2021-04-30 | 中国科学院合肥物质科学研究院 | Auxiliary diagnosis instrument for high triglyceride blood disease expiration screening and application thereof |
| CN116525404A (en) * | 2023-04-13 | 2023-08-01 | 广东智普生命科技有限公司 | Ion source for nasal exhalation on-line analysis, exhalation detection system and detection method |
-
2012
- 2012-07-27 CN CN201220369342.7U patent/CN202649167U/en not_active Expired - Lifetime
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202696A (en) * | 2013-03-06 | 2013-07-17 | 王胜昱 | Modeling method for detecting lung diseases through expiratory air on basis of aerosol |
| CN103202696B (en) * | 2013-03-06 | 2014-12-17 | 王胜昱 | Modeling method for detecting lung diseases through expiratory air on basis of aerosol |
| CN104713989A (en) * | 2015-02-04 | 2015-06-17 | 中国科学院合肥物质科学研究院 | Mixing chamber technology-based gas metabolism detection apparatus and method thereof |
| CN104713989B (en) * | 2015-02-04 | 2016-08-17 | 中国科学院合肥物质科学研究院 | A kind of gaseous metabolism based on mixing chamber technology detection device and method |
| CN106066348A (en) * | 2016-08-23 | 2016-11-02 | 武汉和生科技有限公司 | Hospital blood sugar test instrument and noninvasive management system |
| WO2019084953A1 (en) * | 2017-11-02 | 2019-05-09 | 王健 | Ion counting detection device for tumor-related molecules, and using method therefor |
| US10859530B2 (en) | 2017-11-02 | 2020-12-08 | Jian Wang | Detection device for ion count in tumor-related molecules and usage method thereof |
| CN111839594A (en) * | 2019-04-29 | 2020-10-30 | 首都医科大学附属北京胸科医院 | Lung cancer circulating tumor cell detection device |
| CN112730842A (en) * | 2020-12-22 | 2021-04-30 | 中国科学院合肥物质科学研究院 | Auxiliary diagnosis instrument for high triglyceride blood disease expiration screening and application thereof |
| CN116525404A (en) * | 2023-04-13 | 2023-08-01 | 广东智普生命科技有限公司 | Ion source for nasal exhalation on-line analysis, exhalation detection system and detection method |
| CN116525404B (en) * | 2023-04-13 | 2024-02-20 | 广东智普生命科技有限公司 | Ion source for nasal exhalation on-line analysis, exhalation detection system and detection method |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130102 |