WO2020038050A1

WO2020038050A1 - Respiratory frequency acquisition method and apparatus for oxygen uptake monitoring

Info

Publication number: WO2020038050A1
Application number: PCT/CN2019/089908
Authority: WO
Inventors: 王乾隆; 王涛; 邓清娟; 彭彰国
Original assignee: 广州康智件科技有限公司
Priority date: 2018-08-24
Filing date: 2019-06-04
Publication date: 2020-02-27
Also published as: CN109276788A

Abstract

Disclosed are a respiratory frequency acquisition method and apparatus for oxygen uptake monitoring. The method comprises: step one, acquiring respiratory sound data of a mouth and/or nose, and transmitting the respiratory sound data of the mouth and/or nose to a controller; step two, acquiring ambient sound data of the mouth and/or nose, and transmitting the ambient sound data of the mouth and/or nose to the controller; and step three, removing data, in the respiratory sound data of the mouth and/or nose, with the same waveform as the ambient sound data of the mouth and/or nose by means of cross comparison, so as to obtain actual respiratory sound data of the mouth and/or nose. Comparison denoising is carried out using the respiratory sound data and the ambient sound data, and precise respiratory sound data can then be obtained by means of analysis and comparison carried out by the controller, thereby obtaining respiratory frequency data.

Description

Breathing frequency acquisition method and device for oxygen inhalation monitoring

Technical field

The invention relates to the technical field of oxygen therapy monitoring equipment, in particular to a breathing frequency acquisition method and device for monitoring oxygen inhalation.

Background technique

The main purpose of oxygen therapy is to correct hypoxemia in the human body, reduce respiratory work and reduce heart load, prevent and reverse tissue damage and organ dysfunction caused by hypoxia, and at the same time try to maintain the patient's mobility. The main risks of oxygen therapy are inability to effectively correct hypoxemia, increase carbon dioxide retention, and even oxygen poisoning. The standard oxygen treatment principle is to ensure its safety and effectiveness. There are two well-known international controlled clinical trials that can clearly prove the effectiveness and corresponding conditions of home oxygen therapy, and they are also the scientific basis for incorporating home oxygen therapy into national health protection systems in many countries.

In the 1970s, the National Institutes of Health (NIH) Night Oxygen Therapy (NOTT) and the British Medical Research Council Clinical Trials (MRC) studies showed improvements in the five-year survival rate of COPD patients with chronic hypoxemia and daily oxygen therapy. The duration (hours) is directly proportional. Patients who did not receive adjuvant oxygen therapy had the worst survival rate; patients who received 12 to 15 hours of oxygen therapy per day had better survival rates; patients who received mobile oxygen system for nearly 24 hours of continuous oxygen therapy had the worst survival rate. Ok.

The American Thoracic Society (ATS), the European Respiratory Society (ERS), the National Institute of Health and Clinical Optimization (NICE) and other countries have clearly formulated the home oxygen therapy prescription standards and treatment goals in the treatment guidelines. The authoritative textbooks for medical treatment in China also include oxygen therapy indications and indications in the textbook of Internal Medicine. The core content of the national guidelines is similar to the standards set by the American Thoracic Society (ATS). In the course of COPD disease, hypoxemia or COPD with stable exacerbation of arterial oxygen pressure PaO ₂ <55mmHg or arterial oxygen saturation SaO ₂ <88% or arterial oxygen pressure PaO ₂ = 55-59mmHg Accompanied by pulmonary heart disease, erythrocytosis, pulmonary hypertension and so on. Treatment goals: PaO ₂ > 60mmHg (SaO ₂ > 90%) is guaranteed during rest, sleep, and activities, and the daily oxygen intake time is more than 15 hours, preferably 18-24 hours.

According to relevant literature at home and abroad, in terms of compliance and treatment effects, oxygen management quality management methods are generally lacking, and monitoring results are relatively poor. The main manifestations are: whether the patient is inhaling oxygen, how long the oxygen is inhaled, how much flow, whether he or she has followed the doctor's order, how effective the patient is inhaling oxygen (blood oxygen saturation, breathing rate, improvement of symptoms, mental state, appetite, etc.)

Aiming at the above problems, the present invention focuses on solving the real-time monitoring problems such as whether to inhale oxygen, oxygen inhalation time, and breathing frequency. In particular, clinical studies have shown that monitoring of respiratory frequency variability can effectively predict the acute onset of COPD and provide an effective means for early intervention.

European Patent Office patent number filed by French SRETT company: EP3146 897 A1, a technology used to solve the problem of judging breathing frequency and oxygen flow measurement during nasal catheter oxygen inhalation. The proposed solution is two MEMS microphones, A MEMS pressure sensor and an environmental pressure sensor, combined with a flow blocking structure using computational fluid dynamics (CFD), using a differential circuit, a filter circuit, a breathing frequency, a flow calculation circuit, etc., to obtain the patient's breathing frequency and oxygen flow .

This solution has the following shortcomings: 1. Because the signal of pressure change caused by breathing is weak, the sensor needs to be selected to meet the high precision requirements; 2. Because of the large amount of sampling calculations and the need for energy saving and power saving of the device, Or DSP processor selection needs are high; 3. The above factors 1, 2 will lead to increased costs, which is not conducive to promotion and application.

Summary of the Invention

An object of the present invention is to provide a method for collecting respiratory frequency with high accuracy for oxygen inhalation monitoring.

Another object of the present invention is to provide a breathing frequency acquisition device with high accuracy for oxygen inhalation monitoring.

To achieve the above objective, the present invention adopts the following technical solutions:

Provided is a breathing frequency acquisition method for oxygen inhalation monitoring, including

Step 1: Collect respiratory sound data of the mouth and / or nose, and transmit the respiratory sound data of the mouth and / or nose to the controller;

Step 2: Collect ambient sound data of the mouth and / or nose, and transmit the ambient sound data of the mouth and / or nose to the controller;

Step 3: After the difference comparison is performed, the data of the same waveform as the ambient sound data of the mouth and / or nose is removed from the respiratory sound data of the mouth and / or nose to obtain the actual breath of the mouth and / or nose Sound data.

Wherein, the collecting the breathing sound data of the mouth and / or the nose includes collecting the breathing sound data of the mouth and / or the nose through the breathing sound catheter and a microphone, and the microphone receiving section of the breathing sound catheter Located on the mouth and / or nose.

Wherein, collecting the ambient sound data of the mouth and / or the nose includes the ambient sound pipe and the microphone, and the microphone collects the ambient sound data of the mouth and / or the nose through the environment sound pipe, and the sound receiving part of the ambient sound pipe is located at Near the sound receiver of the breathing sound tube.

Another object of the present invention is achieved by the following scheme:

Respiratory frequency acquisition device for oxygen inhalation monitoring, including

Nasal catheter for supplying oxygen to a patient;

An oxygen line, which communicates with a nasal cannula for supplying oxygen;

Respiratory sound collection mechanism for collecting breathing sounds of the mouth and / or nose;

Oxygen flow monitoring mechanism; one end is connected to the oxygen pipeline and the other end is connected to the nasal catheter, and the oxygen is output to the nasal catheter through the oxygen pipeline through the oxygen circulation monitoring mechanism;

Respiratory ambient sound collection mechanism for collecting ambient sound data of the mouth and / or nose;

The controller receives the respiratory sound data and the ambient sound data, compares the respiratory sound data with the ambient sound data, obtains the actual respiratory sound data, and calculates the breathing frequency.

Wherein, the breathing sound collecting mechanism includes a detection body, and the body is provided with a breathing sound detection signal inlet for collecting respiratory sounds of the nose and / or mouth, and further includes a sound monitoring microphone for detecting the nose and And / or the breathing sound at the mouth, transmitting the breathing sound data to the controller; the detection body is set as a pipe body, the breathing sound detection signal inlet is set on the pipe body, the pipe body is extended through the pipe, and the sound monitoring microphone is set on the place The pipeline is used for collecting respiratory sound data transmitted by the pipeline, and the monitoring body is provided with a baffle for collecting and amplifying the nasal and / or mouth breathing airflow, and the breathing sound detection signal inlet is provided at The baffle is on the detection body on the side facing the user.

Wherein, the breathing ambient sound collecting mechanism includes an environmental sound collecting duct and an environmental sound collecting microphone, which collects environmental sounds, and the environmental sound collecting microphone recognizes the environmental noise data transmitted by the sound collecting catheter and sends it to the controller.

The upper part of the detection body is provided with an environmental sound inlet for collecting and amplifying environmental sounds. The sound receiving end of the environmental sound tube and the environmental sound inlet are connected through an environmental sound pipe.

Wherein, the controller includes an amplifier, a subtractor, a comparator, a microcontroller, and a data analysis module connected to the microcontroller, which are electrically connected in sequence, and the breathing sound of the mouth and / or nose of the breathing sound collection mechanism The data is sequentially transmitted to the microcontroller through an amplifier, a subtractor, and a comparator, and the ambient sound data of the mouth and / or nose of the breathing ambient sound acquisition mechanism is sequentially transmitted to the microcontroller through an amplifier, a subtractor, and a comparator. The data analysis module compares and analyzes the ambient sound data with the number of breathing sounds of the mouth and / or nose, and transmits the analysis result to the microcontroller, and the microcontroller calculates the breathing frequency data.

It also includes a storage module for storing the digital audio signals obtained by the analog-to-digital converter and the analysis results of the data analysis module.

Among them, a Bluetooth module and a display module are also included. The Bluetooth module is used for transmitting the respiratory frequency data obtained by the microcontroller to the display module for display.

Beneficial effects:

A breathing frequency acquisition method for oxygen inhalation monitoring, including

The present invention uses respiratory sound data and ambient sound data to perform contrast denoising, and then uses a controller to analyze and compare to obtain accurate respiratory sound data, thereby obtaining respiratory frequency data.

BRIEF DESCRIPTION OF THE DRAWINGS

The drawings described here are used to provide a further understanding of the invention and constitute a part of the present application. The exemplary embodiments of the present invention and the description thereof are used to explain the present invention, and do not constitute an improper limitation on the invention.

FIG. 1 is a schematic structural diagram of a breathing frequency acquisition device for oxygen monitoring according to an embodiment of the present invention; FIG.

FIG. 2 is a schematic structural diagram of a breathing sound acquisition mechanism without a nasal catheter connected to a breathing frequency acquisition device for oxygen monitoring according to the present invention.

FIG. 3 is a schematic structural diagram of a breathing sound collection mechanism connected to a nasal tube of a breathing frequency collection device for oxygen monitoring according to the present invention.

FIG. 4 is a schematic structural diagram of an oxygen flow monitoring mechanism of a breathing frequency acquisition device for oxygen inhalation monitoring according to the present invention.

FIG. 5 is a schematic structural diagram of a controller of a breathing frequency acquisition device for oxygen monitoring according to the present invention.

Reference signs:

1-nasal catheter, 2-oxygen line,

3——Respiratory sound collection mechanism

301-detection body, 302-breathing sound detection signal entrance, 303-sound monitoring microphone, 304-bezel, 305-snap, 306-connecting ear

4——Oxygen flow monitoring agency

401-monitoring body, 402-oxygen inlet, 403-oxygen outlet,

404-first intake chamber, 405-second intake chamber, 406-one-way valve,

407——Oxygen monitoring microphone,

408——sound monitoring microphone placement cavity, 409——connecting air port;

5——Noise monitoring module

501-ambient radio conduit, 502-ambient radio microphone, 503-ambient radio entrance, 504-ambient radio pipeline.

detailed description

The technical solution provided by the present invention is described in more detail below with reference to the drawings.

Embodiment 1 is shown in FIG. 1 to FIG. 5.

Nasal catheter 1 for inputting oxygen to a patient;

An oxygen line 2 is connected to the nasal catheter 1 for supplying oxygen;

Breath sound collection mechanism 3, for collecting breathing sounds of the nose and mouth;

Oxygen flow monitoring mechanism 4; one end is connected to oxygen line 2 and the other end is connected to nasal tube 1, and oxygen is output to nasal tube 1 through oxygen line 2 through oxygen flow monitoring device 4;

The present invention uses a sound acquisition method. The present invention uses respiratory sound data and ambient sound data to perform contrast denoising, and then uses a controller to analyze and compare to obtain accurate respiratory sound data, and then obtain respiratory frequency data.

Specifically, the oxygen source supplies oxygen to the patient through the oxygen line 2 and the nasal catheter 1. The user uses the nasal and / or mouth to exhale airflow, and the airflow enters the detection body 301 through the breathing sound detection signal inlet 302, and the breathing sound detection signal The diameter of the inlet 302 is small. When the airflow passes through, it will generate sound in the detection body. The sound monitoring microphone 303 recognizes these sound data and transmits it to the controller to calculate the breathing frequency.

The method of sound collection avoids the complexity of conventional pressure detection. This is because the oxygen output port is open during the oxygen inhalation of the nasal catheter 1, the pressure change in the oxygen pipeline 2 is extremely small, and the pressure sensor is detecting In the process, it is extremely susceptible to external interference, which makes the judgment inaccurate.

The breathing sound collection mechanism 3 includes a detection body 301, and the body is provided with a breathing sound detection signal inlet 302 for collecting breathing sounds of the nose and nose, and further includes a sound monitoring microphone 303 for detecting breathing of the nose and nose Sound, transmitting breathing sound data to the controller.

The baffle 304 is fixed to the detection body 301 for blocking the nasal airflow, and the breathing sound detection signal inlet 302 is provided on the detection body 301 on the side of the baffle 304 facing the user. The baffle 304 can effectively obstruct airflow, obstruct the airflow, and conduct it downward into the breathing sound detection signal inlet 302, which improves the efficiency of obtaining breathing sound. The height of the baffle 304 is 0.5 to 3 cm. The baffle 304 is cat-ear shaped.

As shown in FIG. 2, the present invention can also transmit sound to the end through the form of a tube, reducing the number of parts of the nose and nose. The power connection of the sound monitoring microphone 303 can also be integrated at the other end of the tube, that is, The end of the tube far from the patient's use site effectively reduces the psychological burden on the user.

The detection body 301 is provided as a pipe body, and a breathing sound detection signal inlet 302 is provided on the pipe body. The pipe body is extended by a pipe, and a sound monitoring microphone 303 is provided on the pipe for collecting breathing sound data transmitted by the pipe. .

As shown in FIG. 3, the breathing sound collecting mechanism 3 of the present invention can also be integrated on the existing nasal catheter 1 to enhance the use effect. The pipe body is provided with a buckle 305, and the buckle 305 is buckled on the The nasal catheter 1 is fixed to the nasal catheter 1 on the pipeline. Can effectively reduce the nasal parts, easy to use.

The tube body is provided with two connecting ears 306. When the detection body 301 is connected to the nasal catheter 1, the two connecting ears 306 are respectively sleeved on the two protruding portions of the nasal catheter 1. Easy to fix the detection body 301 fixed to the nasal cannula 1.

There are two breathing sound detection signal inlets 302 provided, and the body 301 is provided and detected corresponding to the nostril position, respectively.

As shown in FIG. 4 of the present invention,

The oxygen flow monitoring mechanism 4 is provided with a monitoring body 401. The monitoring body 401 is provided with an oxygen inlet 402, an oxygen outlet 403, a first inlet cavity 404, and a second inlet cavity 405. A check valve 406 is provided at a position where the air cavity 404 communicates with the second air inlet cavity 405.

The monitoring body 401 is provided with a sound monitoring microphone placement cavity 408, and the sound monitoring microphone placement cavity 408 is provided with a connection air port 409. The connection air port 409 is connected to the pipe body through a pipeline, and the respiratory sound data is transmitted to the sound monitoring microphone placement cavity 408 through the connection air port.

The microphone of the breathing sound collection mechanism 3 is disposed in the first intake cavity 404 of the monitoring body 401. The microphone is disposed in the first intake cavity 404. The one-way valve 406 can effectively block the sound of the airflow of oxygen from being transmitted to the first intake cavity 404, which affects the microphone to collect oxygen output sound data.

Wherein, the breathing ambient sound collecting mechanism includes an environmental sound collecting duct 501 and an environmental sound collecting microphone 502 to collect environmental sounds. The environmental sound collecting microphone 502 recognizes and transmits the environmental noise data transmitted by the sound collecting catheter 501 to the controller.

The ambient radio sound entrance 503 is located outside the detection body 301 and is at the same level or near the horizontal plane as the breathing sound detection signal entrance 302 to maintain the consistency of its collected sound and improve the radio consistency.

The upper part of the detection body 301 is provided with an environmental sound inlet 503 for collecting and amplifying environmental sounds. The sound receiving end of the environmental sound tube 501 and the environmental sound inlet 503 are connected through an environmental sound pipe 504.

The ambient sound collection pipeline 504 is located at the upper part of the detection body 301, and the breathing sound collection pipeline is located at the lower part of the detection body 301. The sound source inlets connected to it are opposite in position, one inside and one outside, which improves the accuracy of each individual sound collection. When interference occurs, the difference in the common frequency part is not too large, which improves the accuracy and effectively reduces the difficulty of subsequent controller analysis.

Wherein, it also includes a storage module, which is used to store the digital audio signal obtained by the analog-to-digital converter and the analysis result of the data analysis module.

In the description of the present invention, it should be understood that the terms “center”, “portrait”, “horizontal”, “front”, “rear”, “left”, “right”, “vertical”, “horizontal”, “ The orientations or positional relationships indicated by "top", "bottom", "inside", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and are not intended to indicate or imply The device or element referred to must have a specific orientation, structure and operation for a specific orientation, and therefore cannot be understood as a limitation on the protection content of the present invention.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention, rather than limiting them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that they can still The technical solutions described in the foregoing embodiments are modified, or some technical features are equivalently replaced, but these modifications or replacements do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

A breathing frequency acquisition method for oxygen inhalation monitoring, characterized in that:

Step 1: Collect respiratory sound data of the mouth and / or nose, and transmit the respiratory sound data of the mouth and / or nose to the controller;

Step 2: Collect ambient sound data of the mouth and / or nose, and transmit the ambient sound data of the mouth and / or nose to the controller;

Step 3: After the cross-contrast comparison, remove the data of the same waveform as the ambient sound data of the mouth and / or nose from the respiratory sound data of the mouth and / or nose to obtain the actual breath sound of the mouth and / or nose data.
The breathing frequency acquisition method for oxygen inhalation monitoring according to claim 1, characterized in that: said collecting respiratory sound data of the mouth and / or nose includes passing a breathing sound tube and a microphone, and the microphone passes The breathing sound tube collects the breathing sound data of the mouth and / or the nose, and the sound receiving part of the breathing sound tube is located at the mouth and / or the nose.
The breathing frequency acquisition method for oxygen inhalation monitoring according to claim 2, characterized in that: collecting ambient sound data of the mouth and / or nose, including passing through an environmental sounding catheter and a microphone, and the microphone passes through the environment The sound collection tube collects ambient sound data of the mouth and / or nose, and the sound collection portion of the environment sound collection tube is located near the sound collection portion of the breathing sound tube.
A breathing frequency acquisition device for oxygen inhalation monitoring, characterized in that:

Nasal catheter for supplying oxygen to a patient;

An oxygen line, which communicates with a nasal cannula for supplying oxygen;

Respiratory sound collection mechanism for collecting breathing sounds of the mouth and / or nose;

Oxygen flow monitoring mechanism; one end is connected to the oxygen pipeline and the other end is connected to the nasal catheter, and the oxygen is output to the nasal catheter through the oxygen pipeline through the oxygen circulation monitoring mechanism;

Respiratory ambient sound collection mechanism for collecting ambient sound data of the mouth and / or nose;

The controller receives the respiratory sound data and the ambient sound data, compares the respiratory sound data with the ambient sound data, obtains the actual respiratory sound data, and calculates the breathing frequency.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 4, characterized in that the breathing sound collection mechanism comprises a detection body, and the body is provided with a breathing sound detection signal inlet for collecting the nose And / or mouth breathing sound, further comprising a sound monitoring microphone for detecting the breathing sound of the nose and / or mouth, and transmitting the breathing sound data to the controller; the detection body is set as a pipe body, and the breathing sound The detection signal inlet is provided on the pipe body, and the pipe body is extended through the pipe. The sound monitoring microphone is provided on the pipe for collecting breathing sound data transmitted by the pipe. The monitoring body is provided with a baffle for Collecting and amplifying the nasal and / or mouth breathing airflow, the breathing sound detection signal inlet is provided on the detection body of the side of the baffle facing the user.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 5, characterized in that: the breathing ambient sound collection mechanism comprises an environmental sound collecting catheter and an ambient sound collection microphone head, which collects ambient sound, and the ambient sound collection microphone The head recognizes and transmits the environmental noise data transmitted from the sound tube to the controller.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 6, characterized in that: an upper part of the detection body is provided with an environmental sound inlet for collecting and amplifying environmental sounds, The radio terminal is connected to the ambient radio inlet through an ambient radio pipeline.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 5, characterized in that the controller comprises an amplifier, a subtractor, a comparator, a microcontroller, and a microcontroller connected electrically in sequence. Data analysis module, the respiratory sound data of the mouth and / or nose of the breathing sound acquisition mechanism is transmitted to the microcontroller through an amplifier, a subtractor, and a comparator in sequence, and the mouth of the breathing sound acquisition mechanism and / Or the ambient sound data of the nose is sequentially transmitted to the microcontroller through the amplifier, subtractor, and comparator, and the data analysis module compares and analyzes the ambient sound data with the number of breathing sounds of the mouth and / or nose, and transmits the analysis result to Microcontroller, the microcontroller calculates the breathing frequency data.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 8, further comprising a storage module, wherein the storage module is configured to store digital audio signals and data analysis modules obtained by an analog-to-digital converter. Analyze the results.
The breathing frequency acquisition device for oxygen inhalation monitoring according to claim 8, further comprising a Bluetooth module and a display module, wherein the Bluetooth module is configured to transmit the breathing frequency data obtained by the microcontroller to the display The module is displayed.