CN111801107A - 用于调节炎性肠病的细菌噬菌体 - Google Patents

用于调节炎性肠病的细菌噬菌体 Download PDF

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Publication number
CN111801107A
CN111801107A CN201880071574.4A CN201880071574A CN111801107A CN 111801107 A CN111801107 A CN 111801107A CN 201880071574 A CN201880071574 A CN 201880071574A CN 111801107 A CN111801107 A CN 111801107A
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CN
China
Prior art keywords
kp2w
kp2m
kp3w
lytic
bacteriophage
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Pending
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CN201880071574.4A
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English (en)
Chinese (zh)
Inventor
本田贤也
新幸二
成岛圣子
伊兰·依琳娜芙
罗特姆·索里克
埃弗拉特·卡布拉
哈瓦·本大卫
埃亚勒·魏因斯托克
莎拉·波洛克
尤利娅·穆图欣
内奥米·扎克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Byomax Ltd
Yeda Research and Development Co Ltd
Keio School Corp
Original Assignee
Byomax Ltd
Yeda Research and Development Co Ltd
Keio School Corp
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Filing date
Publication date
Application filed by Byomax Ltd, Yeda Research and Development Co Ltd, Keio School Corp filed Critical Byomax Ltd
Publication of CN111801107A publication Critical patent/CN111801107A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201880071574.4A 2017-09-08 2018-09-07 用于调节炎性肠病的细菌噬菌体 Pending CN111801107A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762555790P 2017-09-08 2017-09-08
US62/555,790 2017-09-08
PCT/IB2018/001128 WO2019048930A2 (en) 2017-09-08 2018-09-07 BACTERIOPHAGE OF MODULATION OF INFLAMMATORY INTESTINAL DISEASE

Publications (1)

Publication Number Publication Date
CN111801107A true CN111801107A (zh) 2020-10-20

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Family Applications (1)

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CN201880071574.4A Pending CN111801107A (zh) 2017-09-08 2018-09-07 用于调节炎性肠病的细菌噬菌体

Country Status (7)

Country Link
US (1) US20220031776A1 (enExample)
EP (2) EP3678639B1 (enExample)
JP (1) JP2020533408A (enExample)
CN (1) CN111801107A (enExample)
AU (1) AU2018330848A1 (enExample)
CA (1) CA3074406A1 (enExample)
WO (1) WO2019048930A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115558650A (zh) * 2022-10-09 2023-01-03 优宜邦生物科技(上海)有限公司 一种宽宿主谱变栖克雷伯氏菌噬菌体及其应用和制剂
CN118318913A (zh) * 2024-05-09 2024-07-12 江苏省农业科学院 一种含有噬菌体的新型饲料添加剂及其应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3796781A4 (en) * 2018-05-23 2022-04-20 Brigham Young University BACTERIOPHAGE COMPOSITIONS AND KITS AND METHODS
US11986502B2 (en) 2018-05-23 2024-05-21 Optium, LLC Bacteriophage compositions and kits and related methods
CA3131316A1 (en) 2019-03-07 2020-09-10 Keio University Bacteriophage for modulating inflammatory bowel disease
US20240075084A1 (en) * 2021-01-21 2024-03-07 Biomx Ltd. Klebsiella bacteriophage and uses thereof
MX2023012454A (es) * 2021-04-22 2023-10-31 Ferring Bv Terapia con bacteriofagos contra escherichia coli adherente-invasiva.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160143965A1 (en) * 2013-04-30 2016-05-26 Ferring B.V. Bacteriophage therapy
CN106754745A (zh) * 2016-11-29 2017-05-31 江苏省农业科学院 一种肺炎克雷伯氏菌噬菌体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160143965A1 (en) * 2013-04-30 2016-05-26 Ferring B.V. Bacteriophage therapy
CN106754745A (zh) * 2016-11-29 2017-05-31 江苏省农业科学院 一种肺炎克雷伯氏菌噬菌体及其应用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KOJI ATARASHI等: "Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation", 《SCIENCE》 *
MATTHIEU GALTIER等: "Bacteriophages targeting adherent invasing Escherichia coli strains as a promising new treatment for Crohn"s disease", 《JOURNAL OF CROHN"S AND COLITIS》 *
TAHA RASHID等: "The Role of Klebsiella in Crohn"s Disease with a potential for the use of Antimicrobial Measures", 《INTERNATIONAL JOURNAL OF RHEUMATOLOGY》 *
高晶等: "肺炎克雷伯菌噬菌体的生物学特性和基因组学研究", 《中华医学会会议论文集》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115558650A (zh) * 2022-10-09 2023-01-03 优宜邦生物科技(上海)有限公司 一种宽宿主谱变栖克雷伯氏菌噬菌体及其应用和制剂
CN115558650B (zh) * 2022-10-09 2023-05-30 优宜邦生物科技(上海)有限公司 一种宽宿主谱变栖克雷伯氏菌噬菌体及其应用和制剂
CN118318913A (zh) * 2024-05-09 2024-07-12 江苏省农业科学院 一种含有噬菌体的新型饲料添加剂及其应用

Also Published As

Publication number Publication date
WO2019048930A2 (en) 2019-03-14
EP4032526A1 (en) 2022-07-27
JP2020533408A (ja) 2020-11-19
CA3074406A1 (en) 2019-03-14
AU2018330848A1 (en) 2020-03-12
WO2019048930A3 (en) 2019-04-18
US20220031776A1 (en) 2022-02-03
EP3678639B1 (en) 2022-02-16
EP3678639A2 (en) 2020-07-15

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Application publication date: 20201020