JP2020533408A - 炎症性腸疾患を制御するためのバクテリオファージ - Google Patents

炎症性腸疾患を制御するためのバクテリオファージ Download PDF

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Publication number
JP2020533408A
JP2020533408A JP2020535321A JP2020535321A JP2020533408A JP 2020533408 A JP2020533408 A JP 2020533408A JP 2020535321 A JP2020535321 A JP 2020535321A JP 2020535321 A JP2020535321 A JP 2020535321A JP 2020533408 A JP2020533408 A JP 2020533408A
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Japan
Prior art keywords
kp2m
kp2w
kp3w
bacteriophage
bacteriophages
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Withdrawn
Application number
JP2020535321A
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English (en)
Japanese (ja)
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JP2020533408A5 (enExample
Inventor
賢也 本田
賢也 本田
幸二 新
幸二 新
聖子 成島
聖子 成島
エリナブ エラン
エリナブ エラン
ソレック ロテム
ソレック ロテム
カブラ エフラット
カブラ エフラット
ベン ダビッド ハヴァ
ベン ダビッド ハヴァ
ウェインストック エヤル
ウェインストック エヤル
ポロック サラ
ポロック サラ
ムティウヒン ユリア
ムティウヒン ユリア
ザック ナオミ
ザック ナオミ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Biomx Ltd
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Yeda Research and Development Co Ltd
Biomx Ltd
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Application filed by Yeda Research and Development Co Ltd, Biomx Ltd filed Critical Yeda Research and Development Co Ltd
Publication of JP2020533408A publication Critical patent/JP2020533408A/ja
Publication of JP2020533408A5 publication Critical patent/JP2020533408A5/ja
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2020535321A 2017-09-08 2018-09-07 炎症性腸疾患を制御するためのバクテリオファージ Withdrawn JP2020533408A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762555790P 2017-09-08 2017-09-08
US62/555,790 2017-09-08
PCT/IB2018/001128 WO2019048930A2 (en) 2017-09-08 2018-09-07 BACTERIOPHAGE OF MODULATION OF INFLAMMATORY INTESTINAL DISEASE

Publications (2)

Publication Number Publication Date
JP2020533408A true JP2020533408A (ja) 2020-11-19
JP2020533408A5 JP2020533408A5 (enExample) 2021-10-07

Family

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Family Applications (1)

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JP2020535321A Withdrawn JP2020533408A (ja) 2017-09-08 2018-09-07 炎症性腸疾患を制御するためのバクテリオファージ

Country Status (7)

Country Link
US (1) US20220031776A1 (enExample)
EP (2) EP3678639B1 (enExample)
JP (1) JP2020533408A (enExample)
CN (1) CN111801107A (enExample)
AU (1) AU2018330848A1 (enExample)
CA (1) CA3074406A1 (enExample)
WO (1) WO2019048930A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112469426B (zh) * 2018-05-23 2025-07-11 布莱阿姆青年大学 噬菌体组合物和试剂盒及相关方法
US11986502B2 (en) 2018-05-23 2024-05-21 Optium, LLC Bacteriophage compositions and kits and related methods
CA3131316A1 (en) 2019-03-07 2020-09-10 Keio University Bacteriophage for modulating inflammatory bowel disease
US20240075084A1 (en) * 2021-01-21 2024-03-07 Biomx Ltd. Klebsiella bacteriophage and uses thereof
US20250281553A1 (en) * 2021-04-22 2025-09-11 Ferring B.V. Bacteriophage therapy against adherent-invasive escherichia coli
CN115558650B (zh) * 2022-10-09 2023-05-30 优宜邦生物科技(上海)有限公司 一种宽宿主谱变栖克雷伯氏菌噬菌体及其应用和制剂
CN118318913A (zh) * 2024-05-09 2024-07-12 江苏省农业科学院 一种含有噬菌体的新型饲料添加剂及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
EP2799063A1 (en) * 2013-04-30 2014-11-05 Ferring B.V. Bacteriophage therapy
CN106754745B (zh) * 2016-11-29 2020-07-14 江苏省农业科学院 一种肺炎克雷伯氏菌噬菌体及其应用

Also Published As

Publication number Publication date
EP3678639B1 (en) 2022-02-16
CA3074406A1 (en) 2019-03-14
AU2018330848A1 (en) 2020-03-12
EP4032526A1 (en) 2022-07-27
WO2019048930A2 (en) 2019-03-14
US20220031776A1 (en) 2022-02-03
CN111801107A (zh) 2020-10-20
EP3678639A2 (en) 2020-07-15
WO2019048930A3 (en) 2019-04-18

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