CN111773359A - 一种用于治疗胃炎的胶囊 - Google Patents

一种用于治疗胃炎的胶囊 Download PDF

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CN111773359A
CN111773359A CN201910292480.6A CN201910292480A CN111773359A CN 111773359 A CN111773359 A CN 111773359A CN 201910292480 A CN201910292480 A CN 201910292480A CN 111773359 A CN111773359 A CN 111773359A
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Abstract

发明一种用于治疗胃炎的胶囊,用中医中药制成胶囊或丸剂治疗由幽门螺杆菌感染和其他病因引起的慢性浅表性胃炎。用中草药制成中成药(包括胶囊、丸剂)进行口服药物治疗。根据西医理论,慢性浅表性胃炎按溃疡来处理的原理,所以该方亦可用来治疗胃溃疡病。采用补中益气健脾、理气和胃,清热解毒、抗菌消炎、凉血、活血化瘀于一体的药物抑杀HP生长,促进炎症消退和溃疡愈合。

Description

一种用于治疗胃炎的胶囊
技术领域:
本技术涉及用中医中药制成胶囊或丸剂治疗由幽门螺杆菌感染或其他病因引起的慢性浅表性胃炎。
背景技术:
根据观察,由于慢性胃炎病患者比较多,而且体力劳动者占大多数,病史较长,患者胃粘膜活标本HP 检出率达60-80%。幽门螺杆菌(HP)感染已成为慢性胃炎、消化性溃疡的主要病因,其感染可使细胞增殖,发生肠上皮化生,使胃癌的发生率增高。现有的治疗方法西医采用铋剂、H2受体阻滞剂或质子泵抑制剂加抗生素三联疗法,也有一定的HP根除效果。但西药副作用发生率高,停药后复发率高,长期服用抗生素,易引起肠道菌群紊乱,HP产生耐药性也在增长。另外,长期服用西药,根据中医的理论,会损伤脾胃之气阴。中医药治疗HP相关胃病,其疗效综合全面,稳定可靠,副作用少,很有发展前景。
发明内容:
为了解决目前西医治疗慢性浅表性胃炎副作用多,容易复发,HP难以根除等弊端,本技术根据中医的理论,采用中草药组方,治疗HP感染或其他病因引起的慢性浅表性胃炎。
慢性浅表性胃炎的临床表现为以反复或持续性上腹不适、饱胀、钝痛、烧灼痛、嘈杂、嗳气为临床表现。西医对该病的病因认识主要为幽门螺杆菌感染、物理化学因素、遗传因素、饮食不规律、营养因素等。胃镜检查及胃粘膜标本检出幽门螺杆菌(HP),提示慢性活动炎症征象,包括充血、红白相间、水肿、糜烂等。根据中医学的理论,该病属于“痞证”的范畴,其病机为寒热错杂等,其症型包括虚寒证、气滞症、湿热证等。由于慢性胃炎病史长,往往兼有气滞或血瘀。根据西医的理论,慢性胃炎按照溃疡来处理的原理,该胶囊主要用于治疗慢性浅表性胃炎、胃溃疡。其组方如下:
黄芪15g、党参9g、生地10g、白术10g、当归10g、茯苓12g、陈皮10g、木香6g、佛手12g、连翘 12g、白花蛇舌草9g、蒲公英30g、黄连6g、栀子6g、金不换10g、浙贝母12g、丹参12g、红花6g、海螵蛸15g、瓦楞子10g、半夏10g、枳壳10g、延胡索9g、干姜3g、甘草6g
组方中各药物之间的关系:黄芪、党参、白术、当归、生地、陈皮、茯苓补中益气健脾,加速溃疡愈合,同时缓黄连、栀子、浙贝母等苦寒药物折胃之弊;陈皮、木香、佛手理气和胃清除暧气;连翘、白花蛇舌草、蒲公英、黄连、栀子清热解毒、凉血,具有广谱抗菌消炎及抑制病毒的作用,抑杀HP生长,清除胃黏膜水肿的作用;金不换杀菌护膜,增强清热解毒,破疡生新,消肿止痛,抑制胃酸和胃蛋白酶分泌,有效抑制幽门螺杆菌生长和繁殖,改善胃黏膜的血液循环,促进溃疡病灶愈合,对虚寒证、气滞症、湿热证有效;浙贝母除热散结;丹参、红花活血化瘀,对胃体部黏膜充血,水肿有显著的消退作用,这类药物由于调节血液循环,促进新陈代谢,增强免疫功能,从而消除病毒和炎性产物,改善胃体营养,促进炎症消退和溃疡愈合;海螵蛸、瓦楞子消除烧心、吐酸、嘈杂;半夏辛开散结,苦降和胃;枳壳、延胡索理气宽中,行滞消胀止痛;干姜温中散寒;甘草补中缓急止痛,调和诸药;同时,蒲公英、金不换、生地、半夏对炎症区胃黏膜伴糜烂有促进修复和愈合作用。诸药合用,辛开苦降,寒热并用,相符慢性浅表胃炎寒热错杂之病机。
注意:上消化道出血、痔疮出血、妇女经期禁用。
治疗胃炎中草药配方供制药厂加工制成胶囊、丸剂。
具体实施方式
梁某某,男,55岁,1990年9月开始出现胃脘部隐痛、胀、暧气、嘈杂等症状。曾多次行胃镜查示:慢性浅表性胃炎,幽门螺杆菌感染,曾服用多种中西药治疗,症状时轻时重,碰到冬季气候骤冷,疼痛持续加重。该串者直到2015年11月服用治疗胃炎的中药汤剂20剂后,诸症消失。

Claims (3)

1.一种用于治疗胃炎的胶囊,用中医中药组方治疗由幽门螺杆菌感染和其他病因引起的慢性浅表性胃炎。采用补中益气健脾、理气和胃、清热解毒、抗菌消炎、凉血、活血化瘀于一体的药物抑杀HP生长,促进炎症消退和溃疡愈合。
2.一种用于治疗胃炎的胶囊,其与西医的治疗原则共有的必要技术牲征为:①根除HP,适用HP相关性胃炎;②抑酸或抗酸治疗,适用于胃粘膜糜烂或以烧心、泛酸、上腹饥饿痛等症状;③增强胃粘膜防御功能。适用于胃粘膜糜烂者。
3.一种用于治疗胃炎的胶囊,配方其特征是补中益气健脾、理气和胃、清热解毒、抗菌消炎、凉血、活血化瘀。
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