CN111743037A - Animal welfare anti-functional additive - Google Patents
Animal welfare anti-functional additive Download PDFInfo
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- CN111743037A CN111743037A CN202010669142.2A CN202010669142A CN111743037A CN 111743037 A CN111743037 A CN 111743037A CN 202010669142 A CN202010669142 A CN 202010669142A CN 111743037 A CN111743037 A CN 111743037A
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- 235000013406 prebiotics Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 229940069949 propolis Drugs 0.000 description 1
- 229940116540 protein supplement Drugs 0.000 description 1
- 235000005974 protein supplement Nutrition 0.000 description 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- UCRLQOPRDMGYOA-DFTDUNEMSA-L zinc;(4r)-4-[[(2s)-2-[[(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2s,3s)-1-[[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carbox Chemical compound [Zn+2].C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2NC=NC=2)C(=O)N[C@H](CC([O-])=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 UCRLQOPRDMGYOA-DFTDUNEMSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/125—Casei
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
Abstract
The invention belongs to the technical field of feed additives, and particularly relates to an animal welfare resisting functional additive. The animal welfare agent anti-functional additive contains 500 g of stevioside, 20-100 g of lucid ganoderma extract, 20-100 g of lycium barbarum polysaccharide, 80-200 g of liquorice extract, 80-200 g of isatis root extract, 250g of composite microbial agent and the balance of water-soluble carrier per kilogram of the additive; wherein each gram of the composite microbial inoculum contains 50-100 hundred million of enterococcus faecalis, 3-15 million of clostridium butyricum, 3-15 million of lactobacillus plantarum and lactobacillus casei composite bacteria, 30-80 million of bacillus subtilis and 30-80 million of bacillus licheniformis. The additive provided by the invention can promote the conversion rate of lean meat of the feed, improve the quality of animal meat, improve the growth rate of animals and create more economic benefits for animal feeding enterprises.
Description
Technical Field
The invention belongs to the technical field of feed additives, and particularly relates to an animal welfare resisting functional additive.
Background
In modern large-scale livestock and poultry breeding production, in order to pursue the rapid growth, better bacteriostasis and disease resistance of livestock and poultry, antibiotics, hormones, chemical synthetic drugs and the like are added into feed, but the long-term use of the substances causes the problems of drug resistance of pathogenic microorganisms, drug residue of animal products, environmental pollution and the like, so the research and the use of novel drug feed additives are more and more regarded. For example, in the seventies of the twentieth century, the european union began to suspend approval of several important antibiotics to be added to animal feed at sub-therapeutic dose concentrations. In 1987, it was first proposed in sweden to disable growth-promoting antibiotics in the feed. Subsequently, countries with antibiotics banned are danish, germany, finland, and those banned with avomycin, tylosin, spiramycin and virginiamycin. The eu committee banned the use of avomycin in animal feed in 1997, and the eu minister committee banned the use of tylosin, spiramycin, bacitracin zinc and virginiamycin in animal feed in the end of 1998.
In addition, with the pursuit of healthy life, the demand for lean meat is increasing. However, in animal production, methods for increasing lean meat percentage and meat quality of animals still remain to use some hormone drugs, such as sex hormones and beta-agonists. Because of improper use of the substances, residues can be generated in animals, and the substances cause harm to the health of human beings. Therefore, it is an urgent need to provide a safe and effective additive to improve the conversion rate of lean meat, improve the quality of animal meat and promote the growth of animals.
Chinese patent application CN201611194917.5 discloses a feed additive for improving the conversion rate of goose feed, which is prepared from the following materials in parts by weight: 10-20 parts of liquorice, 15-25 parts of longan leaves, 5-10 parts of red dates, 3-8 parts of chitosan oligosaccharide, 1-2 parts of bifidobacteria, 1-2 parts of lactic acid bacteria, 20-30 parts of bean curd residues, 10-20 parts of figs, 5-8 parts of pomegranate peels, 3-8 parts of pumpkin seeds, 4-6 parts of sunflower seeds, 5-8 parts of hawthorn, 3-6 parts of dried orange peels, 5-10 parts of garlic, 5-10 parts of lemons, 2-5 parts of porphyra, 5-10 parts of malt and 10-20 parts of tea seeds; the feed additive contains various vitamins, trace elements, beneficial bacteria and other substances, can promote digestion of the geese, improve the feed conversion rate, promote growth of the geese, shorten the feeding time, prevent fat deposition, improve the lean meat percentage of the geese and improve the meat quality.
Chinese patent application CN201611233233.1 discloses a duck feed additive, which is prepared from the following materials in parts by weight: 10-20 parts of pork liver, 3-8 parts of liquorice, 5-10 parts of garlic, 5-8 parts of seaweed, 2-3 parts of propolis, 10-20 parts of earthworm, 1-2 parts of beer yeast, 5-10 parts of malt, 10-20 parts of pumpkin seed, 3-5 parts of honeysuckle, 1-2 parts of salt, 5-8 parts of green tea, 0.5-1 part of vitamin complex, 0.5-1 part of chitosan, 3-8 parts of ginger, 0.2-0.5 part of protease and 2-8 parts of fish oil; the pig liver and the earthworms added in the feed additive contain rich protein, can provide additional protein supplement for ducks, promote the daily weight gain of the ducks, and meanwhile, the earthworms have fishy smell and have a food calling effect to promote the ducks to eat; the invention also adds protease which can promote the decomposition of protein, promote the absorption of duck to protein, promote the growth of duck meat and improve the protein conversion rate of duck to feed.
However, the above additives have limited conversion rate of lean meat and immune recovery effect on animals due to addition of a large amount of food materials as raw materials.
Disclosure of Invention
In order to overcome the problems in the prior art, the invention aims to provide the animal welfare anti-functional additive which has high conversion rate of lean meat and can improve the immunity of animals.
In order to achieve the above purpose, the invention provides the following technical scheme:
an animal welfare agent anti-functional additive, wherein each kilogram of the additive contains 500 g of stevioside, 20-100 g of lucid ganoderma extract, 20-100 g of lycium barbarum polysaccharide, 80-200 g of licorice extract, 80-200 g of isatis root extract, 250g of composite microbial agent and the balance of water-soluble carrier; wherein each gram of the composite microbial inoculum contains 50-100 hundred million of enterococcus faecalis, 3-15 million of clostridium butyricum, 3-15 million of lactobacillus plantarum and lactobacillus casei composite bacteria, 30-80 million of bacillus subtilis and 30-80 million of bacillus licheniformis.
Preferably, the weight ratio of the stevioside to the ganoderma lucidum extract to the lycium barbarum polysaccharide is 5: 1: 1.
preferably, each kilogram of the additive contains 250g of stevioside, 50g of ganoderma lucidum extract and 50g of lycium barbarum polysaccharide.
Preferably, the concentration ratio of enterococcus faecalis, clostridium butyricum, lactobacillus plantarum, lactobacillus casei compound bacteria, bacillus subtilis and bacillus licheniformis is 8: 1: 1: 1: 5: 5.
preferably, the concentration of enterococcus faecalis, clostridium butyricum, lactobacillus plantarum, lactobacillus casei complex bacteria, bacillus subtilis and bacillus licheniformis is 80 hundred million, 10 hundred million of clostridium butyricum, lactobacillus plantarum, 10 hundred million of lactobacillus casei complex bacteria, 50 hundred million of bacillus subtilis and 50 hundred million of bacillus licheniformis in each gram of the complex microbial inoculum.
Preferably, each kilogram of additive contains 250g of stevioside, 50g of ganoderma lucidum extract, 50g of lycium barbarum polysaccharide, 80 hundred million of enterococcus faecalis, 10 hundred million of clostridium butyricum, 10 hundred million of lactobacillus plantarum and lactobacillus casei compound bacteria, 50 hundred million of bacillus subtilis, 50 hundred million of bacillus licheniformis, 100g of liquiritin, 100g of isatis root extract and the balance of water-soluble carrier.
Preferably, the water soluble carrier is anhydrous glucose.
The invention also provides a method for preparing the animal welfare anti-functional additive, which comprises the following steps:
mixing stevioside, lycium barbarum polysaccharide, a ganoderma lucidum extract, a liquorice extract, an isatis root extract and a composite microbial agent to obtain the bactericide.
Preferably, the stevioside, the lycium barbarum polysaccharide, the ganoderma lucidum extract, the licorice extract and the isatis root extract can be prepared by the following methods: soaking the decoction pieces in 8-10 times of water, heating to slightly boiling state, treating for 1-3 hr, discharging the liquid, repeatedly extracting the residue for 2-3 times, mixing the medicinal liquids, standing for precipitation, filtering, concentrating the filtrate under reduced pressure, drying, collecting powder, inspecting, and packaging.
Taking the preparation method of the ganoderma lucidum extract as an example, the method comprises the following steps:
weighing Ganoderma decoction pieces, adding 8-10 times of water, heating to 40-50 deg.C, soaking for 1-3 hr, heating to 90-100 deg.C, treating for 1-3 hr, discharging the material liquid, adding 8-10 times of water into the residue, heating to 90-100 deg.C, treating for 1-3 hr, discharging the material liquid, adding 6-8 times of water into the residue, treating for 0.5-1 hr at 90-100 deg.C, discharging the material liquid, and discarding the residue. Mixing the three medicinal liquids, standing for 2-3h, filtering with plate frame, concentrating the filtrate under reduced pressure to specific gravity of 1.10-1.20 at 60 deg.C, spray drying, collecting powder, inspecting, and packaging.
As a preferred embodiment, the preparation method of the ganoderma lucidum extract comprises the following steps:
weighing Ganoderma decoction pieces, adding 10 times of water, heating to 45 deg.C, soaking for 1 hr, heating to 98 deg.C, treating for 2.0 hr, discharging the liquid, adding 10 times of water into the residue, heating to 98 deg.C, treating for 2.0 hr, discharging the liquid, adding 8 times of water into the residue, heating to 98 deg.C, treating for 1.0 hr, discharging the liquid, and discarding the residue. Mixing the three medicinal liquids, standing for 3 hr, filtering with plate frame, concentrating the filtrate under reduced pressure until the specific gravity of the medicinal liquid is 1.12-1.14 (measured at 60 deg.C), spray drying, collecting powder, inspecting, and packaging.
In the invention, the main components of the ganoderma lucidum extract are ganoderma lucidum polysaccharide and the like. It has effects in invigorating spleen, replenishing qi, invigorating spleen, and nourishing lung; the traditional Chinese medicine composition is mainly used for treating weakness of spleen and stomach of livestock and poultry, poor appetite and diarrhea, cough and asthma due to lung deficiency, tiredness and weakness, qi deficiency and prolapse and the like. Modern pharmacology proves that the ganoderma lucidum has the effects of enhancing the inhibition of a central nervous system, adjusting the function of vegetative nerves, improving coronary flow, enhancing myocardial contraction force, improving microcirculation, reducing blood pressure and blood fat, improving the immunity of organisms, protecting the liver and the kidney and the like.
Steviol glycosides, the sweet component of stevia called steviol glycosides, have a common steviol skeleton, and the number of glucose units and their arrangement on the steviol skeleton vary, so that each steviol glycoside has a unique taste and sweetness. Wherein, Stevioside and Reb A are most common, and the total content of the Stevioside and Reb A accounts for 14-18% of the total components of stevia rebaudiana. The steviol glycosides pharmacological activity is as follows:
1) anti-diabetic activity; 2) lowering blood pressure and reducing blood lipid; 3) preventing tumors; 4) regulating blood lipid; 5) inhibiting pathogenic bacteria; 6) can promote mineral absorption.
The wolfberry polysaccharide is a natural macromolecular water-soluble polysaccharide extracted from wolfberry. The research shows that the medicine has the pharmacological activities of regulating immunity, reducing blood sugar, reducing blood fat, delaying senility, resisting fatigue and the like.
The main active component of the licorice extract, namely the glycyrrhiza polysaccharide, has the seasoning effect on one hand, and can play the roles of inhibiting the growth of tumors, regulating the immune function of organisms, improving the oxidation resistance and the like on the other hand.
In the invention, the monarch, minister, assistant and guide compatibility relations among stevioside, lucid ganoderma extracts, medlar polysaccharide, liquorice extracts and isatis root extracts are utilized, wherein the stevioside is a monarch drug and is mainly used for promoting the secretion of saliva or body fluid, tonifying spleen and improving physical strength; the ganoderma lucidum extract and the lycium barbarum polysaccharide are used as ministerial drugs, the ganoderma lucidum polysaccharide improves the immunity of the organism, generates interferon, and the lycium barbarum polysaccharide nourishes kidney, moistens lung, tonifies liver and improves eyesight; the licorice extract and the isatis root extract are used as guiding drugs together, wherein the licorice protects the liver and harmonizes the liver and the stomach, the licorice and the isatis root extract play a role in nourishing and health-care functions of internal organs of animals together and can improve the spirit of the animals, and the isatis root is used for clearing heat and removing toxicity. The polysaccharide in the formula provided by the invention is a better prebiotic, and is assisted with promotion of propagation, planting and proliferation of beneficial bacteria in intestinal tracts and supplementation of beneficial bacteria, so that the intestinal tracts are protected, nutrient absorption is promoted, and the natural sweet taste of the extract enables the animal to be pleasant and good, so that the animal can generate the best immunity in the best healthy state.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention provides an animal feed additive capable of replacing antibiotics, which can promote the conversion rate of lean meat of feed, improve the quality of animal meat and improve the growth rate of animals. Meanwhile, the disease resistance of animals can be improved, the morbidity probability of the animals can be reduced, the survival rate of the animals can be improved, and the economic benefit of animal feeding enterprises can be improved.
2. The animal welfare substituting anti-functional additive provided by the invention is used for animal slaughtering health care, can improve the health of animal organs and the toxin expelling capability of animal organisms, can be used for health care type feeding before animal slaughtering, promotes animals to discharge toxins such as antibiotics and the like, and enables the meat quality of animals to be recovered to be normal. The feedback of the feeding user shows that the medicine residues in the animal bodies can be effectively metabolized completely after the feeding with the functional additive provided by the invention.
3. The additive provided by the invention pays attention to the compatibility relationship among all the components, and can be quickly recovered in a short time after a period of time for animal organisms damaged by antibiotics, so that the immunity of the animal organisms is improved, and the health of the animal organisms is enhanced.
Detailed Description
The method of the present invention is described below with reference to specific examples to make it easier to understand and understand the technical solution of the present invention, but the present invention is not limited thereto. The experimental methods described in the following examples are all conventional methods unless otherwise specified; the reagents and materials are commercially available, unless otherwise specified.
Example 1
An animal welfare anti-functional additive, the formula is: each kilogram of additive contains 250g of stevioside, 50g of lucid ganoderma extract, 50g of lycium barbarum polysaccharide, 100g of liquorice extract, 100g of isatis root extract and 250g of composite microbial inoculum, wherein each gram of composite microbial inoculum contains 80 hundred million of enterococcus faecalis, 10 hundred million of clostridium butyricum, 3 hundred million of lactobacillus plantarum, 7 hundred million of lactobacillus casei, 50 hundred million of bacillus subtilis and 50 hundred million of bacillus licheniformis, and the balance is anhydrous glucose as a water-soluble carrier.
The preparation method comprises the following steps:
s1, preparing the ganoderma lucidum extract: weighing Ganoderma decoction pieces, adding 10 times of water, heating to 45 deg.C, soaking for 1 hr, heating to 98 deg.C, treating for 2.0 hr, discharging the liquid, adding 10 times of water into the residue, heating to 98 deg.C, treating for 2.0 hr, discharging the liquid, adding 8 times of water into the residue, heating to 98 deg.C, treating for 1.0 hr, discharging the liquid, and discarding the residue. Mixing the three medicinal liquids, standing for 3 hr, filtering with plate frame, concentrating the filtrate under reduced pressure until the specific gravity of the medicinal liquid is 1.12-1.14 (measured at 60 deg.C), spray drying, collecting powder, inspecting, and packaging.
S2, preparation of other plant extracts: the preparation method of the reference ganoderma lucidum extract comprises the following operation steps:
weighing medicinal decoction pieces, adding 8-10 times of water, heating to 40-50 deg.C, soaking for 1-3 hr, heating to 90-100 deg.C, treating for 1-3 hr, discharging the liquid, adding 8-10 times of water into the residue, heating to 90-100 deg.C, treating for 1-3 hr, discharging the liquid, adding 6-8 times of water into the residue, treating for 0.5-1 hr at 90-100 deg.C, discharging the liquid, and discarding the residue. Mixing the three medicinal liquids, standing for 2-3h, filtering with plate frame, concentrating the filtrate under reduced pressure to specific gravity of 1.10-1.20 at 60 deg.C, spray drying, collecting powder, inspecting, and packaging.
S3, mixing the plant extracts, the complex microbial inoculum and a water-soluble carrier.
Example 2
An animal welfare anti-functional additive which is different from that of example 1 in that the formula is as follows: each kilogram of additive contains 150 g of stevioside, 100g of ganoderma lucidum extract, 100g of lycium barbarum polysaccharide, 100g of licorice extract, 100g of isatis root extract and 250g of composite microbial inoculum, wherein each gram of composite microbial inoculum contains 80 hundred million of enterococcus faecalis, 10 hundred million of clostridium butyricum, 3 hundred million of lactobacillus plantarum, 7 hundred million of lactobacillus casei, 50 hundred million of bacillus subtilis and 50 hundred million of bacillus licheniformis, and the balance is anhydrous glucose as a water-soluble carrier.
Example 3
An animal welfare anti-functional additive, which is different from example 1 in that,
each gram of the composite microbial inoculum contains 100 hundred million of enterococcus faecalis, 10 hundred million of clostridium butyricum, 3 hundred million of lactobacillus plantarum, 7 hundred million of lactobacillus casei, 40 hundred million of bacillus subtilis and 40 hundred million of bacillus licheniformis, wherein the balance is water-soluble carrier anhydrous glucose.
Comparative example 1
An animal welfare anti-functional additive which, compared to example 1, omits 250 grams of steviol glycoside in the formulation.
Comparative example 2
An animal welfare anti-functional additive, which is compared with example 1, wherein 100g of isatis root extract in the formula is omitted.
Experimental example 1
The experimental example discusses the influence of the feed additive provided by the invention on the growth performance of animals
Experimental methods
4800 36-day-old Ross 308 healthy broilers from a chicken factory were selected and randomly divided into 4 barns, 1200 broilers per barn, 1 week before slaughter, the experimental group used the feed containing the additives provided in the examples each day in the amount calculated by feed intake (1kg/2000kg feed/chicken), the control group used the feed containing no additives, 2 drinking water times in the morning and afternoon, 6 days continuously, the other feeding conditions in each barn were identical, slaughter was performed for 42 days, and the test results are shown in Table 1 below.
Wherein the initial weight, the final weight, the daily average feed intake, the daily average weight gain and the like are average values.
TABLE 1
In addition to the change in the feed-meat ratio, diarrhea rate and death and culling rate described in table 1, the odor of the chicken coop before and after the experiment also changed significantly. Before the experiment is started, all chicken houses have serious ammonia smell, people can tear eyes when entering the chicken houses, and the chicken manure is observed to find that the excrement is loose and is inconvenient to clean; at the end of the experiment, the ammonia smell disappears, and the excrement is fine and smooth without the phenomenon of diarrhea. The death and culling rate is obviously reduced, the feed conversion ratio is better than that of a comparison group, and the economic benefit is obvious.
Experimental example 2
The effect of the animal welfare anti-functional additive on the metabolism of drug residues in vivo
Selecting 6 thousands of meat ducks, feeding the meat ducks in 6 closed sheds, randomly selecting the meat ducks from meat duck farms, and carrying out two times of detection in the drug test before slaughtering, wherein the two times of detection are unqualified due to the overproof antibiotics. After the additives provided by the examples and the comparative examples of the invention are respectively added into the meat ducks in the shed and used for 7 days, the meat ducks in the sheds are subjected to the drug tests again, and the drug test results before and after the meat ducks in the examples are used with the additives are shown in the following table 2. Wherein, the using method of the medicine comprises the following steps: drinking water, and using dosage: average 200 g/piece/day. The detection method comprises the following steps: and (3) taking a duck breast muscle sample to be detected, and detecting by adopting a mass spectrometer.
TABLE 2 results of enrofloxacin testing before and after drug administration
In addition, animals were similarly investigated for metabolism of other classes of antibiotics after use of the functional additive as shown in tables 3-4 below.
TABLE 3 detection results of olaquindox metabolites before and after drug administration
TABLE 4 sulfonamide assay results before and after drug administration
Customer usage feedback is as follows:
1. 8600 meat ducks are bred in a single Dacron farm with Qufu, and bred in two sheds. When the duck is bred for about 30 days, the duck gets the viral disease, and the additive provided in the embodiment 1 is added for matching treatment while the duck is bred normally, wherein the additive is used for 7 days totally, and the dosage of the additive is 200 g/duck/day.
Customer evaluation: the meat duck is easy to treat after the disease occurs, can recover quickly, and has strong immunity and high slaughtering rate.
2. Feeding 3 ten thousand meat ducks in a Yiyi Pingyi Feng plain farm, and detecting by drug inspection under the condition that glucose and vitamin C are used in the later period, wherein mequindox exceeds the standard; then 200 g/only/day of the additive provided by the embodiment 1 is added, the mixture is used for two days, and the medicine inspection reaches the standard.
3. 37075and 3.8 thousands of laying hens in the town of city.
Test shed: 3/4 No. C
Contrast canopy: 1/2 No. C
The using method comprises the following steps: the drinking water service time is as follows: 8 days
The number of the laying hens which are used is as follows: 1.9 thousands of
Comparing the number of laying hens: 1.9 thousands of
The additive usage amounts provided in example 2: 200 g/piece/day.
The test effect is as follows:
after the test shed is continuously used for 6 days, the excrement of chicken flocks is obviously improved, the concentration of fishy smell in the shed is reduced, and the large flocks are in a non-diluted state; after 8 days of continuous administration, the appearance of large group of feathers is spiritual and the eyes are bright.
The eggs in the two sheds are compared, and the eggs in the experimental shed are fragrant, have no fishy smell and have high yolk concentration.
4. The experimental summary of the stocked layer chicken breeding factory in northeast Yangji state: laying hens (white eggs and pink eggs) are fed in the shed, the day age is 510 days, 7000 eggs are fed, the feed is mixed with the raw materials of the additive provided by the embodiment 1 at a ratio of 100 g/egg/day, and compared with the feed in the shed, experimental data show that when the additive provided by the embodiment 1 is used for 4 days, the feed of an experimental group is reduced to some extent, and when the feed is used for 7 days, the eggs of the experimental group are stable, the eggs of a comparison group are reduced obviously, and the casualties of the comparison group are large. Experiments prove that the additive provided by the embodiment 1 can protect liver and kidney, improve immunity, ensure that the chicken is healthier, can be used for a short time, improve the conversion rate of feed, reduce the feed amount, be used for a long time, prolong the egg laying peak value and reduce the feed-egg ratio.
5. The Xuzhou Peixian Guokouvillage meat goose farms are used for breeding more than 5000 meat geese in 1 shed and 2 sheds, and each shed is 2500 meat geese, wherein 100g of the additive provided in the embodiment 1 is added into the shed 1 at the age of 55 days in day, the additive is continuously used for 8 days, and the breeding period is 70 days. The comparison of weighing data before shed-making shows that the average weight of the shed 1 is 1 or two times higher than that of the shed 2, and 1 more shed is earned than 1 more shed for each shed 2 according to market price. The raiser reflects that the feather pecking phenomenon of the shed 1 is obviously reduced compared with that of the shed 2, the feathers are smooth and bright, and another economic benefit is brought to the raiser.
Finally, it should be noted that the above-mentioned contents are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, and that the simple modifications or equivalent substitutions of the technical solutions of the present invention by those of ordinary skill in the art can be made without departing from the spirit and scope of the technical solutions of the present invention.
Claims (9)
1. An animal welfare agent anti-functional additive is characterized in that each kilogram of the additive contains 500 g of stevioside, 20-100 g of lucid ganoderma extract, 20-100 g of lycium barbarum polysaccharide, 80-200 g of liquorice extract, 80-200 g of isatis root extract, 250g of composite microbial inoculum and the balance of water-soluble carrier; wherein each gram of the composite microbial inoculum contains 50-100 hundred million of enterococcus faecalis, 3-15 million of clostridium butyricum, 3-15 million of lactobacillus plantarum and lactobacillus casei composite bacteria, 30-80 million of bacillus subtilis and 30-80 million of bacillus licheniformis.
2. The animal welfare anti-functional additive of claim 1, wherein the weight ratio of steviol glycosides, ganoderma lucidum extract, lycium barbarum polysaccharide is 5: 1: 1.
3. the animal welfare anti-functional additive according to claim 1, wherein each kilogram of the additive comprises 250 grams of stevioside, 50 grams of ganoderma lucidum extract and 50 grams of lycium barbarum polysaccharide.
4. The animal welfare anti-functional additive according to claim 1, wherein the concentration ratio of enterococcus faecalis, clostridium butyricum, lactobacillus plantarum, lactobacillus casei complex, bacillus subtilis, bacillus licheniformis is 8: 1: 1: 1: 5: 5.
5. the animal welfare agent functional additive according to claim 1, wherein the concentration of enterococcus faecalis, clostridium butyricum, lactobacillus plantarum, lactobacillus casei, bacillus subtilis, and bacillus licheniformis is 80 hundred million, the concentration of clostridium butyricum is 10 hundred million, the concentration of lactobacillus plantarum, lactobacillus casei complex is 10 hundred million, the concentration of bacillus subtilis is 50 hundred million, and the concentration of bacillus licheniformis is 50 hundred million.
6. The animal welfare agent functional additive according to claim 1, wherein each kilogram of the additive comprises 250g of stevioside, 50g of ganoderma lucidum extract, 50g of lycium barbarum polysaccharide, 80 hundred million of enterococcus faecalis, 10 hundred million of clostridium butyricum, 10 hundred million of lactobacillus plantarum and lactobacillus casei compound bacteria, 50 hundred million of bacillus subtilis, 50 hundred million of bacillus licheniformis, 100g of liquiritin, 100g of isatis root extract and the balance of anhydrous glucose as a water-soluble carrier.
7. The animal welfare anti-functional additive according to any one of claims 1 to 6, characterised in that the water soluble carrier is anhydrous glucose.
8. A method of preparing the animal welfare anti-functional additive of any one of claims 1 to 7, comprising the steps of:
mixing stevioside, lycium barbarum polysaccharide, lucid ganoderma extract, liquorice extract, isatis root extract and the composite microbial agent to obtain the composition.
9. The method according to claim 8, wherein the ganoderma lucidum extract is prepared by a method comprising the steps of:
weighing Ganoderma decoction pieces, adding 8-10 times of water, heating to 40-50 deg.C, soaking for 1-3 hr, heating to 90-100 deg.C, treating for 1-3 hr, discharging the material liquid, adding 8-10 times of water into the residue, heating to 90-100 deg.C, treating for 1-3 hr, discharging the material liquid, adding 6-8 times of water into the residue, treating for 0.5-1 hr at 90-100 deg.C, discharging the material liquid, and discarding the residue; mixing the three medicinal liquids, standing for 2-3h, filtering with plate frame, concentrating the filtrate under reduced pressure to specific gravity of 1.11-1.18 at 60 deg.C, spray drying, collecting powder, inspecting, and packaging.
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| CN114617202A (en) * | 2022-03-29 | 2022-06-14 | 江苏三仪生物工程有限公司 | Compound microecological preparation for improving disease resistance and production performance of ducks as well as preparation method and application of compound microecological preparation |
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