CN111690307B - Spraying type invisible breathable coating film and gloves with waterproof, antibacterial and antiviral functions, base material and glove preparation method and cleaning method - Google Patents
Spraying type invisible breathable coating film and gloves with waterproof, antibacterial and antiviral functions, base material and glove preparation method and cleaning method Download PDFInfo
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
- C09D151/08—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
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- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
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Abstract
The invention provides a spray-type invisible breathable coating film with waterproof, antibacterial and antiviral functions, a glove, a base material and a preparation method and a removal method of the glove, and aims at solving the key problem of a contact transmission path which is difficult to solve in the infectious disease prevention and control process. The glove has good flexibility, can effectively resist bacteria and viruses, and has the advantages of simple operation, good air permeability, strong flexibility and the like. Particularly in the aspect of preventing and treating contact transmission diseases, the invention relates to a portable spraying type antibacterial antiviral breathable invisible glove and technology. The invisible gloves designed by the invention are suitable for public places such as hospitals, nursing, catering, buses, households, travels and the like to prevent pathogen transmission caused by direct contact or indirect contact, can effectively cut off pollution source transmission ways, and improve the health level of people.
Description
Technical Field
The invention relates to the technical field of waterproof antibacterial antiviral medical protection, in particular to a spraying type invisible breathable coating film and gloves with waterproof antibacterial antiviral functions, a base material, a preparation method of the gloves and a removing method of the gloves.
Background
The standard prevention refers to the integration of the characteristics of general prevention and substance isolation in vivo in hospitals, and the isolation is needed when the blood, body fluid, secretion and excrement of patients are determined to be infectious. Whether there is significant blood stain contamination or contact with non-intact skin and mucous membranes, the exposure to such substances must be a precautionary measure of protection. Contact isolation, spray isolation and air isolation are adopted according to the transmission path, and the method is a successful and effective measure for preventing nosocomial infection.
For the treatment, nursing or public facilities in hospitals, gloves, masks, isolation clothes and the like should be worn timely when the patients or pathogen carriers inevitably contact blood, body fluid, excrement, secretion and damaged skin mucosa. The timely wearing of the medical gloves can prevent viruses, flora or excrement of patients from directly or indirectly contacting, infecting or transferring to normal people. The gloves can effectively prevent medical staff from becoming a medium when the medical staff is infected with microorganisms, namely, prevent the medical staff from spreading pathogens polluted by patients or the environment in people. Gloves must be changed between two patients and cannot replace hand washing.
At present, medical gloves are classified into latex gloves, butyronitrile gloves, polyethylene gloves, polyvinyl chloride gloves and the like according to different materials. These gloves play an important role in hospitals and clinical operations. However, in daily life, many infectious diseases, such as acute hemorrhagic conjunctivitis, influenza, dysentery, SARS, novel coronavirus (COVID-19), etc., can be transmitted by direct contact or indirect contact. The scheme of diagnosis and treatment of pneumonia infected by novel coronavirus (trial fourth edition) published by Weijian Commission of China clearly indicates that the novel coronavirus can be transmitted by contact in addition to respiratory droplets. The common people prevent pneumonia infected by the novel coronavirus, and the most effective prevention mode is to wear gloves and masks frequently, so as to cut off direct transmission and indirect transmission ways.
Indirect contact propagation refers to propagation resulting from indirect contact with a contaminated article. The indirect contact is mainly achieved by contacting public articles infected with viruses, and the public articles generally need to be noticed, such as door handles, stair handrails, table tops, mobile phones, toys, notebook computers and public space table tops. The disposable gloves are the best measure for avoiding infection caused by indirect contact in public places besides the good habit of keeping hands in work.
The traditional disposable latex gloves and butyronitrile gloves have good bonding performance, strong mechanical property and good effect of preventing virus from spreading, but have the defects of high price and poor air permeability. Polyethylene gloves and polyvinyl chloride gloves are relatively cheap in material price, but relatively poor in flexibility and fitting capacity. Currently, all medical gloves need to be packaged specially, and even need to be sterilized. After the medical garbage is used, the medical garbage is required to be subjected to subsequent treatment, so that the environmental protection pressure is increased. At present, a portable spraying type antibacterial antiviral breathable invisible glove is lacked in the aspect of infectious disease control, particularly in the aspect of contact transmission disease control.
Disclosure of Invention
In order to solve the technical defects in the prior art, the invention provides a spraying type invisible breathable coating film with waterproof, antibacterial and antiviral functions, gloves, a base material and a glove preparation method and a cleaning method, which can effectively cut off pollution source propagation ways and improve the health level of people.
The technical solution adopted by the invention is as follows: the spray-type invisible breathable coating film with the waterproof, antibacterial and antiviral functions is prepared from a base material, wherein the base material comprises a copolymer of an acrylate derivative, isooctane, an organic antibacterial agent and an antiviral agent.
The spray-type invisible breathable gloves are prepared from glove base materials, wherein the glove base materials comprise a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The copolymer of the acrylate derivative is a copolymer of acrylate, vinyl polysiloxane, methacrylate and sodium acrylate.
The acrylate is one or more of methyl acrylate, ethyl acrylate and butyl acrylate.
The structural formula of the vinyl polysiloxane is as follows:
wherein n is 20-500; a + b is 20-500.
The methacrylate is one or more of methyl methacrylate, ethyl methacrylate and glycidyl methacrylate.
The organic antibacterial agent is one or more of acylaniline, imidazole, thiazole, isothiazolone derivative, quaternary ammonium salt, biguanidine and phenols.
The antiviral agent is luteolin, rutin, and lauric acid monoglyceride.
The molar ratio of the acrylate, the methacrylate, the vinyl polysiloxane and the sodium acrylate in the acrylate derivative copolymer is 30-50:40-20:25-10: 5-20.
A preparation method of a base material of a spray-type invisible breathable coating film with waterproof, antibacterial and antiviral functions comprises the following steps:
(1) preparation of copolymers of acrylate derivatives: weighing acrylic ester, methacrylic ester, vinyl polysiloxane and sodium acrylate according to the molar ratio of (30-50): 40-20): 25-10): 5-20, adding the acrylic ester, the methacrylic ester, the vinyl polysiloxane and the sodium acrylate into a dispersant, adding an azobisisobutyronitrile catalyst, reacting for 4-8h at 70-90 ℃ under the condition of air isolation to obtain a mixture, separating and purifying the obtained mixture to obtain the acrylic ester derivative copolymer with the molecular weight of 5000-80000
(2) Taking 1-30 parts of copolymer of acrylate derivatives, 68-97 parts of isooctane, 1-2 parts of organic antibacterial agent and 1-2 parts of antiviral agent, mixing uniformly, and fully dissolving to obtain the base material of the invisible breathable glove.
The addition amount of the catalyst is 0.05-2% of the total mass sum of the acrylate, the methacrylate, the vinyl polysiloxane and the sodium acrylate.
The dispersing agent is one or more of cyclohexane, normal hexane, normal heptane and isooctane.
A preparation method of spray-type invisible breathable gloves with waterproof, antibacterial and antiviral functions comprises the following steps: and (3) stretching the palm and the five fingers, uniformly spraying the base material of the glove on the front and back surfaces of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, naturally airing for 10-20 seconds to form a film or blow-drying, and quickly forming the film within 1-10 seconds to form the invisible glove with the functions of water resistance, air permeability, bacteria resistance and virus resistance.
A method for removing a spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions comprises the following steps: the cleaning agent is uniformly sprayed on the palm, finger space, finger tip and wrist, and the invisible gloves can be removed by gently rubbing the hands, and washing with clear water for 2-3 times.
The scavenger is one or more of 50-80% ethanol water solution and 40-90% isopropanol water solution.
The invention has the beneficial effects that: the invention provides a spraying type invisible breathable coating film with waterproof, antibacterial and antiviral functions, gloves, a base material and a preparation method and a removal method of the gloves. Particularly in the aspect of preventing and treating contact transmission diseases, the invention relates to a portable spraying type antibacterial antiviral breathable invisible glove and technology. The invisible gloves designed by the invention are suitable for public places such as hospitals, nursing, catering, buses, households, travels and the like to prevent pathogen transmission caused by direct contact or indirect contact, can effectively cut off pollution source transmission ways, and improve the health level of people.
Drawings
FIG. 1 is a schematic view of a spraying method of a spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions.
FIG. 2 is a total reflection infrared spectrum of the spray-type invisible breathable glove substrate with waterproof, antibacterial and antiviral functions obtained in example 1.
FIG. 3 shows the antibacterial effect of the spray-on type invisible air-permeable gloves with waterproof, antibacterial and antiviral functions obtained in examples 1-6, wherein Escherichia coli is used as a model bacterium, and the antibacterial effect is good.
FIG. 4 shows the antibacterial effect of the spray-on type invisible breathable gloves with waterproof, antibacterial and antiviral functions obtained in examples 1-6, and the spray-on type invisible breathable gloves with waterproof, antibacterial and antiviral functions have good antibacterial effect by taking Staphylococcus aureus as a model bacterium.
FIG. 5 shows the results of the cytotoxicity tests of the leaching solutions of the contact glove substrates obtained in examples 1 to 6, wherein the cytotoxicity rating of the contact glove substrate is 0, i.e., no cytotoxicity.
Detailed Description
The present invention is further illustrated by the following examples, which are provided to enable those skilled in the art to better understand the present invention and are not intended to limit the present invention in any way.
Example 1
A spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of methyl acrylate, vinyl polysiloxane, methyl methacrylate and sodium acrylate, the structural formula of the vinyl polysiloxane is shown in (I-a), and n is 20;
the preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing methyl acrylate, methyl methacrylate, vinyl polysiloxane and sodium acrylate according to the molar ratio of 30:40:10:20, adding the weighed methyl acrylate, methyl methacrylate, vinyl polysiloxane and sodium acrylate into cyclohexane, adding an azodiisobutyronitrile catalyst, and reacting for 4 hours at 70 ℃ under the condition of air isolation;
the addition amount of the catalyst was 0.05% of the total mass of methyl acrylate, methyl methacrylate, vinyl polysiloxane and sodium acrylate.
(2) Separating and purifying the mixture obtained in the step (1) to obtain an acrylate derivative copolymer with the molecular weight of 5000, wherein the acrylate derivative copolymer is shown in figure 2 and is a total reflection infrared spectrum of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: taking 1 part of acrylate derivative copolymer, 97 parts of isooctane, 1 part of organic antibacterial agent and 1 part of antiviral agent, uniformly mixing, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent is benzalkonium chloride, and the antiviral agent is luteolin and rutin in a mass ratio of 1: 1.
The preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
method for the preparation of a contact glove (fig. 1): spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 10 seconds to form a film. In emergency, the glove can be dried, and a film is rapidly formed within 1 second, so that the invisible glove with waterproof, breathable, antibacterial and antiviral functions is formed;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed after the hands gently rub the cleaning agent and the cleaning agent is washed for 2 times by clear water. The scavenger is 50% ethanol water solution.
Example 2
A spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of ethyl acrylate, vinyl polysiloxane, ethyl methacrylate and sodium acrylate;
the structural formula of the vinyl polysiloxane is shown as (I-b), and n is 500;
the preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing ethyl acrylate, ethyl methacrylate, vinyl polysiloxane and sodium acrylate according to the molar ratio of 50:20:25:5, adding the ethyl acrylate, the ethyl methacrylate, the vinyl polysiloxane and the sodium acrylate into n-hexane, adding an azodiisobutyronitrile catalyst, and reacting for 8 hours at 90 ℃ under the condition of air isolation;
the addition amount of the catalyst is 2 percent of the total mass sum of the ethyl acrylate, the ethyl methacrylate, the vinyl polysiloxane and the sodium acrylate.
(2) Separating and purifying the mixture obtained in the step (1) to obtain the acrylate derivative copolymer with the molecular weight of 80000.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: and (3) uniformly mixing 30 parts of acrylate derivative copolymer, 68 parts of isooctane, 1 part of organic antibacterial agent and 1 part of antiviral agent, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent is ketoconazole; antiviral agents: lauric acid monoglyceride.
The preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
method for the preparation of a contact glove (fig. 1): spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 20 seconds to form a film. In emergency, the glove can be dried, and a film is rapidly formed within 10 seconds to form the invisible glove with waterproof, breathable, antibacterial and antiviral functions;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed by washing with clear water for 3 times after the hands gently rub the cleaning agent.
The scavenger is a 40% isopropanol aqueous solution.
Example 3:
a spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of butyl acrylate, vinyl polysiloxane, glycidyl methacrylate and sodium acrylate,
the structural formula of the vinyl polysiloxane is shown as (I-c), and a + b is 20
The preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing butyl acrylate, glycidyl methacrylate, vinyl polysiloxane and sodium acrylate according to the molar ratio of 40:30:20:10, adding the butyl acrylate, glycidyl methacrylate, vinyl polysiloxane and sodium acrylate into n-heptane, adding an azodiisobutyronitrile catalyst, and reacting for 5 hours at 80 ℃ under the condition of isolating air;
the addition amount of the catalyst is 0.8 percent of the total mass sum of the butyl acrylate, the glycidyl methacrylate, the vinyl polysiloxane and the sodium acrylate.
(2) Separating and purifying the mixture obtained in the step (1) to obtain the acrylate derivative copolymer with the molecular weight of 20000.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: and (3) taking 26 parts of acrylate derivative copolymer, 70 parts of isooctane, 2 parts of organic antibacterial agent and 2 parts of antiviral agent, uniformly mixing, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent is moroxydine and methylphenol in a mass ratio of 1:1, and the antiviral agent is rutin and lauric acid monoglyceride in a mass ratio of 2: 1.
The preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
method for the preparation of a contact glove (fig. 1): spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 15 seconds to form a film. In emergency, the glove can be dried, and a film is rapidly formed within 5 seconds, so that the invisible glove with waterproof, breathable, antibacterial and antiviral functions is formed;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed after the hands gently rub the cleaning agent and the cleaning agent is washed for 2 times by clear water.
The scavenger is 80% ethanol water solution.
Example 4
A spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of methyl acrylate, vinyl polysiloxane, butyl methacrylate and sodium acrylate;
the structural formula of the vinyl polysiloxane is shown as (I-d), wherein a + b is 500:
the preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing methyl acrylate, butyl methacrylate, vinyl polysiloxane and sodium acrylate according to the mol ratio of 30:20:25:5, adding the methyl acrylate, the butyl methacrylate, the vinyl polysiloxane and the sodium acrylate into n-heptane and isooctane according to the volume ratio of 2:1, adding an azobisisobutyronitrile catalyst, and reacting for 6 hours at 80 ℃ under the condition of isolating air;
the addition amount of the catalyst is 1.5 percent of the total mass sum of methyl acrylate, butyl methacrylate, vinyl polysiloxane and sodium acrylate.
(2) Separating and purifying the mixture obtained in the step (1) to obtain the acrylate derivative copolymer with the molecular weight of 50000.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: taking 3 parts of acrylate derivative copolymer, 94 parts of isooctane, 1.5 parts of organic antibacterial agent and 1.5 parts of antiviral agent, mixing uniformly, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent is isothiazolone, moroxydine and methylphenol in a mass ratio of 1:1: 1. The antiviral agent is luteolin and lauric acid monoglyceride at a mass ratio of 1: 1. :
the preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
method for the preparation of a contact glove (fig. 1): spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 20 seconds to form a film. In emergency, the glove can be dried, and a film is rapidly formed within 10 seconds to form the invisible glove with waterproof, breathable, antibacterial and antiviral functions;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed by washing with clear water for 3 times after the hands gently rub the cleaning agent.
The scavenger is a 90% isopropanol aqueous solution.
Example 5
A spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of methyl acrylate, vinyl polysiloxane, ethyl methacrylate and sodium acrylate;
the structural formula of the vinyl polysiloxane is shown as (I-a), and n is 300;
the preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing methyl acrylate, ethyl methacrylate, vinyl polysiloxane and sodium acrylate according to the molar ratio of 40:30:20:10, adding the weighed materials into a mixed solution of cyclohexane and isooctane in the volume ratio of 2:1, adding an azodiisobutyronitrile catalyst, and reacting for 6 hours at 80 ℃ under the condition of air isolation;
the addition amount of the catalyst is 1.2 percent of the total mass sum of the methyl acrylate, the ethyl methacrylate, the vinyl polysiloxane and the sodium acrylate.
(2) Separating and purifying the mixture obtained in the step (1) to obtain the acrylic ester derivative copolymer with the molecular weight of 8000.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: taking 25 parts of acrylate derivative copolymer, 72 parts of isooctane, 1 part of organic antibacterial agent and 2 parts of antiviral agent, uniformly mixing, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent: the mass ratio of the acylaniline to the thiazole to the benzalkonium chloride to the parachlorometaxylenol is 2:2:1: 1. The antiviral agent is luteolin, rutin and lauric acid monoglyceride with the mass ratio of 3:3: 1.
The preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
the preparation method of the invisible glove comprises the following steps: spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 10 seconds to form a film. In emergency, the glove can be dried, and a film is rapidly formed within 10 seconds to form the invisible glove with waterproof, breathable, antibacterial and antiviral functions;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed by washing with clear water for 3 times after the hands gently rub the cleaning agent.
The scavenger is: an 80% ethanol aqueous solution and a 90% isopropanol aqueous solution in a mass ratio of 1: 1.
Example 6
A spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions is characterized by comprising a copolymer of acrylate derivatives, isooctane, an organic antibacterial agent and an antiviral agent.
The acrylate derivative copolymer is a copolymer of methyl acrylate, vinyl polysiloxane, glycidyl methacrylate and sodium acrylate; the structural formula of the vinyl polysiloxane is (I-d), wherein a + b is 300;
the preparation method of the copolymer of the acrylic ester derivative comprises the following steps:
(1) weighing methyl acrylate, glycidyl methacrylate, vinyl polysiloxane and sodium acrylate according to the molar ratio of 40:30:20:10, adding the methyl acrylate, the glycidyl methacrylate, the vinyl polysiloxane and the sodium acrylate into isooctane, adding an azodiisobutyronitrile catalyst, and reacting for 8 hours at 70 ℃ under the condition of air isolation;
the addition amount of the catalyst is 0.1 percent of the total mass sum of the methyl acrylate, the glycidyl methacrylate, the vinyl polysiloxane and the sodium acrylate.
(2) Separating the mixture obtained in step (1), and purifying to obtain acrylate derivative copolymer with molecular weight of 10000.
The preparation method of the spray-type invisible breathable glove base material with the waterproof, antibacterial and antiviral functions comprises the following steps: taking 15 parts of acrylate derivative copolymer, 81 parts of isooctane, 2 parts of organic antibacterial agent and 2 parts of antiviral agent, mixing uniformly, and fully dissolving to obtain the invisible breathable glove base material.
The organic antibacterial agent is thiazole, benzalkonium chloride and parachlorometaxylenol in a mass ratio of 2:2:1, and the antiviral agent is lauric acid monoglyceride.
The preparation and cleaning method of the spray-coating type invisible gloves comprises the following steps:
method for the preparation of a contact glove (fig. 1): spreading the palm and five fingers, uniformly spraying on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and naturally drying for 14 seconds to form a film. In emergency, the glove can be blown dry, and can form a film quickly within 6 seconds to form the invisible glove with waterproof, breathable, antibacterial and antiviral functions;
the method for removing the invisible gloves comprises the following steps: the cleaning agent is uniformly sprayed on the palm, the finger space, the finger tip and the wrist, and the invisible gloves can be removed by washing with clear water for 3 times after the hands gently rub the cleaning agent.
The scavenger is a 60% ethanol aqueous solution and a 70% isopropanol aqueous solution in a mass ratio of 4: 1.
Experimental example 1 contact Angle experiment
The base material solutions of the contact gloves obtained in examples 1 to 6 were uniformly sprayed on the surface of a glass slide, and after the solvent was evaporated, the hydrophilic and hydrophobic properties of the resulting films were measured using a contact angle measuring instrument (Biolin Scientific equipment, sweden). As shown in table 1, the contact angles of the base materials of the contact gloves according to the present invention were all greater than 90 °, and the base materials were hydrophobic materials.
Table 1 shows the results of the hydrophobicity characterization of the contact glove substrates obtained in examples 1-6.
Experimental example 2 bacteriostatic test
The bacteria are selected from escherichia coli and staphylococcus aureus as model bacteria.
mu.L of the gel prepared according to examples 1-6 were added to each well of a 48-well plate, and after complete gelling, 10. mu.L of E.coli (or Staphylococcus aureus) bacterial suspension (10) was added to each well6CFU/mL) on the gel surface, incubated at 37 ℃ for 2h, followed by addition of 1mL PBS per well to resuspend the bacteria in 10. mu.L of broth (10. mu.L)6CFU/mL) was dissolved in 1mL of PBS as a control group, followed by incubation for 24h, and then, after 40. mu.L of each well was taken out and incubated for 24h at 37 ℃ on an agar plate, the growth of bacteria on the surface of the agar plate was observed. Fig. 3 shows the antibacterial effect of the spray-on type invisible breathable gloves with waterproof, antibacterial and antiviral functions obtained in examples 1-6, and the results show that the antibacterial rate of the base material obtained in examples 1-6 can reach more than 98% for escherichia coli, and the base material has a good antibacterial effect against escherichia coli. FIG. 4 shows a water-proof, antibacterial and antiviral agent obtained from examples 1-6The antibacterial effect of the spray-type invisible breathable gloves is that the antibacterial rate of the base materials obtained in the examples 1-6 can reach over 99.2% aiming at staphylococcus aureus, which shows that the materials obtained in the examples 1-6 have good effect of resisting staphylococcus aureus.
Experimental example 3 cytotoxicity test
And (3) adopting the L929 cell line cells, continuously culturing for 48h, and enabling the cells to grow in a complete adherent manner.
Negative control (fresh sterile RAPI1640 medium containing 10% fetal bovine serum), and positive control (5% phenol solution by mass fraction). Experimental group (0.1 g of the invisible glove substrate described in examples 1-6 was added to 10mL of RAPI1640 medium containing 10% fetal bovine serum, incubated at 37 ℃ and extracted for 24 hours).
The assay was performed in 96-well plates with an initial culture medium L929 cell density of 5X 104cell/mL, 200. mu.L of cell culture medium per well, approximately 10000 cells per well. And (4) three multiple holes. The culture was carried out at 37 ℃ under 5% (V/V) carbon dioxide/air for 24 hours, and then the original medium was discarded. Negative control group: add 200. mu. LRAPI1640 medium (containing 10% fetal bovine serum); respectively adding 20 μ L, 40 μ L, 60 μ L, 80 μ L and 100 μ L of 5% phenol solution into the positive control group, and supplementing RAPI1640 culture medium (containing 10% fetal calf serum) until the volume of each well reaches 200 μ L; the experimental groups were added with 20. mu.L, 40. mu.L, 60. mu.L, 80. mu.L, 100. mu.L of the leaching solution, respectively, and supplemented with RAPI1640 medium (containing 10% fetal bovine serum) until the volume of each well reached 200. mu.L. After the 96-well plate was further cultured for 48 hours, the culture solution was discarded, 20. mu.L of MTT solution was added to each well, and after 4 hours of culture, the stock solution was discarded, 150. mu.L of dimethyl sulfoxide was added thereto, and the mixture was shaken for 10 minutes to measure the absorbance value (ABS) (570nm wavelength). Relative cell viability was calculated using the following formula:
the experimental results show that:
as shown in FIG. 5, the relative cell viability of the leaching solutions of the contact glove substrates obtained in examples 1 to 6 is greater than 82% under the condition of 50 μ g/mL, and the cytotoxicity rating of the contact glove substrates obtained in examples 1 to 6 is 0 and has no cytotoxicity according to the GB/T16886.5-2003 in vitro cytotoxicity evaluation standard.
The coating film of the invention can also be used for protecting the surfaces of other articles such as handrails and the like.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.
Claims (7)
1. The spray-type invisible breathable gloves with the waterproof, antibacterial and antiviral functions are characterized in that the spray-type invisible breathable gloves are prepared from a base material, the base material comprises 1-30 parts of copolymer of acrylate derivatives, isooctane, 68-97 parts of isooctane, 1-2 parts of organic antibacterial agent and 1-2 parts of antiviral agent, the copolymer of the acrylate derivatives is copolymer of acrylate, vinyl polysiloxane, methacrylate and sodium acrylate, and the molar ratio of the acrylate, the methacrylate, the vinyl polysiloxane and the sodium acrylate in the copolymer of the acrylate derivatives is 30-50:40-20:25-10: 5-20.
2. The spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions according to claim 1, wherein the acrylate is one or more of methyl acrylate, ethyl acrylate and butyl acrylate.
3. The spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions as claimed in claim 1, wherein the vinyl polysiloxane has the structural formula:
wherein n = 20-500; a + b = 20-500.
4. The spray-type invisible breathable glove with waterproof, antibacterial and antiviral functions according to claim 1, wherein the methacrylate is one or more of methyl methacrylate, ethyl methacrylate and glycidyl methacrylate.
5. The method for preparing the spray-type invisible breathable glove with the waterproof, antibacterial and antiviral functions as claimed in claim 1, is characterized by comprising the following steps:
(1) preparation of copolymers of acrylate derivatives: weighing acrylic ester, methacrylic ester, vinyl polysiloxane and sodium acrylate according to the molar ratio of (30-50) to (40-20) to (25-10) to (5-20), adding the acrylic ester, the methacrylic ester, the vinyl polysiloxane and the sodium acrylate into a dispersing agent, adding an azobisisobutyronitrile catalyst, wherein the addition amount of the catalyst is 0.05-2% of the total mass of the acrylic ester, the methacrylic ester, the vinyl polysiloxane and the sodium acrylate, reacting for 4-8h at 70-90 ℃ under the condition of air isolation to obtain a mixture, and separating and purifying the obtained mixture to obtain a copolymer of the acrylic ester derivative with the molecular weight of 5000-80000;
(2) taking 1-30 parts of copolymer of acrylate derivatives, 68-97 parts of isooctane, 1-2 parts of organic antibacterial agent and 1-2 parts of antiviral agent, mixing uniformly, and fully dissolving to obtain the base material of the invisible breathable glove.
6. The method for preparing the spray-type invisible breathable glove with the waterproof, antibacterial and antiviral functions as claimed in claim 1, is characterized by comprising the following steps: the palm and five fingers are opened, the base material of the glove is evenly sprayed on the front and back sides of the palm, the finger space, the finger tips and the exposed part of the wrist according to the size of the palm, and the glove is naturally dried for 10 to 20 seconds to form a film or is dried for blowing, and the film is rapidly formed within 1 to 10 seconds, so that the invisible breathable glove with the waterproof, breathable, antibacterial and antiviral functions is formed.
7. The method for removing the spray-on invisible breathable glove with waterproof, antibacterial and antiviral functions as claimed in claim 1, which comprises the following steps: the invisible breathable gloves can be removed by uniformly spraying a scavenging agent on palms, interphalangeals, fingertips and wrists, gently rubbing the palms, the fingertips and the wrists, and washing the palms with clear water for 2 to 3 times, wherein the scavenging agent is one or more of 50 to 80 percent ethanol water solution and 40 to 90 percent isopropanol water solution.
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| CN1487023A (en) * | 2003-07-30 | 2004-04-07 | 谢建康 | Long-acting antiseptic and antiviral transparent protecting film and its production process |
| CN101195041A (en) * | 2006-12-07 | 2008-06-11 | 东莞太力生物工程有限公司 | Film forming solution for adelomorphic protecting film |
| WO2010084315A1 (en) * | 2009-01-20 | 2010-07-29 | The University Of Bath | Antimicrobial coatings |
| WO2010126883A1 (en) * | 2009-04-27 | 2010-11-04 | Georgia Tech Research Corporation | Durable skin marking compositions |
| CN102796230A (en) * | 2011-05-24 | 2012-11-28 | 武汉强力荷新材料有限公司 | Method for preparing silicone acrylic emulsion with high solid content and high silicon content |
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2020
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| CN1487023A (en) * | 2003-07-30 | 2004-04-07 | 谢建康 | Long-acting antiseptic and antiviral transparent protecting film and its production process |
| CN101195041A (en) * | 2006-12-07 | 2008-06-11 | 东莞太力生物工程有限公司 | Film forming solution for adelomorphic protecting film |
| WO2010084315A1 (en) * | 2009-01-20 | 2010-07-29 | The University Of Bath | Antimicrobial coatings |
| WO2010126883A1 (en) * | 2009-04-27 | 2010-11-04 | Georgia Tech Research Corporation | Durable skin marking compositions |
| CN102796230A (en) * | 2011-05-24 | 2012-11-28 | 武汉强力荷新材料有限公司 | Method for preparing silicone acrylic emulsion with high solid content and high silicon content |
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